81. Infectious Diseases In Clinical Practice - UserLogin Marked improvement in survival following aids dementia complex in the era ofhighly active antiretroviral therapy. Editor s Note This section of IDCP http://www.infectdis.com/pt/re/idcp/fulltext.00019048-200401000-00018.htm

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82. Bruce Brew aids dementia complex (ADC) cellular and viral pathogenesis The AIDS dementiacomplex and human immunodeficiency virus type 1 brain infection http://www.cfi.unsw.edu.au/Frames/bbresea.html

HIV/AIDS NEUROLOGY and NEUROIMMUNOLOGY GROUP LEADER Bruce Brew BREW GROUP MEMBERS www POSTDOCTORAL FELLOWS Gilles Guillemin Kieran Williams PROJECTS AIDS dementia complex (ADC): cellular and viral pathogenesis Quinolinic acid and the kynurenine pathway as mediators of neuronal damage Neural stem cells and their application to multiple sclerosis. 1. AIDS dementia complex (ADC): cellular and viral pathogenesis. ADC pathogenesis is poorly understood. Evidence exists for the importance of both the virus and the host. Our group is working on the importance of certain parts of HIV that may be preferentially able to cause damage to neurons. We are assessing this by using neurotropic strains of HIV and determining the extent of neuronal damage in a human neuronal tissue culture system. We are also examining the importance of the host in the pathogenesis of ADC by determining whether there is any relationship between ADC and certain chemokine receptor mutations. Lastly we are examining the clinical significance of a variety of antiretroviral drug resistance mutations in the cerebrospinal fluid in determining the presence of ADC and its response to therapy. Relevant publications: Brew BJ, Rosenblum M, Cronin K, Price RW. The AIDS dementia complex and human immunodeficiency virus type 1 brain infection: clinical-virological correlations. Ann Neurol 1995;38:563-570.

83. American Family Physician: AIDS-related Psychopathology aids dementia complex typically presents with apathy and psychomotor retardation.Progression to severe dementia is often accompanied by hallucinations. http://www.findarticles.com/p/articles/mi_m3225/is_n5_v40/ai_8267005

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles American Family Physician Nov 1989 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Related Searches HIV (Viruses) / Psychological aspects AIDS (Disease) / Psychological aspects Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports AIDS-related psychopathology American Family Physician Nov, 1989 Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. AIDS-Related Psychopathology A large number of psychiatric symptoms and diagnoses are now recognized as being associated with the human immunodeficiency virus (HIV) infection, acquired immunodeficiency syndrome and AIDS-related complex (ARC). According to Vomvouras, AIDS-related psychopathology can be divided into two broad areas: nonorganic conditions (or functional and reactive disorders) and organic neuropsychiatric conditions. There is considerable overlap between these two categories. The reactive disorders develop in response to stressors of the disease, while the organic conditions are psychiatric manifestations of either the primary HIV infection or its complications.

84. Indian Journal Of Medical Research: HAART & The Molecular Biology Of AIDS Dement Along with the reasons why aids dementia complex continues to be a problem in Key words aids dementia complex antiretroviral therapy - central nervous http://www.findarticles.com/p/articles/mi_qa3867/is_200504/ai_n13638644

@import url(/css/us/style1.css); @import url(/css/us/searchResult1.css); @import url(/css/us/articles.css); @import url(/css/us/artHome1.css); Advanced Search Home Help IN free articles only all articles this publication Automotive Sports 10,000,000 articles - not found on any other search engine. FindArticles Indian Journal of Medical Research Apr 2005 Content provided in partnership with 10,000,000 articles Not found on any other search engine. Featured Titles for AAACN Viewpoint ABNF Journal, The AIDS Treatment News AMAA Journal ... View all titles in this topic Hot New Articles by Topic Automotive Sports Top Articles Ever by Topic Automotive Sports Indian Journal of Medical Research Apr 2005 by Saksena, Nitin K Smit, Theresa K Save a personal copy of this article and quickly find it again with Furl.net. It's free! Save it. The era of highly active antiretroviral therapy (HAART) has led to a considerable decline in the HIV disease progression rates and HIV-1-related opportunistic infections especially in developed countries. Unfortunately, antiretroviral treatment for almost 90 per cent of the HIV-infected population is not available because of cost concerns. Although a number of studies have shown uniform impact of HAART on disease progression, its effect on treating HIV infection of the brain and its manifestations, such as AIDS dementia complex (ADC), remains unclear. Along with the reasons why AIDS dementia complex continues to be a problem in the era of HAART, this review also discusses the changes in ADC patterns with HAART and its relevance in developing countries such as India. In addition, an overview of various biological, molecular and therapeutic aspects that may influence HIV dementia (HIV-D) is provided.

85. AIDS Dementia Complex - Definition Of AIDS Dementia Complex In The Medical Dicti Definition of aids dementia complex in the Medical Dictionary and Thesaurus.aids dementia complex explanation. Information about aids dementia complex in http://medical-dictionary.thefreedictionary.com/AIDS dementia complex

Domain='thefreedictionary.com' word='AIDS dementia complex' Your help is needed: American Red Cross The Salvation Army join mailing list webmaster tools Word (phrase): Word Starts with Ends with Definition subscription: Dictionary/ thesaurus Computing dictionary Medical dictionary Legal dictionary Financial dictionary Acronyms Columbia encyclopedia Wikipedia encyclopedia Hutchinson encyclopedia AIDS dementia complex Also found in: Dictionary/thesaurus Acronyms 0.02 sec. Page tools Printer friendly Cite / link Email Feedback AIDS dementia complex n. The neurological disease complex that is sometimes experienced by AIDS patients, caused by neuron injury and death and characterized by cognitive impairment. Mentioned in No references found Medical browser Full browser AHF AHG Ahumada-Del Castillo syndrome AI ... AIDS AIDS dementia complex AIDS virus AIDS-related complex AIH ailment ... AIDS defining illnesses AIDS dementia complex AIDS denial AIDS denialism AIDS denialist AIDS denialists ... AIDS Law Project Word (phrase): Word Starts with Ends with Definition Free Tools: For surfers: Browser extension Word of the Day NEW!

86. The Body: AIDS Dementia The Body The Complete HIV/AIDS Resource From BBC News; aids dementia complexSurvival Is Up Dramatically in HAART Era (September 2, 2003) http://www.thebody.com/treat/neuro_dementia.html

@import url(/css/thebody.css); @import url(/css/subtopic.css); var zflag_nid="362"; var zflag_cid="1"; var zflag_sid="0"; var zflag_width="728"; var zflag_height="102"; var zflag_sz="26"; Just Diagnosed HIV Treatment Living With HIV HIV Around the World ... Conference Coverage AIDS Dementia The Basics Research The Basics Dementia and Nervous System Problems (May 28, 2005) To read PDF, click here From New Mexico AIDS InfoNet HIV Dementia Risk Causes New Concerns (October 16, 2002) In The Prevention News Update , from Centers for Disease Control and Prevention AIDS Dementia Complex (April 2002) To read PDF, click here From Project Inform Brain Drain: HIV-Associated Dementia and Memory Loss (April 2002) In HIV Treatment ALERTS!, from The Center for AIDS: Hope and Remembrance Project Facts About AIDS Dementia Complex (December 2000) In Survival News , from AIDS Survival Project Psychosocial Interventions in Persons With HIV-Associated Neuropsychiatric Compromise By Stephan L. Buckingham and Michael Shernoff Research CNS Penetration of Antiretroviral Agents May Not Be Essential for Prevention of AIDS-Related Dementia (February 25, 2005)

87. The Body: AIDS Dementia Complex aids dementia complex, at The Body, the complete HIV/AIDS resource. http://www.thebody.com/pinf/dementia.html

@import url(/css/thebody.css); @import url(/css/article.css); var zflag_nid="362"; var zflag_cid="1"; var zflag_sid="0"; var zflag_width="728"; var zflag_height="102"; var zflag_sz="26"; Just Diagnosed HIV Treatment Living With HIV HIV Around the World ... Conference Coverage Project Inform AIDS Dementia Complex April 2002 Table of Contents Possible Symptoms of Early Stage ADC Possible Symptoms of Middle Stage ADC Possible Symptoms of Late Stage ADC What Is ADC? ... Conclusion Dementia is a brain disorder that affects a person's ability to think clearly and can impact his or her daily activities. AIDS dementia complex (ADC) dementia caused by HIV infection is a complicated syndrome made up of different nervous system and mental symptoms. These symptoms are somewhat common in people with HIV disease. The frequency of ADC increases with advancing HIV disease and as CD4+ cell counts decrease. It is fairly uncommon in people with early HIV disease, but it's more common in people with severely weakened immune systems and symptoms of advanced disease. Severe ADC is almost exclusively seen only in people with advanced HIV disease. ADC consists of many conditions that can be of varying degrees and may progressively worsen. These conditions can easily be mistaken for symptoms of other common HIV-associated problems including depression, drug side effects or opportunistic infections that affect the brain like toxoplasmosis or lymphoma. Symptoms of ADC may include poor concentration, forgetfulness, loss of short- or long-term memory, social withdrawal, slowed thinking, short attention span, irritability, apathy (lack of caring or concern for oneself or others), weakness, poor coordination, impaired judgment, problems with vision and personality change.

88. Opportunistic Infections (OIs) -- Queer Lesbian Gay HIV Treatment -- Gay.com aids dementia complex (ADC), sometimes called HIVassociated dementia (HAD), isdifferent than other types of AIDS-related illnesses. http://www.gay.com/health/hiv/treatment/?sernum=2518

89. NGC - Browse Dementia, Amnestic, Cognitive Disorders List all 34 guidelines Dementia -List all 27 guidelines aids dementia complex - List all 2 guidelines http://www.guideline.gov/browse/browsemode.aspx?node=836&type=1

90. Welcome To NAME Constantin Yiannoutsos PHONE (317) 278-3045 in astrocytes as well as neurons in patients with aids dementia complex (ADC) . activation pathogenetic relationship to the aids dementia complex. http://medicine.iupui.edu/faculty/showme.asp?id=3262

91. Untitled aids dementia complex (ADC, HIVAssociated Cognitive/Motor Complex). AIDS DementiaComplex (ADC) JAMA A degenerative neurological condition attributed to http://treasuresoftheinternet.org/dictionary/aids/a/ad/ADC.shtml

Index: A# - AG AH - AM AN - AO AP - AZ AIDS Dementia Complex (ADC, HIV-Associated Cognitive/Motor Complex) AIDS Dementia Complex (ADC) JAMA A degenerative neurological condition attributed to HIV infection, characterized by a group of clinical presentations including loss of coordination, mood swings and loss of inhibitions, and widespread cognitive dysfunctions. It is the most common central nervous system complication of HIV infection. Characteristically, it manifests itself after the patient develops major opportunistic infections or AIDS-related cancers. However, patients can also have this syndrome before these major systemic complications occur. The cause of ADC has not been determined exactly, but it may result from HIV infection of cells or inflammatory reactions to such infections. AIDS Dementia Complex (ADC, HIV-Associated Cognitive/Motor Complex): SFAF mental impairment with an organic cause that is due to HIV infection (i.e., not an opportunistic pathogen). Symptoms may include cognitive impairment (e.g., difficulty concentrating, memory loss), disorientation, mood and personality changes, speech and vision difficulties, psychomotor dysfunction (lack of coordination, incontinence) and paralysis. AIDS-related dementia typically affects people in the later stages of HIV disease. Early stages of the syndrome are referred to as HIV-associated minor cognitive/motor disorder. Click on Sources to find source(s) of the term definition cited above (see superscript).

92. Scout Report Archives Browse Resources aids dementia complex. (1 classification). Classifications.Research (1). NSF Andrew W Mellon Foundation University of Wisconsin http://scout.wisc.edu/Archives/SPT--BrowseResources.php?ParentId=14025

93. Arch Neurol -- Abstract: Neuropsychological Characterization Of The AIDS Dementi Neuropsychological characterization of the aids dementia complex and rationalizationof a test battery. P. Maruff, J. Currie, V. Malone, C. McArthurJackson http://archneur.ama-assn.org/cgi/content/abstract/51/7/689

Select Journal or Resource JAMA Archives of Dermatology Facial Plastic Surgery Family Medicine (1992-2000) General Psychiatry Internal Medicine Neurology Ophthalmology Surgery Student JAMA (1998-2004) JAMA CareerNet For The Media Meetings Peer Review Congress Vol. 51 No. 7, July 1994 Featured Link E-mail Alerts ARTICLE Article Options Send to a Friend Readers Reply Submit a reply Similar articles in this journal Literature Track Add to File Drawer Download to Citation Manager PubMed citation Articles in PubMed by Maruff P Benson E Contact me when this article is cited Neuropsychological characterization of the AIDS dementia complex and rationalization of a test battery P. Maruff, J. Currie, V. Malone, C. McArthur-Jackson, B. Mulhall and E. Benson Neurophysiology and Neurovisual Research Unit, Mental Health Research Institute of Victoria, Parkville, Australia. OBJECTIVE: To define the neuropsychological deficits present in mild human immunodeficiency virus type 1 (HIV-1) associated with the acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) and to develop a rational neuropsychological test battery for its diagnosis. DESIGN: Survey.

94. Active Skim View Of: 4 DISEASE PROGRESSION AND INTERVENTION aids dementia complex shares with these disorders a slowing of thinking and SIGNIFICANCE OF aids dementia complex FOR OTHER CENTRAL NERVOUS SYSTEM http://books.nap.edu/nap-cgi/skimit.cgi?isbn=0309050936&chap=124-154

95. Title Page aids dementia complex. Transaxial slices in red scale Transaxial slices ingreen scale Sagittal slices in red scale Sagittal slices in green scale http://brighamrad.harvard.edu/education/online/BrainSPECT/AIDS/AIDS.html

PREV CASE Atlas of Brain Perfusion SPECT B. Leonard Holman Puneet K. Chandak Basem M. Garada NEXT ... CASE AIDS Dementia Complex HISTORY IMAGES FINDINGS TUTORIAL SLIDE SHOW RANDOM CASE FEEDBACK CONTENTS Comments and errors to Radweb@dsg.harvard.edu Additional information through chandak@dsg.harvard.edu Last updated: Aug 23, 1995 Redesigned June 1998

96. Clinical Trial: Comparison Of 2',3'-Dideoxyinosine (Didanosine, DdI) And Zidovud aids dementia complex HIV Infections, Drug Zidovudine Drug Didanosine Stage 1, 2, or 3 aids dementia complex. Estimated premorbid IQ of at least 70. http://www.clinicaltrials.gov/ct/show/NCT00000657

Home Search Browse Resources ... About Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex This study has been completed. Sponsors and Collaborators: National Institute of Allergy and Infectious Diseases (NIAID) Bristol-Myers Squibb Glaxo Wellcome Information provided by: National Institute of Allergy and Infectious Diseases (NIAID) ClinicalTrials.gov Identifier: Purpose To compare the safety and effectiveness of orally administered didanosine (ddI) with high dose orally administered zidovudine (AZT) in patients who develop or exhibit progression of the AIDS dementia complex (ADC) and who have not previously been intolerant to AZT at doses of up to 1000 mg/day. HIV-infected or AIDS patients may develop ADC which causes damage to the nervous system. ADC may be caused by some action of the AIDS virus on the nervous system, although similar problems can be caused by other infections because the AIDS virus lowers the body's ability to fight other infections. It is important to determine whether symptoms are due to ADC or to some other infection since treatment varies for different conditions. AZT has been shown to be beneficial to people with ADC although its effectiveness has only been studied in a small number of patients. Studies suggest that higher doses of AZT are more likely to be effective than standard doses in improving symptoms of ADC. Condition Intervention Phase AIDS Dementia Complex

97. Edward King - Anti-HIV Drugs And Dementia - 12/07/97 latest therapies at treating or preventing aids dementia complex (12/07/97) given several different names, including aids dementia complex or ADC. http://www.users.dircon.co.uk/~eking/features/dementia.htm

98. Karger Publishers Clinical Aspects of the aids dementia complex in Relation to Histopathological AIDS; aids dementia complex; HIV encephalitis; HIV leucoencephalopathy http://content.karger.com/ProdukteDB/produkte.asp?Doi=47972

99. AIDS Dementia Complex: Brain High-energy Phosphate Metabolite Deficits -- Bottom aids dementia complex brain highenergy phosphate metabolite deficits. PA Bottomley,CJ Hardy, JP Cousins, M Armstrong and WA Wagle http://radiology.rsnajnls.org/cgi/content/abstract/176/2/407

HOME HELP FEEDBACK SUBSCRIPTIONS ... TABLE OF CONTENTS QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: This Article Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Bottomley, P. A. Articles by Wagle, W. A. ARTICLES AIDS dementia complex: brain high-energy phosphate metabolite deficits PA Bottomley, CJ Hardy, JP Cousins, M Armstrong and WA Wagle General Electric Research and Development Center, Schenectady, NY 12301. To test whether compromised high-energy phosphate metabolism is implicated in the neurologic impairment of acquired immunodeficiency syndrome dementia complex (ADC), brain phosphate metabolite concentrations and ratios were measured noninvasively in 12 patients with mild to moderate ADC and 29 healthy volunteers by use of localized phosphorus-31 nuclear magnetic resonance (NMR) spectroscopy and proton (hydrogen-1) magnetic resonance (MR) imaging. In patients, brain phosphocreatine (PCr) and nucleoside

100. Dementia Complex, AIDS Definition - HIV: Health And Medical Information About HI medical information about HIV 100% Doctor produced written to inform and explainthe latest therapies with HIV. http://www.medterms.com/script/main/art.asp?articlekey=8734

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