61. Search Result For "Canavan Disease" canavan disease; canavan disease; canavan disease; canavan disease; canavan disease Information Page; Screening The First Line in Prevention; http://www.noah-health.org/search/results.php?lang=1&keyword=Canavan Disease&dty

62. Canavan Disease - Brochures - BCM Medical Genetics Laboratories canavan disease is a genetic disorder that occurs most frequently in people of Ashkenazi canavan disease mainly affects the central nervous system. http://www.bcmgeneticlabs.org/brochures/lit docs/lit-canavan.html

Close Window Canavan Disease How does a person get Canavan disease? Canavan disease is a genetic disorder that is inherited from one's parents. As a result, a child must be born with Canavan to have it. It cannot be caught like a virus. Genes, the units of inheritance How is Canavan disease inherited? One in 40 people of Ashkenazi Jewish descent carry one mutation for Canavan disease. The mutation prevents the gene from working. These individuals are known as carriers and show no symptoms of the disease. They are perfectly healthy because they have another functional gene that can make aspartocyclase. Therefore, they are normal. In order for a child to have Canavan disease, both parents must be carriers of a Canavan mutation and pass the mutation on to their child. Therefore, a person with Canavan disease has two Canavan mutations, unlike their carrier parents who have only one. This pattern of inheritance is called autosomal recessive inheritance. Autosomal recessive inheritance For a couple in which both partners are Canavan disease carriers, in every pregnancy there is a 25% chance (1 in 4) of having a child with Canavan disease (the chance that each parent will pass on their Canavan gene is 1 in 2, or 1/2, so the chance that the child will receive both genes is 1/2 x 1/2, which is 1 in 4). There is also a 50% chance (1 in 2) of having a child who will be a healthy carrier like his/her parents. And there is a 25% chance of having a child who does not carry the Canavan gene at all.

63. Canavan Disease canavan disease. What is canavan disease? canavan disease, one of the most common cerebral degenerative diseases of infancy, is a genelinked, http://www.clevelandclinic.org/health/health-info/docs/1200/1259.asp?index=6013&

64. Canavan Disease This Web resource on canavan disease (a rare, inherited, A description of canavan disease is provided and available treatments, prognosis, http://omni.ac.uk/browse/mesh/D017825.html

low graphics Canavan Disease Canavan Disease Canavan Disease / genetics other: Cockayne Syndrome Hepatolenticular Degeneration Hereditary Central Nervous System Demyelinating Diseases Huntington Disease ... Tuberous Sclerosis Canavan Disease NINDS : Canavan disease information page This Web resource on Canavan disease (a rare, inherited, neurological disorder) is produced by the National Institute of Neurological Disorders and Stroke (NINDS). A description of Canavan disease is provided and available treatments, prognosis, and current research activities are all discussed. Links to related organisations are provided. This resource has a US focus. Patient Education Handout [Publication Type] Infant Child Canavan Disease Canavan Disease / genetics GeneReviews : Canavan disease Notes for physicians on Canavan disease (aspartoacylase deficiency, aspa deficiency). This document includes diagnosis, a clinical description, differential diagnosis, management, genetic counselling, and molecular genetics. Posted in September 1999 (updated November 2003), this resource forms part of GeneReviews (formerly GeneClinics profile), a peer-reviewed clinical genetic information resource that is funded by the US National Institutes of Health (NIH) and produced by the University of Washington, Seattle. This resource contains a summary and bibliographical references of the review. Canavan Disease / genetics Last modified: 02 Sep 2005

65. Canavan Disease --  Britannica Student Encyclopedia canavan disease a fatal genetic disorder that strikes infants. It has a relatively higher incidence among descendants of Eastern and Middle European Jews. http://www.britannica.com/ebi/article-9318598

Home Browse Newsletters Store ... Subscribe Already a member? Log in This Article's Table of Contents Canavan disease Print this Table of Contents Shopping Price: USD $1495 Revised, updated, and still unrivaled. The Official Scrabble Players Dictionary (Hardcover) Price: USD $15.95 The Scrabble player's bible on sale! Save 30%. Merriam-Webster's Collegiate Dictionary Price: USD $19.95 Save big on America's best-selling dictionary. Discounted 38%! More Britannica products Canavan disease  Student Encyclopedia Article Page 1 of 1 var mm = [["Jan.","January"],["Feb.","February"],["Mar.","March"],["Apr.","April"],["May","May"],["June","June"],["July","July"],["Aug.","August"],["Sept.","September"],["Oct.","October"],["Nov.","November"],["Dec.","December"]]; To cite this page: MLA style: "Canavan disease." Britannica Student Encyclopedia http://www.britannica.com/ebi/article-9318598 APA style: Canavan disease. ( Britannica Student Encyclopedia . Retrieved http://www.britannica.com/ebi/article-9318598

66. CANAVAN DISEASE canavan disease. The Canavan Research Foundation. Fairwood Professional Building. New Fairfield, CT 06812. (203) 7462436. (203) 746-3205 (fax) http://www.as.wvu.edu/~scidis/organizationC_D.html

CANAVAN DISEASE The Canavan Research Foundation Fairwood Professional Building New Fairfield, CT 06812 (203) 746-3205 (fax) canavanresearch @aol.com http://www.canavan.org/ CANCER American Cancer Society 1599 Clifton Rd. NE Atlanta, GA 30329-4251 (404) 982-3676 (fax) http://www.cancer.org Canadian Cancer Society 10 Alcorn Ave., Ste. 200 CAN M4V 3B1 Toronto, ON (416) 961-4189 (fax) ccs@cancer.ca http://www.cancer.ca Candlelighters Childhood Cancer Foundation 3910 Warner St. Kensington, MD 20895 (301) 962-3520 (phone/fax) info@candlelighters.org http://www.candlelighters.org Childhood Cancer Foundation-Candlelighters Canada 55 Eglinton Ave E, Ste. 401 CAN M4P 1G8 Toronto, ON (800) 363-1062 (Canada only) (416) 489-9812 (fax) staff@candlelighters.ca http://www.candlelighters.ca -Turcot Syndrome CELIAC DISEASE Canadian Celiac Association 5170 Dixie Rd, Ste 204 CAN L4W 1E3 Mississauga, ON (800) 363-7296 (Canada only) (905) 507-4673 (fax) celiac@look.ca http://www.celiac.ca Celiac Disease Foundation 13251 Ventura Blvd. #1 Studio City Los Angeles, CA 91604-1838 (818) 990-2379 (fax) cdf@celiac.org

67. Canavan Disease - St. Joseph Mercy, Ann Arbor Michigan canavan disease St. Joseph Mercy Health System Hospitals serving Ann Arbor, SE Michigan, Washtenaw County, Livingston County, Wayne County, Oakland County http://www.sjmercyhealth.org/12876.cfm

@import url(default.css); Online Health Information Health Information - Rare Diseases and Disorders Back to Health Library Print This Page Email to a Friend National Organization for Rare Disorders, Inc. Canavan Disease Synonyms Disorder Subdivisions General Discussion Resources ... For a Complete Report Important It is possible that the main title of the report Canavan Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms ACY2 Deficiency Aminoacylase-2 Deficiency Aspartoacylase Deficiency Canavan's Leukodystrophy Canavan-Van Bogaert-Bertrand Disease CD Spongy Degeneration of the Central Nervous System Spongy Degeneration of the Neuroaxis Van Bogaert-Bertrand Syndrome ASP Deficiency ASPA Deficiency Disorder Subdivisions None General Discussion Canavan disease is a rare inherited neurological disorder characterized by spongy degeneration of the brain and spinal cord (central nervous system). Physician symptoms that appear in early infancy may include progressive mental decline accompanied by the loss of muscle tone, poor head control, an abnormally large head (macrocephaly), and/ or irritability. Physical symptoms appear in early infancy and usually progress rapidly. Canavan disease is caused by an abnormality in the ASPA gene that leads to a deficiency of the enzyme aspartoacylase. Canavan disease is inherited as an autosomal recessive genetic disorder. Resources Kennedy Krieger Institute

68. Canavan Disease canavan disease is a rare, autosomal recessive inherited, The symptoms of canavan disease appear in early infancy and progress rapidly. http://www.thedoctorsdoctor.com/diseases/canavan_disease.htm

Background Canavan disease is a rare, autosomal recessive inherited, neurological disorder, classified as a leukodystrophy. The underlying genetic defect is an enzyme defect of aspartoacyclase. This enzyme normally breaks down N-acetylaspartate acid, or NAA, into the building blocks of myelin, the fatty membrane that surrounds nerves. With loss of this enzyme, the NAA builds up in the cells, impairing the normal function of the nervous system. With time, the brain has a characteristic spongy degeneration. The symptoms of Canavan disease appear in early infancy and progress rapidly. These symptoms include mental retardation, feeding difficulties, abnormal muscle tone, poor head control, and abnormally enlarged head. With time, paralysis, blindness, or hearing loss may occur. OUTLINE Epidemiology Pathogenesis Laboratory/Radiologic/Other Diagnostic Testing Gross Appearance and Clinical Variants ... Internet Links EPIDEMIOLOGY CHARACTERIZATION SYNONYMS Van Bogaert-Bertrand INCIDENCE Very rare AGE RANGE-MEDIAN Birth GEOGRAPHY Eastern European Jewish Canavan disease prenatal diagnosis and genetic counseling.

69. Canavan Disease -- Facts, Info, And Encyclopedia Article canavan disease, also known as Van BogaertBertrand disease is a rare, It was first described by Myrtelle Canavan in 1931. canavan disease is one of a http://www.absoluteastronomy.com/encyclopedia/c/ca/canavan_disease.htm

Canavan disease [Categories: Genetic disorders, Eponymous diseases] Canavan disease , also known as Van Bogaert-Bertrand disease is a rare, inherited, (A disorder of the nervous system) neurological disorder characterized by spongy degeneration of the (That part of the central nervous system that includes all the higher nervous centers; enclosed within the skull; continuous with the spinal cord) brain (in which the (Whitish nervous tissue of the CNS consisting of neurons and their myelin sheaths) white matter is replaced by microscopic fluid-filled spaces). It was first described by Myrtelle Canavan in 1931. Canavan disease is one of a group of (A disease or disorder that is inherited genetically) genetic disorder s called the leukodystrophies that affect growth of the (A white fatty substance that forms a medullary sheath around the axis cylinder of some nerve fibers) myelin sheath of the (A threadlike extension of a nerve cell) nerve fiber s in the brain. Although Canavan disease may occur in any ethnic group, it affects persons of (Click link for more info and facts about Eastern Europe) Eastern Europe an (A person belonging to the worldwide group claiming descent from Jacob (or converted to it) and connected by cultural or religious ties) Jew ish ancestry more frequently. About 1/40 individuals of

70. MedlinePlus Medical Encyclopedia: Canavan Disease canavan disease is an inherited disorder of aspartic acid metabolism. canavan disease is inherited as an autosomal recessive trait. http://www.nlm.nih.gov/medlineplus/ency/article/001586.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Canavan disease Contents of this page: Alternative names Definition Causes, incidence, and risk factors Symptoms ... Prevention Alternative names Spongy degeneration of the brain; Aspartoacylase deficiency Definition Return to top Canavan disease is an inherited disorder of aspartic acid metabolism. It is characterized by degeneration of the white matter of the brain Causes, incidence, and risk factors Return to top Canavan disease is inherited as an autosomal recessive trait. It is more common among Ashkenazi Jews than in the general population. A deficient enzyme , aspartoacylase, results in the accumulation of N-acetylaspartic acid in the brain. This causes a degeneration of the white matter. Typically, symptoms begin in the first year of life. Parents tend to notice when a child is not reaching particular developmental milestones, including poor muscle tone and lack of head control. Eventually, the child can develop feeding problems, seizures, and loss of vision. Although death often occurs before 18 months of age, some live until they are teenagers or, rarely, young adults.

71. BrainTalk Communities - Canavan Disease Reload this Page canavan disease. User Name, Remember Me? Password Threads in Forum canavan disease, Forum Tools, Search this Forum. Announcement http://brain.hastypastry.net/forums/forumdisplay.php?f=102

72. BrainTalk Communities - Canavan Disease Online patient support groups for healthcare and neurology. http://brain.hastypastry.net/forums/archive/index.php/f-102.html

BrainTalk Communities Specific Neurological Conditions (A - L) PDA View Full Version : Canavan Disease Helpful websites Useful Websites

73. Health Care Information Resources Canavan Disease Links canavan disease Links. For more information, see Genetic conditions, canavan disease Canavan Foundation canavan disease often attacks children in http://www-hsl.mcmaster.ca/tomflem/canavan.html

The address of this page is: http://hsl.mcmaster.ca/tomflem/canavan.html Canavan Disease Links For more information, see: Genetic conditions , also in the Illness section of this resource. For more information, see: Leukodystrophies , also in the Illness section of this resource. Canavan disease - Canavan Foundation Canavan disease often attacks children in Ashkenazi Jewish families Canavan disease - Canavan Disease from the University of Pittsburgh Department of Human Genetics Canavan disease - Canavan Research Fund Canavan disease - Canavan Disease Canavan disease - Canavan Research Illinois raising awareness, supporting research and networking Please read

74. Hill Health Topics A-Z - Canavan Disease canavan disease. National Organization for Rare Disorders. Important It is possible that the main title of the report canavan disease is not the name you http://www.healthwise.net/hillhealth/Content/StdDocument.aspx?DOCHWID=nord157&SE

75. Rare Pediatric Disease Database WHAT canavan disease is a rare, inherited, degenerative brain disorder that WHO canavan disease is inherited in an autosomal recessive fashion meaning http://www.madisonsfoundation.org/content/3/1/display.asp?did=389

76. Canavan Disease canavan disease. Canavan Foundation canavan disease Canavan Research Foundation dedicated to finding a cure by raising funds for medical research. http://www.ability.org.uk/Canavan_Disease.html

Our Aims Services Stats ... Z Canavan Disease Canavan Foundation Canavan Disease Canavan Research Foundation - dedicated to finding a cure by raising funds for medical research. Canavan Foundation What Every Family Should Know Webmaster . Site Design by Ability "see the ability, not the disability" Acknowledgments

77. Canavan Disease canavan disease. Aminoacylase 2 deficiency. Aspartoacylase deficiency Images in a 17month-old child with canavan disease Images in a 17-month-old http://www.gfmer.ch/genetic_diseases_v2/gendis_detail_list.php?cat3=525

78. Jacob's Ladder canavan disease. What is canavan disease? canavan disease is an inherited, progressive neurodegenerative disease which strikes in early infancy causing http://www.jacobsladder.ca/canavan.html

Canavan Disease What is Canavan Disease? Canavan disease is an inherited, progressive neurodegenerative disease which strikes in early infancy causing progressive mental and physical disabilities. Children with Canavan disease have limited ability to move their hands, hold their head up, or perform even the simplest of tasks. Over a period of time, these children may even lose their sense of sight and the ability to swallow food. Unfortunately, children afflicted with Canavan disease are unable to sit, crawl, walk, or even speak. Although Canavan disease is rare, it is but one form of a group of disorders called leukodystrophies, in which a greater number of children are also affected by structural abnormalities and deterioration of motor, sensory, and intellectual functions. Children with Canavan disease are unable to produce an enzyme called aspartoacylase. As a result, abnormal fluid collections develop in parts of the brain, particularly in the white matter. The result is a distinctive microscopic change called spongy degeneration which produces the progressive neurological symptoms of Canavan disease. What Characterizes Leukodystrophies?

79. Supplement Could Hold Key To Canavan Disease Supplement could hold key to canavan disease Acetate supplementation could prove to be an effective therapy for canavan disease, a rare congenital brain http://www.nutraingredients-usa.com/news/news-ng.asp?id=60268-supplement-could-h

80. Canavan Disease - Information And Support Resources canavan disease Overview, Screening, Testing, and Support Resources. http://www.mazornet.com/genetics/canavan.asp

Jewish Genetic Diseases A Mazornet Guide VISIT MazorNet's other Jewish Guides The MazorNet-Jewish Celebrations Kosher Restaurant Guide The MazorNet- Jewish Celebrations Vendor Directory ( ... Photographers, Kosher Caterers, Bridal Gowns, and Much More) Important Information Home Page Genetic Counseling and Screening Genetic Screening Laboratories - A Directory A Brief Key to Basic Genetic ... s Select Disorder Bloom's Syndrome Breast and Ovarian Cancers Breast Cancers - Prevention and Resources Canavan Disease ... Ulcerative Colitis Recommended Reeading Genetic Diversity Among Jews - Diseases and Markers at the DNA Level Provides an authoritative, up-to-date account of the impact of molecular genetics on our understanding of genetic diseases prevalent among Jews. Jewish Genetic Disorders : A Layman's Guide Guide to genetic disorders that tend to affect the Jewish population more than the non-Jewish, including a short history of the Jews and basic facts concerning genetics and genetic disorders. Interactive Jewish Genetic Diseases Boards Canavan Disease Canavan is an inherited disease which is due to lack of substance in the body called aspartoacylase (ASPA). It is a type of enzyme normally found in the part of the brain where nerve impulses are sent to other parts of the brain and the spinal cord. ASPA breaks down NAA into 2 smaller compounds. When ASPA is missing NAA builds up and causes brain damage, mental retardation, large head size tremors and inability to move muscles

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 4     61-80 of 104    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20