1. Antiphospholipid Syndrome - Arthritis And Arthritic Conditions, Medications, And A look at antiphospholipid antibody syndrome, what laboratory tests can support the diagnosis of this syndrome, what are the causes and how is it treated. http://www.medicinenet.com/antiphospholipid_syndrome/article.htm

document.writeln(''); MedicineNet Home Arthritis Home Page > Antiphospholipid Syndrome Search Tips Printer-Friendly Format FREE Newsletters Email to a Friend ... Next Antiphospholipid Syndrome Medical Author: William C. Shiel Jr., MD, FACP, FACR What is the antiphospholipid syndrome? What laboratory tests can support the diagnosis of the antiphospholipid syndrome? What causes the antiphospholipid syndrome? ... Antiphospholipid Syndrome At A Glance What is the antiphospholipid syndrome? The antiphospholipid syndrome is a disorder of the immune system that is characterized by excessive clotting of blood and/or certain complications of pregnancy (premature miscarriages, unexplained fetal death, or premature birth) and antiphospholipid antibodies (cardiolipin or lupus anticoagulant antibodies). Patients with antiphospholipid syndrome have developed abnormal symptoms while having antiphospholipid antibodies detectable in the blood. Antiphospholipid syndrome is also called the phospholipid antibody syndrome. Antiphospholipid syndrome has been referred to as Hughes syndrome in honor of the doctor who first described it. It is important to note that antiphospholipid antibodies can also be found in the blood of individuals without any disease process. In fact, antiphospholipid antibodies have been reported in approximately 2 percent of the normal population. Harmless antiphospholipid antibodies can be detected in the blood for a brief period occasionally in association with a wide variety of conditions, including bacterial, viral (hepatitis, HIV), and parasite (malaria) infections. Certain drugs can cause antiphospholipid antibodies to be produced in the blood, including antibiotics, cocaine, hydralazine

2. Antiphospholipid Syndrome MEDSTUDENTS-RHEUMATOLOGY A review about antiphospholipid syndrome, giving most importance on its clinical features, diagnosis and management. http://www.medstudents.com.br/reumat/reumat2.htm

RHEUMATOLOGY Luiz Eduardo da Costa Oliveira Rheumatology Resident Clementino Fraga Filho University Hospital / The Federal University of Rio de Janeiro Medstudents' Homepage Antiphospholipid Syndrome Definition The antiphospholipid syndrome is defined as a clinical disorder with recurrent arterial and venous thrombotic events, pregnancy wastage and/or thrombocytopenia in the presence of the lupus anticoagulant and/or moderate to high positive anticardiolipin test. Both a primary form, in patients without clinically or serologically evident autoimune disorders, and a secondary form, usually in patients with systemic lupus erythematosus, are recognized. This separation is solely for academical purposes. Clinical Features: A)Thrombosis Thrombosis may be present in small, medium, or large venous or arterial sites. The presentation is episodic and unpredictable. Venous thrombosis of a leg or arm, renal vein thrombosis, the Budd-Chiari syndrome, pulmonary embolism, Addison’s disease, retinal , sagital, pelvic, mesenteric, portal and axillary vein thrombosis have all been described. When an arterial site is involved, the manifestations may vary between the clinical features of a stroke or transient ischemic attack. When other arterial vascular beds are affected, such as the retinal, coronary, brachial, mesenteric, renal (interlobular arteries, arterioles and glomerular capillaries) and dermal arterioles, the clinical presentations are directly related to involved site. B)Pregnancy Loss

3. NORD - National Organization For Rare Disorders, Inc. Offers a brief discussion with a list of resources for more information. http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Antiphospholi

4. Redirect A look at antiphospholipid syndrome, what it is, problems it can cause, if it can be prevented, how common it is, and what to do. http://www.womens-health.co.uk/antiphos.htm

5. Mycoplasma Penetrans Bacteremia And Primary Antiphospholipid Syndrome Scientific case report of a patient with clinical features of PAPS infected with mycoplasma penetrans. http://www.cdc.gov/ncidod/eid/vol5no1/yanez.htm

Suggested Citation Dispatches Mycoplasma penetrans Bacteremia and Primary Antiphospholipid Syndrome Mycoplasma penetrans , a rare bacterium so far only found in HIV-infected persons, was isolated in the blood and throat of a non-HIV-infected patient with primary antiphospholipid syndrome (whose etiology and pathogenesis are unknown). Antiphospholipid syndrome (APS), first described in 1983 to 1986, is characterized by a wide variety of hemocytopenic and vaso-occlusive manifestations and is associated with antibodies directed against negatively charged phospholipids. Features of APS include hemolytic anemia, thrombocytopenia, venous and arterial occlusions, livedo reticularis, pulmonary manifestations, recurrent fetal loss, neurologic manifestations (stroke, transverse myelitis, Guillain-Barré syndrome); and a positive Coombs test, anticardiolipin antibodies, or lupus anticoagulant activity ( ). The factor(s) causing production of the antiphospholipid antibodies in primary antiphospholipid syndrome (PAPS) remain unidentified ( A substantial number of patients with Mycoplasma pneumoniae ). Furthermore, many clinical criteria for APS have also been well documented in patients with

6. Welcome To The Official Home Page Of The Hughes Syndrome Foundation Information about antiphospholipid syndrome, the symptoms, diagnosing and treatment. Also information about the foundation itself. http://www.hughes-syndrome.org/

Welcome to the official home page of the Hughes Syndrome Foundation. HUGHES SYNDROME (The Antiphospholipid Syndrome: APS A common disease Many clinical features Often undiagnosed Potentially treatable Latest news Kay Thackray's new book - More Sticky Blood Explained available to download NOW HSF Patients' Forum, 7th Sept 2005 - come meet the doctors ! HSF Sponsored London Bridges Walk - a fun day out for the family HUGHES SYNDROME or by doctors as: The Antiphospholipid Syndrome Young Stroke...

7. Antiphospholipid Syndrome An article about antiphospholipid syndrome with a discussion on diagnosis, symptoms and treatment are discussed. http://healthlink.mcw.edu/article/921732376.html

Search Articles: search tips Please Take the HealthLink Survey Email this article Print this article Find related articles: By topic: By keywords: Receive Health Link via email! Subscribe now >> Antiphospholipid Syndrome Antiphospholipid syndrome (APS) is characterized by the following: venous or arterial thrombosisa condition where clots, called thrombi, form in the blood vessels; recurrent miscarriagesthe repeated loss of the fetus in pregnancies; and thrombocytopeniaa low number of blood platelets that can lead to bleeding, seen as bruising and tiny red dots on the skin. Patients with APS also may experience symptoms of stroke such as transient ischemic attacks (TIAs). APS is diagnosed based on the above clinical manifestations and on laboratory test results. A blood sample is analyzed for the presence of antibodies that react with naturally occurring proteins complexed (bound together) with phospholipids. These are called antiphospholipid antibodies or anticardiolipin antibodies (cardiolipin is one type of phospholipid used in lab tests). Sometimes these antibodies are called lupus anticoagulants when clotting assays (a testing method) are used for their detection. The way in which these antibodies cause clinical problems is not well understood. Patients with APS may develop systemic lupus erythematosus, an autoimmune disorder (where antibodies fight against the body's own tissue); these patients should be followed periodically by a doctor who specializes in rheumatology. However, not all APS patients develop lupus. The tendency to have autoimmune disorders is inherited, but APS is not necessarily inherited. It is anticipated that continuing research will reveal more about the disease and lead to a greater understanding of all aspects of APS.

8. APSCORE: Home A national, NIHfunded, multicenter disease registry that supports a wide range of research into the causes, diagnosis, and treatment of APS. Includes links to enrollment sites. http://www.apscore.org

Welcome to the Antiphospholipid Syndrome Collaborative Registry (APSCORE), sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases ( NIAMS ) and the National Center on Minority Health and Health Disparities ( NCMHD ). The purpose of this national registry is to collect and update clinical, demographic, and laboratory data on patients with Antiphospholipid Syndrome (APS), as well as patients with antiphospholipid antibodies who do not have other symptoms commonly associated with APS. The registry also serves as a repository of blood samples from those enrolled in the registry. The registry is designed as a multi-center, multi-specialty, collaborative project involving a group of leading APS physicians at 8 academic medical centers . This approach allows for the recruitment of a large number of subjects, representing the full spectrum of APS clinical manifestations. The registry's coordinating center is housed in the Thurston Arthritis Research Center in the School of Medicine at the University of North Carolina at Chapel Hill.

9. Antiphospholipid Syndrome A look at antiphospholipid syndrome and the symptoms, cause of the blood clotting, diagnosis and treatment. http://www.med.umich.edu/1libr/aha/umantiphos.htm

Adult Health Topics All Health Topics Find a UMHS Doctor Search Adult Topics Search All Topics This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. Antiphospholipid Syndrome What is Antiphospholipid Syndrome? Antiphospholipid Syndrome is a disorder in which the blood clotting system begins to form blood clots in the veins or arteries without obvious reason. The symptoms of Antiphospholipid Syndrome include blood clots (thromboses) in leg or arm veins and/or arteries; blood clots which travel to the lungs (pulmonary emboli); sudden loss of vision; occasional episodes of numbness, tingling, or weakness in the face or limbs; stroke; seizures; and recurrent miscarriages. All of these symptoms are the result of blood clots occurring in small to medium sized blood vessels. Most people affected with this disorder have only one or two of any of these symptoms. They are however at risk for developing additional symptoms if not treated appropriately or monitored by a physician knowledgeable about the disorder. What causes the blood to clot too easily in Antiphospholipid Syndrome?

10. EMedicine - Antiphospholipid Syndrome : Article By Steven Carsons, MD antiphospholipid syndrome antiphospholipid syndrome (APS) is a disorder characterized by recurrent venous or arterial thrombosis and/or fetal losses http://www.emedicine.com/med/topic2923.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Rheumatology Antiphospholipid Syndrome Last Updated: December 5, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: APS, antiphospholipid antibody syndrome, aPL syndrome, anticardiolipin antibody syndrome, aCL syndrome, lupus anticoagulant syndrome, LA syndrome, Hughes syndrome, Sneddon syndrome, SLE, systemic lupus erythematosus, rheumatic disease, arterial thrombosis, anticoagulation, low-molecular-weight heparin, low molecular weight heparin, LMWH, unfractionated heparin, anticoagulation therapy, thrombosis, thrombosis prophylaxis AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Steven Carsons, MD , Chief, Division of Rheumatology, Allergy, and Immunology, Professor of Medicine, Department of Internal Medicine, Winthrop University Hospital, State University of New York at Stony Brook Coauthor(s): Elise Belilos, MD

11. Antiphospholipid Syndrome Among the topics discussed are primary and secondary APS, clinical manifestations, treatment and further reading. http://www.neuroland.com/cvd/aps.htm

Information for health care professionals click on brain to return to index page Neuroland Search site Neuro Med Neuro Note Texas Dr ... YSL Antiphospholipid Antibody Syndrome (APS) Primary APS: no underlying systemic disorder Secondary APS: presence of an underlying disease, most commonly SLE. Antiphospholipid antibody: two main groups. Lupus anticoagulants (LA): dRVVT used as both a screening and confirmatory test. It is a sensitive assay, provides accurate results during pregnancy. A prolonged dRVVT may be better than other tests for predicting arterial thrombosis. Anticardiolipin antibodies (ACA): Predictive value probably rises with the titer. Both IgG and IgM ACA may carry a risk, the correlation seems to be stronger with IgG antibodies. A mild increase involve very little risk. No direct correlation between the concentration of antibodies and extent of thrombosis. Whether elevated cardiolipin, phosphatidylserine, or phosphatidylethanolamine antibodies are a cause of stroke or are only a marker of the presence of other precursors of stroke remains unknown. Associated laboratory abnormalities: may include a prolonged activated partial thromboplastin time, false-positive VDRL, elevated ANA, ESR, thrombocytopenia.

12. Welcome To The Official Home Page Of The Hughes Syndrome Foundation Information about antiphospholipid syndrome, the symptoms, diagnosing and treatment. Also information about the foundation itself. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. EMedicine - Antiphospholipid Antibody Syndrome And Pregnancy : Article By Stella Antiphospholipid Antibody Syndrome and Pregnancy antiphospholipid syndrome (APS) is a recently recognized autoimmune condition that may manifest with http://www.emedicine.com/med/topic3258.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Medicine, Ob/Gyn, Psychiatry, and Surgery Obstetrics/gynecology Antiphospholipid Antibody Syndrome and Pregnancy Last Updated: July 20, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: lupus, lupus anticoagulant, LAC, antiphospholipid syndrome, APS, systemic lupus erythematosus, SLE, autoimmune disease, lupus erythematosus, LE, fetal loss, thrombosis, autoimmune thrombocytopenia, infertility, pregnancy complications, fetal mortality, fetal morbidity, maternal morbidity, spontaneous abortion, prematurity, stillbirth, fetal growth restriction, FGR, fetal growth retardation AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Stella Nowicki, DDS , Head of Infectious Diseases Laboratory, Associate Professor, Departments of Obstetrics and Gynecology, Microbiology and Immunology, University of Texas Medical Branch at Galveston Coauthor(s): Gregory Locksmith, MD

14. Antiphosphlolipid Disorders By Sara Marder, M.D. An explanation of this order and its association with pregnancy loss, who should be tested and its treatment. http://hygeia.org/poems4.htm

The Antiphospholipid Syndrome Vol.1 No.4 back home register by Sara Marder, M.D. Instructor and Fellow in Maternal and Fetal Medicine Department of Obstetrics and Gynecology Yale University School of Medicine Antiphospholipid Antibody Syndrome There are many causes that have been linked to recurrent pregnancy loss. One of the less frequently seen associations is known as the antiphospholipid antibody syndrome. What are antiphospholipid antibodies? Under normal circumstances, antibodies are proteins made by your immune system to fight substances recognized as foreign by your body. Some examples of foreign substances are bacteria and viruses. Sometimes the body's own cells are recognized as foreign. In the antiphospholipid antibody syndrome the body recognizes phospholipids (part of a cell's membrane) as foreign and produces antibodies against them. Antibodies to phospholipids (antiphospholipid antibodies) can be found in the blood of some people with lupus, but they are also seen in people without any known illness. Lupus anticoagulant (LAC) and anticardiolipin antibody (ACA) are the two known antiphospholipid antibodies that are associated with recurrent pregnancy loss. What is the antiphospholipid antibody syndrome?

15. Antiphospholipid Syndrome An article about antiphospholipid syndrome with a discussion on diagnosis, symptoms and treatment are discussed. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

16. Antiphospholipid Syndrome Among the topics discussed are primary and secondary APS, clinical manifestations, treatment and further reading. http://neuroland.com/cvd/aps.htm

Information for health care professionals click on brain to return to index page Neuroland Search site Neuro Med Neuro Note Texas Dr ... YSL Antiphospholipid Antibody Syndrome (APS) Primary APS: no underlying systemic disorder Secondary APS: presence of an underlying disease, most commonly SLE. Antiphospholipid antibody: two main groups. Lupus anticoagulants (LA): dRVVT used as both a screening and confirmatory test. It is a sensitive assay, provides accurate results during pregnancy. A prolonged dRVVT may be better than other tests for predicting arterial thrombosis. Anticardiolipin antibodies (ACA): Predictive value probably rises with the titer. Both IgG and IgM ACA may carry a risk, the correlation seems to be stronger with IgG antibodies. A mild increase involve very little risk. No direct correlation between the concentration of antibodies and extent of thrombosis. Whether elevated cardiolipin, phosphatidylserine, or phosphatidylethanolamine antibodies are a cause of stroke or are only a marker of the presence of other precursors of stroke remains unknown. Associated laboratory abnormalities: may include a prolonged activated partial thromboplastin time, false-positive VDRL, elevated ANA, ESR, thrombocytopenia.

17. What The Heck Is Antiphospholipid Syndrome ? Main Health Wellness Other Illnesses Conditions. What The Heck is antiphospholipid syndrome ? http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

18. Antiphospholipid Syndrome MEDSTUDENTS-RHEUMATOLOGY A review about antiphospholipid syndrome, giving most importance on its clinical features, diagnosis and management. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

19. Antiphospholipid Syndrome - Arthritis And Arthritic Conditions, Medications, And Explains arthritis conditions includes symptoms, causes, medications, and treatment. Written and reviewed by a Rheumatologist. http://www.medicinenet.com/antiphospholipid_syndrome/page2.htm

document.writeln(''); MedicineNet Home Arthritis Home Page > Antiphospholipid Syndrome Search Tips Printer-Friendly Format FREE Newsletters Email to a Friend Previous Antiphospholipid Syndrome Center Next Antiphospholipid Syndrome (cont.) In this Article What is the antiphospholipid syndrome? What laboratory tests can support the diagnosis of the antiphospholipid syndrome? What causes the antiphospholipid syndrome? How is the antiphospholipid syndrome treated? Antiphospholipid Syndrome At A Glance Antiphospholipid Syndrome Center What laboratory tests can support the diagnosis of the antiphospholipid syndrome? Patients with the antiphospholipid syndrome can have a variety of antibodies to phospholipids in their blood, including VDRL/RPR (a syphilis test that can be falsely positive in these patients), lupus anticoagulant, prolonged PTT, and cardiolipin antibody. As mentioned above, the anticardiolipin antibody has also been found in patients with the immune disease, systemic lupus erythematosus , which is characterized by the production of a variety of abnormal antibodies. What causes the antiphospholipid syndrome?

20. The Antiphospholipid Syndrome The antiphospholipid syndrome Vol.1 No.4 back home register by Sara Marder, M.D. Instructor and Fellow in Maternal and Fetal Medicine http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 1     1-20 of 107    1  | 2  | 3  | 4  | 5  | 6  | Next 20