61. Prions akinetic mutism. AND A typical EEG during any illness of any duration; akinetic mutism. AND No EEG or atypical EEG and duration 2 years. IATROGENIC http://www.thedoctorsdoctor.com/diseases/prions.htm

Background The Mad Cow Disease has struck terror in all consumers of beef. What is this microbe which is neither virus nor bacteria? Is it a new form of life or is it life? They have been termed prions and refers to an abnormal cellular protein resistant to most forms of viral inactivation. No DNA or RNA (nucleic acids fundamental to all life forms) have been found with prions. Prions is an acronym for proteinaceous infectious particles. They are the causative agents of a class of disease known as transmissible spongiform encephalopathies (TSE). Prions are a fascinating group of agents that challenge the conventional concepts of microbiology and even life. They contain no DNA or RNA and are conformational misfoldings of a normal protein. This mutated structure faciliates recruitment of other normal proteins into this abnormal structure. Prions have been implicated in several neurodegenerative diseases affecting many animals other than man. The noteriety of Mad Cow Disease, infecting cows in England, stems from the realization that the infectious agent causing the disease in the cows is the same agent causing Creutzfeld-Jakob disease in humans. Prior to this point, it was thought that each prion was species specific. Prions infect the central nervous system. Each of different prion strains have different incubation times and attack different portions of the brain.

62. Gigablast Search Results An article about akinetic mutism, what it is, the cause and symptoms.www.medterms.com/script/main/art.asp?articlekey=6990 26.5k - archived copy http://dir.gigablast.com/Health/Conditions_and_Diseases/Neurological_Disorders/B

Family filter: On Off Entire Directory Entire Category Pages in Base Category Sites in Base Category Top Health Medicine Net An article about akinetic mutism, what it is, the cause and symptoms. www.medterms.com/script/main/art.asp?articlekey=6990 [archived copy] [stripped] [older copies] - indexed: Apr 26 2005 Family filter: On Off Entire Directory Entire Category Pages in Base Category Sites in Base Category Try your search on gigablast google yahoo msn ... dmoz Help build the largest human-edited directory on the web. Submit a Site Open Directory Project Become an Editor

63. Portal Toolkit Invalid Site URL December 1998, 986 akinetic mutism a report of three Objectives Toreport 3 new cases of akinetic mutism, a clinical syndrome defined by silent http://ppv.ovid.com/pt/re/obes/abstract.00000132-199812000-00013.htm

Sorry, the URL specified, http://ppv.ovid.com:80/pt/re/obes/abstract.00000132-199812000-00013.htm , is invalid. To go to site for "OvidPPV" please click here http://ppv.ovid.com To go to site for "Acta Neurologica Scandinavica" please click here http://www.lwwonline.com To go to the LWW Online site, please click here http://www.lwwonline.com Thank you

64. Portal Toolkit Invalid Site URL Objectives To report 3 new cases of akinetic mutism, akinetic mutism (AM) (1)is a clinical syndrome liable to be induced by diversely localized http://ppv.ovid.com/pt/re/obes/fulltext.00000132-199812000-00013.htm

Sorry, the URL specified, http://ppv.ovid.com:80/pt/re/obes/fulltext.00000132-199812000-00013.htm , is invalid. To go to site for "OvidPPV" please click here http://ppv.ovid.com To go to site for "Acta Neurologica Scandinavica" please click here http://www.lwwonline.com To go to the LWW Online site, please click here http://www.lwwonline.com Thank you

65. Digital Binoculars akimbo; akin; akinesia; akinesia algera; akinesia amnestica; akinesic; akinesis;akinesthesia; akinetic; akinetic mutism; akinetic seizure; akiyami; http://www.webs-unlimited.co.uk/digital_binoculars.htm

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66. Efficacy Of Bilateral Pallidotomy The patient who experienced persistent akinetic mutism had ShyDrager syndromeand atypical PD. It is possible that with more rigorous selection of patients http://www.c3.hu/~mavideg/jns/2-3-8.html

Efficacy of bilateral pallidotomy Richard Kim, M.D., M.S., Ron Alterman, M.D., Patrick J. Kelly, M.D., Enrico Fazzini, D.O., Ph.D, David Eidelberg, M.D., Ph.D., Alaksandar Beric, M.D., D.Sci., and Djorje Sterio, M.D. New York University Center for the Study and Treatment of Movement Disorders, New York, New York; Department of Neurosurgery, New York University Medical Center, New York, New York; and North Shore University Hospital, Manhassett, New York The authors completed 11 of 12 attempted bilateral pallidotomies among 150 patients undergoing pallidotomy at New York University. In all but one patient, the pallidotomies were separated by at least 9 months. Patients were selected for bilateral pallidotomy if they exhibited bilateral rigidity, bradykinesia, or levodopa-induced dyskinesia prior to treatment or if they exhibited disease progression contralateral to their previously treated side. The Unified Parkinson's Disease Rating Scale (UPDRS) and timed upper-extremity tasks of the Core Assessment Protocol for Intracerebral Transplantation (CAPIT) were administered to all 12 patients in the "off" state (12 hours without receiving medications) preoperatively and again at 6 and 12 months after each procedure. The median UPDRS and contralateral CAPIT scores improved 60% following the initial procedure (p = 0.008, Wilcoxon rank sums test). The second pallidotomy generated only an additional 10% improvement in the UPDRS and CAPIT scores ipsilateral to the original procedure (p = 0.05). Worsened speech was observed in two cases. In the 12th case, total speech arrest was noted during test stimulation. Speech returned within minutes after stimulation was halted. Lesioning was not performed.

67. Little Audrey - Massachusetts, USA akinetic mutism ia a state in which a person is unspeaking (mute) and unmoving akinetic mutism is often due to damage to the frontal lobes of the brain. http://www.livingmiracles.net/Audrey.html

SEARCH THE SITE Last Updated: Thursday, 28 April, 2005 THE FILM Introduction LOCATIONS: Myrna Nazzour, Syria John Snide, USA Audrey Santo, USA The Vatican, Italy ABOUT THE FILM: Credits Press material Buy the film on DVD Foredrag ... Contact KNOWLEDGEBASE PHENOMENA: Stigmata Tears of Blood Incorruptible Bodies Eucharistic Miracles ... Holy Relics APPARITION SITES: Guadalupe, Mexico Lourdes, France Fatima, Portugal Garabandal, Spain IMPORTANT MIRACLES: The Holy Grail The Holy Lance Shroud of Turin The Holy Fire ... Syracuse, Italy Little Audrey - Mystic and Victim Soul The accident Audrey Santo before her accident. Suddenly Linda looked up with a vague sense of dread. Jennifer came down the stairs from her bedroom. Matthew was still on the floor. Stephen was coming in from outside. The German shepherd, Sting, which was usually patrolling the yard, for once, was inside the house. But where was Audrey? "She's outside, in the driveway" Stephen said. They rushed outside but Audrey was nowhere to be seen in front of the house. Within minutes, four paramedics arrived. By then, Audrey had no pulse and her eyes were fixed and dilated. Her blue skin color indicated she had been deprived of oxygen for a considerable time. She was strapped onto a stretcher and, escorted by a police cruiser to Worcester City Hospital.

68. Creutzfeldt-Jakob Disease Surveillance System In Canada, May 2002 - Blood Safety 3 akinetic mutism 4 - extrapyramidal symptoms 5 - ataxia 6 - pyramidal signs 5 - akinetic mutism. CT, cerebral/cerebellar atrophy, usually normal http://www.phac-aspc.gc.ca/hcai-iamss/cjd-mcj/cjdss-ssmcj/0502_e.html

Creutzfeldt-Jakob Disease CJD Home Page CJD-SS Family Information Physician Information ... Adobe Downloadable Document (493 KB) How to download PDF documents BULLETIN!!! Due to the recent use of new testing methods and techniques for 14-3-3 CSF protein analysis, we have noticed an increase in sensitivity of these techniques, resulting in a greater number of positive results. This phenomenon is being seen worldwide and is currently being assessed. It is therefore strongly recommended that the 14-3-3 protein analysis not be used as a screening test in the evaluation of Creutzfeldt-Jakob Disease patients, but rather as a test to be interpreted in conjunction with the overall clinical signs, symptoms and other investigations. May 2002 Highlights The 14-3-3 test must be used in conjunction with the overall clinical signs and symptoms of CJD. 121 confirmed cases of CJD identified by CJD-SS since inception. Incidence of CJD in Canada is as expected at 0.92 and 1.02 per million population.

69. Human Transmissible Spongiform Encephalopathies - CCDR Volume 25-01 - Health Can visual or cerebellar disturbance; pyramidal/extrapyramidal dysfunction;akinetic mutism; Chorea/dystonia or myoclonus; Dementia; akinetic mutism http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/99vol25/dr2501ea.html

Volume 25-01 1 January 1999 Table of Contents HUMAN TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES This article presents the conclusions and recommendations of the WHO Consultation on the global surveillance, diagnosis, and therapy of human transmissible spongiform encephalopathies which was held in February 1998 in Geneva. Bovine spongiform encephalopathy (BSE), a TSE affecting cattle, was first reported in the United Kingdom in 1986, and over 170,000 cases have been reported since then in that country alone. Relatively small numbers of cases have also been reported in native-born cattle in Belgium, France, Ireland, Luxembourg, the Netherlands, Portugal, and Switzerland. Cases have also been reported in Canada, Denmark, the Falkland Islands, Germany, Italy, and Oman, but solely in animals imported from the United Kingdom. In March 1996, the occurrence in the United Kingdom of 10 cases of an apparently new clinicopathologic variant of CJD (nvCJD) was announced. The temporal and geographic association with the BSE epidemic raised the possibility of a causal link. Evidence supporting this hypothesis has subsequently accumulated: (1) neuropathologic features similar to those of nvCJD are seen in macaque monkeys inoculated intracerebrally with brain material from confirmed cases of BSE; (2) transgenic mice (mice carrying only a human prion protein [PrP] gene) have now been shown to be susceptible to BSE; and (3) the biologic strain of the nvCJD agent (as defined by transmission characteristics of inbred strains of mice) and molecular 'strain' (as defined by the PrP glycosylation pattern) closely resemble the pattern in several animals which were naturally or experimentally infected with the BSE agent, but differ from those identified in sporadic CJD.

70. Addiction The end state is akinetic mutism, a kind of waking coma. They ll Before peoplestarted playing with Predictors, akinetic mutism was http://www.mindsay.com/tags/addiction

You are seeing this page because javascript is disabled To use MindSay, you must have a browser that supports javascript, and have it enabled. Login Blog Network Live! Addiction @ MindSay Addiction Slideshow Browse Tags Search Tags Related tags smoking emotions cigarettes drugs goDate(1126145476); raien 0 replies Reply now 24 fluid ounces of wholesome family fun I want to get a vertical labret. And I will. After the Renaissance Festival ends. Ta da. goDate(1124818825); lizfuel 7 replies Reply now You Know You're Addicted to LotR When... You Know You're Addicted to LotR When... You start quoting from the movie as part of regular conversation. You like to tell your mom that you are hungry by quoting: "Merry, I'm hungry." She used to just laugh, but now she says, "What would you like to eat, Pippin?" You continually ask your parents for second breakfast. All the staff at your local cinema knows you by your first name and even before you open your mouth to speak, they say "Ticket for 'Fellowship of The Ring?'" You hate Burger King food, butyou ate nothing else for a month to get the toys.

71. Clinical Symptoms Of Human TSEs Dysphasia; Cerebellar EEG changes; akinetic mutism; Primitive reflexes;Cortical blindness; Extrapyramidal EEG changes; Lower motor neuron signs http://w3.aces.uiuc.edu/AnSci/BSE/Human_TSEs_Clinical_Symptoms.htm

Sporadic CJD (sCJD) (85% of human TSEs) Familial CJD (fCJD) (~10% of human TSEs) Fatal Familial Insomnia (FFI) GSS 6 disorders Kuru vCJD Clinical symptoms at presentation Demetia Ataxia Behavioral disturbance Demetia Ataxia Behavioral disturbance Insomnia Dementia headaches limb pains sensory or phychiatric disturbances (depression/withdrawl) dysesthesia ataxia Clinical symptoms during course of illness Rapid clinical evolution Short total illness duration Dementia Myoclonus Pyramidal EEG changes Dysphasia Cerebellar EEG changes Akinetic mutism Primitive reflexes Cortical blindness Extrapyramidal EEG changes Lower motor neuron signs Seizures Rapid clinical evolution Short total illness duration Dementia Myoclonus Pyramidal EEG changes Dysphasia Akinetic mutism Primitive reflexes Cortical blindness Extrapyramidal EEG changes Lower motor neuron signs Seizures disruption of sleep/wake cycle myoclonus sympathetic hyperactivity dementia hallucinations stupor coma hyperhidrosin pyrexia tachycardia hypertension irregular breathing ataxia myoclonus dysarthria pyramidal signs cereballar ataxia myoclonus - less common limb ataxia dysarthria nstagmus dementia parkinsonism deafness blindness gaze palsies seizures numbness Pyramidal EEG changes Extrapyramidal EEG change s ataxia dysarthria limb rigidity or rigidity no myoclonus occasionally exaggerated startled response pathologic bursts of laughter dementia in late stages sometimes late stages placid mute unresponsive death often assoc. w/ decubitus ulcers

72. BSE And CJD Linkage disturbance develop, often late in the clinical course but progress with thedevelopment of severe cognitive impairment and a state of akinetic mutism http://w3.aces.uiuc.edu/AnSci/BSE/Human_vCJD_Linkage_to_BSE.htm

Possible link between BSE and Creutzfeldt-Jacob Disease Four cases of CJD among dairy farmers in the UK occurred in 1994-5 These cases resembled typical sporadic CJD . They did, however, highlight concern about the possible transmission of BSE to humans. In 1995, Britton and Bateman identified cases (2) of CJD in teenagers that had unusually kuru-type plaques. These are normally seen in only 5% of CJD cases. Patients have behavioral and psychiatric disturbances, early and progressive ataxia (failure of muscular coordination). The new cases had extensive plaque formation and identifiable patterns of prion protein immunostaining. These cases had similarities to iatrogenic CJD associated with peripheral inoculation of prions (cadaveric growth-hormone cases) and kuru which are also characterized by progressive ataxia, behavioral and psychiatric disturbances. These patients had no recognized risk factors for CJD (iatrogenic routes or previously recognized prion gene mutations), However, they did have some familial history of dementia (Collinge Subsequently, a consistent and previously unrecognized disease pattern was identified in 10 (currently 14) other cases of CJD. Six of these were diagnosed in 1994 and four in 1995. Some of the features of the disease are different from those of classic CJD and a consideration of the medical histories, genetic analysis, possibility of increased ascertainment and other possible explanations failed to provide an adequate explanation for the pattern. This cluster is being referred to as Variant CJD (

73. Paper Near the end of a patient s life, a condition known as akinetic mutism occurs.akinetic mutism (Pocchiari, 1998) is a motivation disorder where patients are http://webpages.marshall.edu/~adkins120/paper.html

Creutzfeldt-Jakob Disease and How Speech Therapy Can Help Creutzfeldt-Jakob is considered to be a transmissible dementia or transmissible spongiform encephalopathy, which means that the spread of the disease is similar to that of viruses. Further studies have shown that instead of a virus, Creutzfeldt-Jakob Disease or CJD, is considered to be caused by a proteinaceous infection agent or "prion" (Asher et al, 2000) that attacks nerve cells causing vacuolization, the formation of holes in the cell, and eventually cell death. To date there are no effective screening procedures or medications for early diagnosis or treatment (Henderson, 2000). Like other dementias, true diagnosis can only be made during autopsy. Title References Home

74. EMedicine - HIV-1 Encephalopathy And AIDS Dementia Complex : Article By Sofia Ya retardation and language impairment become obvious, leading to akinetic mutism . retardation and dementia, apraxia, paraparesis, and akinetic mutism. http://www.emedicine.com/neuro/topic447.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Neurological Infections HIV-1 Encephalopathy and AIDS Dementia Complex Last Updated: May 16, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Sofia Yahya, MD , Staff Physician, Department of Psychiatry, Barnes-Jewish Hospital, Washington University School of Medicine Coauthor(s): Mandeep Garewal, MD , Staff Physician, Department of Neurology, Saint Louis University School of Medicine Lauren J Schaben, MD , Staff Physician, Department of Neurology, Saint Louis University School of Medicine Florian P Thomas, MD, MA, PhD, Drmed , Director, Spinal Cord Injury Unit, St. Louis VAMC, Associate Program Dir, Associate Professor, Departments of Neurology, Molecular Virology, and Molecular Microbiology and Immunology, Saint Louis University School of Medicine Sofia Yahya, MD, is a member of the following medical societies:

75. EMedicine - Neurologic Complications Of Organ Transplantation : Article By Sasa Clinical manifestations include akinetic mutism, seizures, psychosis, encephalopathy,cortical blindness, opsoclonus, tremors, and headaches. http://www.emedicine.com/neuro/topic721.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Neurology Critical Care Neurology Neurologic Complications of Organ Transplantation Last Updated: March 28, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: opportunistic infection, immunosuppression, central nervous system infection, CNS infection, organ transplant, solid organ transplantation, kidney transplantation, liver transplantation, heart transplantation, lung transplantation, intestinal transplantation AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Sasa Zivkovic, MD, MSc , Assistant Professor, Department of Neurology, Division of Neuromuscular Diseases, University of Pittsburgh and VA Pittsburgh Healthcare System Coauthor(s): Oscar Mendez, MD , Chief Resident, Department of Neurology, University of Pittsburgh Medical Center Sasa Zivkovic, MD, MSc, is a member of the following medical societies:

76. Blackwell Synergy - Cookie Absent Dementia worsened gradually leading to akinetic mutism. She died five and a halfmonths after the onset of symptoms. MRI showed cerebral atrophy but failed http://www.blackwell-synergy.com/doi/abs/10.1111/j.1440-1789.2005.00595.x

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77. Autoaiuto Stato Vegetativo Dopo 10 Anni Si Sveglia E Parla 14 Vigilance and agitation for Frontal akinetic mutism akinetic mutism is differentfrom the Minimally Responsive State because the lack of movement and speech http://www.psicomed.it/uniarco/mod/forum/discuss.php?d=562&parent=729

78. Prion Page Later dementia develops progressing to akinetic mutism; myoclonus was also seenin most patients and sometimes was preceded by choreoathetosis. http://www.fortunecity.co.uk/roswell/psychic/24/prionpage/Project.htm

web hosting domain names photo sharing THE PRION DISEASES A Molecular and Genetic Perspective A dissertation By Robert J. Elbourn The prion diseases: a molecular and genetic perspective Contents Jump Jump Jump Jump ... Jump The number of -helices in PrP c c Jump Studies on transgenic mice to deduce the function of PrP c The overexpression of PrP c Demonstration of the requirement of PrP c for PrP sc Other studies directed at determining the function of PrP c Sc Jump Evidence for the conversion of PrP c into PrP sc Jump Other Possible PrP sc Jump Jump Jump Jump ... Jump Acknowledgements I would like to thank Dr. Ivor Brown and Dr. Glenn Telling for their invaluable support and advice. I would also like to acknowledge Prof. M. Alpers, Prof. J. Collinge, my friends and my family. R.J.Elbourn web hosting domain names web design online games ... Euroffice Section I: Introduction Aims of the study This study is aimed at looking at the prion diseases from a molecular point of view, taking into account the genetic as well as the transmissible and sporadic aspect of the diseases. It attempts to first fully identify these novel diseases to give an exact idea of what the research is about and why it is taking place. The molecular side starts by looking at the molecular and genetic evidence from the beginning of the discovery of the 'prion' hypothesis. Then, by following a fascinating path of logical deductions and discovery with exciting consequences that were revolutionary for molecular biology and resulted in uncertainties and fierce scientific debates, the properties of the prion diseases are investigated. The report intends to not only critically analyse the 'prion' hypothesis, but to compare it to the viral and bacterial hypotheses as well, ending in identifying the progress that needs to be made in the future, and above all, the major uncertainty of variant CJD.

79. Neurosurgery - UserLogin The patient developed akinetic mutism and panhypopituitarism, coupled with The akinetic mutism improved gradually, but he eventually required complete http://www.neurosurgery-online.com/pt/re/neurosurg/fulltext.00006123-200301000-0

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80. Neurosurgery - UserLogin separated into severe (coma, akinetic mutism, or other longterm, severe, severe, neurological deterioration (long-term coma and akinetic mutism). http://www.neurosurgery-online.com/pt/re/neurosurg/fulltext.00006123-199611000-0

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