101. BioMed Central | Full Text | Diagnosis And Therapy Of Invasive Aspergillosis In Invasive aspergillosis is an increasing cause of infectious morbidity after Invasive aspergillosis is a major cause of morbidity and mortality after http://www.biomedcentral.com/1523-3820/5/517

home journals A-Z subject areas advanced search ... Issue 6 Viewing options Abstract Full text PDF Related literature: Other articles by authors Wingard JR Leather HL Tools: E-mail to a friend Download references Opinion Diagnosis and Therapy of Invasive Aspergillosis in Hematopoietic Stem Cell Transplant Recipients John R Wingard MD and Helen L Leather BPharm BCPS Division of HematologyOncology, PO Box 100277, University of Florida Shands Cancer Center, Gainesville, FL, 32610, USA Current Treatment Options in Infectious Diseases Opinion statement Invasive aspergillosis is an increasing cause of infectious morbidity after hematopoi-etic stem cell transplantation (HSCT) and has a high case fatality rate. It is the main infectious challenge to HSCT clinicians. Reasons cited for poor treatment outcomes include difficulty in accurate diagnosis, which frequently results in late start of therapy, and therapies that are highly toxic or suboptimally effective. New diagnostics, including antigen assays such as galactomannan and beta glucan, and polymerase chain reaction assays offer hope that noninvasive means will make an early diagnosis in the course of infection. New therapies such as voriconazole for first- or second-line treatment, or caspofungin for second-line therapy, offer promise for less toxic and more efficacious therapies. Outline Introduction Opinion statement Introduction Treatment References Invasive aspergillosis is a major cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT). Two peaks of occurrence have been noted in observational studies. The first is before engraftment, during neutropenia. The second occurs later during the post-engraftment period, during corticosteroid use or occurrence of graft-versus-host disease (GVHD).

102. BioMed Central | Full Text | Invasive Aspergillosis In Patients With Hematologic Invasive aspergillosis has emerged as a common lifethreatening mycosis in The incidence of invasive aspergillosis (IA) has increased because of the http://www.biomedcentral.com/1523-3820/5/507

home journals A-Z subject areas advanced search ... Issue 6 Viewing options Abstract Full text PDF Related literature: Other articles by authors O'Shaughnessy EM Forrest GN ... Walsh TJ Tools: E-mail to a friend Download references Opinion Invasive Aspergillosis in Patients with Hematologic Malignancies: Recent Advances and New Challenges Elizabeth M O'Shaughnessy MD Graeme N Forrest MD and Thomas J Walsh MD PB IHS Building 10 Room 13N240 10 Center Drive, National Institutes of Health National Cancer Institute, Bethesda, MD, 20892, USA Current Treatment Options in Infectious Diseases Opinion statement Invasive aspergillosis has emerged as a common life-threatening mycosis in patients with hematologic malignancies. Early diagnosis and institution of antifungal drugs are critical in the management of these patients. Recent advances in the development of new antifungal agents have provided new strategies for the treatment of invasive aspergillosis. Voriconazole is indicated for the primary treatment of invasive aspergillosis. Lipid formulations of amphotericin B and caspofungin are indicated for patients who are intolerant or refractory to conventional amphotericin B deoxycholate. Despite this progress, treatment options remain unsatisfactory. There is great need for new therapies and novel drug targets. Outline Introduction Opinion statement Introduction Treatment References The incidence of invasive aspergillosis (IA) has increased because of the increasing numbers of patients with hematologic malignancies treated with high-dose chemotherapeutic agents and hematopoietic stem cell transplantation (HSCT). The antifungal agents approved for the treatment of IA have clinical response rates ranging from 33% and 52%

103. Pulmonary Aspergillosis - Invasive Type (Disease) - Detroit, Michigan Pulmonary aspergillosis invasive type (Disease) - courtesy of Henry Ford Health System of Detroit, Michigan. http://www.henryfordhealth.org/12075.cfm

Cardiac Surgery Cardiac Testing Electrophysiology Heart Transplant ... Related Content Related Content Pulmonary aspergillosis - invasive type (Disease) Aspergilloma Pulmonary aspergillosis Aspergillosis - chest X-ray Fungus Definition An acute infection of the lungs caused by a fungus that produces illness almost exclusively in immunosuppressed or immunodeficient people. Alternative Names Acute invasive aspergillosis; Aspergillosis - acute invasive Causes And Risk Aspergillosis is caused by a fungus (aspergillus) that is commonly found in the environment. It grows on dead leaves, stored grain, bird droppings, compost piles, or other decaying vegetation. It lung disease in three ways: as an allergic reaction in people with asthma ; as a fungus ball (aspergilloma) in an old healed lung cavity from previous disease such as tuberculosis or lung abscess , and as an invasive infection with pneumonia that may spread to other parts of the body by the bloodstream (invasive aspergillosis). Only the invasive infection is called invasive pulmonary aspergillosis and is much more serious than the other types of aspergillosis. The invasive infection can affect any organ of the body, but especially the heart, lungs, brain, and kidneys. Late in the course of the disease, the nervous system, skin, and other organs may become affected. Risk factors in addition to immunosuppression include a very low white blood cell count over a prolonged period. This is especially a problem in patients with prolonged neutropenia (low white blood cell counts) following chemotherapy or bone marrow transplantation.

104. Aspergillosis Healthopedia.com aspergillosis Precipitin (aspergillosis Precipitin)aspergillosis precipitin is a blood test that detects antibodies against a common fungus, The aspergillosis infection spreads in the bloodstream. http://www.websters-online-dictionary.org/definition/english/As/Aspergillosis.ht

Philip M. Parker, INSEAD. Aspergillosis Definition: Aspergillosis Aspergillosis Noun . Severe respiratory disease of birds that takes the form of an acute rapidly fatal pneumonia in young chickens and turkeys. . An opportunistic infection by a fungus of the genus Aspergillus; characterized by inflammation and lesions of the ear and other organs. . Disease especially in agricultural workers caused by inhalation of Aspergillus spores causing lumps in skin and ears and respiratory organs. Source: WordNet 1.7.1 Specialty Definition: Aspergillosis Domain Definition An infectious disease caused by the Aspergillus fungus. Orbital involvement is rare and is probably secondary to infection of the accessory nasal sinuses. Source: European Union. references Health Infections with fungi of the genus Aspergillus. ( references Source: compiled by the editor from various references ; see credits. Top Synonym: Aspergillosis Synonym: brooder pneumonia (n). ( additional references Top Crosswords: Aspergillosis English words defined with "aspergillosis" Aspergillus fumigatus references Specialty definitions using "aspergillosis" Aspergillosis, Allergic Bronchopulmonary

105. This Page Has Moved This page has moved, please update your bookmarks or links to the new address. http//www.cdc.gov/ncidod/hip/pneumonia/1_asper.htm http://www.cdc.gov/ncidod/diseases/hip/pneumonia/1_asper.htm

This page has moved, please update your bookmarks or links to the new address: http://www.cdc.gov/ncidod/hip/pneumonia/1_asper.htm You will be forwarded automatically in a few seconds. Division of Healthcare Quality Promotion National Center for Infectious Diseases Centers for Disease Control and Prevention Atlanta, GA

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