61. Achondroplasia achondroplasia Word origins etymology dictionary classical Greek Mythology poetry prose literature overview illustration vocubulary lessons reasoning GMAT http://www.consultsos.com/pandora/intr0806.htm

No javascript support Medical Humanities - Visual Fine Arts - Sciences Etymology - Mythology - History - Literature - Poetry Search Links to Key Word Ideas Abnormal Achondroplasia Austri Beth ... Westri Achondroplasia Under current definitions, Achondroplasia is a " birth defect " because the syndrome or complex of signs of this disorder is present at birth. The term achodroplasia is inaccurate because it implies "lack" instead of "abnormal" cartilage. More accurate are the terms chodrodysplasia or chondrodystrophy which imply abnormal cartilage tissue formation and sustenance but these terms apply to many other disorders in addition to achondroplasia. In any case, "achondroplasia" is, for the time being, the most popular term, regardless of its etymology. Classic portrayals. (Velazquez) Extract from a Classical Description by Josef Warkany (Congenital Malformations, Year Book Publishers, 1971) "... A limestone statuette of Chnoum-hotep from about 2700 BC shows a man with a large head, diminutive lower limbs, sort digits and upper limbs, lordosis and good muscular development. This individual had normal intelligence because he was "chief of the Perfumes" or "Head of the Wardrobe. Other achodroplastic dwarfs in Egypt were in charge of pets or jewelry ... Dwarfs and midgets entertained royalty. In this instance, the Mirabell palace harbored many statues of dwarfs, hunchbacks and gnomes (see below).

62. Mendelian: Achondroplasia achondroplasia is defined by recurrent G380R mutations of FGFR3 Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of http://obesitygene.pbrc.edu/cgi-bin/ace/tree/ogm2k?name=Achondroplasia&class=Men

63. Achondroplasia - Wheeless' Textbook Of Orthopaedics growth of endochondral bones is abnormal in achondroplasia and causes Orthopaedic aspects of achondroplasia. J Bone Joint Surg Am 5212851301, http://www.wheelessonline.com/ortho/achondroplasia

Duke Orthopaedics presents Wheeless' Textbook of Orthopaedics Site Index A - Z Search Site by Word Home Contact Us My Account Achondroplasia - See: Pseudoachondroplasia - Discussion: - autosomal dominant disorder; - arises due to a point mutation for the gene encoding a fibroblast growth factor; - it is presumed in these instances that disorder is consequence of mutation and may be related to a mutation in a fibroblast growth factor gene; - growth of endochondral bones is abnormal in achondroplasia and causes disproportionate and rhizomelic shortening of limbs; - since intramembranous ossification is unaffected head is relatively large and the forehead is prominent; - long bones are wide with flaring of the metaphyses; characteristics in infancy: - rhizomelic short limbs and normal trunk height, - midface hypoplasia, and relative mandibular prominence; - maxillary hypoplasia may lead to dental crowding and malocclusion;

64. Achondroplasia- Medco.com achondroplasia is a disorder of bone growth that causes the most common type of dwarfism. http://www.medcohealth.com/medco/consumer/ehealth/ehsarticle.jsp?topicID=HE:Dise

65. Achondroplasia - Swedish Medical Center, Seattle, Washington achondroplasia Swedish Medical Center, Seattle, Washington. http://www.swedish.org/14118.cfm

PDF Version Search Send-to-Friend Health Library Home ... Conditions InBrief Achondroplasia by Rick Alan Definition Causes Risk Factors ... Treatment Definition Achondroplasia is a genetic disorder that causes dwarfism (short stature). It is a disorder in which bone and cartilage do not grow normally. It is the most common cause of dwarfism. This condition leads to patients attaining a full-grown height of less than four feet. The greatest shortening occurs in the humerus (the bone between the shoulder and the elbow) and the femur (the bone between the hip and the knee). There may also be underdevelopment of the face. Achondroplasia is the most common form of inherited disproportionate short stature. It occurs in one in 15,000 to one in 40,000 live births. Causes Achondroplasia is a genetic disorder. It is caused by mutations in the FGFR3 gene that inhibits growth of cartilage at the growth plate. The result is that the growth of bones, which normally occurs in the cartilage of the growth plate, is slowed. This leads to shorter bones, abnormally shaped bones, and shorter stature. The gene for achondroplasia can be passed from one generation to the next. If a parent has the disorder there is a 50% chance of passing the gene for achondroplasia on to offspring (Autosomal Dominant Inheritance). In most cases of achondroplasia (80-90%), it more commonly is the result of a spontaneous mutation (a sudden genetic defect) that occurs in the developing embryo.

66. Achondroplasia - International Center For Limb Lengthening - Rubin Institute For achondroplasia Sinai Hospital Maryland. Find a Physician, achondroplasia. LifeBridge Health Quick Links, LifeBridge Health ..Community Calendar . http://www.lifebridgehealth.org/245.cfm

Achondroplasia LifeBridge Health Quick Links LifeBridge Health ..Community Calendar ..Giving Opportunities ..Careers at LifeBridge ..Medical Services ..News ..Volunteering ..Health Buzz ..Site Map ..Site Search ..Contact LifeBridge Health Sinai Hospital ..Directions to Sinai Hospital ..Children's Hospital at Sinai ..Graduate Medical Education ..VSP ..Centers Of Excellence -Medical Services- ..Addictions Recovery Program (SHARP) ..Anesthesia ..CyberKnife� Center ..Emergency Medicine (ER-7) ..Heart Center ..International Center for Limb Lengthening ..Krieger Eye Institute ..Medicine ..Oral Surgery and Dentistry ..Otolaryngology ..Pathology ..Psychiatry ..Radiation Oncology ..Radiology ..Rehabilitation Center ..Rubin Institute for Advanced Orthopedics ..Sleep Center ..Spine Center ..Stroke Center ..Surgery ..Urology ..Volunteering ..Women's Services ..Nursing at Sinai ..Sinai Auxiliary ..Patient E-Cards ..Sinai Gift Shop ..Contact Sinai Northwest Hospital Center ..Directions ..Centers of Excellence Medical Services ..Allergy and Immunology ..Anesthesia ..Breast and Bone Health ..ER-7 Emergency Center ..Family Medicine ..General Surgery ..Geriatric Program ..Gynecology ..Gynecologic Oncology ..Hand Center ..Internal Medicine ..Joint Center ..Medicine ..Oncology ..Outpatient Surgery Center ..Psychiatry ..Psychiatric Services ..Radiation Oncology ..Radiology ..Sleep Center ..Spine Center ..Surgery ..Urology ..Wound Service ..Volunteering ..Northwest E-Cards ..Contact Northwest Levindale ..Levindale Auxiliary ..Visitor Information ..Driving Directions ..Nursing Home

67. Dwarfism: Achondroplasia And Hypochondroplasia - International Center For Limb L Dwarfism achondroplasia and Hypochondroplasia Sinai Hospital Maryland. http://www.lifebridgehealth.org/2187.cfm

Dwarfism: Achondroplasia and Hypochondroplasia LifeBridge Health Quick Links LifeBridge Health ..Community Calendar ..Giving Opportunities ..Careers at LifeBridge ..Medical Services ..News ..Volunteering ..Health Buzz ..Site Map ..Site Search ..Contact LifeBridge Health Sinai Hospital ..Directions to Sinai Hospital ..Children's Hospital at Sinai ..Graduate Medical Education ..VSP ..Centers Of Excellence -Medical Services- ..Addictions Recovery Program (SHARP) ..Anesthesia ..CyberKnife� Center ..Emergency Medicine (ER-7) ..Heart Center ..International Center for Limb Lengthening ..Krieger Eye Institute ..Medicine ..Oral Surgery and Dentistry ..Otolaryngology ..Pathology ..Psychiatry ..Radiation Oncology ..Radiology ..Rehabilitation Center ..Rubin Institute for Advanced Orthopedics ..Sleep Center ..Spine Center ..Stroke Center ..Surgery ..Urology ..Volunteering ..Women's Services ..Nursing at Sinai ..Sinai Auxiliary ..Patient E-Cards ..Sinai Gift Shop ..Contact Sinai Northwest Hospital Center ..Directions ..Centers of Excellence Medical Services ..Allergy and Immunology ..Anesthesia ..Breast and Bone Health ..ER-7 Emergency Center ..Family Medicine ..General Surgery ..Geriatric Program ..Gynecology ..Gynecologic Oncology ..Hand Center ..Internal Medicine ..Joint Center ..Medicine ..Oncology ..Outpatient Surgery Center ..Psychiatry ..Psychiatric Services ..Radiation Oncology ..Radiology ..Sleep Center ..Spine Center ..Surgery ..Urology ..Wound Service ..Volunteering ..Northwest E-Cards ..Contact Northwest Levindale ..Levindale Auxiliary ..Visitor Information

68. Indian Pediatrics - Editorial achondroplasia is the most common chondrodysplasia occuring with the frequency of 1 in Children with achondroplasia have short stature, megalencephaly, http://www.indianpediatrics.net/july2002/july-694-695.htm

Home Past Issue About IP About IAP ... Subscription Images in Clinical Practice Indian Pediatrics 2002; 39:694-695 Achondroplasia A 4-year-old boy born to non-consanguineous parents was diagnosed to have achondroplasia by antenatal ultrasound. At birth, clinical examination revealed a term baby with large head, prominent forehead, depressed nasal bridge and short upper and lower limbs. His birth weight was 3 kg, length 47 cm and head circumference 40 cm. He also had mild hypotonia and short thoracic cage at birth. He had been followed up with serial head circumference measurements during infancy ( Fig.1 ). At the age of 8 months he had rapidly increasing head circumference with wide and bulging anterior fontanel. A cranial ultrasound performed at that time revealed dilated lateral and third ventricles. A ventriculo peritoneal shunt was done at 8-months of age. Now, at the age of 4 years, his height is 75 cm (height age 1 year) and head circumference is 52 cm. His mental development and intelligence is normal for his age. Fig. 1. Photograph at 3-months of age showing large head, depressed nasal bridge, prominent forehead and short limbs.

69. Achondroplasia Information and links on achondroplasia. achondroplasia achondroplasia. By the Human Growth Foundation. http://www.doctorpage.com/findit/Diseases_and_Conditions/Achondroplasia/

doctorpage Diseases and Conditions Achondroplasia Displaying listings 1-6 Achondroplasia Achondroplasia. By the Human Growth Foundation. http://www2.shore.net/~dkennedy/dwarfism_hgfachon.html Achondroplasia http://www.sbu.ac.uk/~dirt/museum/p4-1521.html Achondroplasia  http://www.mssc.edu/biology/B305/GTS/fs97/achond/achond.htm Achondroplasia  http://www.med.jhu.edu/Greenberg.Center/achon.htm Achondroplasia  http://med-aapos.bu.edu/PediRef/Achondroplasia.html Yahoo! - Health:Diseases and Conditions:Achondroplasia  http://www.yahoo.com/text/Health/Diseases_and_Conditions/Achondroplasia/ Listings 1-6 of 6 displayed. Add a Site to This Page Get A Free Site Find Physicians Cosmetic Surgery ... Findit Try this search on... HotBot Infoseek AltaVista Excite ... Metacrawler doctor page .com

70. Genes And You - Genetic Disorders - Achondroplasia The pattern of inheritance for achondroplasia is autosomal dominant. Where one parent has achondroplasia, there is a 50% (1 in 2) chance of each and every http://www.gig.org.uk/genesandyou_achondroplasia.htm

Genetic Interest Group - Working to benefit all people affected by genetic disorders Home Latest News Publications Press ... Site Map How helpful is our site? Comment: Your email: Add to mailing list: Who are you? Choose.. Student Teacher Medical Scientist/Research Member of GIG Patient Family Member Carer Press Other You are here: Education Genes and You Contents Achondroplasia Achondroplasia WHAT IS ACHONDROPLASIA? Achondroplasia (pronounced ay-kon-dro-play-zha) is a genetic condition in which a person is of very short stature because of restricted growth of bones and cartilage. Some conditions which cause restricted growth affect the whole body equally, but the growth of a person with Achondroplasia is 'disproportionate' (i.e. unequal) because growth is most restricted in the long bones of the legs and arms, while the trunk is near to average size. HOW IS ACHONDROPLASIA PASSED ON? The pattern of inheritance for Achondroplasia is autosomal dominant. Where one parent has Achondroplasia, there is a 50% (1 in 2) chance of each and every child being affected. If both parents have Achondroplasia, each and every child has a 50% (1 in 2) chance of having Achondroplasia and a 25% (1 in 4) chance of being unaffected. There is also a 25% (1 in 4) chance of the baby inheriting the Achondroplasia gene from both parents, in which case it will be very severely affected and die soon after birth. However, most people with the condition have no family history of Achondroplasia. They are probably affected because of a spontaneous genetic mutation which took place in the egg or sperm before fertilisation.

71. University Of Chicago Comer Children's Hospital: Achondroplasia Detailed information on achondroplasia, including causes, symptoms, diagnosis, and treatment. http://www.uchicagokidshospital.org/online-library/content=P01938

@import "/css/style.css"; @import "/css/gs.css"; Home Contact Us Pediatric Specialties Find A Physician ... Growth Problems Achondroplasia What is achondroplasia? Achondroplasia is a genetic (inherited) bone disorder that occurs in one in 25,000 live births. Achondroplasia is the most common type of dwarfism, in which the child's arms and legs are short in proportion to body length. Further, the head is often large and the trunk is normal size. The average height of adult males with achondroplasia is 52 inches (or 4 feet, 4 inches). The average height of adult females with achondroplasia is 49 inches (or 4 feet, 1 inch). What causes achondroplasia? Achondroplasia is inherited by an autosomal dominant gene that causes abnormal cartilage formation. Autosomal dominant inheritance means that the gene is located on one of the autosomes (chromosome pairs 1 through 22). This means that males and females are equally affected. Dominant means that only one gene is necessary to have the trait. When a parent has a dominant trait, there is a 50 percent chance that any child they have will also inherit the trait. So, in some cases, the child inherits the achondroplasia from a parent with achondroplasia. The majority of achondroplasia cases (80 percent), however, are the result of a new mutation in the family - the parents are of average height and do not have the abnormal gene. As mentioned, persons with achondroplasia have a 50 percent chance to pass the gene to a child, resulting in the condition. If both parents have achondroplasia, with each pregnancy, there is a 50 percent chance to have a child with achondroplasia, a 25 percent chance that the child will not inherit the gene and be of average height, and a 25 percent chance that the child will inherit one abnormal gene from each parent, which can lead to severe skeletal problems that often result in early death.

72. BSPED | Patients | Nick's Notes | Achondroplasia achondroplasia is a genetic condition which primarily involves the skeleton and so However, in achondroplasia about threequarters of affected people http://www.bsped.org.uk/patients/nick/ACHONDRO.htm

Home Professionals Patients Members ... Resources Nick's Notes Achondroplasia Congenital Adrenal Hyperplasia (21 hydroxylase) Congenital Adrenal Hyperplasia (11 hydroxylase) Congenital Adrenal Hyperplasia - treatment in pregnancy ... Nick's Notes Nick's Notes ACHONDROPLASIA Achondroplasia is a genetic condition which primarily involves the skeleton and so restricts growth. It is rare, affecting only about 1 in 20,000 people. Cause: Physical features: Treatment: There is no specific treatment but it is desirable to monitor the progress of affected children to offer support and to detect early the occurrence of any complications. Most children cope remarkably well with the problems arising from their short stature and most schools are helpful. Attempts to increase final height with growth hormone treatment have not been successful but in recent years surgical bone-lengthening procedures have been developed in several centres. These require major surgery, which is generally done in at least two operations, and the wearing of heavy and uncomfortable expandable bone braces for many months, typically about 18 months. If all goes well a really significant gain in height can be achieved, about 10-12in (25-30cm). Clearly such surgery is a major undertaking for both the child and the family and the decision to go ahead has to be most carefully considered. Outlook: Most people with achondroplasia cope extraordinarily well with the physical difficulties and lead successful and fulfilled lives. Many have distinguished themselves in various fields. The Restricted Growth Association (103 St Thomas Avenue, West Town, Hayling Island, Hants PO11 OEU) is an important source of help on this and other related conditions. NDB

73. Achondroplasia Notes for physicians on achondroplasia, covering diagnosis, clinical description, differential diagnosis, management, molecular genetics and genetic http://omni.ac.uk/browse/mesh/D000130.html

low graphics Achondroplasia broader: Genetic Diseases, Inborn other: Adrenal Hyperplasia, Congenital Ataxia Telangiectasia Chromosome Disorders Cystic Fibrosis ... GeneReviews : achondroplasia Notes for physicians on achondroplasia, covering diagnosis, clinical description, differential diagnosis, management, molecular genetics and genetic counselling. Revised during March 2001, this resource forms part of GeneReviews (formerly GeneClinics profile), a peer-reviewed clinical genetic information resource that is funded by the US National Institutes of Health (NIH) and produced by the University of Washington, Seattle. This resource contains a summary and bibliographical references of the review. Last updated in July 2003. Achondroplasia / genetics Last modified: 02 Sep 2005

74. Achondroplasia UK - Patient UK achondroplasia UK Patient UK. A directory of UK health, disease, illness and related medical websites that provide patient information. http://www.patient.co.uk/showdoc/26740463/

Achondroplasia.co.uk Orchard Mill Lane Timsbury BATH Tel: 01761 471 257 Web: www.achondroplasia.co.uk Best time to telephone: normal working hours Achondroplasia is the most common form of short limb dwarfism. Achonodroplasia.co.uk has been set up to provide support and information to those affected by the condition and those caring for them - both parents and professionals. The site includes in depth information on the condition, its diagnosis and health supervision from birth to early adulthood. There is a discussion forum and links to other sources of information are included. Visit the site or contact the above address for more details. Checked: January 2005 Sponsored links and adverts Patient UK has no control of the content of the following links. Inclusion does not imply endorsement by Patient UK. Health Related Books From Amazon - browse hundreds of books on health and disease. Also, worth a look... Related pages in Patient UK See also Restricted Growth Association Patient Plus Achondroplasia Other - Useful resources Pictures, diagrams, photos, images, etc.

75. Achondroplasia - Patient UK achondroplasia Patient UK. A directory of UK health, disease, illness and related medical websites that provide patient information. http://www.patient.co.uk/showdoc/40001123/

PatientPlus articles are written for doctors and so the language can be technical. However, some people find that they add depth to the articles found in the other sections of this website which are written for non-medical people. Achondroplasia This is a rare inherited disorder of bone growth (commonest type of dwarfism ). Incidence and prevalence are not clear as until recently, any case of excessively short limbs was diagnosed as achondroplasia. The disorder is inherited in Autosomal dominant manner with complete penetrance - but over 80% of cases are spontaneous mutations. Incidence increases with paternal age. Skeletal dysplasia is caused by a non- collagen mutation in fibroblast growth factor receptor 3; - epiphyseal growth cartilage fails but with normal bone formation and repair. Presentation In homozygous form condition is severe and lethal. At birth or within first year of life with disparity between large skull, normal length trunk and short arms and legs. Fingertips may only come down to the iliac crest.

76. Achondroplasia xray2000 Nick\ s Website 3000+ xray images and Info. http://www.e-radiography.net/radpath/a/achondroplasia.htm

Achondroplasia Definition achondroplasty; osteosclerosis congenita; Parrot's disease (2); a type of chondrodystrophy characterized by an abnormality of conversion of cartilage into bone, predominantly affecting the epiphyses of long bones in which epiphysial growth is retarded and ceases early, resulting in dwarfism apparent at birth, with short extremities, but normal trunk; the head is frequently enlarged, with flattened nose, due to midfacial hypoplasia; autosomal dominant inheritance. Radiographic Appearance - Radiology: Skeletal X-Ray Short bowed wide bones with expanded ends Increased bone density Characteristic cupping of metaphases Incomplete glenoid fossa and acetabulum Wide joint spaces Pathology So what is the cause of Achondroplasia? A chemical change within a single gene causes Achondroplasia. It is not caused from anything the parents have done during pregnancy, the condition has started from a autosomal dominate condition. What this means is that a new mutation or genetic change has started during conception. The condition may also be passed on from one generation to the next; nine out of ten children born with this condition have average-sized parents. If one parent has Achondroplasia there is a 50% chance there child will inherit a single copy of the gene, if both parents have Achondroplasia there is a 25% chance the child will have a double dominant gene and a 75% chance of a single Achondroplasia gene: The gene is called FIBROBLAST GROWTH FACTOR RECEPTOR

77. RGA achondroplasia is a rare, genetic condition, but one of the most common types achondroplasia is mainly a physical condition with affected people having http://www.restrictedgrowth.co.uk/achondroplasia.php

Restricted Growth Association Navigation Home Conditions Membership News ... Ellis-van Creveld syndrome Achondroplasia Achondroplasia is a rare, genetic condition, but one of the most common types of restricted growth with disproportionate short stature. Achondroplasia is mainly a physical condition with affected people having normal intelligence. Many practical difficulties can be overcome with a little imagination and there is no reason why someone with achondroplasia should not participate in most activities. It is important that the person themselves is able to find their own limits and boundaries and that these are not imposed by society. Achondroplasia literally means 'no cartilage growth,' but in reality it refers to poor bone growth resulting in shortened limbs. The tissues around the limbs are not affected and continue to grow leading to bulky arms and legs. Growth charts designed specifically for children with achondroplasia should be used to monitor growth. People with achondroplasia have a range of characteristics including: A near normal trunk length with shorter arms and legs A large head with prominent forehead and flattened bridge of the nose An increased curvature of the lower spine (lumbar lordosis) Bowing of the lower legs Possible crowded teeth Short, broad feet and hands with separation between middle and ring fingers (the 'trident' hand)

78. Achondroplasia - Definition Of Achondroplasia By The Free Online Dictionary, The Definition of achondroplasia in the Online Dictionary. Meaning of achondroplasia. What does achondroplasia mean? achondroplasia synonyms, achondroplasia http://www.thefreedictionary.com/achondroplasia

Domain='thefreedictionary.com' word='achondroplasia' Your help is needed: American Red Cross The Salvation Army join mailing list webmaster tools Word (phrase): Word Starts with Ends with Definition subscription: Dictionary/ thesaurus Computing dictionary Medical dictionary Legal dictionary Financial dictionary Acronyms Columbia encyclopedia Wikipedia encyclopedia Hutchinson encyclopedia achondroplasia Also found in: Medical Wikipedia 0.01 sec. Page tools Printer friendly Cite / link Email Feedback a·chon·dro·pla·sia -k n dr -pl zh , -zh n. Improper development of cartilage at the ends of the long bones, resulting in a form of congenital dwarfism. a·chon dro·plas tic (-pl s t k) adj. Thesaurus Legend: Synonyms Related Words Antonyms Noun achondroplasia - an inherited skeletal disorder beginning before birth; cartilage is converted to bone resulting in dwarfism achondroplasty chondrodystrophy osteosclerosis congenita congenital disease ... inherited disorder - a disease or disorder that is inherited genetically Mentioned in References in classic literature No references found No references found Dictionary/thesaurus browser Full browser Achoerodus Achoerodus gouldii acholia Acholous ... achondritic achondroplasia achondroplastic achondroplasty Achras Achras zapota ... achondrogenesis achondroplasia achondroplastic achondroplastic dwarfism achondroplastic dwarfism achondroplasty ... Achour, Habib

79. Achondroplasia achondroplasia is a disorder of bone growth that causes the most common type of . http://www.lifespan.org/ADAM/English/HIE/001577.htm

Careers at Lifespan Volunteer your time Other ways to give Lifespan's A - Z Health Information Library Injury Disease Nutrition Poison ... Prevention Achondroplasia Definition Achondroplasia is a disorder of bone growth that causes the most common type of dwarfism Causes Achondroplasia is an inherited disorder of bone growth. It is one of the group of disorders that are collectively called chondrodystrophies or osteochondrodysplasias. The disorder causes a type of dwarfism that is recognized by its characteristic normal to large-sized head, shortened arms and legs (especially the upper arm and thigh), a normal-sized trunk, and waddling gait . Achondroplasia is the most common type of dwarfism. Achondroplasia can be inherited as an autosomal dominant trait, which means that if a child gets the defective gene from one parent, he or she will have the disorder. However, the majority of cases, approximately 80%, appear as spontaneous mutations. This means that two patients without achondroplasia may give birth to a baby with achondroplasia. If one parent has achondroplasia, the infant has a 50% chance of inheriting the disorder. If both parents have the condition, the infant's chances of being affected increase to 75%. Review Date: 2/12/2003 Reviewed By: Andrew L. Chen, M.D., M.S., Department of Orthopaedic Surgery, Hospital for Joint Diseases, New York, NY. Review provided by VeriMed Healthcare Network.

80. University Of Miami School Of Medicine - Glossary - Achondroplasia The average height of an adult with achondroplasia is 131 cm (52 inches, or 4 foot 4) in achondroplasia is the most common cause of short stature with http://www.med.miami.edu/glossary/art.asp?articlekey=256

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