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         Adrenoleukodystrophy:     more books (16)
  1. Adrenoleukodystrophy - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by ICON Health Publications, 2004-08-23
  2. The Official Parent's Sourcebook on Adrenoleukodystrophy: A Revised and Updated Directory for the Internet Age by Icon Health Publications, 2002-11-18
  3. Adrenoleukodystrophy: Webster's Timeline History, 1976 - 2007 by Icon Group International, 2009-06-06
  4. Adrenoleukodystrophy and Other Peroxisomal Disorders: Clinical, Biomedical, Genetic and Therapeutic Aspects - International Workshop Proceedings (International Congress)
  5. 21st Century Complete Medical Guide to Degenerative Nerve Diseases, Adrenoleukodystrophy, Leukodystrophy, Rett Syndrome, Canavan Disease, Ataxias, Authoritative ... for Patients and Physicians (CD-ROM) by PM Medical Health News, 2004-04-01
  6. Adrenoleukodystrophy: An entry from Thomson Gale's <i>Gale Encyclopedia of Neurological Disorders</i> by Karen, MS, CGC Krajewski, Rosalyn, MD Carson-DeWitt, 2005
  7. Gale Encyclopedia of Medicine: Adrenoleukodystrophy by John T. Lohr PhD, 2002-01-01
  8. Leukodystrophies: Adrenoleukodystrophy, Canavan Disease, Pelizaeus-Merzbacher Disease, Metachromatic Leukodystrophy, Krabbe Disease
  9. Adrenoleukodystrophy: An entry from Gale's <i>Gale Encyclopedia of Medicine, 3rd ed.</i> by John, PhD Lohr, 2006
  10. X-Linked Adrenoleukodystrophy - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers by Philip M. Parker, 2007-07-19
  11. Skin Conditions Resulting From Errors in Metabolism: Phenylketonuria, Adrenoleukodystrophy, Gout, Porphyria, Lafora Disease, Alkaptonuria
  12. Adrenoleukodystrophy: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Karen, MS, CGC Krajewski, 2005
  13. Adrenoleukodystrophy
  14. The Official Parent's Sourcebook on Adrenoleukodystrophy **ISBN: 9780597831072** by Icon Health Publications, 2002-11-01

41. Introduction: Adrenoleukodystrophy - WrongDiagnosis.com
Introduction to adrenoleukodystrophy as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.
http://www.wrongdiagnosis.com/a/adrenoleukodystrophy/intro.htm
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Next sections Basic Summary for Adrenoleukodystrophy Prognosis of Adrenoleukodystrophy Types of Adrenoleukodystrophy Doctors and Medical Specialists for Adrenoleukodystrophy ... Articles about Adrenoleukodystrophy Next chapters: Classic childhood ALD Adult-onset ALD Female carrier ALD Neonatal ALD ... Feedback
Introduction: Adrenoleukodystrophy
Adrenoleukodystrophy: Disorder of the myelin sheath of brain or spinal cord. Adrenoleukodystrophy: Adrenoleukodystrophy (ALD) is a rare, genetic disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. ALD is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath, the fatty covering — which acts as an insulator — on nerve fibers in the brain. Contents for Adrenoleukodystrophy: Footnotes: 1. excerpt from

42. Basic Summary For Adrenoleukodystrophy - WrongDiagnosis.com
Overview of adrenoleukodystrophy as a medical condition including introduction, prevalence, prognosis, profile, symptoms, diagnosis, misdiagnosis,
http://www.wrongdiagnosis.com/a/adrenoleukodystrophy/basics.htm
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Next sections Prognosis of Adrenoleukodystrophy Types of Adrenoleukodystrophy Doctors and Medical Specialists for Adrenoleukodystrophy Articles about Adrenoleukodystrophy ... Glossary for Adrenoleukodystrophy Next chapters: Classic childhood ALD Adult-onset ALD Female carrier ALD Neonatal ALD ... Feedback
Basic Summary for Adrenoleukodystrophy
Main name of condition: Adrenoleukodystrophy Other names or spellings: Addison-Schilder disease, ALD What is Adrenoleukodystrophy? Brief description of Adrenoleukodystrophy: Disorder of the myelin sheath of brain or spinal cord. Parent types of Adrenoleukodystrophy: Leukodystrophy Leukodystrophy Brain conditions Genetic Disease Organs Affected by Adrenoleukodystrophy: brain spinal cord Types of Adrenoleukodystrophy: Classic childhood ALD Adult-onset ALD Female carrier ALD Neonatal ALD How serious is Adrenoleukodystrophy? Prognosis of Adrenoleukodystrophy: Prognosis for patients with ALD is generally poor except after successful bone marrow transplantation. Death may occur within 1 to 10 years after the onset of symptoms due to disease progression.

43. BBC - Health - Conditions - Adrenoleukodystrophy
Dr Trisha Macnair takes an indepth look at adrenoleukodystrophy, a rare inherited disorder.
http://www.bbc.co.uk/health/conditions/adrenoleukodystrophy1.shtml
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Adrenoleukodystrophy
Dr Trisha Macnair Adrenoleukodystrophy (ALD) is a rare inherited disorder that leads to progressive brain damage, failure of the adrenal gland, and eventually death. Take a look at the causes.
In this article
What is it? What causes adrenoleukodystrophy? Progressive symptoms Treatment may delay progression
What is it?
ALD is one of a group of disorders called the leukodystrophies where the fatty covering of nerve fibres, called the myelin sheath, breaks down. There's no cure, although intensive research is being carried out for effective treatments. Parents watch with growing anxiety as their child becomes abnormally withdrawn or aggressive It's a devastating disease, not least because in its most severe form it starts to make its mark just as an apparently healthy young boy is beginning to leap and bound towards adult life. Parents watch with growing anxiety as their child becomes abnormally withdrawn or aggressive. A steady deterioration in brain function may then occur as the disease follows a relentless course towards death, which usually occurs within ten years of onset of symptoms and often much sooner.
What causes adrenoleukodystrophy?

44. Adrenoleukodystrophy - Lorenzo's Oil - DrGreene.com
adrenoleukodystrophy is one of the neurodegenerative diseases of childhood for which bone marrow transplantation is most successful.
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45. Adrenoleukodystrophy Medical Information
adrenoleukodystrophy Information from Drugs.com. adrenoleukodystrophy describes any of several closely related inheritable disorders of the breakdown
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Adrenoleukodystrophy
Definition
Adrenoleukodystrophy describes any of several closely related inheritable disorders of the breakdown ( metabolism ) of certain fats (long chain fatty acids). These disorders affect the adrenal glands , nervous system, and testes
Alternative Names
X-linked adrenoleukodystrophy; Melanodermic leukodystrophy; Neonatal adrenoleukodyrstophy; NALD
Causes
Adrenoleukodystrophy is transmitted as an X-linked trait (the neonatal form is by autosomal recessive transmission). It affects approximately 1 in 20,000 to 1 in 50,000 individuals from all races. It results in the accumulation of long chain fatty acids in the nervous system, adrenal gland, and testes, which disrupts normal activity. There are several (seven recognized) different forms of the disease.

46. AllRefer Health - Adrenoleukodystrophy (Melanodermic Leukodystrophy, NALD, Neona
adrenoleukodystrophy (Melanodermic Leukodystrophy, NALD, Neonatal Adrenoleukodyrstophy, XLinked adrenoleukodystrophy) information center covers causes,
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Alternate Names : Melanodermic Leukodystrophy, NALD, Neonatal Adrenoleukodyrstophy, X-Linked Adrenoleukodystrophy Definition Adrenoleukodystrophy describes any of several closely related inheritable disorders of the breakdown ( metabolism ) of certain fats (long chain fatty acid) that affects the adrenal glands , nervous system, and testes
Neonatal Adrenoleukodystrophy Adrenoleukodystrophy is transmitted as an X-linked trait (the neonatal form is by autosomal recessive transmission). Its

47. AllRefer Health - Neonatal Adrenoleukodystrophy - Adrenoleukodystrophy Pictures
Neonatal adrenoleukodystrophy adrenoleukodystrophy (Melanodermic Leukodystrophy, NALD, Neonatal Adrenoleukodyrstophy, X-Linked adrenoleukodystrophy)
http://health.allrefer.com/health/adrenoleukodystrophy-neonatal-adrenoleukodystr

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Web health.allrefer.com You are here : AllRefer.com Health Adrenoleukodystrophy : Neonatal Adrenoleukodystrophy
Adrenoleukodystrophy
Alternate Names : Melanodermic Leukodystrophy, NALD, Neonatal Adrenoleukodyrstophy, X-Linked Adrenoleukodystrophy
Neonatal Adrenoleukodystrophy
NALD is an inheritable disorder that affects the adrenal glands, the white matter of the brain and the testes. Some of the symptoms for this disorder include seizures, hyperactivity, crossed eyes, paralysis, hearing loss, and muscular weakness.
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48. Adrenoleukodystrophy (ALD): A Case Study Using The Film "Lorenzo's Oil"
**Sorry, WWNFF LPT can not answer questions regarding the film Lorenzo s Oil. ** We DO NOT have information on Lorenzo s condition. You may want to visit
http://www.woodrow.org/teachers/bi/1994/adreno.html
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49. Adrenoleukodystrophy - Patient Tree - Part Of TELEPLEXUS®
adrenoleukodystrophy Patient Tree - Patient To Patient Support Information - Part of TELEPLEXUS®
http://www.teleplexus.com/Adrenoleukodystrophy.html
My TELEPLEXUS About TELEPLEXUS TELEPLEXUS Mail TELEPLEXUS network: Addison's Disease Patient Tree Cyber Apostle Jersey Spin ... Home What is Adrenoleukodystrophy?
Adrenoleukodystrophy (ALD) is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath, an insulating membrane that surrounds nerve cells in the brain. People with ALD accumulate high levels of saturated, very long chain fatty acids (VLCFA) in the brain and adrenal cortex because they do not produce the enzyme that breaks down these fatty acids in the normal manner. The loss of myelin and the progressive dysfunction of the adrenal gland are the primary characteristics of ALD. ALD has two subtypes. The most common is the X-linked form (X-ALD), which involves an abnormal gene located on the X-chromosome. Women have two X-chromosomes and are the carriers of the disease, but since men only have one X-chromosome and lack the protective effect of the extra X-chromosome, they are more severely affected. Onset of X-ALD can occur in childhood or in adulthood. The childhood form is the most severe, with onset between ages 4 and 10. The most common symptoms are usually behavioral changes such as abnormal withdrawal or aggression, poor memory, and poor school performance. Other symptoms include visual loss, learning disabilities, seizures, poorly articulated speech, difficulty swallowing, deafness, disturbances of gait and coordination, fatigue, intermittent vomiting, increased skin pigmentation, and progressive dementia. In the milder

50. Adrenoleukodystrophy
CHC Wausau Hospital s Medical Library and Patient Education Center provides research services and healthcare information to physicians,
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Adrenoleukodystrophy
Definition
Adrenoleukodystrophy is a rare genetic disease characterized by a loss of myelin surrounding nerve cells in the brain and progressive adrenal gland dysfunction. Description
Adrenoleukodystrophy (ALD) is a member of a group of diseases, leukodystrophies, that cause damage to the myelin sheath of nerve cells. Approximately one in 100,000 people is affected by ALD. There are three basic forms of ALD: childhood, adult-onset, and neonatal. The childhood form of the disease is the classical form and is the most severe. Childhood ALD is progressive and usually leads to total disability or death . It affects only boys because the genetic defect is sex-linked (carried on the X chromosome). Onset usually occurs between ages four and ten and can include many different symptoms, not all of which appear together. The most common symptoms are behavioral problems and poor memory. Other symptoms frequently seen are loss of vision, seizures, poorly articulated speech, difficulty swallowing, deafness, problems with gait and coordination, fatigue, increased skin pigmentation, and progressive dementia The adult-onset form of the disease, also called adrenomyeloneuropathy, is milder, progresses slowly, is usually associated with a normal life span, and usually appears between ages 21-35. Symptoms may include progressive stiffness, weakness, or

51. ► Adrenoleukodystrophy
A medical encycopedia article on the topic adrenoleukodystrophy.
http://www.umm.edu/ency/article/001182.htm
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Adrenoleukodystrophy
Overview Symptoms Treatment Prevention Definition:
Adrenoleukodystrophy describes any of several closely related inheritable disorders of the breakdown ( metabolism ) of certain fats (long chain fatty acid) that affects the adrenal glands , nervous system, and testes
Alternative Names: X-linked adrenoleukodystrophy; Melanodermic leukodystrophy; Neonatal adrenoleukodyrstophy; NALD
Causes, incidence, and risk factors: Adrenoleukodystrophy is transmitted as an X-linked trait (the neonatal form is by autosomal recessive transmission). Its incidence is estimated at 1 out of 20,000 to 1 in 50,000 and affects all races. The metabolic defect is the accumulation of long chain fatty acids in the nervous system, adrenal gland, and testes , where the accumulated material disrupts normal activity. There are several (seven recognized) different forms of the disease. The neonatal form appears shortly after birth and includes seizures and delayed neurological development with death occurring in infancy or young childhood. The childhood cerebral form (around 4-8 years) appears in mid-childhood, and the other forms appear during

52. Neonatal Adrenoleukodystrophy - UMMC
Neonatal adrenoleukodystrophy. NALD is an inheritable disorder that affects the adrenal glands, the white matter of the brain and the testes.
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NALD is an inheritable disorder that affects the adrenal glands, the white matter of the brain and the testes. Some of the symptoms for this disorder include seizures, hyperactivity, crossed eyes, paralysis, hearing loss, and muscular weakness. Review Date: 6/22/2000 12:00:00 AM
Reviewed By:J. Gordon Lambert, MD, Associate Medical Director; G. Eric Morgan, MS3; RxRemedy

53. Demyelinating Diseases
adrenoleukodystrophy Alexander Disease - Canavan Disease - Demyelinating Diseases The X-linked adrenoleukodystrophy Database Project Moser et al.
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Diseases and Disorders Links pertaining to Demyelinating Diseases Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Adrenoleukodystrophy Alexander Disease Canavan Disease Demyelinating Diseases ... Neuromyelitis Optica
Demyelinating Diseases The Myelin Project [the Odone family et al.] - Washington DC (US) Brief Synopses of White Matter Disease: demyelinating , and White Matter Disease: dysmyelinating - CHORUS, Med College of Wisconsin (US)
Diffuse Cerebral Sclerosis of Schilder About Alpers disease - NINDS Alpers disease information - Institute of Child Health, NHS (UK)
Multiple Sclerosis About Multiple Sclerosis - Merck Manual, Home Edition Multiple Sclerosis: Current Status and Strategies for the Future - NAP 2001 (US) The US Nat'l Multiple Sclerosis Society including an extensive Source Book and a chapter about MS and Magnetic Resonance Imaging (MRI) Advances in Diagnosing Multiple Sclerosis - SW Med Center, Dallas, Sep 2003 (US)

54. Adrenoleukodystrophy
a CHORUS notecard document about adrenoleukodystrophy.
http://chorus.rad.mcw.edu/doc/00014.html
CHORUS Collaborative Hypertext of Radiology Nervous system About CHORUS
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adrenoleukodystrophy
  • X-linked recessive
  • demyelination of cerebral white matter
  • adrenal insufficiency (unresponsive to ACTH)
  • CT: white-matter dz: occipital regions > frontal
    • progression > generalized atrophy
  • MRI: hypointense T1/hyperintense T2, atrophic splenium of corpus callosum
  • NM: increased uptake in involved regions see also: dysmyelinating dz white-matter dz
Charles E. Kahn, Jr., MD - 2 February 1995
Last updated 26 May 2004
Related CHORUS documents:
leukodystrophy dysmyelinating disease metachromatic leukodystrophy white-matter disease ... Alexander disease
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AJR American Journal of Roentgenology PubMed : index to biomedical literature ...

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55. Adrenoleukodystrophy
What is adrenoleukodystrophy. adrenoleukodystrophy. ALD is the acronym for a rare genetic disease called adrenoleukodysrophy. Due to its unique pattern
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What is ALD?: Adrenoleukodystrophy Current Therapies Gene Therapy
Adrenoleukodystrophy
ALD is the acronym for a rare genetic disease called adrenoleukodysrophy. Due to its unique pattern of inheritance, and the fact that any individual may undergo random gene mutations, this horrible disease can make its devastating and often lethal appearance without any warning. ALD does not recognize racial, social, economic, or religious boundaries. It does, however, manifest preferentially in males. It is commonly known, especially to Americans, as the Lorenzo's Oil disease, named after an Oscar nominated 1993 film, starring Susan Sarandon and Nick Nolte, which was based on one family's experience. ALD affects boys and young men. In the childhood presentation, which is observed in 35% of ALD-positive individuals, it is usually diagnosed between the ages of four and ten years old. They generally have a history of learning disabilities and/or a behavior issue such as attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) while in fact, insulating material in the boys' brains, the white matter (also known as myelin) is progressively being destroyed. The disease worsens over several years, and usually in less than two years from ALD diagnosis, the child will lose all cognitive, mental, and physical functions, and deteriorate into a vegetative state leading to death.

56. ADRENOLEUKODYSTROPHY: Contact A Family - For Families With Disabled Children: In
Contact a Family is a UK charity for families with disabled children. We offer information on specific conditions and rare disorders.
http://www.cafamily.org.uk/Direct/a24.html
printer friendly ADRENOLEUKODYSTROPHY home how we can help medical information index of conditions ... how you can help Did you find this page
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yes no Adrenoleukodystrophy: Schilder's disease; Sudanophilic Leukodystrophy Adrenoleukodystrophy (ALD) is a life threatening genetic disorder which only occurs in males and affects the adrenal gland and white matter of the nervous system. It is caused by the accumulation of long chain fatty acids in the cells and tissues of an affected child. ALD was first recognised in 1923 and since then several hundred cases have been reported from many countries. There are several forms of ALD. In the severe (childhood cerebral) form, boys usually develop normally until they reach between the ages of 4-10 years of age when behavioural changes, such as loss of memory and emotional instability, may be experienced in varying degrees. There may also be difficulty with vision, hearing and motor function. Adrenal function may also be impaired ( Addison disease ) leading to nausea, vomiting, and changes in skin colour. Addison disease is commonly associated with gonadotrophin deficiency and may present with failure to enter puberty. There is continuous progressive deterioration of the nervous system. The rate of deterioration varies in each individual child.

57. Help With ALD (adrenoleukodystrophy)
adrenoleukodystrophy (ALD) is a rare, genetic disease for which there is no effective treatment or cure. It is best known as the disease portrayed in the
http://www.run4ald.org/
contact the chairman Race Details Registration Form Directions ... Photos 2002
What is ALD?
Adrenoleukodystrophy (ALD) is a rare, genetic disease for which there is no effective treatment or cure. It is best known as the disease portrayed in the 1993 movie "Lorenzos Oil" starring Nick Nolte and Susan Sarandon. ALD manifests primarily in males, and often progresses rapidly boys and young men who are affected typically lose all cognitive and physical functions, and deteriorate into a vegetative state leading to death in two to three years.
Who Will this Event Benefit?
All of the proceeds of the Run For ALD will benefit the Kennedy Krieger Institute , a non-profit hospital dedicated to treating, preventing and ultimately curing ALD and other neurogenetic diseases. Home Directions Get Involved About ALD 2002-2003 The run4ald.org© and jollybelly.com

58. FSP Syndromes
l adrenoleukodystrophy protein (ALDP) ; Chromosome Xq28; Recessive. Genetics. Multiple point mutations deletions (6%) 100 different
http://www.neuro.wustl.edu/neuromuscular/spinal/fsp.html

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FAMILIAL SPINAL CORD SYNDROMES
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Familial Spastic Paraplegia ( SPG

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: Spastin; 2p22
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Recessive

: Paraplegin; 16q24
(Troyer): Spartin; 13q12.3
(Mast): Maspardin; 15q22 Infantile onset : Alsin; 2q33 SPOAN X-linked : Proteolipid protein; Xq22 Other: Deafness Familial Spastic Paraplegia +... Ataxia CNS Ocular PNS ... Systemic Disorders Leukodystrophies Adrenomyeloneuropathy : ALDP; Xq28 Adult-onset Krabbe : GalC; 14q31 MLD : Arylsulfatase A; 22q13 Familial Spinal Cord Syndromes AAA syndrome : Aladin; 12q13 Adrenomyeloneuropathy : ALDP; Xq28 Alexander : GFAP; 17q21; Dominant Alzheimer's : Presenilin 1; 14q24; Dominant Arnold-Chiari Malformation (SPG9): 10q23; Dominant Cavanagh's Cerebral palsy-Symmetrical Cerebrotendinous xanthomatosis : Cytochrome 450; 2q33 Charlevoix-Saguenay : Sacsin; 13q11 Deafness : X-linked DRPLA : DRPLA protein; 12p13; Dominant Dystonias: DOPA-responsive Episodic ataxia : 1p; Dominant Evans Fitzsimmons syndrome Friedreich ataxia : FRDA; 9q13 Hereditary Motor Syndromes HHH syndrome HMN + UMN signs : Senataxin; 9q34

59. Adrenoleukodystrophy (ALD) Prevention, Cure, Curing Protocol, Remedies, Herbs, A
Ailments Illness adrenoleukodystrophy (ALD) adrenoleukodystrophy (ALD) Prevention Curing Protocol. adrenoleukodystrophy (ALD) To Read
http://curezone.com/dis/1.asp?C0=860

60. Adrenoleukodystrophy
adrenoleukodystrophy Updated May 18, 2004 What Is adrenoleukodystrophy? adrenoleukodystrophy Foundation. Clinical Trials
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