21. Early Diagnosis Of Central Pontine Myelinolysis With Early Diagnosis of central pontine myelinolysis with DiffusionWeighted Imaging Kimberly A. Ruzeka , Norbert G. Campeaua and Gary M. Millera http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

22. Metabolic Disorders: Central Pontine Myelinolysis, Marchiafava-Bignami Disease Neuropathology of MarchiafavaBignami Disease and central pontine myelinolysis. http://www.neuropat.dote.hu/alcoh.htm

Metabolic Disorders Marchiafava-Bignami disease Case 1 Case 2 Related Internet Resources MRI Images - University of Florida, US Central pontine myelinolysis Case 1 Related Internet Resources Myelinolysis after Correction of Hyponatremia, Annals of Internal Medicine, 1997, 126:57-62 Other Resources Central Pontine Myelinolysis, eMedicine Demyelinating Diseases - Internet Handbook of Neurology Toxic Disorders - Internet Handbook of Neurology var site="sm5hegeduskdote" Last modified: February 17, 2001 If you have any comments, please, contact Neuroanatomy Structures Online Neuropathology Atlas Internet Handbook of Neurology

23. Demyelinating Diseases - Internet Handbook Of Neurology central pontine myelinolysis. central pontine myelinolysis eMedicine/Neurology;central pontine myelinolysis - Singapore Med J 2000; Vol 41(1) http://www.neuropat.dote.hu/myelin.htm

Internet Handbook of Neurology Compiled by K atalin H Department of Neurology University of Debrecen, Hungary Demyelinating Diseases Chapters: A Collection of High Quality Online Resources for Health Professionals Pathology see Pathology of Infectious Diseases and Disease of Myelin Overview - Washington University Disorders of Myelination - University of Berkeley Demyelinating Diseases of the Brain - University of California, San Diego Pathology of Inflammatory Demyelinating Diseases - Mayo Clinic Is There a Role for Human Herpesvirus-6 in the Course of Multiple Sclerosis? - International Journal of MS Care, March Multiple Sclerosis Overview Multiple Sclerosis - Neurology Associates of Arlington Multiple Sclerosis - Praxis MD Multiple Sclerosis: Current Status and Strategies for the Future - National Academy Press, Multiple Sclerosis: Lectures - University of Utah, Houston ( epidemiology, pathology, etiology, laboratory findings, clinical presentation, diagnostic criteria, classification, differential diagnosis, treatment options, prognosis Multiple Sclerosis - Bhatia General Hospital, Mumbai, IN

24. Central Pontine Myelinolysis - Washington DC central pontine myelinolysis Washington Hospital Center is located in Washington DC. http://www.whcenter.org/14613.cfm

cddcodebase = "navtools/topmenu/";cddcodebase367050 = "navtools/topmenu/"; Article Manager Home Back to Health Library Print This Page ... Central nervous system Central pontine myelinolysis Definition: Central pontine myelinolysis is nerve damage caused by the destruction of the layer ( myelin sheath ) covering nerve cells in the brainstem (pons). Alternative Names: CPM Causes, incidence, and risk factors: The destruction of the myelin sheath that coats nerve cells prevents signals from being properly conducted within the nerve. This decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast. It also can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur on its own. It is a complication of treatment for other conditions or the other conditions themselves. People at risk include those with low sodium levels from any cause

25. ► Central Pontine Myelinolysis A medical encycopedia article on the topic central pontine myelinolysis. http://www.umm.edu/ency/article/000775.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Encyclopedia (English) Toggle English Spanish Central pontine myelinolysis Overview Symptoms Treatment Prevention Definition: Central pontine myelinolysis is a condition characterized by nerve damage caused by the destruction of the covering layer ( myelin sheath) of nerve cells in the brainstem (pons). Alternative Names: CPM Causes, incidence, and risk factors: The destruction of the myelin sheath that coats nerves inhibits impulse conduction within the cell and thus decreases its ability to communicate with other cells. The most common cause of central pontine myelinolysis is a rapid, drastic change in sodium levels in the body. Most commonly, this occurs when someone is being treated for low levels of sodium ( hyponatremia ) and the levels rise too fast, but it can occasionally occur when high levels of sodium in the body (hypernatremia) are corrected too quickly. This condition does not occur spontaneously; it is a complication of either treatment for other conditions or the other conditions themselves. Risks include hyponatremia from any cause.

26. ► Central Pontine Myelinolysis A medical encycopedia article on the topic central pontine myelinolysis. http://www.umm.edu/ency/article/000775trt.htm

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Disease Nutrition Surgery Symptoms Injury ... Encyclopedia (English) Toggle English Spanish Central pontine myelinolysis Overview Symptoms Treatment Prevention Alternative Names: CPM Treatment: This is an emergency disorder that requires hospitalization for initial diagnosis and treatment. There is no known cure for central pontine myelinolysis and treatment is focused on relieving symptoms. Double vision may be reduced with the use of an eye patch. Physical therapy may help maintain muscle strength, mobility and function in weakened arms and legs. Expectations (prognosis): The neurologic damage caused by central pontine myelinolysis is usually persistent. The disorder can cause serious chronic disability. Complications: Permanent neurologic losses Decreased ability to work or care for self Decreased ability to interact with others Calling your health care provider: Go to the emergency room or call the local emergency number (such as 911) if seizures muscle weakness , or other symptoms of central pontine myelinolysis occur. Central nervous system Review Date: 7/28/2002 Reviewed By: Elaine T. Kiriakopoulos, M.D., MSc, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

27. Central Pontine Myelinolysis Patient medical question and answer from The Neurology and Neurosurgery Forum.Health topic area and articles about traumatic brain injury Topics ,brain, http://www.medhelp.org/forums/neuro/messages/30819.html

Questions in The Neurology Forum are being answered by doctors from The Cleveland Clinic , consistently ranked one of the best hospitals in America. Central Pontine Myelinolysis Forum: The Neurology and Neurosurgery Forum Topic: Traumatic Brain Injury Subject: Central Pontine Myelinolysis From To Post gsoh Her cognitive abilities were not affected albeit minor behavioral change. She has improved from assisted standing to self-gait walking (500 meters) over 6 weeks. Able to stand up on her own from a few limited sitting positions. Her right hand is able to hold a small cup of water. Taking a deep breath to hold on is still a difficulty. Rollover on bed is still very difficult. The strongest part of the four limbs at right leg is still having difficulty for coordinated movement. She was discharged on 23/8/00 and being 24 hours attended in the home. I am obviously more interested to know any chances of speeding up the process of re-myelination before it is too late. I started reading about the myelin reformation. Unfortunately, I cannot find any resources that confirm positively the process in adult brain cells. Nor is there any authority to rule out the process or point to the timing of a brain damage like CPM or other brain disorders. I started giving her Omega-3 oil, colloidal form minerals, Vitamin B6, B12. I read about IgG that may act with adult Oligodendroglia for the re-myelination process. So I give her chewable tablets of colostrums which contained high concentration of Immunoglobulin G. All these, being health food supplements, in my mind, should have minimal side effects.

28. Central Pontine Myelinolysis Patient medical question and answer from The Neurology and Neurosurgery Forum.Health topic area and articles about myelin Topics ,pons, brain, stroke. http://www.medhelp.org/forums/neuro/messages/30435.html

Questions in The Neurology Forum are being answered by doctors from The Cleveland Clinic , consistently ranked one of the best hospitals in America. central pontine myelinolysis Forum: The Neurology and Neurosurgery Forum Topic: Myelin Subject: central pontine myelinolysis From To Post Ottilie Would like to know if any research is being done on this disease on the brain stem (pons). I have it plus it has caused down beat nystagmus which prevents me from driving. The psychological impact is terrible. I also would like to find someone with this disease. So far I have not. CCF Neuro[P] MD, RPS Ottilie Dear Ottilie: Central pontine myelinosis is usually results from changes in the osmolarity (electrolyte and protein concentration) in the brain versus the blood stream. The abnormal difference between the two causes the myelin surrounding the nerve processes to become unraveled. This inturn causes dysfunction of the nerves in this area. This is not a disease, but the result from an abnormality. Pontine problems can also arise from stroke in the pons. This will give similar symptoms (although much more focal, such as only downbeat mystagmus). If the stroke is large enough, it can cause complete loss of most movement below the eyes.

29. Accessing Article Bone Marrow Transplantation is a high quality, peerreviewed journal coveringall aspects of clinical and basic haemopoietic stem cell transplantation. http://www.nature.com/bmt/journal/vaop/ncurrent/full/1705115a.html

NATURE.COM NEWS@NATURE.COM NATUREJOBS NATUREEVENTS ... Help E-MAIL: PASSWORD: Save password Forgotten password? Most users gain access to full text articles through a site license. This is available to institutional customers only. For further information visit the Librarian Gateway. Full-text articles are also available through a number of other options: I want to purchase this article Select this option to view this article immediately and access it for seven days. Price: US$30* In order to purchase this article you must be a registered user. Click here to register or log in above. I want to subscribe to Bone Marrow Transplantation Select this option to purchase a personal subscription. I am already a personal subscriber to Bone Marrow Transplantation Personal subscribers to Bone Marrow Transplantation can view this article. To do this you need to associate your subscription with your registration via the My Account page. If you already have an active online subscription, log in via the login box in the top right-hand corner of this page. You can request the document from a number of document delivery services: British Library Document Supply Centre CISTI Canadian Institute for Scientific and Technical Information Infotrieve Thomson ISI Document Delivery You can also request the document from your local library through interlibrary loan services.

30. Bone Marrow Transplantation - Abstract Of Article: Central Pontine Myelinolysis central pontine myelinolysis following bone marrow transplantation complicatedby severe hepatic venoocclusive disease. C Fraser1, L Charnas2 and P Orchard http://www.nature.com/bmt/journal/vaop/ncurrent/abs/1705115a.html

@import "/common/style/layout.css";/* do not edit this stylesheet */ @import "/common/style/main.css";/* do not edit this stylesheet */ @import "/aj/style/group.css";/* do not edit this stylesheet */ @import "/bmt/style/site.css";/* edit this stylesheet only */ Accessibility statement Jump to main content Jump to main navigation Jump to search ... ABOUT NPG E-MAIL: PASSWORD Save password Forgotten password? MY ACCOUNT E-ALERTS SUBSCRIBE ... REGISTER Text to search for Advanced search Journal home Advance online publication 25 July 2005 Abstract Correspondence Bone Marrow Transplantation advance online publication 25 July 2005; doi: 10.1038/sj.bmt.1705115 Central pontine myelinolysis following bone marrow transplantation complicated by severe hepatic veno-occlusive disease C Fraser , L Charnas and P Orchard Pediatric Blood and Marrow Transplant Program, University of Minnesota, MN, USA Division of Pediatric Neurology, University of Minnesota, MN, USA Main navigation Journal home Advance online publication About AOP Current issue ... Site features NPG resources Oncogene Leukemia British Journal of Cancer Nature Reviews Cancer ... Nature Medicine NPG Subject areas Biotechnology Cancer Chemistry Dentistry ... Browse all publications Extra navigation ABSTRACT NAVIGATION - ABSTRACT Table of contents Full text Download PDF Send to a friend ... products enter buyers guide search text here ADVERTISEMENT Bone Marrow Transplantation Journal home Advance Online Publication Table of contents Archive ... Site index

31. Central Pontine Myelinolysis a CHORUS notecard document about central pontine myelinolysis. http://chorus.rad.mcw.edu/doc/00066.html

CHORUS Collaborative Hypertext of Radiology Nervous system About CHORUS Search Feedback central pontine myelinolysis toxic demyelination rapid correction of hyponatremia low density in central pons variable size may have paired, rounded lesions enhances in acute phase See also: demyelinating diseases white-matter diseases Charles E. Kahn, Jr., MD - 2 February 1995 Last updated 26 May 2004 Related CHORUS documents: demyelinating disease Schilder syndrome disseminated necrotizing leukoencephalopathy Binswanger disease ... white-matter disease Search for related articles: AJR American Journal of Roentgenology PubMed : index to biomedical literature ... Medical College of Wisconsin

32. Central Pontine Myelinolysis central pontine myelinolysis. toxic demyelination; rapid correction of hyponatremia.low density in central pons. variable size; may have paired, http://chorus.rad.mcw.edu/to-go/00066.html

central pontine myelinolysis toxic demyelination rapid correction of hyponatremia low density in central pons variable size may have paired, rounded lesions enhances in acute phase See also: demyelinating diseases white-matter diseases Home Nervous system

33. Hyponatremia And Central Pontine Myelinolysis -- Burcar Et Al. 27 (3): 223 -- Ne Autopsy in a patient with severe hyponatremia showed central pontine myelinolysis.Review of our patients with central pontine myelinolysis and those http://www.neurology.org/cgi/content/abstract/27/3/223

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Burcar, P. J. Articles by Yarnell, P. R. ARTICLES Hyponatremia and central pontine myelinolysis PJ Burcar, MD Norenberg and PR Yarnell Autopsy in a patient with severe hyponatremia showed central pontine myelinolysis. Review of our patients with central pontine myelinolysis and those described in the English literature to data disclosed that 61 percent had documented hyponatremia. While the exact mechanism involving hyponatremia and central pontine myelinolysis cannot be defined, a circumstantial relationship is apparent. The purpose of this paper is to emphasize this relationship and to suggest that the possibility of central pontine myelinolysis be considered in any patient with hyponatremia and neurologic dysfunction.

34. Neurology -- Sign In Page Diuretic abuse and central pontine myelinolysis. Psychother Psychosom 1989;52101–105 . central pontine myelinolysis in a patient with bulimia. http://www.neurology.org/cgi/content/full/64/12/2156

HOME HELP FEEDBACK SUBSCRIPTIONS ... SEARCH QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This item requires a subscription to Neurology Online. Full Text Pontine/extrapontine myelinolysis occurring in the setting of an eating disorder Singer et al. Neurology. This Article Full Text (PDF) Correspondence: Submit a response ... Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Download to citation manager PubMed PubMed Citation Articles by Singer, C. Articles by Bowen, B. Related Collections MRI All Medical/Systemic disease Gastrointestinal Nutritional To view this item, select one of the options below: Sign In User Name Sign in without cookies. Can't get past this page? Help with Cookies. Need to Activate? Password Forgot your user name or password? Purchase Short-Term Access Pay per Article - You may access this article (from the computer you are currently using) for 1 day for US$20.00

35. Penn State Faculty Research Expertise Database (FRED) central pontine myelinolysis, Extrapontine Myelinolysis. Extrapontine Myelinoclasis,Myelinoclasis, Central Pontine. Pontine Myelinolysis, Central, Central http://fred.hmc.psu.edu/ds/retrieve/fred/meshdescriptor/D017590

36. HighWire -- Browse Journals - Central Pontine Myelinolysis Browse Journals publishing on central pontine myelinolysis, (return to Topic List Alphabet, , Frequency of articles in central pontine myelinolysis http://highwire.stanford.edu/lists/topic_dir/608683/618131/620438/620972/620985/

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37. NDI Terminology - Central Pontine Myelinolysis NDI Foundation. central pontine myelinolysis. DEFINITION. Definition has yet tobe entered. Check back later. The definitions used in this glossary of http://www.ndif.org/Terms/central_pontine_myelinolysis.html

central pontine myelinolysis DEFINITION: Definition has yet to be entered. Check back later. The definitions used in this glossary of terminology either have been provided by the authors of the articles, or have been extracted wholly or in part, or paraphrased from the following sources: The American Medical Association Encyclopedia of Medicine , Charles B. Clayman, MD, Medical Editor, Random House, New York, 1989; Dorland's Illustrated Medical Dictionary , 28th Edition, W. B. Saunders Company, Philadelphia, 1994; The Random House Dictionary of the English Language , Unabridged Edition, 1966; Webster's Ninth New Collegiate Dictionary TERMINOLOGY WHERE THIS WORD IS USED TABLE of CONTENTS INFO. REQUEST ENTRANCE

38. Central Pontine Myelinolysis - General Practice Notebook central pontine myelinolysis (CPM) is a rare demyelinating condition of the ponsaffecting. long tract fibres; pontocerebellar fibres; pontine nuclei http://www.gpnotebook.co.uk/cache/-1583742920.htm

central pontine myelinolysis Central pontine myelinolysis (CPM) is a rare demyelinating condition of the pons affecting: long tract fibres pontocerebellar fibres pontine nuclei CPM is associated with: chronic alcoholism over-rapid correction of hyponatraemia There is no treatment. Click here for more information...

39. Central Pontine Myelinolysis Complete online version of The Encyclopaedia of Medical Imaging including textand images from The Encyclopaedia of Medical Imaging s eight book volumes http://www.amershamhealth.com/medcyclopaedia/medical/Volume VI 1/CENTRAL PONTINE

financial services our commitment our company Search Medcyclopaedia for: Search marked text (mark text before you click) Browse entry words starting with: A B C D ... amershamhealth.com Central pontine myelinolysis, (also called osmotic demyelination), demyelinating disorder found in alcoholics or in association with many systemic disorders with electrolyte abnormalities. Because of the common association with rapidly corrected hyponatraemia, the term "osmotic demyelination syndrome" has been proposed. The symptoms of central pontine myelinolysis are quadriparesis, pseudobulbar palsy and changing levels of consciousness, including coma and death. Histologically, the area of myelin breakdown is sharply demarcated and displays extensive loss of oligodendrocytes, infiltration with foamy macrophages and reactive astrocytosis. At MR the lesion is characterized by T2 hyperintensity in a central pontine location ( Fig.1 ); gadolinium enhancement may sometimes be present. Extrapontine sites of myelinolysis in the basal ganglia and midbrain, and subcortical white matter may also occur. Many entities can be considered in the differential diagnosis, including ischaemia, multiple sclerosis, encephalitis, toxic exposures, radiation therapy effects and brain stem gliomas. When present, the key to the MRI diagnosis is the bilateral involvement of the deep and capsular white matter, often accompanied by abnormalities in the thalami and basal ganglia.

40. Central Pontine Myelinolysis In A Previously Healthy 4-Year-Old Child With Acute central pontine myelinolysis (CPM) is rare, with fewer than 30 cases reported in CPM, central pontine myelinolysis. MRI, magnetic resonance imaging. http://pediatrics.aappublications.org/cgi/content/full/99/5/738

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Extract Full Text (PDF) P ... Citation Map Services E-mail this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Gregorio, L. Articles by Lee, D. A. Related Collections PEDIATRICS Vol. 99 No. 5 May 1997, pp. 738-742 EXPERIENCE AND REASON: Central Pontine Myelinolysis in a Previously Healthy 4-Year-Old Child With Acute Rotavirus Gastroenteritis INTRODUCTION Top Introduction Case Report Discussion References Acute gastroenteritis is one of the most common childhood illnesses encountered today. Vomiting and diarrhea often cause dehydration. Although the disease is usually self-limiting, patients may require rehydration therapy. Central pontine myelinolysis (CPM) is rare, with fewer than 30 cases reported in children. First described in 1959, it is a demyelinating process that affects the central pons and may involve other white matter areas. CPM presents with an altered

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