21. The Pituitary Society - Furthering The Understanding Of Diseases An organization to furthering the understanding of diseases of the pituitary gland http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

22. EMedicine - Gigantism And Acromegaly : Article By Melanie Shim, MD Gigantism and acromegaly Gigantism refers to the excessive linear growth that occurs with growth hormone (GH) excess when epiphyseal growth plates are http://www.emedicine.com/ped/topic2634.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Pediatrics Endocrinology Gigantism and Acromegaly Last Updated: July 29, 2004 Rate this Article Email to a Colleague Synonyms and related keywords: growth hormone excess, GH excess, giantism, gigantosoma, giant, hypersomia, somatomegaly, acromegalia, endocrine system, pituitary gland, abnormal growth AUTHOR INFORMATION Section 1 of 11 Author Information Introduction Clinical Differentials ... Bibliography Author: Melanie Shim, MD , Clinical Instructor, Department of Pediatrics, Division of Pediatric Endocrinology, Mattel Children's Hospital and University of California at Los Angeles Coauthor(s): Pinchas Cohen, MD , Director of Research and Training, Professor, Department of Pediatrics, Division of Endocrinology, Mattel Children's Hospital, University of California at Los Angeles Melanie Shim, MD, is a member of the following medical societies:

23. Acromegaly acromegaly Hands - Normal female hand for comparison. For more information see the Online Mendelian Inheritance in Man (OMIM). http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

24. History Of Acromegaly And Gigantism acromegaly and gigantism An historical portrait of a disease Subscribe to History of acromegaly and Gigantism Newsletter To unsubscribe Click here http://www.cladonia.co.uk/acromegaly/

Content Introduction Physical features Acromegaly through the ages Giants: Fact and fiction ... PDP Welcome to the site Recent updates include the addition of pages and information about postcards of giants and the modern equivalent in how the public tends to view giants from the popular press. Hassan Ali, Egyptian Giant. Height 8ft 2in, age 28years. Josef Schippers, the tallest soldier in the world. Height 2.39m. For other information about updates go to the newsletter page , or if you want regular updates you can sign up for the newsletter or subscribe to the RSS feed Subscribe to History of Acromegaly and Gigantism Newsletter To unsubscribe Click here Please note that these web pages are an historical record and appreciation of acromegaly and gigantism and in no way represents current clinical guidelines or state of clinical practice. RSS Feeds Acromegaly and Gigantism D.Bryson@cladonia.co.uk

25. UCLA NEUROSURGERY | Pituitary Disorders & Diseases Describes this condition, its symptoms, diagnosis, and treatment. http://www.pituitary.ucla.edu/Pituitary/PituitaryDis_7.html

Acromegaly (Growth Hormone Secreting Adenoma) PITUITARY TUMOR PROGRAM PITUITARY DIAGNOSES INDEX Acromegaly is a serious systemic condition caused in over 98% of cases by an adenoma of the pituitary gland that secretes excessive growth hormone (GH). The clinical features associated with acromegaly include the effects of GH oversecretion, and in some instances by the tumor compressing and injuring the normal pituitary gland, optic nerves and optic chiasm. Untreated acromegaly results in marked bony and soft tissue changes including an altered facial appearance (frontal bossing, prognathism), enlargement of the hands and feet, sleep apnea, and carpal tunnel syndrome. More serious problems may include accelerated cardiovascular disease, hypertension, diabetes mellitus and an increased risk of colon cancer. If the tumor develops before bone growth is completed in adolescence, gigantism is the result. Because of the serious systemic changes resulting from GH excess, treatment is essential, typically with transsphenoidal surgery Symptoms and signs may include: Soft tissue thickening on the palms of the hand Enlargement of hands (ring size), feet (shoe size) and head (hat size)

26. Acromegaly a CHORUS notecard document about acromegaly http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

27. History Of Acromegaly And Gigantism acromegaly and gigantism An historical portrait of a disease 1.2 Relationship between gigantism, acromegaly and acromegalic gigantism http://www.cladonia.co.uk/acromegaly/chapter01/1-02.html

Content Introduction Physical features Acromegaly through the ages Giants: Fact and fiction ... PDP 1.2 Relationship between gigantism, acromegaly and acromegalic gigantism At first each of these were regarded as separate conditions and acromegalic-gigantism was regarded as a confusion or only recognised as gigantism or acromegaly. The position was clearer by the 1900's as the root cause of the disease, the pituitary adenoma, was found in gigantism and acromegaly alike. The normal sequence of changes from child via puberty to adulthood occur regardless of the tumour and its oversecretion of growth hormone, so what form the conditions takes depends purely on its time of onset. An early onset leads to gigantism with excessive growth of the epiphyses leading to increased height but proportions are kept the same, then as puberty occurs it is followed by progressive acromegalic changes leading to a picture of a giant with acromegalic features - acromegalic gigantism. When onset is later, after epiphyseal closure, only acromegaly results. Lewis, A 1934. Twins at age 15

28. Modern Approaches To Treating Acromegaly Turner And Wass 93 (1) Modern approaches to treating acromegaly H.E. Turner and J.A.H. Wass Department of Endocrinology, Radcliffe Infirmary, Oxford http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

29. EMedicine Health - Understanding Acromegaly Medications, What Is Acromegaly? acromegaly is a growth disorder caused by excessive production of growth hormone (GH) by the pituitary gland. The pituitary gland is a hormoneproducing http://www.emedicinehealth.com/articles/40765-1.asp

Search September 8, 2005 Registration Healthcare Professionals You are in: Acromegaly Understanding Acromegaly Medications What Is Acromegaly? Acromegaly is a growth disorder caused by excessive production of growth hormone (GH) by the pituitary gland. The pituitary gland is a hormone-producing organ at the base of the brain, behind the eyes, and at the middle of the brain between the ears. Children cannot grow to normal height if they do not have enough GH, but too much causes prepubertal children to develop giantism, a condition in which the entire body or any of its parts grow too large. In adults, too much GH causes acromegaly, a disorder in which parts of the body, especially the head, face, hands, and feet, gradually get bigger. GH affects growth by stimulating the formation of other hormones. These hormones are mostly made by the liver in response to GH stimulation and are called somatomedins (somatotropin-mediating hormones or insulinlike growth factors). Last updated: Aug 10, 2005 What Causes Acromegaly?

30. Acromegaly a CHORUS notecard document about acromegaly. acromegaly. excess growth hormone due to eosinophilic adenoma/hyperplasia. osseous enlargement (phalangeal http://chorus.rad.mcw.edu/doc/00971.html

CHORUS Collaborative Hypertext of Radiology Musculoskeletal system About CHORUS Search Feedback acromegaly excess growth hormone due to eosinophilic adenoma /hyperplasia osseous enlargement (phalangeal tufts, vertebrae) flared ends of long bones cystic changes in carpals, femoral trochanters osteoporosis spade-like hand prognathism (elongation of mandible) in few cases sellar enlargement and erosion enlarged paranasal sinuses (esp. frontal): 75% calvarial hyperostosis (esp. inner table) enlarged occipital protuberance vertebrae: posterior scalloping (30%), anterior new bone, loss of disc space heel pad premature osteoarthritis (commonly knees) Yong H. Hahn, MD - 2 February 1995 Last updated 26 May 2004 Related CHORUS documents: posterior vertebral scalloping somatotrophic adenoma heel pad increased skull thickness ... Marfan syndrome Search for related articles: AJR American Journal of Roentgenology PubMed : index to biomedical literature ... Medical College of Wisconsin

31. Acromegaly - MayoClinic.com acromegaly is an uncommon hormonal disorder, caused by the overproduction of growth hormone. It commonly causes signs such as enlarged hands and feet. http://www.mayoclinic.com/invoke.cfm?id=DS00478

32. Neuroendocrine Clinical Center & Pituitary Tumor Center At MGH/Harvard Information on acromegaly, Cushing s disease or syndrome, prolactinoma, chromophobe or nonfunctioning pituitary adenoma, and thyrotroph adenomas. http://pituitary.mgh.harvard.edu/

THE CLINICAL CENTER ABOUT US ATTENDING STAFF OUTPATIENT SERVICES INPATIENT CONSULTATION ... SPEAKERS BUREAU CONDITIONS ACROMEGALY AMENORRHEA CUSHINGS SYNDROME GROWTH HORMONE DISORDERS ... SEARCH The Neuroendocrine Clinical Center - A multidisciplinary approach to patients with pituitary and hypothalamic disorders. Including the Neuroendocrine Center Bulletin; A newsletter with information regarding pituitary tumors. Information on acromegaly, Cushing's disease or syndrome, prolactinoma, chromophobe or nonfunctioning pituitary adenoma, and thyrotroph adenomas NEUROENDOCRINE NEWSLETTER Latest Neuroendocrine Newsletter: Volume 11, Issue 1: Spring/Summer 2005

33. Acromegaly Resources - Neuroendocrine Clinical Center & Pituitary Tumor Center A acromegaly is a hormonal disorder that results when the pituitary gland produces excess Once recognized, acromegaly is treatable in most patients, http://pituitary.mgh.harvard.edu/acromegaly.htm

THE CLINICAL CENTER ABOUT US ATTENDING STAFF OUTPATIENT SERVICES INPATIENT CONSULTATION ... SPEAKERS BUREAU CONDITIONS ACROMEGALY AMENORRHEA CUSHINGS SYNDROME GROWTH HORMONE DISORDERS ... SEARCH May 25, 2005 ACROMEGALY RESOURCES What is Acromegaly? Acromegaly is a hormonal disorder that results when the pituitary gland produces excess growth hormone (GH). It most commonly affects middle-aged adults and can result in serious illness and premature death. Once recognized, acromegaly is treatable in most patients, but because of its slow and often insidious onset, it frequently is not diagnosed correctly. Neuroendocrine Bulletin Archive Update on Acromegaly Journal Club - Colonoscopy in Acromegaly ... Profiles of the Endocrine Clinic A Decade of the Massachusetts General Hospital Neuroendocrine Clinical Center.

34. Acromegaly acromegaly Hands - Normal female hand for comparison. For more information see the Online Mendelian Inheritance in Man (OMIM). Return to Image Index page. http://tray.dermatology.uiowa.edu/Acromeg.htm

Dept. of Dermatology - University of Iowa College of Medicine Acromegaly - Hands - Normal female hand for comparison. For more information see the Online Mendelian Inheritance in Man (OMIM) Return to Image Index page. Return to Image Index page. Return to Dermatology's Home page. September, 1995

35. MedlinePlus Medical Encyclopedia: Acromegaly acromegaly is a chronic metabolic disorder caused by the presence of too much growth There are no known risk factors for acromegaly other than a prior http://www.nlm.nih.gov/medlineplus/ency/article/000321.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Acromegaly Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Endocrine glands Alternative names Return to top Somatotroph adenoma; Growth hormone excess Definition Return to top Acromegaly is a chronic metabolic disorder caused by the presence of too much growth hormone. It results in gradual enlargement of body tissues including the bones of the face, jaw, hands, feet, and skull. Causes, incidence, and risk factors Return to top Acromegaly occurs in about 6 of every 100,000 adults. It is caused by abnormal production of growth hormone after normal growth of the skeleton and other organs is complete. Excessive production of growth hormone in children causes gigantism rather than acromegaly. The cause of the increased hormone secretion is usually a benign tumor of the pituitary gland. The pituitary gland, which is located just below the brain, controls the production and release of several different hormones including growth hormone. There are no known risk factors for acromegaly other than a prior history of a pituitary tumor.

36. SOMAVERT® And Acromegaly Learn about SOMAVERT® (pegvisomant for injection), a medication that can help control acromegaly by helping to lower IGF1 levels. http://www.somavert.com/

FOR PROFESSIONALS PATIENT INFORMATION FULL PRESCRIBING INFO GLOSSARY ... OTHER RESOURCES SOMAVERT (pegvisomant for injection) is a medicine used to treat acromegaly . SOMAVERT decreases the action of growth hormone (GH) and levels of IGF-I (Insulin-like Growth Factors) circulating in the blood. This helps control acromegaly. SOMAVERT is indicated for the treatment of acromegaly in patients who have had an inadequate response to surgery and/or radiation therapy and/or other medical therapies, or for whom these therapies are not appropriate. The goal of treatment is to normalize serum IGF-I levels. While you are on SOMAVERT, your doctor will check your IGF-I levels often. This will show how well your disease is controlled. Your doctor may change your dose to help you achieve normal IGF-I levels Pfizer Bridge Program Learn about patient support that can help improve access to treatment and insurance coverage. Sign Up Now! Get additional information about SOMAVERT and acromegaly. Information for Healthcare Professionals Find product and condition information, downloads, and support.

37. Acromegaly What is acromegaly? Find information about acromegaly symptoms, causes, complications and treatment. http://www.somavert.com/understanding/acromegaly.html

FOR PROFESSIONALS PATIENT INFORMATION FULL PRESCRIBING INFO GLOSSARY ... TREATMENT Sign Up Now! Get additional information about SOMAVERT and acromegaly. What is acromegaly? Acromegaly ( ac-ro-MEG-a-lee ) is a rare hormonal disease that can cause enlargement of the hands, feet, and parts of the face. It can also cause other symptoms. People with acromegaly may also be more likely to get certain diseases, like heart disease or diabetes. The diagnosis may be delayed for years since symptoms show up slowly. What causes acromegaly? Acromegaly occurs when your body makes too much growth hormone (GH) . Most often, the extra GH comes from a tumor in the pituitary gland. The pituitary gland is a small gland at the base of the brain. It produces GH, a hormone that your body needs in order to grow and function properly. Your body uses GH to produce another hormone called insulin-like growth factor I, or IGF-I (I-G-F-wun) When the pituitary gland makes too much GH, your body creates too much IGF-I. And that extra IGF-I can lead to many of the uncomfortable symptoms and health complications of acromegaly.

38. Acromegaly Detailed information on acromegaly, including symptoms, diagnosis, and treatment. http://www.healthsystem.virginia.edu/uvahealth/adult_endocrin/acromegaly.cfm

[ Skip Navigation ] Health System Home For Health Answers Healthcare Professionals ... Advanced Search Health System Search Search for Information People UVa Home Health System News Health System Events (all) Health System Publications ... Making a Gift Topics All About Cancer Blood Disorders Bone Disorders Breast Health Cancer Cardiovascular Disease Dermatology Diabetes Digestive Disorders Endocrinology Environmental Medicine Eye Care Glossary Gynecological Health Infectious Diseases Kidney Disease Men's Health Mental Health Nervous System Disorders Non-Trauma Emergency Oral Health Orthopaedics Otolaryngology Pathology Pediatrics, General Health Prostate Health Radiology Respiratory Disorders Skin Cancer Surgical Care Urology Women's Health UVa Health Topics A to Z FIND A DOCTOR Adrenal Gland Disorders Endocrine Surgery Fertility: Female ... WHY CHOOSE UVA Search This Site Acromegaly What is acromegaly? Acromegaly is the Greek word for "extremities" and "enlargement." When the pituitary gland produces excess growth hormones, this results in excessive growth - called acromegaly. The excessive growth occurs first in the hands and feet, as soft tissue begins to swell. Acromegaly affects mostly middle-aged adults. Untreated, the disease can lead to severe illness and death. What are the symptoms of acromegaly?

39. Endocrine System Diseases acromegaly Addison Disease - Adrenal Gland Diseases - Adrenal Patient s Guide to acromegaly Diagnosis and Therapy DM Cook - The Pituitary Society http://www.mic.ki.se/Diseases/C19.html

search search staff sitemap ABOUT KAROLINSKA INSTITUTET ... print this page Diseases and Disorders Links pertaining to Endocrine System Diseases Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Acromegaly Addison Disease Adrenal Gland Diseases Adrenal Hyperplasia, Congenital ... Wolfram Syndrome Endocrine System Diseases Endocrine Pathology [jpeg archive + comments; EC Klatt] Endocrinology: An integrated approach [Nussey and Whitehead, 1999] - via NLM/NIH Endocrinology information [ED Buckingham] - UTMB (US) Clinical Guidelines for Endocrinologists , and the Power-of-Prevention site (for patients) - Am Assoc of Clin Endocrinologists Patient Factsheets from The Hormone Foundation - (US) The British Society for Paediatric Endocrinology and Diabetes EndocrineWeb.com [for patients, by doctors] Pathophysiology of the Endocrine System [Austgen, Bowen, Rouge] - Colorado State Univ. (US) Tayside Endoweb - Tayside Univ Hospitals, Dundee (UK)

40. Acromegaly - Wikipedia, The Free Encyclopedia acromegaly most commonly affects middleaged adults and can result in serious In over 90 percent of acromegaly patients, the overproduction of GH is http://en.wikipedia.org/wiki/Acromegaly

Wikimedia needs your help in the final days of its fund drive. See our fundraising page Over US$225,000 has been donated since the drive began on 19 August. Thank you for your generosity! Acromegaly From Wikipedia, the free encyclopedia. Rondo Hatton , a famous sufferer of acromegaly whose face was distorted by the disorder. Acromegaly (from Greek akros "high" and megalos "large" - extremities enlargement) is a hormonal disorder that results when the pituitary gland produces excess growth hormone (hGH). Most commonly it is a benign hGH producing tumor derived from a distinct type of cells (somatotrophs) and called pituitary adenoma Acromegaly most commonly affects middle-aged adults and can result in serious illness and premature death. Because of its insidious onset and slow progression, the disease is hard to diagnose in the early stages and is frequently missed for many years. Features that result from high level of hGH or expanding tumor include: Soft tissue swelling of the hands and feet (early sign) Brow and lower jaw protrusion (enlarging jaw and hat size) Enlarging hands (ring size) Enlarging feet (shoe size) Arthritis and carpal tunnel syndrome Teeth spacing increase Heart failure (major medical problem) Compression of the optic chiasm leading to loss of vision in the outer visual fields Diabetes mellitus Hypertension Contents Causes Treatment Surgery Drug therapy ... edit Causes In over 90 percent of acromegaly patients, the overproduction of GH is caused by a benign tumor of the pituitary gland, called an

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 2     21-40 of 108    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20