41. Pharmacyclics.com - Brain Metastases Smart Clinical Trials, Motexafin Gadolinium Develops and markets chelated products for possible use in combination with existing therapies for cancer and atherosclerosis. Includes product pipeline, technology and investor details. Sunnyvale, California. (Nasdaq PCYC) http://www.pharmacyclics.com/

Pharmacyclics.com We conduct brain Metastases clinical trials, non small cell lung cancer treatment and smart trial using xcytrin and motexafin gadolinium. Pharmacyclics , Inc., was founded in 1991 based on the unique scientific collaboration between the company's co-founders, Jonathan L. Sessler, Ph.D. and company president and chief executive officer, Richard A. Miller, M.D. Dr. Sessler met Dr. Miller when his own cancer was being treated (and eventually cured) by Dr. Miller at Stanford University Medical Center in the early 1980s. Informal conversations between the two about how Sessler, who was at that time a graduate student in chemistry at Stanford, might apply his knowledge to create novel treatments for cancer led to more focused laboratory experiment and conducting brain metastases clinical trials . Based on interactions between the two over the next several years, Sessler and his colleagues developed the "texaphyrin" molecules, so named because they were discovered at the University of Texas, where Sessler was now working. Smart clinical trial is one of the ways the work goes forward. This work was first described in a landmark publication in the Proceedings of the National Academy of Sciences journal in 1996.Miller and Sessler formed Pharmacyclics, licensing the texaphyrin technology from the University of Texas. Also makes uses of

42. BioMed Central | Current Atherosclerosis Reports Current atherosclerosis Reports, Volume 7, Issue 4 (July 2005) more info.Access to the full text or PDF of articles from Current atherosclerosis Reports http://www.biomedcentral.com/curratherosclerrep/

home journals A-Z subject areas advanced search ... my BioMed Central Quick Search Current Atherosclerosis Reports BioMed Central PubMed Central PubMed Jump to article Current Atherosclerosis Reports Home Journal site Advanced search Archive About this journal ... Most viewed Current Atherosclerosis Reports, Volume 7, Issue 5 (September 2005) more info Access to the full text or PDF of articles from Current Atherosclerosis Reports requires a subscription to the journal. Abstracts are freely accessible. previous issue Invited Commentary Lipoprotein(a): Implications for Clinical Practice Robert C Block MD, Thomas A Pearson MD MPH PhD Current Atherosclerosis Reports September Abstract Full text PDF Trial Report Trial Report - Clinical Trials and Their Interpretations Peter P Toth MD PhD Current Atherosclerosis Reports September Abstract Full text PDF PubMed ... Related articles Reports New Insights in the Treatment of Dyslipid-emia: A Focus on Cardio-vascular Event Reduction and the Antiatherosclerotic Effects of Atorvastatin Peter P Toth MD PhD Current Atherosclerosis Reports September Abstract Full text PDF Hepatic High-Density Lipoprotein Receptors: Roles in Lipoprotein Metabolism and Potential for Therapeutic Modulation Bernardo L Trigatti PhD Current Atherosclerosis Reports September Abstract Full text PDF Statins and Proteinuria Donald G Vidt MD Current Atherosclerosis Reports September Abstract Full text PDF Evidence-based Management of Peripheral Vascular Disease Nicolas W Shammas MS MD, Eric J Dippel MD

43. Chemokine Therapeutics Is A Biotechnology Company With Expertise In Chemokine Ba Company involved in discovery, development, and manufacture of peptide analogs and peptidomimetics for the treatment of cancer, multiple sclerosis, arthritis, and atherosclerosis. Includes technical overview, profiles and contacts in Vancouver, Canada. http://www.chemokine.net/

var javascript_version = 1.0; Home Contact Corporate Profile Technology ... Media Chemokine Therapeutics Corp. discovers and develops peptide analogs of chemokines for cancer treatment, and immune system recovery. Chemokine Therapeutics Corp. is a publicly-held biotechnology company with expertise in chemokines-based drugs. Chemokine Therapeutics Publishes First Demonstration of . . . more Internationally recognized Stem Cell researcher Joins Chemokine's . . . more Chemokine Therapeutics Corporation announces Second Quarter . . . more OTCBB TSX CHKT / CTI / Chng: Chng: High: High: Low: Low: Vol: Vol: Charts indicate 1 mo period Today's Market Information Chinese Home Contact ... Sitemap

44. Atherosclerosis - Wikipedia, The Free Encyclopedia atherosclerosis is commonly referred to as a hardening or furring of blood atherosclerosis typically begins in later childhood, is usually found in http://en.wikipedia.org/wiki/Atherosclerosis

Wikimedia needs your help in the final days of its fund drive. See our fundraising page Over US$225,000 has been donated since the drive began on 19 August. Thank you for your generosity! Atherosclerosis From Wikipedia, the free encyclopedia. Atherosclerosis Atherosclerosis is a disease of arterial blood vessels or veins that have been surgically moved to function as an artery Athēra is porridge in Greek, as the plaque changes have a foamy appearance under high power light microscopy Sclerosis denotes hardening. Atherosclerosis is commonly referred to as a "hardening" or "furring" of blood vessels, but this is an oversimplification. Vascular lesions known as atheromas (or atheromata or atheromatous plaques ) develop in the vessel wall and in late stages may reduce or restrict blood flow in the lumen stenosis ), as well as rupturing and leading to downstream tissue damage. Contents Symptoms Atherogenesis Cellular Calcification and lipids ... edit Symptoms Atherosclerosis typically begins in later childhood, is usually found in most major arteries , yet is asymptomatic and not detected by most diagnostic methods during life. It most commonly becomes seriously symptomatic when interfering with the

45. GERON Discovers and develops therapeutic and diagnostic products, as well as projects for cancer, skin aging, atherosclerosis, osteoporosis and macular degeneration. Headquartered in Menlo Park, California. (Nasdaq GERN) http://www.geron.com/

September 6, 2005. GERON ANNOUNCES PUBLICATIONS DEMONSTRATING EFFICACY OF GRN163L, ITS PAN-CANCER DRUG, IN ANIMAL MODELS OF HUMAN LIVER AND LUNG CANCER September 6, 2005. GERON ANNOUNCES PUBLICATIONS DEMONSTRATING EFFICACY OF GRN163L, ITS PAN-CANCER DRUG, IN ANIMAL MODELS OF HUMAN LIVER AND LUNG CANCER

46. Atherosclerosis (arteriosclerosis - Hardening Of The Arteries) atherosclerosis refers to the build up of plaque in the walls of the arteriesleading to a reduction in the calibre of the vessel. http://www.netdoctor.co.uk/diseases/facts/atherosclerosis.htm

Search: All NetDoctor Diseases Medicines NetDoctor.co.uk Home News and features News News archive Newsletter Features Encyclopaedia Diseases Examinations Medicines Premium services SMS services StayQuit thediet Health centres ADHD Allergy and asthma Children's health Depression ... All health centres Discussion and support Discussion forums Support groups Services Ask the doctor Find a hospital Search Medline Test yourself Information About NetDoctor Commercial opportunities NetDoctor.com Atherosclerosis (arteriosclerosis - hardening of the arteries) Reviewed by Dr Neal Uren , consultant cardiologist What is atherosclerosis? Atherosclerosis refers to the build up of plaque in the walls of the arteries leading to a reduction in the calibre of the vessel. The narrowing does not occur suddenly but builds up over several years where cholesterol , fat and the smooth muscle cells lining the blood vessels have been transformed into a thickened, and sometimes calcified, mass. The result is that the arteries become constricted, their elasticity disappears and the volume of blood able to travel through them at any given time is reduced. What are the symptoms of atherosclerosis?

47. Home – Information About PLAVIX, An Antiplatelet Medication – Plavix Indicated for the reduction of atherosclerotic events (myocardial infarction, stroke and vascular death) in patients with atherosclerosis documented by recent stroke, recent myocardial infarction, or established peripheral arterial disease. http://www.plavix.com/

48. Atherosclerosis - General Practice Notebook Clinicallyoriented information. http://www.gpnotebook.co.uk/MedwebPage.cfm?ID=-657457151

49. THE MERCK MANUAL--SECOND HOME EDITION, Ch. 32, Atherosclerosis There are two main theories about why atherosclerosis develops High levels of Risk factors for atherosclerosis include smoking, high levels of http://www.merck.com/mmhe/sec03/ch032/ch032a.html

var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Heart and Blood Vessel Disorders Chapter Atherosclerosis Topics Atherosclerosis Atherosclerosis Buy The Book Print This Topic Email This Topic Pronunciations angina arterioles arteriolosclerosis arteriosclerosis ... triglycerides Atherosclerosis is a condition in which patchy deposits of fatty material (atheromas or atherosclerotic plaques) develop in the walls of medium-sized and large arteries, leading to reduced or blocked blood flow. Coronary Artery Disease: Introduction )) and strokes (due to atherosclerosis that affects the arteries to the brain (see Supplying the Brain With Blood )) are responsible for more deaths than all other causes combined.

50. Mayo Clinic Heart Resource Center Information about atherosclerosis, coronary artery disease, diagnostic tests, treatment, risk factors and prevention. http://www.mayoclinic.com/home?id=HQ00816

51. THE MERCK MANUAL, Sec. 16, Ch. 201, Arteriosclerosis The prevalence of clinical manifestations of atherosclerosis in general increases The earliest detectable lesion of atherosclerosis is the fatty streak http://www.merck.com/mrkshared/mmanual/section16/chapter201/201b.jsp

52. Howstuffworks "How Heart Disease Works" Carl Bianco M.D. provides a 6part graphical in-depth look at heart disease, heart attacks and angina. Topics include atherosclerosis, hypertension, cholesterol, smoking, obesity, diabetes mellitus and stress. http://www.howstuffworks.com/heart-attack.htm

TCDA("cc=hlt; dt"); Auto Stuff Science Stuff Health Stuff Entertainment Stuff ... Shop for Stuff Top Subjects Cholesterol Dieting Nicotine Sleep ... Tattoos Sponsored By: Subjects Diseases and Conditions Drugs Fitness Health Care ... Browse the Health Library Explore Stuff Lidrock.com Stuffo.com Big List of Articles Get the Newsletter ... Diseases and Conditions How Heart Disease Works by Carl Bianco, M.D. Table of Contents Introduction to How Heart Disease Works Coronary Artery Disease Are You at Risk? Angina Unstable Angina Heart Attack Treatment of MI Lots More Information Heart disease is the leading cause of death in the U.S. At some point in your life, either you or one of your loved ones will be forced to make decisions about some aspect of heart disease. Knowing something about the anatomy and functioning of the heart, in particular how angina and heart attacks work, will enable you to make informed decisions about your health. Heart disease can strike suddenly and require you to make decisions quickly. Being informed prior to an emergency is a valuable asset to you and your family. In this article we will discuss various heart diseases and how they can lead to a heart attack, or even a stroke. We will also look at how heart attacks are treated and what you should do to prevent heart disease.

53. Atherosclerosis atherosclerosis is a progressive disease and can develop in any artery in the atherosclerosis is the major form of heart disease in Western countries. http://www.mamashealth.com/atherosclerosis.asp

Mamashealth.com Home Heart Disease Pages Acyanotic Angina Atherosclerosis Arrhythmia ... Rheumatic Heart Disease Links Email Mama Atherosclerosis literally means "hardening of the arteries". It is a build up of cholesterol and other fat substances within the walls of the arteries. Atherosclerosis is a progressive disease and can develop in any artery in the body. It is a common disorder of the arteries. Atherosclerosis is the major form of heart disease in Western countries. Over one half of all deaths in the US are a direct or indirect result of atherosclerosis. Atherosclerosis is triggered by excess amounts of unstable particles known as oxygen-free radicals, which bind with and alter other molecules, a process called oxidation. The particles are usually released as part of normal bodily processes, but environmental toxins, such as viruses or smoking , can hinder the body from releasing them and produce excess amounts. In atherosclerosis, fatty deposits called plaque, build up on the inner wall of the coronary arteries. These fatty deposits usually develop over many years. Plaque is composed of a porridge-like accumulation of cholesterol and their compounds within a fibrous coat. Cholesterol buildup is very hazardous. After it builds up, the injury to the arteries signal the immune system to release white blood cells (particularly those called macrophages) at the site. This initiates a process called the inflammatory response. Macrophages literally "eat" the oxidized cholesterol leaving behind foamy cells that attach to the artery's smooth muscle cells. The foamy cells then buildup within the artery. After the immune system senses the foamy cells, it releases other factors called cytokines, which attract more white blood cells and perpetuate the whole cycle. This cycle usually repeats itself forming atherosclerotic lesions.

54. PAD A Severe Threat To Diabetics - Free Screening In September Discusses clogged or narrowed arteries in the legs due to atherosclerosis and where to find screening locations across the country. http://www.medicalnewstoday.com/medicalnews.php?newsid=27567&nfid=rssfeeds

55. Vls.icm.edu.pl/cgi-bin/sciserv.pl?collection=elsev Section of atherosclerosis and Lipoprotein Research (SALR Baylor College of Medicine has a research and clinical trials program exploringthe effectiveness of medications and other therapies in causing http://vls.icm.edu.pl/cgi-bin/sciserv.pl?collection=elsevier&journal=00219150

56. The Page You Are Trying To Access Has Been Deleted. A metaanalysis of epidemiologic Studies published in the New England Journal of Medicine indicates secondhand smoke causes heart attack, atherosclerosis or hardening of the arteries, congestive heart failure and other cardiovascular problems. http://216.185.112.5/presenter.jhtml?identifier=3172

57. Current Atherosclerosis Reports Current atherosclerosis Reports Current atherosclerosis Reports Currentatherosclerosis Reports Current atherosclerosis Reports http://www.current-reports.com/home_journal.cfm?JournalID=AT

58. Clear Your Arteries And Save Your Life. Method of clearing arteries that become blocked either fully or partially with fatty plaque. Information about cholesterol, heart attack, stroke, heart disease, angina, and atherosclerosis. http://www.arteryfacts.com

Members Area Username Passcode Clear your arteries and save your life. The very fact that you are looking at this website now means that there is a good chance you, or someone you know, suffers or suffered from: Cholesterol Coronary Heart Disease Angina Atherosclerosis ... Coronary Artery Disease All these conditions and many more coronary, artery or heart conditions are a result of furred up arteries; arteries that become blocked either fully or partially with fatty plaque known as atheroma. This one process of furring up the arteries causes all of the above conditions and is therefore the western world's biggest killer. Raymond Gaftarnick found out some four years ago that his arteries were blocked by up to 50%. When he asked the Consultant how serious this was, he was told "Put it this way, I wouldn't want arteries like yours at your age." "The consultants comments scared me into doing something." said Raymond,"I gathered as much information about my condition as possible from various different sources. I used this information to good effect by adding a handful of products that can be bought in your local supermarket to my daily diet."

59. Atherosclerosis Definition - Cholesterol: Health And Medical Information About H Medical information about cholesterol 100% Doctor produced written for patientsexperiencing high cholesterol levels to make informed health decisions. http://www.medterms.com/script/main/art.asp?articlekey=15018

60. Cardiovascular Medicine - UMass Medical School Has research programs in prevention and behavior, epidemiology, thrombosis, interventional technique, atherosclerosis, cardiac arrhythmias, gene therapy and nuclear cardiology. http://www.umassmed.edu/cardio/

directory contacts index this section only Cardiovascular Homepage Faculty Fellowship Program Cardiovascular Services ... cardiovascular medicine Welcome to the Division of Cardiovascular Medicine The Division of Cardiovascular Medicine has research programs in prevention and behavior epidemiology thrombosis interventional technique atherosclerosis cardiac arrhythmias gene therapy and nuclear cardiology. The Division has been involved in numerous NIH-sponsored research trials and studies including Thrombolysis in Myocardial Infarction (TIMI) Bypass Angioplasty Revascularization Investigation (BARI) Cardiac Arrhythmia Suppression Trial (CAST) Rapid Early Action for Coronary Treatment (REACT) Multicenter Unsustained Tachycardia Trial (MUSTT) Mode Selection for Sinus Node Dysfunction (MOST) and Worcester Area Trials for Cholesterol and Hyperlipidemia (WATCH). National Institutes of Health American Heart Association and non-federal sources. INTRANET top print This is an official Page/Publication of the University of Massachusetts Worcester Campus Cardiovascular Medicine 55 Lake Avenue North Worcester, MA 01605

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