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         Beryllium Disease:     more detail
  1. Chronic beryllium disease and sensitization at a beryllium processing facility.(Research/ Environmental Medicine): An article from: Environmental Health Perspectives by Kenneth Rosenman, Vicki Hertzberg, et all 2005-10-01
  2. Beryllium Disease: A Summary of the Occupational Health Concern by Renzo Bertolini, 1989
  3. ANALYSES OF FACTORS IN BERYLLIUM ASSOCIATED DISEASES by M.D. John F. Zielinski, 1962
  4. Managing Health Effects of Beryllium Exposure by Committee on Beryllium Alloy Exposures, Committee on Toxicology, et all 2008-09-30
  5. Report on the beryllium problem: As discussed at the sixth Saranac Symposium, Saranac Lake, N.Y., 27 September to 3 October, 1947 by W. E Park, 1947
  6. Beryllium toxicity (Case studies in environmental medicine) by Dennis M Green, 1997

61. Beryllium Symposium
Immunopathology of BerylliumInduced Granulomatous Disease Chronic beryllium disease (CBD) is a lung disease similar clinically to other granulomatous
http://www.ornl.gov/sci/techresources/meetings/beryllium/session1.shtml
Beryllium Research Symposium: Basic Mechanisms and Human Health
June 25- 26, 2002
National Library of Medicine
, Bethesda, MD
Contents Introduction Welcome Agenda ... Attendees Sponsored by
Office of Biological and Environmental Research

The Department of Energy
in cooperation with
The National Institute for Occupational Safety and Health, and
The National Jewish Medical and Research Center
Session 1. Immunopathology of Beryllium-Induced Granulomatous Disease
Characterization of Beryllium-Specific Memory CD4+ T Cells in Patients with Chronic Beryllium Disease Andrew P. Fontenot , Scott J. Canavera, Laia Gharavi, Lee S. Newman, and Brian L. Kotzin
University of Colorado Health Sciences Center and National Jewish Medical and Research Center, Denver, CO 80262
andrew.fontenot@uchsc.edu Evidence suggest that CD4+ T cells play a critical role in the development of chronic beryllium disease (CBD). Using intracellular cytokine staining, we found that the frequency of beryllium-specific CD4+ T cells in the lungs of 10 CBD patients ranged from 1.4-29% (mean 18.8%), and these T cells expressed a Th1-type phenotype in response to beryllium sulfate (BeSO ). Few, if any, beryllium-specific CD8+ T cells were identified. In contrast, the frequency of beryllium-responsive CD4+ T cells in the blood of these subjects ranged from undetectable to 1 in 500. No correlation was observed between the frequency of beryllium-responsive BAL CD4+ T cells detected with intracellular cytokine staining and lymphocyte proliferation in culture after BeSO

62. Toxics Law Reporter - Plant Worker With Beryllium-Related Disease
Beryllium Plant Worker With BerylliumRelated Disease beryllium and chronic beryllium disease and asked him to participate in a beryllium worker study
http://subscript.bna.com/SAMPLES/txlr.nsf/0/a7d062531b33b82c85256fd4007800a8?Ope

63. Beryllium Central Jon Gelman Attorney 1-888-696-7900
beryllium disease benefits for energy workers and their families, bystanders and household contact. Medical and legal resources.
http://www.berylliumcentral.com/
Beryllium Central
Beryllium Disease Resouces
What Is The Federal Cold War Compensation Act
Medical Resources for Beryllium Related Disease Who Was Exposed Where Beryllium Was Used ... What's New Beryllium
Beryllium Central Cold War Compensation Medical Resources Who Is At Risk ... Reading Room
Jon Gelman, who practices in Wayne, NJ , wrote Workers' Compensation Law, 3rd ed. (West Group). He can be reached electronically at: jon@gelmans.com . Internet: www.gelmans.com ; 1450 Valley Road, PO Box 934, Wayne, NJ 07474-0934, Toll Free: (888) 696-7900, Tel: (973) 696-7900; Fax: (973) 696-7988.
For additional information call Toll Free 1(888) 696-7900 Subscribe to
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64. Policy Analysis And Clinical Research On Occupational Beryllium Exposure At DOE
Investigating Chronic beryllium disease prevalence among former Chronic beryllium disease (CBD) involves the ongoing stimulation of the immune system
http://www.cresp.org/dcwrkshp/posters/be/be.html
Consortium for Risk Evaluation with Stakeholder Participation
Policy Analysis and Clinical Research on Occupational Beryllium Exposure at DOE Sites
R A Ponce
T K Takaro
S M Bartell
A J Jabbour
K Ertell
J Abbotts
S Barnhart
and E M Faustman
Worker Safety and CRESP and School of Public Health and Community Medicine, University of Washington, Seattle, WA
This research supported in part by CRESP through the Department of Energy Cooperative Agreement #DE-FC01-95EW55084. This support does not constitute endorsement of views expressed.
Introduction
The US Department of Energy has used beryllium in nuclear materials production, reactor rod fabrication, nuclear vessel cladding and many other uses since the 1940s. The industrial use of beryllium was found to result in an acute respiratory disease, acute beryllium disease, leading the Atomic Energy Commission to establish an airborne concentration standard of 2 µg/m3 for the workplace based on then accepted standards for other metals. Adoption of this standard has effectively eliminated the presence of acute beryllium disease. However, epidemiologic studies carried out during the 1980-90s has revealed the presence of another form of lung disease, chronic beryllium disease (CBD), among workers at US DOE sites. In 1997, the Consortium for Risk Evaluation with Stakeholder Participation (CRESP) began a series of research efforts to investigate the prevalence of CBD among former beryllium workers at Hanford, evaluation of alternatives to the current screening tools for identifying pre-clinical disease, and policy implications of alternative occupational health program designs to reduce disease incidence among future beryllium workers, such as those involved in decontamination and decommissioning former beryllium facilities.

65. Log In Problems
Beryllium Sensitization May Progress to Chronic beryllium disease CME. News Author Laurie Barclay, MD CME Author Désirée Lie, MD, MSEd Disclosures
http://www.medscape.com/viewarticle/497063
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66. Chronic Beryllium Disease Prevention Program-Provides Information And Resources
This web site locates thousands of US Government science and technology resources on the web that let you tap into government expertise, services,
http://www.scitechresources.gov/Results/show_result.php?rec=1280

67. Major Histocompatibility Locus Genetic Markers Of Beryllium Sensitization And Di
HLADPB1 and Chronic beryllium disease A HuGE Review Am. J. Epidemiol., March 1, 2003; 157(5) 388 - 398. Abstract Full Text PDF
http://erj.ersjournals.com/cgi/content/abstract/18/4/677
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ISI Web of Science (18)
PubMed PubMed Citation Articles by Saltini, C. Articles by Tinelli, C. Eur Respir J 2001; 18:677-684
ERS Journals Ltd
Major histocompatibility locus genetic markers of beryllium sensitization and disease C. Saltini L. Richeldi M. Losi M. Amicosante C. Voorter E. van den Berg-Loonen R.A. Dweik H.P. Wiedemann D.C. Deubner and C. Tinelli Division of Respiratory Diseases of the University of Rome "Tor Vergata" at the National Institute for Infectious Diseases (INMI), Spallanzani Hospital, Rome, Italy. Division of Pneumology, Policlinico, Modena, Italy. Laboratory of Clinical Pathology, INMI, Spallanzani Hospital, and the Dept of Cell Biology, University of "Tor Vergata", Rome, Italy.

68. Berylliosis
(beryllium disease). by Rick Alan. Definition. Berylliosis is an occupational lung disease. It occurs in people who work with beryllium.
http://healthgate.partners.org/browsing/browseContent.asp?fileName=22480.xml&tit

69. Chronic Beryllium Disease - Information & News
Researchers at National Jewish Medical and Research Center have developed a method for finding the molecular targets of the immune system,
http://www.news-medical.net/?keyword=Chronic beryllium disease

70. Medical News: Beryllium Disease May Not Become Evident For 40 Years - WrongDiagn
Medical news summary describing beryllium disease may not become evident for 40 years in relation to symptoms, diagnosis, misdiagnosis and treatment.
http://www.wrongdiagnosis.com/news/beryllium_disease_may_not_become_evident_for_
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Medical News Summary: Beryllium disease may not become evident for 40 years
About: Beryllium disease may not become evident for 40 years Date: 7 November 2004 Source: Bradenton Author: Donna Wright Medical News Summary (summary of medical news story as reported by Bradenton): Concerns are rising about the number of people potentially affected by beryllium disease. At the time, there were no safety standards for working in a beryllium plant and many people may have been directly or indirectly exposed to it. Even wives washing uniforms may have come into contact. Beryllium is a carcinogen. Symptoms of beryllium poisoning may not become evident for 40 years, beryllium sensitivity and chronic beryllium disease include shortness of breath, sudden weight loss, tiredness, skin problems and night sweats. Treatment can be effective if the disease is diagnosed early enough. URL: http://www.bradenton.com/mld/bradenton/news/local/10119651.htm

71. Chronic Beryllium Disease (berylliosis)
berylliosis – Cleveland Clinic Pulmonary, Allergy Critical Care – leaders in the diagnosis and treatment of pulmonary, respiratory and allergic
http://cms.clevelandclinic.org/ccfpulmonary/body.cfm?id=51

72. Rates Of Beryllium Disease On The Rise
beryllium disease slowly destroys the lungs after the dust is inhaled. Risks of beryllium disease related to work processes at a metal alloy and oxide
http://www.biomed.lib.umn.edu/hmed/1999/03/19990329_ber.html
HMED Home About HMED
View abstracts from: Search all years
Health and Medicine in the News
Headline:
Beryllium dangers were kept secret
Newspaper Article Synopsis:
A recent investigation into the safety practices at a beryllium plant in Ohio has found that federal officials knew of the risks to workers but did little rectify the situation. Beryllium disease slowly destroys the lungs after the dust is inhaled.
Newspaper Article Source:
Toledo Blade. Beryllium dangers were kept secret. Star Tribune, 1999 March 29: A4(col. 1-4).
Journal Article Citation:
Kreiss K., et al. Risks of beryllium disease related to work processes at a metal alloy and oxide production plant. Occupational and Environmental Medicine 1997 Aug; 54. lam /03/30/1999 MNCAT BioMedSearch MEDLINE Library Instruction ... BIS Bio-Medical Library
Diehl Hall
University of Minnesota
Minneapolis, MN 55455-0334 Twin Cities
Telephone:(612)626-5653
FAX: (612)626-2454
Email: medref@umn.edu University of Minnesota University Libraries
Last revised: Aug 21, 2003
URL of this page: http://www.biomed.lib.umn.edu/hmed/1999/03/19990329_ber.html

73. Seminar At WVU To Focus On Chronic Beryllium Disease
Exposure to beryllium in the workplace may lead to various diseases including However? even a family member can develop chronic beryllium disease from
http://www.nis.wvu.edu/2002_Releases/BeryilliumDisease.htm
News and Information Services
News Release Back to Newsroom Friday August 30, 2002 Seminar at WVU to focus on Chronic Beryllium Disease CONTACT: Ainsley Weston , NIOSH CDC, 304-285-6221 A toxicologist from the National Institute for Occupational Safety and Health (NIOSH) Centers for Disease Control and Prevention will speak on "Genetic Factors in Chronic Beryllium Disease" at 3:30 p.m. Tuesday, Sept. 3, in Room 2001 of the Agricultural Sciences Building, Evansdale Campus. Ainsely Weston will give the next presentation in a seminar series organized by West Virginia University’s interdisciplinary program in Genetics and Developmental Biology. A strong, lightweight, alkaline earth element with a high melting point, beryllium has been used most successfully in components of nuclear reactors‚ nuclear weapons, aircraft and spacecraft. Beryllium compounds are used in ceramics for electronics, in dental bridges and in some sports equipment. Exposure to beryllium in the workplace may lead to various diseases including chronic beryllium disease, which causes a painful scarring of the lung tissue. Workers in certain occupations and industries are most likely to develop the disease. However‚ even a family member can develop chronic beryllium disease from exposure to dust on the worker’s clothing‚ hair or body.

74. Chronic Beryllium Disease Dust Exposure Attorneys Berkeley California Law Firm
The California lawyers at Paul, Hanley Harley represent victims and families in Beryllium and other beryllium related cases throughout the country.
http://www.phhlaw.com/PracticeAreas/PracticeAreaDescriptions19.asp
Thursday, September 8, 2005
Please contact us today by phone or e-mail us a question.
Message:
Office Locations:
Northern California

1608 Fourth Street,
Suite 300
Berkeley, CA 94710
Phone: (510) 559-9980
Fax: (510) 559-9970
Southern California 5716 Corsa Ave, Suite 203 Westlake Village, CA 91362 Phone: (818) 865-2807 Fax: (818) 865-0805 811 W. Seventh St. Suite 206 Los Angeles, CA 90017 Phone: (213) 689-3278 Fax: (213) 689-4309 Chronic Beryllium Disease is an incurable lung disease caused by the inhalation of beryllium dust and fumes. Some of the symptoms of Chronic Beryllium Disease are cough, shortness of breath, fatigue, weight loss, loss of appetite, fever, and night sweats. The use of steroids is the primary way to control the progression of this disease. Supplemental oxygen may be needed for some individuals. A lung transplant may be the last alternative for some. There is a special test, that can be done to see if you are sensitized to beryllium. This test is called a beryllium lymphocyte proliferation transformation test. It is typically a blood test, but it can also be done through a lung washing. X-rays may be helpful to see if there is any scarring of the lungs caused by the inhalation of beryllium dust or fumes. A special type of scarring of the lungs called granuloma may be found in lung biopsy tissue. Pulmonary function tests can show if there are abnormalities in the breathing functions of the lungs. Sometimes beryllium disease is misdiagnosed as sarcoidosis, but a lymphocyte transformation test and a history of exposure to beryllium can differentiate these diseases.

75. Community Meeting On Beryllium Disease -- Ohio Citizen Action
Community meeting on beryllium disease, with Dr. Kathleen Fagan, occupational health specialist and expert on beryllium and toxic exposures
http://www.ohiocitizen.org/campaigns/brush/genoa_mtg.html
Community meeting on beryllium disease, with Dr. Kathleen Fagan, occupational health specialist and expert on beryllium and toxic exposures
  • What are the dangers of living, working, or going to school near a beryllium plant? How do people contract beryllium disease? Why is diagnosing beryllium disease in the community difficult? What can we do to minimize or eliminate the risks of beryllium exposure in the community?
What:
Please attend this important community meeting to learn more about this deadly disease and discuss ways to stop it. Who:
Dr. Kathleen Fagan will join us to discuss the dangers of living near a beryllium plant and beryllium disease. Dr. Fagan is a occupational medicine specialist, trained in work related toxic exposures and recognized by National Institute of Occupational Safety and Health as a beryllium expert. This meeting is open to the public. When:
Tuesday, January 15, 2002 6:30 pm Where:
Genoa public library 602 West St. (on the corner of West St. and W 6th St.) For more information:
Please contact Amy Ryder , toll-free (888) 777-7135.

76. Resources For Dental Professionals -- Ohio Citizen Action
You don’t have to be a beryllium worker to get beryllium disease. Anybody exposed to beryllium dust or fumes can get it. Some contract workers at beryllium
http://www.ohiocitizen.org/campaigns/brush/dentalresource.html
Resources for dental professionals:
Beryllium in the dental industry
You don’t have to be a beryllium worker to get beryllium disease. Anybody exposed to beryllium dust or fumes can get it. Some contract workers at beryllium plants, automotive manufacture workers and dental lab technicians have developed beryllium disease. All dental professionals exposed to beryllium dust or fumes, especially lab technicians, can get this disease. The best way to eliminate the risk is to stop using beryllium. The following resources may help you decide whether you or your staff are in danger of beryllium disease.

77. Session Beryllium Exposure And Disease In Populations Downstream
848 AM, Screening for beryllium disease among construction trade workers at 924 AM, Cumulative incidence of chronic beryllium disease in a ceramics
http://apha.confex.com/apha/131am/techprogram/session_11742.htm
5060.0: Wednesday, November 19, 2003: 8:30 AM-10:00 AM Oral Beryllium Exposure and Disease in Populations Downstream from Production: Nuclear Weapons Workers and the Public Surrounding Production Plants Learning Objectives: At the conclusion of this session, the participant will be able to (1) identify high risk populations for beryllium disease in nuclear weapons and clean-up workers; (2) understand important aspects of the beryllium exposure/response relationship of proven relevance to occupational health with potential application to community-based exposures; (3) evaluate the adequacy of current monitoring and beryllium disease prevention programs. See individual abstracts for presenting author's disclosure statement and author's information. Organizer(s): Tim Takaro, MD, MPH 8:30 AM Beryllium exposure and disease in populations downstream from production: Nuclear weapons workers and the public surrounding production plants
Tim Takaro, MD,, MPH 8:48 AM Screening for beryllium disease among construction trade workers at department of energy nuclear sites.
Laura Welch, MD, Knut Ringen, PhD

78. Nat'l Academies Discovery Engine
A Genetic Marker for Chronic beryllium disease, pp. 293303 read skim srch • Immunology of Chronic beryllium disease, pp. 304-312 read skim srch
http://lab.nap.edu/nap-cgi/discover.cgi?term=beryllium disease&restric=NAP&

79. Los Alamos National Laboratory (LANL): New Los Alamos Tests Will Aid Beryllium W
If we re interested in preventing beryllium disease, we have to consider all the DOE has established its Chronic beryllium disease Prevention Program,
http://www.lanl.gov/news/index.php?fuseaction=home.story&story_id=981

80. - Toledoblade.com -
She died of beryllium disease, a lung illness that has affected scores of workers locally and nationwide. Government and industry records show that many of
http://www.toledoblade.com/apps/pbcs.dll/artikkel?Dato=19990328&Kategori=SRDEADL

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