41. MedlinePlus Medical Encyclopedia: Factor V Deficiency Provides brief information about this inherited bleeding disorder, which is similar to hemophilia. Includes causes, symptoms, and prognosis. http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Factor V deficiency Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Blood clot formation Blood clots Alternative names Return to top Parahemophilia; Owren's disease Definition Return to top Factor V deficiency is an inherited abnormal blood coagulation disorder caused by a deficiency of the plasma protein Factor V. Causes, incidence, and risk factors Return to top Normal blood coagulation is a complex process involving as many as 20 different plasma proteins, which are known as blood coagulation factors. A series of complex chemical reactions using these factors takes place very rapidly to form an insoluble protein called fibrin that stops bleeding. In this disorder, bleeding ranges from mild to severe. When certain coagulation factors are deficient or missing, the chain reaction does not take place normally. Factor V is rare, and can be caused by inheriting a defective Factor V gene or by acquiring an antibody that interferes with normal Factor V function. An inhibitor of Factor V can be acquired after giving birth, after surgery, with automimmune diseases and certain cancers, in patients being treated wtih a certain type of fibrin glue, and from unknown sources.

42. Octagen Corporation | Developing New Therapies For Hemophilia Privately held company developing therapies for hemophilia and other genetic disorders, using recombinant Factor VIII and gene therapy. Includes clinical trial status, licensing, corporate profile and contacts in Bala Cynwyd, Pennsylvania. http://www.octagen.com/

Octagen Corporation is a privately held biopharmaceutical company whose mission is to develop and commercialize improved therapies for hemophilia and other genetic disorders. Legal Notice

43. Tunnel For information in English, please go to this site Swedish hemophilia Society Nepal our twinning partner. This site works best with Internet Explorer. http://www.xpress.se/fbis/english.html

For information in English, please go to this site: Swedish Hemophilia Society Nepal - our twinning partner This site works best with Internet Explorer. Download Explorer here

44. A Little Web Page About Me... Personal information, photos, growing up with hemophilia and favourite links. http://hometown.aol.com/jscott420/JScott420.html

htmlAdWH('93212823', '728', '90'); Main Other Disabilities CNN, MSNBC, ... FOX NEWS Growing up and living with Hemophilia... I am 26 years old, living with severe Hemophilia A. As a kid, dealing with hemophilia and/or other types of bleeding disorders is a little bit more difficult than when you get older. When I was a young kid, I had to learn what my body could handle without causing internal bleeding. I wanted to play football, I wanted to wrestle, I wanted to jump on our trampoline with my older sister and cousins.. :) just had to learn the hard way in some of those cases.. well, this is me.. just chillin gettin ready to head out for a bit.. I'm a very romantic guy, always out to please my lady.. ;) My main interests are camping, rafting, hiking, rock climbing, boating, playing the lastest video games, fixin up my car, checkin out the stars at night when its clear. I am a counselor for a youth camp for kids with bleeding disorders, helping kids have a chance to experience activities that they otherwise would not have the opportunity to fully participate in. E-mail me for additional information about camp. Up Down Top Bottom Links I Recommend BAYER EQUALS DEATH.COM

45. Hemophilia hemophilia resources, support groups, clinics with genetic counselors and geneticists. http://www.kumc.edu/gec/support/hemophil.html

Hemophilia National Hemophilia Foundation 110 Greene St, Room 303 New York, NY 10012 Phone: (800) 424-2634 or (212) 219-8180 Contact: Cathy Crosby Fax: (212) 966-9247 Web site: www.hemophilia.org World Federation of Hemophilia 1310 Greene Avenue, Suite 500 Montreal, Canada H3Z 2B2 Phone: (514) 933-7944 Fax: (514) 933-8916 E-mail: wfh@wfh.org Web Site: www.wfh.org/ World Federation Links International Resources: Association Française des Hémophiles , France Association for Persons with Hemophilia (Russia) Belgian Haemophilia Society Canadian Hemophilia Society Danmarks Bløderforening , Denmark The German Haemophilia Association The Haemophilia Society , United Kingdom Haemophilia Foundation Australia Icelandic Haemophilia Society Italian Hemophilia Foundation Federazione delle Associazioni Emofilici - ONLUS Netherlands Hemophilia Society Norwegian Haemophilia Society Spanish Hemophilia Federation / Federación Española de Hemofilia South African Haemophilia Foundation ... Swiss Hemophilia Society Other information Hemophilia-Related Organizations Hemophilia Home Page AEGIS (AIDS Education Global Information System) Marty Howard's HIV/AIDS site ... Hemophilia , Iowa City, Iowa Hemophilia Support Group Truman Medical Center, Kansas City, MO 64108, 816.234.3277

46. FAMOHIO Hemophilia Home Page Promotes the sharing of knowledge, experiences and concerns among those individuals with hemophilia and related bleeding disorders. http://www.famohio.org/

Welcome To FAMOHIO ! FAMOHIO promotes the sharing of knowledge, experiences and concerns among those individuals with hemophilia and related bleeding disorders. FAMOHIO is a registered 501(c)(3) charity. Click on the FAMOHIO logo to enter the main site or select one of the shortcuts below. Visitors To FAMOHIO Portions of the FAMOHIO web site were last updated on August 30, 2005 FAMOHIO 2006 will be August 4 - 6 in Columbus, Ohio. FAMOHIO, Inc

47. Care For Life Provides products and therapies designed to treat hemophilia and other bleeding disorders. http://www.careforlife.com/

Post 9/11 Travel Form Because of heightened airport security, we have drafted a letter to help you in avoiding unnecessary inconveniences. Print this 2-page document prior to traveling. We take your privacy seriously! Our Patient Confidentiality statement shows you exactly how we protect you and your information. Are you a mental health care provider? Learn what Care for Life can offer you and your patients! Factor Mat These effective learning tools were developed for you by Care for Life's experienced clinical staff. Ask the Pharmacist Bleeding Disorders Infectious Disease States MentalHealth ... HIPPAA Privacy Notice To learn more about Care for Life¹s JCAHO accreditation, click here

48. Hemophilia - Medical Information On Treatment Options, And Links To Other Sites. Information on hemophilia, diagnosis, symptoms, treatment issues, and patient information. http://www.mdsa.bc.ca/hemophilia.html

REFINE YOUR SEARCH hemophilia hemophilia Haemophilia or hemophilia is the name of any of several hereditary genetic illnesses that impair the body's ability to control bleeding. Genetic deficiencies (or, very rarely, an autoimmune disorder) cause lowered plasma clotting factor activity so as to compromise blood-clotting; when a blood vessel is injured, a scab will not form and the vessel can continue to bleed excessively for a very long period of time. The bleeding can be external, if the skin is broken by a scrape, cut or abrasion, or it can be internal, into muscles, joints or hollow organs. Causes Haemophilia is generally caused by a mutation affecting the genes encoding one of the clotting factors. The genes for the most common form, Haemophilia A , are located on the X chromosome, so haemophilia is usually a sex-linked trait. Women have two X-chromosomes, whereas men have one X and one Y chromosome. Since the mutations causing the disease are recessive, a woman carrying the defect on one of her X-chromosomes will not be affected by it, as the equivalent allele on her other chromosome would express itself to produce the necessary clotting factors. However the Y-chromosome in men has no gene for factors VIII or IX. If the gene responsible for blood clotting on a man's X-chromosome is deficient there is no equivalent on the Y-chromosome, so the deficient gene is not masked by the dominant allele and he will develop the illness. Since a man receives his single X-chromosome from his mother, the son of a healthy woman silently carrying the deficient gene will have a 50% chance of inheriting that gene from her and with it the disease. In contrast, for a woman to inherit the disease, she must receive two deficient X-chromosomes, one from her mother and the other from her father (who must therefore be a haemophiliac himself). Hence haemophilia is far more common among men than women. However, haemophiliac daughters are more common than they once were, as improved treatment for haemophilia means that more men survive to adulthood and become parents. Adult women with haemophilia menstruate periodically, so they must take clotting factor to survive.

49. NHF | MASAC Recommendation #130 | Use Of Therapeutic Ultrasound To Aid In Blood Recommendations approved by the Medical and Scientific Advisory Council (MASAC) of the National hemophilia Foundation regarding the use of therapeutic ultrasound to aid in blood resorption http://www.hemophilia.org/research/masac/masac130.htm

MASAC Document #130 MASAC Recommendation Regarding the Use of Therapeutic Ultrasound to Aid in Blood Resorption The following recommendation was approved by the Medical and Scientific Advisory Council (MASAC) of the National Hemophilia Foundation on March 24, 2002, and adopted by the NHF Board of Directors on April 15, 2002. Background Therapeutic ultrasound is a physical modality in which nonionizing radiation, in the form of sound, is transferred to the body's tissues and absorbed as heat. It is applied at frequencies of 1.0 MHz and 3.0 MHz and is the most commonly used deep-heating modality, capable of reaching depths of five centimeters and more below body surface. Ultrasound, like short-wave diathermy, may be applied in the continuous format or in pulsed waves to apply therapeutic heat and nonthermal effects. One intended use of ultrasound is to achieve the benefits of deep heating. As with other methods of therapeutic heat, the use of ultrasound in this capacity is thought to increase collagen extensibility, circulation, pain threshold, enzymatic activity, cell membrane permeability, and nerve conduction velocity. Conversely, use of ultrasound in the pulsed mode has been proposed to have the nonthermal effects of acoustic streaming, cavitation, and micromassage caused by the mechanical vibration of the sound waves. Nonthermal benefits are reported to increase cellular activity and protein synthesis and to decrease edema. Until recently, ultrasound was applied clinically in hopes of gaining the above benefits, based on a limited theoretical basis. However, in a recent review published by Baker et al. in

50. Royal Hemophilia Pedigree A Pedigree of hemophilia in the Royal Families of Europe World Federation of hemophilia National hemophilia Foundation hemophilia Home Page http://www.people.virginia.edu/~rjh9u/roylhema.html

A Pedigree of Hemophilia in the Royal Families of Europe Selected members of the pedigree I-1 = King George III III-1 and III-2 = Prince Albert and Queen Victoria IV-5 and IV-6 = Alice of Hesse and Ludwig IV of Hesse V-13 and V-14 = Alix and Nicholas II (Tsar of Russia) VI-16 = Alexei VIII-1 = Prince Charles A Case Study of Hemophilia An Alternate Diagnosis World Federation of Hemophilia National Hemophilia Foundation ... The British Monarchy This document maintained by Robert J. Huskey Last updated on August 11, 1998.

51. FACTOR FOUNDATION HOME Locating financial support for those dealing with hemophilia and related bleeding disorders. Membership. http://www.factorfoundation.org/

Factor Foundation Of America Grant Award Announcement. The Factor Foundation of America is privileged to announce 2005 grant recipients... Dave's Memory Revs On, postponed by rain. Event rescheduled for July 16th at Moroso MotorSports Park, please click here for more info! Click here to view the audio and video of the Hemophilia Awareness Month PSA. FAQS Latest in Bleeding Disorders

52. Hemophilia Of Iowa, Inc What is hemophilia? Chapter Profile Social Events and Activities The BloodLink Contact Information Other Important Links http://www.hemophiliaofiowa.org/

Home What is Hemophilia? Chapter Profile Social Events and Activities ... Other Important Links Welcome!!! Your input is appreciated. Please e-mail your questions or comments to the Web Page Administrator. This page is hosted by LIGHTHOUSE COMMUNICATIONS, INC

53. Welcome To The Nevada Childhood Cancer Foundation Organization provides social, emotional, psychological and educational support for families of children with critical illnesses including HIV/AIDS, hemophilia, sickle cell anemia, cancer, and immunological and renal diseases. http://nvccf.org

The Nevada Childhood Cancer Foundation, working side-by-side with the medical team, provides social, emotional, educational and psychological support services to families of all children who are diagnosed with life threatening or critical illnesses such as cancer, HIV/AIDS, sickle cell anemia and other immunological diseases. 12th Annual ‘Profiles Of Courage’ Dinner and Auction will be held on October 29, 2005 at the Mirage Hotel Casino Ballroom. Call now and reserve your table 702-735-8434. MORE DETAILS CLICK HERE Home Board of Directors Camp Cartwheel ... Bravery Hearts Profiles of Courage Beads NCCF is A Non-Profit 501 (C) 3 Corporation © 2004 NCCF Site Maintained by Original Design and Hosting by Bizwala Amazing photography courtesy of ModePhoto High quality photos available for purchase from ModePhoto by clicking here Sales of photos benefit the Nevada Childhood Cancer Foundation.

54. How To Deal With Hemophilia If a person has hemophilia, his blood doesn t clot as it should. What does that mean? Find out in this article for kids. http://kidshealth.org/kid/health_problems/blood/hemophilia.html

KidsHealth Kids Kids' Health Problems Blood Hemophilia (say: hee-muh- fih -lee-uh) is a genetic disorder in which a person's blood does not clot properly. "Hemo" means blood and "philia" means a tendency toward. A person who has hemophilia has a tendency to bleed excessively. Think of the last time you had a cut or scrape. When the bleeding stops on its own, you're seeing clotting in action. A Bit About Blood If your blood is clotting normally, your body naturally protects itself. Platelets , which are "sticky cells," go to where the bleeding occurs and cover the hole, plugging it up. This is the first step in the clotting process. When the platelets plug the hole, they release chemicals that attract more sticky platelets and also activate various clotting factors, which are proteins in the blood. These proteins mix with the platelets to form fibers, which make the clot stronger and stop the bleeding. Our bodies have 12 clotting factors that work together to make fibrinogen (say: fy- brih -nuh-jun), the substance that makes the fibers. Trouble begins if the body is missing one of these factors.

55. TSE - Transmissible Spongiform Encephalopathies List of all transmissible spongiform encephalopathies affecting humans. http://www.hemophilia.ca/en/4.2.php

TSE - Transmissible Spongiform Encephalopathies TSE - Transmissible Spongiform Encephalopathies World Federation of Hemophilia Statement on the Export of U.K.-Source Plasma Products from 1980 to 2001 October 1, 2004 World Federation of Hemophilia (WFH) TSE Task Force bulletin on vCJD risk in U.K.-sourced plasma products September 21, 2004 WFH Statement on Second vCJD Transfusion-Transmission Case Wednesday, July 28, 2004 WFH Statement on Transmission of vCJD by Transfusion December 19, 2003

56. Hemophilia For guys with a rare bleeding disorder called hemophilia, minor cuts and bruises can be a big deal. The good news is that it s a lot easier to control now http://kidshealth.org/teen/diseases_conditions/blood/hemophilia.html

KidsHealth Teens Blood Disorders If you ride a skateboard or play a sport, you probably know about bruises and banged-up knees and elbows. But for guys with a rare bleeding disorder called hemophilia (pronounced: hee-muh- fih -lee-uh), minor cuts and bruises can be a big deal. What Is Hemophilia? Hemophilia is a disease that prevents a person's blood from clotting properly, which means that the person bleeds more than a person without hemophilia does. It's a genetic disorder, which means it's the result of a change in genes that's either inherited (passed on from parent to child) or that happens during development in the womb. "Hemo" means blood and "philia" means a tendency toward. A person who has hemophilia has a tendency to bleed excessively. Hemophilia affects mostly boys, although it's very rare: Only about one in every 8,000 boys is born with hemophilia. The disease can affect people of any race or nationality. For most people, when they get a cut, the body naturally protects itself. Sticky cells in the blood called platelets go to where the bleeding is and plug up the hole. This is the first step in the clotting process. When the platelets plug the hole, they release chemicals that attract more sticky platelets and also activate various proteins in the blood known as

57. Îáùåñòâî áîëüíûõ ãåìîôèëèåé/Association For Persons Wit Top/World/Russian/Здоровье/Заболевания/Гемофилия http://www.blood.ru/hemophilia/

58. Welcome To HFA The hemophilia Federation of America is a national nonprofit organization HFA provides HAWC (hemophilia Adult Weekend Camp) information and registration http://www.hemophiliafed.org/

/*********************************************** * AnyLink CSS Menu script- © Dynamic Drive DHTML code library (www.dynamicdrive.com) * This notice MUST stay intact for legal use * Visit Dynamic Drive at http://www.dynamicdrive.com/ for full source code ***********************************************/ Home FAQ Annual Report Patient Notification ... Contact Us URGENT MESSAGE TO ALL! In times of crisis, "Family comes first"! The Hemophilia Federation of America announces the creation of the Hemophilia Disaster Relief Fund to assist families with blood clotting disorders that have been affected by natural disasters. To donate to this fund, click below: DONATE TO THE HFA DISASTER RELIEF FUND Thanks to our donors (opens in a new window) OUR MISSION T he Hemophilia Federation of America is a national nonprofit organization that assists and advocates for the blood clotting disorders community. OUR VISION T he vision of the Hemophilia Federation of America is that the blood clotting disorders community has removed all barriers to both choice of treatment and quality of life. SYMPOSIUM 2006 Our 2006 Annual Meeting and Symposium will be held March 30 through April 2, 2006 in St. Louis, Missouri. Click the link below for more information.

59. Medical And Hemophilia References Personal page from Rick and Linda Thomas. http://www.geocities.com/HotSprings/3160/medpage.html

Medical And Hemophilia References Hope these references are useful if you know any more links that fit in please e-mail me Hot Links Gold Coast Division of the Florida Chapter COTT Hemophilia Page World Federation Of Hemophilia> ... Florida Chapter of the NHF This page created by Rick and Linda Thomas click to return to our Home Page If you have comments or suggestions, email me at rthomas@gate.net

60. EMedicine - Hemophilia, Type B : Article By Brendan R Furlong, MD hemophilia, Type B hemophilia B is an inherited, X-linked, recessive disorder resulting in deficiency of functional plasma coagulation factor IX. http://www.emedicine.com/emerg/topic240.htm

(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Patient Education Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Emergency Medicine Hematology And Oncology Hemophilia, Type B Last Updated: June 23, 2004 Rate this Article Email to a Colleague AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography Author: Brendan R Furlong, MD , Clinical Chief, Department of Emergency Medicine, Georgetown University Hospital Coauthor(s): Mary A Furlong, MD , Assistant Professor, Department of Pathology, Georgetown University School of Medicine Brendan R Furlong, MD, is a member of the following medical societies: American College of Emergency Physicians Editor(s): William Gossman, MD , Assistant Professor, Department of Emergency Medicine, Rosalind Franklin University of Medicine and Science, Project Medical Director, Department of Emergency Medicine, Mount Sinai Hospital; Francisco Talavera, PharmD, PhD

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