21. Central Nervous System Involvement In The Antiphospholipid Central nervous system involvement in the antiphospholipid (Hughes) syndrome G. Sanna1 , M. L. Bertolaccini1 , M. J. Cuadrado1 2 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

22. Systemic Lupus Erythematosus Emerging Concepts Part 2 Emerging Concepts Part 2 Dermatologic and Joint Disease, the Antiphospholipid Antibody Syndrome, Pregnancy and Hormonal Therapy, Morbidity and http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

23. Antiphospholipid Syndrome APS is an autoimmune disease associated with thrombosis and pregnancy complications. Treatment with heparin and aspirin will improve the outcome. http://www.womens-health.co.uk/antiphos.asp

skip to: page content links on this page site navigation footer (site information) ... Links Women's Health Home Information about health conditions unrelated to pregnancy Problems and issues concerning early pregnancy Mid and late pregnancy information Get in touch and let us know what you think! Other websites which might be of interest www.womens-health.co.uk Women's Health Information Antiphospholipid syndrome What is it? Antiphospholipid syndrome (APS) is the name given to a disease which involves the immune system. Normally antibodies are good and they help fight germs or viral infections from outside, however, occasionally the immune system makes the wrong kind - a type that acts against the body itself. These unusual auto-antibodies in APS are detected by a blood test and when they are present make a person more likely to get specific problems. APS makes some people feel tired or can lead to aching joints but others have no symptoms at all. You can't catch it or give it to someone else and it isn't a terminal disease or anything like that. Many people go throughout life without even knowing their body makes these antibodies. Its just that there's more chance of certain problems. Sometimes APS is associated with a disease called systemic lupus erythematosis (SLE). Your doctor will have tested for this. It is only recently that these antibodies were discovered and their significance understood, so the information available is somewhat limited, but more research is being carried out on this all the time. We still don't know exactly how the antibodies bring about the effects described below, although we have some good ideas.

24. Neurological And Neuroendocrine-Cytokine Inter-relationship In The Neurological and NeuroendocrineCytokine Inter-relationship in the antiphospholipid syndrome JOAB CHAPMANa and YEHUDA SHOENFELDb http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

25. Antiphospholipid Syndrome Information on Hughe s Syndrome (anthiphospholipid antibody syndrome) including risks of the disease and current treatment options. http://www-admin.med.uiuc.edu/hematology/PtAPS.htm

University of Illinois - Urbana/Champaign Carle Cancer Center Hematology Resource Page Patient Resources Antiphospholipid Antibody Syndrome Home Factor V Leiden Antiphospholipid Syndrome General Clotting Information ... Protein S deficiency The antiphospholipid antibody syndrome, also known as Hughes Syndrome, is a disorder characterized by multiple different antibodies that are associated with both arterial and venous thrombosis (clots). There are three primary classes of antibodies associated with the antiphospholipid antibody syndrome: 1) anticardiolipin antibodies, 2) the lupus anticoagulant and 3) antibodies directed against specific molecules including a molecule known as beta-2-glycoprotein 1. Historically, antiphospholipid antibodies were first noted in patients who had positive tests for syphilis without signs of infection. Subsequently, a clotting disorder was associated with two patients with systemic lupus erythematosus in 1952. In 1957 a link between recurrent pregnancy loss and what is now called the lupus anticoagulant was established. Ultimately, the lupus anticoagulant was further described in 1963 and in 1972 the term lupus anticoagulant was given. In 1983, Dr. Graham Hughes described the association between antiphospholipid antibodies and arterial as well as venous thrombosis. There are two main classifications of the antiphospholipid antibody syndrome. If the patient has an underlying autoimmune disorder, such as systemic lupus erythematosus, the patient is said to have secondary antiphospholipid antibody syndrome. If the patient has no known underlying autoimmune disorder, it is termed primary antiphospholipid antibody syndrome.

26. Antiphospholipid Syndrome Obstetric Diagnosis, Management, And antiphospholipid syndrome Obstetric Diagnosis, Management, and Controversies D. Ware Branch, MD and Munther A. Khamashta, MD, PhD http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

27. Antiphosphlolipid Disorders The antiphospholipid syndrome may increase the risk of miscarriage, What is the treatment for the antiphospholipid syndrome in pregnancy? http://www.hygeia.org/poems4.htm

The Antiphospholipid Syndrome Vol.1 No.4 back home register by Sara Marder, M.D. Instructor and Fellow in Maternal and Fetal Medicine Department of Obstetrics and Gynecology Yale University School of Medicine Antiphospholipid Antibody Syndrome There are many causes that have been linked to recurrent pregnancy loss. One of the less frequently seen associations is known as the antiphospholipid antibody syndrome. What are antiphospholipid antibodies? Under normal circumstances, antibodies are proteins made by your immune system to fight substances recognized as foreign by your body. Some examples of foreign substances are bacteria and viruses. Sometimes the body's own cells are recognized as foreign. In the antiphospholipid antibody syndrome the body recognizes phospholipids (part of a cell's membrane) as foreign and produces antibodies against them. Antibodies to phospholipids (antiphospholipid antibodies) can be found in the blood of some people with lupus, but they are also seen in people without any known illness. Lupus anticoagulant (LAC) and anticardiolipin antibody (ACA) are the two known antiphospholipid antibodies that are associated with recurrent pregnancy loss. What is the antiphospholipid antibody syndrome?

28. BBC - Radio 4 - Case Notes 14/05/2005 Hughes Syndrome Hughes Syndrome, also called antiphospholipid syndrome or 'sticky blood', is a littleknown but widespread condition. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

29. The Antiphospholipid Syndrome (Hughes' Syndrome) The antiphospholipid syndrome (APS) is sometimes called sticky blood syndrome . This is because people with it have an increased tendency to form clots in http://www.netdoctor.co.uk/diseases/facts/antiphospholipid.htm

Search: All NetDoctor Diseases Medicines NetDoctor.co.uk Home News and features News News archive Newsletter Features Encyclopaedia Diseases Examinations Medicines Premium services SMS services StayQuit thediet Health centres ADHD Allergy and asthma Children's health Depression ... All health centres Discussion and support Discussion forums Support groups Services Ask the doctor Find a hospital Search Medline Test yourself Information About NetDoctor Commercial opportunities NetDoctor.com The antiphospholipid syndrome (Hughes' syndrome) Written by Dr MY Karim , lecturer in immunology, St Thomas' Hospital and Dr GRV Hughes , consultant physician and rheumatologist, St Thomas' Hospital What is the antiphospholipid syndrome (Hughes' syndrome)? The antiphospholipid syndrome (APS) is sometimes called 'sticky blood syndrome'. This is because people with it have an increased tendency to form clots in blood vessels (also known as thromboses). Any blood vessel can be affected including the veins, which are thin walled and take blood towards the heart, and the arteries, which have thick muscular walls, and take blood away from the heart. As a result of this clotting tendency these patients may develop repeated clots, eg in the veins of the leg (deep vein thrombosis), or in the arteries supplying the brain, causing a stroke. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy.

30. Introduction: Antiphospholipid Syndrome - WrongDiagnosis.com Introduction to antiphospholipid syndrome as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis. http://www.wrongdiagnosis.com/a/antiphospholipid_syndrome/intro.htm

Home Symptoms Diseases Risks ... Diseases Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Antiphospholipid syndrome Next sections Basic Summary for Antiphospholipid syndrome Types of Antiphospholipid syndrome Causes of Antiphospholipid syndrome Symptoms of Antiphospholipid syndrome ... Diagnostic Tests for Antiphospholipid syndrome Next chapters: Sjogren's Syndrome Thyroiditis Hypothyroidism Systemic Juvenile Rheumatoid Arthritis ... Feedback Introduction: Antiphospholipid syndrome Antiphospholipid syndrome: Autoimmune condition with antibodies against phospholipids. Researching symptoms of Antiphospholipid syndrome: Further information about the symptoms of Antiphospholipid syndrome is available including a list of symptoms of Antiphospholipid syndrome , or alternatively return to research other symptoms in the symptom center Causes of Antiphospholipid syndrome: Research more detailed information about the causes of Antiphospholipid syndrome , other possibly hidden causes of Antiphospholipid syndrome , or other general information about Antiphospholipid syndrome Contents for Antiphospholipid syndrome: Basic Summary for Antiphospholipid syndrome Types of Antiphospholipid syndrome Causes of Antiphospholipid syndrome Symptoms of Antiphospholipid syndrome ... Diseases Did we miss something? Please provide

31. Symptoms Of Antiphospholipid Syndrome - WrongDiagnosis.com Symptoms of antiphospholipid syndrome including signs, symptoms, incubation period, duration, and correct diagnosis. http://www.wrongdiagnosis.com/a/antiphospholipid_syndrome/symptoms.htm

Home Symptoms Diseases Risks ... Antiphospholipid syndrome Search our medical database Subscribe to our free Newsletter sample Send this page to a friend Condition Lists By Organ By Symptom By Class By Prevalence ... List A-Z Current chapter: Antiphospholipid syndrome Next sections Diagnostic Tests for Antiphospholipid syndrome Complications of Antiphospholipid syndrome Misdiagnosis of Underlying Causes of Antiphospholipid syndrome Associated Conditions of Antiphospholipid syndrome ... Glossary for Antiphospholipid syndrome Next chapters: Sjogren's Syndrome Thyroiditis Hypothyroidism Systemic Juvenile Rheumatoid Arthritis ... Feedback Symptoms of Antiphospholipid syndrome General information about symptoms of Antiphospholipid syndrome: The symptom information on this page attempts to provide a list of some possible symptoms of Antiphospholipid syndrome. This symptom information has been gathered from various sources, may not be fully accurate, and may not be the full list of symptoms of Antiphospholipid syndrome. Furthermore, symptoms of Antiphospholipid syndrome may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of symptoms and whether they are indeed symptoms of Antiphospholipid syndrome. List of symptoms of Antiphospholipid syndrome: The list of symptoms mentioned in various sources for Antiphospholipid syndrome includes: Hypercoagulation Thrombocytopenia Recurrent fetal loss Blood clotting Venous thrombosis Arterial occlusions Leg ulcers Hemolytic anemia Thrombocytopenia More symptoms of Antiphospholipid syndrome:

32. Antiphospholipid Syndrome Article describes antiphopholipid syndrome, its symptoms, diagnosis, and treatment. http://rarediseases.about.com/od/rarediseasesa/a/120504.htm

var zLb=8; var zIoa1 = new Array('Elsewhere on the Web','Yahoo! Groups: Antiphospholipid Syndrome','http://health.groups.yahoo.com/group/aplsuk/','Hughes Syndrome Foundation (UK)','http://www.hughes-syndrome.org/'); zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a70' About Rare / Orphan Diseases Rare Diseases A - B Rare Diseases: A Antiphospholipid Syndrome Rare Diseases Essentials Rare Diseases: Basic Information Rare Diseases Support Groups ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Rare / Orphan Diseases newsletter! See Online Courses Search Rare / Orphan Diseases Stay up to date! Compare Prices Email to a friend ... Print this page Elsewhere on the Web Yahoo! Groups: Antiphospholipid Syndrome Hughes Syndrome Foundation (UK) Most Popular Muscular Dystrophy ALD and Lorenzo's Oil Progeria Syndromes Leprosy (Hansen's Disease) ... The Elephant Man What's Hot Muscular Dystrophy Autoimmune Kidney Disease Minamata Disease Charcot-Marie-Tooth Disease ... Meckel-Gruber Syndrome adunitCM(150,100,'x55') Antiphospholipid Syndrome From Mary Kugler Your Guide to Rare / Orphan Diseases FREE Newsletter.

33. Antiphospholipid Syndrome Links to information and resources for antiphospholipid syndrome, also known as APLS and Hughes syndrome. http://rarediseases.about.com/cs/antiphospholipid/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a70' About Rare / Orphan Diseases Rare Diseases Essentials ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/6.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Rare / Orphan Diseases newsletter! See Online Courses Search Rare / Orphan Diseases Antiphospholipid Syndrome Guide picks An autoimmune disorder in which there are frequent blood clots produced, leading to strokes, heart valve disease, and in women, recurrent pregnancy loss. American Heart Association: Antiphospholipid Syndrome Brief information on the heart problems associated with antiphospholipid syndrome. Hygeia Foundation for Perinatal Loss and Bereavement Information on antiphospholipid syndrome and pregnancy loss. Women's Health: Antiphospholipid Syndrome Thorough information on the syndrome, from Women's Health, UK. Topic Index Email to a Friend Our Story Be a Guide ... New York Times Company Hurricane Katrina About's Hurricane Blogs NY Times Coverage Where to Donate Exclusive: One Family's Story ... How to Explain to Kids Related Topics Multiple Sclerosis Parenting Special Needs Sleep Disorders Headlines Cystic Fibrosis Foundation helps Hurricane Katrina victims Robert J. Beall, Ph.D, President and CEO of the Cystic...

34. Antiphospholipid Syndrome (APLS) A phospholipid is a fat (lipid) that contains phosphorous. It undergoes hydrolysis, which means it splits into fatty acids, glycerin and a nitrogen compound http://www.americanheart.org/presenter.jhtml?identifier=4459

35. CMAJ -- Please Take Our Questionnaire antiphospholipid syndrome is an autoimmune disease characterized by antiphospholipid antibodies 3 Pathogenic mechanisms in antiphospholipid syndrome. http://www.cmaj.ca/cgi/content/full/168/13/1675

Fall 2005 online survey of eCMAJ users For 50 weeks of the year, eCMAJ is available full-text online, free of charge and without registration. For 2 weeks only, from Sept. 7th to Sept. 18th, the price of admission is completion of a short survey. This survey will help us to understand more about our visitors and will take a maximum of 5 minutes to complete. You will have to fill it out only once from the computer you are now using, as long as you have cookies enabled in your Web browser. If you don't have time to complete the survey right now, click here for access to eCMAJ. We'll ask you again at your next visit. Your cookies need to be enabled for this to work properly. If you have already answered this survey, click here to access eCMAJ. Your cookies need to be enabled for this to work properly. If you have difficulties with this survey, please e-mail for assistance. cliquez ici cliquer ici pour obtenir de l'aide.

36. Antiphospholipid Syndrome. DermNet NZ Authoritative facts about the skin from the New Zealand Dermatological Society. http://dermnetnz.org/vascular/antiphospholipid-syndrome.html

@import url("/common/screen.css"); DermNet NZ Ad Authoritative facts about the skin from the New Zealand Dermatological Society Incorporated Home For patients For doctors ... Site map Search: Home Vascular Antiphospholipid syndrome What is antiphospholipid syndrome? Antiphospholipid syndrome (APS) is a disorder characterised by recurrent arterial or venous thrombosis and/or pregnancy losses, in the presence of persistently elevated levels of anticardiolipin antibodies and/or evidence of circulating lupus anticoagulant (these abnormalities are detected by blood tests). Primary APS occurs when there is no evidence of associated diseases. APS in the presence of an underlying disease, usually systemic lupus erythematosus , is called secondary APS. Who gets APS? APS occurs more commonly in young to middle-aged adults. However, it has also been found in a child as young as 8 months and in elderly people. Secondary APS appears to be more common in females and is most likely due to the fact that systemic lupus erythematosus and other connective tissue disorders have a female predominance. Younger patients with a history of deep vein thrombosis (DVT), pulmonary embolism, myocardial infarction, or cerebrovascular accidents (CVA), need to be investigated for APS, particularly if no other risk factors are present.

37. What The Heck Is Antiphospholipid Syndrome ? http//www.hughessyndrome.org/. Last time it took me several months to put the page up, hope we do better this time ) Hey, life sucks you just smile http://members.aol.com/AMAmail/Anti.html

htmlAdWH('93212823', '728', '90'); Main Any of you who have been touched bt APLS in the form of brain injury should be able to relate, I have Anoxia. This means Poor memory Poor concentration Lots of Mistakes Tough time figuring things out OOPs becomes a common part of your conversation. I was finaly going to fix some of the many dead links on the page. Bad Idea ...... A few simple key strokes and everything was gone .... Pooffffffff. But I am use to that, everyday occurance. Its just I cant remember how to get everything back where it was or where it came from or how it works. Ad to that that my "build a web page in an hour" Software that took me several months to learn is no longer supported. I dont know HTML! I only do point and click :) So, this could take some time To help out, these sites have some good links http://www.healthcyclopedia.com/antiphospholipid_syndrome.html http://www.silcom.com/~sblc/antibodies.html http://www.hughes-syndrome.org/ Last time it took me several months to put the page up, hope we do better this time :) Hey, life sucks ... you just smile and ignore it or it drives you nuts. If it drives you Nuts, APLS wins

38. Immunology And Uveitis Service | Medical Professionals | Articles | Case Reports antiphospholipid syndrome is defined as the presence of antiphospholipid The risk of thrombotic event in patients with antiphospholipid syndrome is 0.5 http://www.uveitis.org/medical/articles/case/antiphospholipid_syndrome.html

Treatment Algorithms Articles Textbook Clinical Trials ... Case Reports Antiphospholipid Syndrome by Erik Letko, M.D. CC (6/97): Blurry vision, headaches. HPI: A 55 year old woman complained of blurry vision in both eyes and headaches. The patient consulted her ophthalmologist who treated her Pred Forte and Atropine eye drops into both eyes without improvement. ROS: Hypertension, migraine, thyroid gland dysfunction, spastic colitis, colon polyps, anemia, recurrent UTIs, chlamydia, chills, fever, night sweat, fatigue, malaise, dizziness, paresthesia, alopecia, myalgia, arthralgia. Examination Visual acuity: 20/40 OD and 20/25 OS IOP: normal SLE: no conjunctival injection, one old keratic precipitate, 1/2+ flare and trace cells in the anterior chamber, 1+ posterior subcapsular cataract, 1/2+ vitreous cells, cell clumps adhered to the vitreous fibrils. Figure 5 . Fundus photograph of retinal periphery showing dot/blot hemorrhages. Assessment Uveitis OU Dot/blot hemorrhages OU Cataract OU Plan Work up of uveitis Fluorescein angiography OU Rule out underlying systemic disease Consider treatment Work-up Her work-up was significant for elevated levels of cholesterol, light density lipoproteins, triglycerides, erythrocyte sedimentation rate, C reactive protein, and anticardiolipin antibodies IgG and IgA. Urine analysis showed 4+ proteinuria, positive leukocyte esterase, bacteria, and presence of white blood cells. Fluorescein angiography showed vitreous opacity in both eyes and intraretinal dot/blot hemorrhage in OD.

39. Antiphospholipid Syndrome - Wikipedia, The Free Encyclopedia antiphospholipid syndrome, or antiphospholipid antibody syndrome, is a disorder of A very rare form is the catastrophic antiphospholipid syndrome, http://en.wikipedia.org/wiki/Antiphospholipid_syndrome

Wikimedia needs your help in the final days of its fund drive. See our fundraising page Over US$225,000 has been donated since the drive began on 19 August. Thank you for your generosity! Antiphospholipid syndrome From Wikipedia, the free encyclopedia. Antiphospholipid syndrome (or antiphospholipid antibody syndrome ) is a disorder of coagulation which causes thrombosis in both arteries and veins , as well as recurrent miscarriage . It is due to the autoimmune production of antibodies against cell membrane constituents. It is occasionally referred to as Hughes' syndrome after the rheumatologist Dr Graham R.V. Hughes ( St Thomas' Hospital London UK A very rare form is the catastrophic antiphospholipid syndrome , in which there is rapid organ dysfunction and arterial hypertension . It carries a high mortality Contents Signs and symptoms Laboratory Diagnosis Pathogenesis ... edit Signs and symptoms The presence of antiphospholipid antibodies (APLAs) is suggested by thrombosis ( arterial or venous ) and recurrent miscarriage (especially in the second trimester , but often earlier). Other common findings, although not part of the classification, are

40. Antiphospholipid Syndrome - Wikipedia, The Free Encyclopedia (Redirected from Antiphospholipid antibody). antiphospholipid syndrome (or antiphospholipid antibody syndrome) is a disorder of coagulation which causes http://en.wikipedia.org/wiki/Antiphospholipid_antibody

Wikimedia needs your help in the final days of its fund drive. See our fundraising page Over US$225,000 has been donated since the drive began on 19 August. Thank you for your generosity! Antiphospholipid syndrome From Wikipedia, the free encyclopedia. (Redirected from Antiphospholipid antibody Antiphospholipid syndrome (or antiphospholipid antibody syndrome ) is a disorder of coagulation which causes thrombosis in both arteries and veins , as well as recurrent miscarriage . It is due to the autoimmune production of antibodies against cell membrane constituents. It is occasionally referred to as Hughes' syndrome after the rheumatologist Dr Graham R.V. Hughes ( St Thomas' Hospital London UK A very rare form is the catastrophic antiphospholipid syndrome , in which there is rapid organ dysfunction and arterial hypertension . It carries a high mortality Contents Signs and symptoms Laboratory Diagnosis Pathogenesis ... edit Signs and symptoms The presence of antiphospholipid antibodies (APLAs) is suggested by thrombosis ( arterial or venous ) and recurrent miscarriage (especially in the second trimester , but often earlier). Other common findings, although not part of the classification, are

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