21. Statistics About Aortic Valve Disease - WrongDiagnosis.com Statistics about aortic valve disease as a medical condition including prevalence, incidence, death rates, and social and hospital statistics. http://www.wrongdiagnosis.com/a/aortic_valve_disease/stats.htm

Home Symptoms Diseases Risks ... Aortic valve disease Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Aortic valve disease Next sections Hospital Statistics for Aortic valve disease Glossary for Aortic valve disease Next chapters: Arteritis Atherosclerosis Embolism Primary pulmonary hypertension ... Feedback Statistics about Aortic valve disease About statistics: This page presents a variety of statistics about Aortic valve disease. The term 'prevalence' of Aortic valve disease usually refers to the estimated population of people who are managing Aortic valve disease at any given time. The term 'incidence' of Aortic valve disease refers to the annual diagnosis rate, or the number of new cases of Aortic valve disease diagnosed each year. Hence, these two statistics types can differ: a short-lived disease like flu can have high annual incidence but low prevalence, but a life-long disease like diabetes has a low annual incidence but high prevalence. For more information see

22. CTSN- Aortic Valve Disease Text aortic valve disease. Click on hyperlinked text for illustrations Annuloaortic ectasia is a disease of the aorta rather than the valve itself http://www.ctsnet.org/doc/7632

Aortic Valve Disease Click on hyperlinked text for illustrations View TSDA Curriculum Online for this topic 1. Morphology a) Calcified Aortic Stenosis bicuspid or unicuspid , fused commissures, heavy calcification, age 50-70 b) Rheumatic Aortic Stenosis Fibrous thickening , 3-cusp valve, mild calcification, rheumatic fever history in 1/2 c) Degenerative Aortic Stenosis nodular calcification , 3-cusp valve, no commissural fusion 2. Aortic Valve Incompetence Annulo-aortic ectasia is a disease of the aorta rather than the valve itself 3. Symptoms and Diagnosis a) Aortic Stenosis /M b) Aortic Incompetence 4. Natural History - Stenosis a) Hemodynamically severe, symptomatic or asymptomatic b) Hemodynamically mild or moderate, asymptomatic c) Hemodynamically mild or moderate, symptomatic 5. Natural History - Incompetence a) Latent period to cardiac decompensation is long b) Symptomatic patient with CHF, angina, syncope c) Asymptomatic patient 6. Associated Coronary Artery Disease 7. Ventricular Performance After AVR 8. Age and AVR

23. Mutations In NOTCH1 Gene Cause Aortic Valve Disease By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic http://www.sciencedaily.com/releases/2005/07/050719003022.htm

@import "/styles/navbar.css"; @import "/styles/tabStyles.css"; Set home page Bookmark site Add search Latest News ... Email to friend Text Size A A A Front Page ... Advertise With Us Source UT Southwestern Medical Center Date Print this page Email to friend Mutations In NOTCH1 Gene Cause Aortic Valve Disease DALLAS (July 17, 2005) By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic valve disease, a common heart birth defect as well as a major contributor to adult heart disease. In the study, available in the online edition of the journal Nature, researchers scanned the DNA of 11 members of a family that was affected with aortic heart disease. The patients ranged from children with severe narrowing of the aortic valve to 50- and 60-year-olds who had such severe calcium buildup on their heart valves that they required replacement valves. Related News Stories Heart Valve Disease Increases Risk Of Death, Research Shows (July 19, 1999) For decades, doctors have believed that early signs of aortic heart valve disease were harmless if the valve was functioning normally. But research by a Wake Forest University Baptist Medical Center ...

24. Mutations In NOTCH1 Gene Cause Aortic Valve Disease Mutations In NOTCH1 Gene Cause aortic valve disease The aortic valve is located between the left ventricle, or lower chamber of the heart, http://www.sciencedaily.com/print.php?url=/releases/2005/07/050719003022.htm

25. Mutations In NOTCH1 Gene Cause Aortic Valve Disease By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic http://www.eurekalert.org/pub_releases/2005-07/usmc-min071505.php

Public release date: 17-Jul-2005 E-mail Article Contact: John Watson jwatson@gladstone.ucsf.edu Gladstone Institute of Cardiovascular Disease Amanda Siegfried amanda.siegfried@utsouthwestern.edu UT Southwestern Medical Center Mutations in NOTCH1 gene cause aortic valve disease DALLAS – July 17, 2005 – By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic valve disease, a common heart birth defect as well as a major contributor to adult heart disease. In the study, available in the online edition of the journal Nature, researchers scanned the DNA of 11 members of a family that was affected with aortic heart disease. The patients ranged from children with severe narrowing of the aortic valve to 50- and 60-year-olds who had such severe calcium buildup on their heart valves that they required replacement valves. The UT Southwestern researchers found that all the relatives with some manifestation of aortic valve disease had a mutation in a gene called NOTCH1. A second, smaller family in San Diego afflicted with the heart disorder also had members with a second mutation in the same gene, providing convincing evidence that the researchers had found the genetic link to aortic heart disease, said Dr. Vidu Garg, assistant professor of pediatrics and molecular biology and lead author of the study.

26. Best Practice Medicine- Professional Reference - Aortic Valve Disease Cardiology, aortic valve disease. aortic valve disease. by David M Shavelle, MD, Best Practice of Medicine. March 2001. Last modified December 14, 2001. http://merck.micromedex.com/index.asp?page=bpm_brief&article_id=BPM01CA15

27. Best Practice Medicine-Professional Reference - Aortic Valve Disease Cardiology, aortic valve disease. Patients with significant aortic valve disease requires regular preoperative and postoperative monitoring, http://merck.micromedex.com/index.asp?page=bpm_report&article_id=BPM01CA15§i

28. YourHeart | Patient Information | Anatomy/Treatment | Aortic Valve Disease aortic valve disease. Where is the Aortic Valve? The Aortic valve is situated between Stenotic aortic valve disease is usually caused by one of three http://www.yourheart.org.uk/aortic.php

Search for Home About Us Patient Information Discussion Forum ... Sitemap Anatomy / Treatment Heart CHD / Angina Myocardial Infarction Iscaemic Heart Disease ... Heart Valves Aortic Valve Disease Mitral Valve Disease Pulmonary Valve Disease Tricuspid Valve Disease Endocarditis ... Useful Organisations You are here: Home Patient Information Anatomy / treatment Aortic Valve Disease Where is the Aortic Valve? The Aortic valve is situated between the left ventricle and the aorta, which is the main artery in the body, and prevents the back flow of blood once it has been pumped out of the heart. The valve may become damaged or diseased causing stenosis and/or regurgitation of the valve. Both of these complications may prevent the valve from functioning correctly. What is Aortic Stenosis? The Aortic valve may become narrowed or 'stenotic' causing the valve not to open fully. This will obstruct the forward flow of blood into the aorta from the left ventricle. What are the causes of Aortic Stenosis? Stenotic aortic valve disease is usually caused by one of three pathological processes: Rheumatic fever, which is another term for acute rheumatism.

29. Heart Info - Aortic Valve Disease HeartInfo.org provides the latest news and information on cardiovascular conditions, diseases, and treatments, fitness and nutrition tips, women s health, http://www.heartinfo.org/ms/ency/656/main.html

Health Encyclopedia Visit our medical encyclopedia and learn the definition, description, causes and risk factors, symptoms, diagnosis, treatment and prevention for heart attack, blood pressure, cholesterol, stroke and more. A B C D ... W Aortic Valve Disease Related Stories Is a Longevity Vaccine on the Way? Health Inflation Makes a Comeback Tarantulas Help Medical Science Creep Forward Related Videos Saving Hearts On The Road New And Improved Stroke Recovery Sighted Surgery Related Slides Angioplasty Atrial Fibrillation Congestive Heart Failure Related Encyclopedia Addison's Disease Aneurysms Angina Pectoris Definition of Aortic Valve Disease ... Questions To Ask Your Doctor About Aortic Valve Disease Definition of Aortic Valve Disease Aortic Valve Disease entails damage to, and dysfunction of, the aortic valve, one of the four valves in the heart. Description of Aortic Valve Disease The most common valvular problem in old age is aortic valve disease The aortic valve is one of four valves that control the flow of blood into and out of the heart. In particular, the aortic valve controls the flow of oxygenated blood pumped out of the heart from the left ventricle into the aorta, the main artery leading to the rest of the body. If the valve is abnormally narrow (aortic stenosis), the heart must work harder for a sufficient amount of blood to be pumped with each beat.

30. Valve Diseases Information on mitral and aortic valve diseases, including treatment options, from the Maryland Heart Center. http://www.umm.edu/heart/valve_diseases.html

var MenuLinkedBy='AllWebMenus [2]', awmBN='530'; awmAltUrl=''; Maryland Heart Center Request an Appointment About Us Virtual Tour ... Training Programs Related Resources Within UMM Artificial Organs Laboratory Translate using Google to Spanish German French Italian Portuguese Valvular Disease Valve Disease Overview Aortic Valve Disorders Mitral Valve Disorders Aortic Valve Repair and Replacement Mitral Valve Repair and Replacement Valvular heart disease occurs when the heart's valves no longer help regulate blood flow. The human heart contains four one-way valves that assure efficient unidirectional blood flow through the lungs and the systemic circulation. The two valves that most commonly become diseased and are responsible for the vast majority of clinical heart valve disease are the inlet (mitral) and outlet (aortic) valves of the main pumping chamber of the heart, the left ventricle. The valve may have a defect such as artificial narrowing (stenosis) which restricts blood flow, or may be weakened and cause regurgitation (where the blood is re-directed in the wrong direction). This disease may be caused by damage to the heart muscle as a result of rheumatic fever or a congenital abnormality. Over time, valve disease can cause the heart muscle to become overworked, and if left untreated can cause even further damages. Anatomy of the Valves Click on image for more information The mitral valve is the inflow valve to the left ventricle and is positioned between the left atrium, which receives blood from the lungs and the left ventricle. The mitral valve opens during relaxation of the left ventricle (diastole) and allows blood from the atrium to fill the ventricle. Contraction of the ventricle (systole) causes a rapid increase of pressure in the ventricle, which in turn results in closure of the mitral valve.

31. Learn About Aortic Valve Disease Treatment Options And Treatment Information At Treatment of aortic valve disease at Mayo Clinic, one of the largest and most experienced medical centers in the country for treatment of aortic valve http://www.mayoclinic.org/aortic-valve-disease/

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Aortic Valve Disease Aortic Valve Disease Overview Aortic Stenosis Aortic Regurgitation Diagnosis ... Medical Services Treatment of Aortic Valve Disease at Mayo Clinic Successful heart surgery at Mayo Clinic allows Heather Hinton to live a normal life despite rare genetic disorder. Read Heather's story. Research Mayo Clinic physicians and surgeons have published extensively about their research related to aortic valve disease. Read more about research Mayo Clinic is one of the largest and most experienced medical centers in the country for treatment of aortic valve disease ( aortic valve stenosis and aortic valve regurgitation ). Mayo Clinic heart surgeons have substantial expertise in repairing or replacing aortic valves. Diagnosis Several specialized tests are offered at Mayo Clinic to diagnose aortic valve disease. Read more about diagnosis of aortic valve disease Treatment Options Treatment options for aortic valve disease include careful monitoring, medications and surgery. Read more about aortic valve disease treatment options Treatment in Jacksonville, Fla.

32. Mayo Clinic: Treatment Options For Aortic Valve Disease Depending on the nature of the aortic valve disease, the following medications may be prescribed. Digitalis, which reduces the heart s workload and eases http://www.mayoclinic.org/aortic-valve-disease/treatment.html

Home About Mayo Clinic Jobs Contact Us Mayo Clinic Locations: Arizona Florida Minnesota Mayo Clinic ... Medical Services Aortic Valve Disease Aortic Valve Disease Overview Diagnosis Treatment Options Aortic Valve Surgery ... Medical Services Treatment Options for Aortic Valve Disease Patients with heart valve disease are at increased risk for getting bacterial endocarditis, an infection of the lining of the heart and its valves, which can progress rapidly and be fatal. They must take antibiotics prior to any dental and surgical procedures that might introduce bacteria into the bloodstream. Regular follow-up by healthcare providers is important. Actively observing the stability or the progression of aortic valve disease is important so that the right treatment can be started at the right time. Valves need to be repaired or replaced before irreversible damage occurs. Monitoring If tests reveal a mild to moderate condition and there are no symptoms, the physician will suggest scheduled checkups to carefully monitor the valve so medications can be prescribed or surgery done at the appropriate time. Medications People with heart valve disease are at increased risk for getting bacterial endocarditis , an infection of the lining of the heart and its valves, which can progress rapidly and be fatal. They must take antibiotics prior to any dental and surgical procedures that potentially could introduce bacteria into the bloodstream.

33. EMedicine - Aortic Valve Disease And The Ross Operation : Article By Gregory B D aortic valve disease and the Ross Operation Pulmonary valve autograft replacement of the aortic valve (ie, the Ross procedure) is an operative technique http://www.emedicine.com/ped/topic2823.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Cardiothoracic Surgery Aortic Valve Disease and the Ross Operation Last Updated: July 18, 2003 Rate this Article Email to a Colleague Synonyms and related keywords: aortic stenosis, aortic insufficiency, pulmonary valve autograft, Ross procedure AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Indications Relevant Anatomy And Contraindications ... Bibliography Author: Gregory B Dalshaug, MD , Assistant Professor, Division of Cardiovascular Surgery, Royal University Hospital Coauthor(s): Christopher A Caldarone, MD , Associate Professor of Surgery, The Hospital for Sick Children, University of Toronto; Phillip Camp, MD , Assistant Professor, Department of Surgery, Division of Cardiac and Thoracic Surgery, University of Kentucky College of Medicine Gregory B Dalshaug, MD, is a member of the following medical societies: American College of Surgeons American Medical Association Canadian Medical Association , Iowa Medical Society, and Royal College of Physicians and Surgeons of Canada Editor(s): Daniel S Schwartz, MD

34. EMedicine - Aortic Valve Disease And The Ross Operation : Article Excerpt By: Gr aortic valve disease and the Ross Operation Pulmonary valve autograft replacement of the aortic valve (ie, the Ross procedure) is an operative technique http://www.emedicine.com/ped/byname/aortic-valve-disease-and-the-ross-operation.

(advertisement) Excerpt from Aortic Valve Disease and the Ross Operation Synonyms, Key Words, and Related Terms: aortic stenosis, aortic insufficiency, pulmonary valve autograft, Ross procedure Please click here to view the full topic text: Aortic Valve Disease and the Ross Operation Pulmonary valve autograft replacement of the aortic valve (ie, the Ross procedure) is an operative technique used in selected cases for replacement of a diseased aortic valve. Superior hemodynamics, growth potential, and freedom from anticoagulation make it an attractive alternative to traditional aortic valve replacement with a mechanical or bioprosthetic valve. Because of the increased technical complexity of the procedure and concerns about the long-term durability of the autograft, some surgeons have reservations regarding the widespread use of the procedure. This article focuses mainly on aortic valve disease and the Ross procedure in neonates, children, and young adults. History of the Procedure: The procedure of replacing the aortic valve with the patient's own pulmonary valve and then using a pulmonary allograft to replace the pulmonary valve is commonly referred to as the Ross procedure. The concept was investigated by Lower, Stofer, and Shumway in 1959, using autotransplantation of the pulmonic valve into the descending thoracic aorta of dogs. Autotransplantation into the aortic annulus was described by Pillsbury and Shumway in 1966 and further popularized by Donald Ross in 1967 (see Image 1 ). Since then, the operation has steadily gained acceptance, and the indications for the procedure have expanded. The pulmonary autograft may be preferred in children and young adults because the living tissue offers the potential for growth, which is of major concern when replacing an aortic valve in this patient population.

35. The Cleveland Clinic > Quality Measures > Quality Guides > Heart Valve Disease How many aortic procedures for aortic valve disease are performed each year? At The Cleveland Clinic, over 1200 aortic procedures for aortic valve disease http://www.clevelandclinic.org/quality/guides/heartValve.htm

How Do You Judge Quality? Where Do You Begin? Searching the Internet Getting a Second Opinion ... Transplantation HEART VALVE DISEASE Credentials Experience Range of Services Patient Satisfaction ... Download a PDF Is the heart surgeon board-certified in thoracic surgery? All staff surgeons who perform valve procedures are board-certified in their surgical specialty or have the international equivalent. Is the cardiologist board-certified? All main campus Cleveland Clinic cardiologists involved in the management of valve patients are board-certified experts in the imaging of heart valves with multiple modalities such as two and three dimensional echos, MRI and CT scanning. Is the anesthesiologist board-certified? All staff cardiothoracic anesthesiologists are board-certified. To make an informed comparison, you may wish to ask your health care provider about his or her experience. How many transesophageal and intraoperative echocardiograms (TEEs and IOEs) are performed each year? The Cleveland Clinic performed over 5,600 TEEs and IOEs in 2003. The hospital has an intraoperative TEE service to ensure that the surgical outcome is optimal before the chest is closed in order to preclude the need for another operation. This service is provided for all patients undergoing valve repair at The Cleveland Clinic.

36. Aortic Valve Disease - Patient UK From Amazon browse hundreds of books on health and disease. Also, worth a look Related pages in Patient UK. PatientPlus. aortic valve disease http://www.patient.co.uk/showdoc/737/

Aortic Valve Disease UK sources of information and / or support See our valvular disease page Sponsored links and adverts Patient UK has no control of the content of the following links. Inclusion does not imply endorsement by Patient UK. Health Related Books From Amazon - browse hundreds of books on health and disease. Also, worth a look... Related pages in Patient UK Patient Plus Aortic Valve Disease Other - Useful resources Pictures, diagrams, photos, images, etc. Evidence based medicine Online textbooks and journals Guidelines ... Top of Page Further services Need an operation but on a waiting list ? Are you considering having it done privately but are not insured? Find the best prices for your operation Next of Kin . In an emergency, alerts paramedics with your vital medical or allergy information. Plus immediate contact with your family or next of kin. Health Insurance . Visit the Patient UK finance channel for quotes on health insurance and other financial products such as mortgages, life insurance, etc. Shopping . Visit the Patient UK Shopping Channel for a range of health and beauty products, gifts, electrical goods, and much more.

37. Aortic Valve Disease - Patient UK aortic valve disease Patient UK. A directory of UK health, disease, illness and related medical websites that provide patient information. http://www.patient.co.uk/showdoc/40000576/

PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people. Aortic valve disease The aortic valve is composed of 3 thin cusps that project from the wall of the origin of the aorta. These leaflets and their respective sinuses of Valsalva are called left, right, and noncoronary. They should allow unimpeded flow from the left ventricle to the aorta during systole and close swiftly and firmly to prevent backflow during diastole. Disease may lead to an impairment of outflow, permission of backflow or a combination of both. Aortic stenosis refers to a tight valve. A leaking aortic valve is variously called insufficiency, incompetence and regurgitation. It may be argued that a stenotic valve is also insufficient or incompetent and so perhaps regurgitation is to be preferred. Epidemiology Aetiology Aortic valve disease may be congenital or acquired. Post-rheumatic valve disease is becoming rarer and degenerative disease is more prominent in an aging population. It may be part of a more complex syndrome like Fallot’s tetralogy Prevalence Aortic valve disease occurs in 4 of every 1,000 births. There is a male preponderance of 3:1 in pure AS or AR but if there is also mitral valve disease there is a female preponderance. Over age 65, 2 to 3% of people have some degree of aortic stenosis.

38. Study Shows Mutation In NOTCH1 Gene Causes Aortic Valve Disease ? By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic http://www.news-medical.net/?id=11745

39. Aortic Valve - Information News Study shows mutation in NOTCH1 gene causes aortic valve disease. // Medical Study News. By studying five generations of a Dallas family, UT Southwestern http://www.news-medical.net/?keyword=Aortic valve

40. Mutations In NOTCH1 Gene Cause Aortic Valve Disease University of Texas Southwestern Medical Center at Dallas. http://www8.utsouthwestern.edu/utsw/cda/dept37389/files/232826.html

Advanced Search document.write(hashTable['Home'].parentMenu) Home News Current News Release Mutations in NOTCH1 gene cause aortic valve disease Latest News More Medical News Video News Releases En Espanol ... Publications Staff DALLAS - July 17, 2005 - By studying five generations of a Dallas family, UT Southwestern Medical Center researchers have discovered that a mutation in a key gene causes aortic valve disease, a common heart birth defect as well as a major contributor to adult heart disease. In the study, available in the online edition of the journal Nature , researchers scanned the DNA of 11 members of a family that was affected with aortic heart disease. The patients ranged from children with severe narrowing of the aortic valve to 50- and 60-year-olds who had such severe calcium buildup on their heart valves that they required replacement valves. The UT Southwestern researchers found that all the relatives with some manifestation of aortic valve disease had a mutation in a gene called Dr. Vidu Garg

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