81. GeneTests: Search Results Chapman Institute/Center for Genetic testing at St Francis. Genetics Laboratory.Tulsa, OK (dna) Diagnostic Laboratory. Baltimore, MD. Garry R Cutting, MD http://www.genetests.org/query?testid=15665

82. An Introduction To Genetics And Genetic Testing They look toward a future where genetic test results are an important part of every Genes are found in specific segments along the length of human (dna), http://kidshealth.org/parent/system/medical/genetics.html

KidsHealth Parents What do you know about your family tree? Have any of your relatives had health problems that tend to run in families? Which of these problems affected your parents or grandparents? Which ones affect you or your brothers or sisters now? Which problems might you pass on to your children? Thanks to advances in genetics, doctors now have the tools to understand how certain illnesses, or increased risks for certain illnesses, pass from generation to generation. According to some health experts, the definition of an inherited or genetic illness should be expanded beyond the classic inherited disorders (like hemophilia and sickle cell anemia ) to include many types of cancer , Alzheimer's disease, and other illnesses. They look toward a future where genetic test results are an important part of every healthy person's medical file. Genes and Chromosomes Each person has a unique set of chemical blueprints that determines how his or her body looks and functions. These blueprints are contained in a complex chemical called deoxy-ribonucleic acid (DNA), a long, spiral-shaped molecule that's found inside each body cell. DNA carries the codes for genetic information and is made of linked subunits called nucleotides. Each nucleotide contains a phosphate molecule, a sugar molecule (deoxyribose), and one of four coding molecules called bases (adenine, guanine, cytosine, or thymine). The sequence of these four bases determines the genetic code.

83. Resource Center > Predictive DNA Testing Predictive (dna) testing for Heritable Cancers Promises and Pitfalls As moregenes are identified and different tests are developed, the need to address http://cancerresources.mednet.ucla.edu/5_info/5c_archive_lec/1998/dna.htm

Home Information Resource Archives - Lecture Summaries Click here for a print-friendly version Predictive DNA Testing for Heritable Cancers: Promises and Pitfalls Wayne W. Grody, M.D., Ph.D., UCLA medical geneticist, DNA diagnostic laboratory director and professor Winter 1998 If scientists are able to clone sheep, determine something called a "DNA fingerprint", and even discover a breast cancer gene, why don't they know enough to be able to stop or prevent cancer? This question is common, and it speaks to both the promises that genetic discoveries hold, and the general lack of understanding that most people have about the complexities of genetic (heritable) disease. Background At the same time, the growing power to understand and manipulate genes has released critical and hotly debated ethical issues. The National Center for Genome Research has set aside 5% of its budget to study the inherent ethical issues. The Ethical Legal and Social Implications program (ELSI) has begun to tackle some of the ethical issues that emerge from gene testing to gene interventions.

84. New DNA Test Approved For Cystic Fibrosis Carrier Screening And Diagnosis Other tests are available that analyze the entire gene, looking for all the Tm Bioscience receives FDA clearance for cystic fibrosis (dna) test (press http://www.labtestsonline.org/news/cf050624.html

TESTS Test not listed? A/G Ratio ACE ACT ACTH AFB Culture AFP Maternal AFP Tumor Marker Albumin Aldolase Aldosterone Allergies ALP Alpha-1 Antitrypsin ALT Ammonia Amylase ANA Antibody Tests Antiglobulin, Direct Antiglobulin, Indirect Antiphospholipids Antithrombin Apo A Apo B ApoE Genotyping aPTT AST Autoantibodies Bicarbonate Bilirubin Blood Culture Blood Gases Blood Smear BMP BNP Bone Markers BRCA BUN C-peptide CA-125 CA 15-3 CA 19-9 Calcitonin Calcium Cardiac Biomarkers Cardiac Risk Cardiolipin Antibodies Catecholamines CBC CCP C. diff CEA Celiac Disease Tests CF Gene Mutation Chemistry Panels Chlamydia Chloride Cholesterol CK CK-MB CMP CMV Coagulation Factors Complement Levels Cortisol Creatinine Creatinine Clearance CRP CRP, high-sensitivity

85. PKD - Gene Test Now that a gene test is available for polycystic kidney disease (PKD), FAB intendsto set up Cats tested negative using the (dna) test can only be added, http://www.fabcats.org/pkd_gene_test.html

Feline Advisory Bureau About FAB Membership Make a donation Boarding Catteries ... PKD scheme gene test for pkd fab pkd negative register Breeders of Persians and Exotics will be delighted to hear that at last a genetic test for PKD is available. The gene that causes autosomal dominant PKD in Persian cats has been identified and gene tests have now been developed for the disease. A test is available in the UK through the Langford Veterinary Diagnostic Laboratory at Bristol University Veterinary School , or samples can be sent to the Veterinary Genetics Laboratory VGL) in California , USA . Samples have been validated between the centres using blood from cats screened under the FAB PKD Screening Scheme PKD is an inherited kidney disease which has become very common in Persian cats and Exotic Shorthairs. Many cat breeders are aware of the problem and have been taking steps to eradicate the gene defect from their breeding lines. Up until recently the only practical way to identify the affected cats has been by ultrasound scanning of the kidneys, and the Feline Advisory Bureau established a UK PKD Ultrasound Screening Scheme for the disease in 2000. Almost 2300 cats have been scanned in this time with an average positive result of 33 per cent. Now that a gene test is available this will most likely become the test of choice for many breeders because the sample can be taken by a local vet and kittens do not have to be 10 months old before a reliable result can be obtained. However, ultrasound scanning remains a good screening test for the disease and FAB PKD Ultrasound Screening will continue to be available to breeders who prefer to use this method.

86. CSIRO - New Multi-gene DNA Test For Beef Marbling Australian cattle farmers are now better equipped to produce the perfect steakevery time with the identification and commercialisation of a new gene marker http://www.csiro.au/index.asp?type=mediaRelease&id=beefmarble&stylesheet=mediaRe

87. Stanford Cancer Center - DNA Testing For Cancer Genetic Susceptibility Genes (dna) testing For Cancer Susceptibility Genes. There are a growing number of genesbeing discovered that predispose a person to developing cancer for which http://cancer.stanfordhospital.com/healthInfo/cancerDiagnosis/geneticTesting/dna

Home For Patients For Health Professionals Students ... Before Undergoing Genetic Testing DNA Testing For Cancer Susceptibility Genes There are a growing number of genes being discovered that predispose a person to developing cancer for which testing is available. Due to the complexity of the testing and the issues surrounding testing, in 1996 the American Society of Clinical Oncology (ASCO) published guidelines on when to offer cancer predisposition testing to patients. ASCO recommended that cancer predisposition testing be offered only when: there is a strong family history of cancer or very early age of onset of cancer the genetic test can be clearly interpreted the results of the test will influence the medical management of the patient with cancer or their family members ASCO grouped hereditary cancers/cancer genetic testing into three categories: Group 1 Families with a well-defined inherited cancer syndrome where the genetic test result will affect medical care. Genetic testing is considered part of the standard management of these families. Syndromes include: Familial Adenomatous Polyposis (FAP) Multiple Endocrine Neoplasia (MEN) 2A, 2B

88. Restriction Fragment Length Polymorphisms (RFLPs) screening human (dna) for the presence of potentially deleterious genes ( Case 1 ); By testing the (dna) of prospective parents, their genotype can be http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/RFLPs.html

Index to this page Screening for the sickle-cell gene Screening for a RFLP "marker" DNA "fingerprinting" Short Tandem Repeats (STRs) Restriction Fragment Length Polymorphisms (RFLPs) Restriction enzymes cut DNA at precise points producing a collection of DNA fragments of precisely defined length. These can be separated by electrophoresis , with the smaller fragments migrating farther than the larger fragments. complementary to a run of nucleotides in one or more of the restriction fragments and is radioactive (or fluorescent). If probes encounter a complementary sequence of nucleotides in a test sample of DNA, they bind to it by Watson-Crick base pairing and thus identify it. Polymorphisms are inherited differences found among the individuals in a population. RFLPs have provided valuable information in many areas of biology, including: screening human DNA for the presence of potentially deleterious genes ("Case 1"); providing evidence to establish the innocence of, or a probability of the guilt of, a crime suspect by DNA "fingerprinting" ( "Case 3" Case 1 : Screening for the sickle-cell gene Sickle cell disease is a genetic disorder in which both genes in the patient encode the amino acid valine (Val) in the sixth position of the beta chain (beta S ) of the hemoglobin molecule. "Normal" beta chains (beta

89. Smart State Catalyst Issue10 Late in 2002, genetic Solutions released the world s first (dna) test for beef The original single gene test was capable of halving the odds of consumers http://www.smartstate.qld.gov.au/resources/publications/catalyst/2004/issue_10/o

Access keys Skip to content Skip to footer Problems viewing this site ... Contact us Search: News Events Publications Success stories ... Consultation process Catalyst - Issue 10 Message from the Premier Raising the steaks with DNA testing Queensland invention Obesity controlled pills ... Publications Raising the steaks with DNA testing Foodies looking for the tenderest steaks will find their quest much easier soon, thanks to world leading-edge DNA tests being marketed for the first time by Brisbane's Genetic Solutions. Genetic Solutions was formed in 1998 by Dr Jay Hetzel and Dr Gerard Davis, two scientists formerly employed by the Commonwealth Scientific, Industrial and Research Organisation (CSIRO). Late in 2002, Genetic Solutions released the world's first DNA test for beef tenderness. Then in November last year, a second improved test was released, a two-gene test for tenderness. Genetic Solutions is now on the verge of commercially releasing a new package that has four tests, two for tenderness and two for marbling. "It's the only package in the world that has four tests," Dr Hetzel said. "The only other similar products I know of come from two American companies, and they're each based on only a single gene."

90. Breast And Ovarian Cancer: Genetic Testing When The Mutation In The Family Is Un In this test, scientists sequence both of the genes known to cause A (dna) testcan also miss a mutation, or find a mutation that is not actually present. http://www.genetichealth.com/BROV_Genetic_Testing_When_the_Mutation_in_the_Famil

Home Learn Breast and Ovarian Cancer Genetic Testing When the Mutation in the Family is Unknown Conditions Alzheimer's Breast Cancer Colon Cancer Diabetes ... Ovarian Cancer Tools Medical Glossary Genetics 101 Overview of Genetics Inheritance Patterns DNA Mutations Changing Your Risk ... Inherited/Sporadic Cancer Genetic Testing The Testing Process Where Is Testing Done? Who Orders Genetic Tests? Costs of Genetic Testing Ethical Issues Genetic Information Genetic Discrimination Health Insurance Research Participation Types of Clinical Trials What Should I Know? From Gene To Cure List of Clinical Trials Resources Genetic Counseling Find a Genetic Counselor Find a Support Group Getting Medical Records ... Help for Birth Parents Awards "G enetic Health does more than hit just a home run — it's a grand slam in the bottom of the ninth to win the game ... one of the very best health-related sites we have ever had the pleasure to view." — Wally Gross, Surfers Choice Review Team

91. Gene Tests For Heart Disease: Perils And Promise gene tests for heart disease perils and promise Advances in genetics meanthat (dna) tests for common complex conditions such as heart disease will soon http://www.londonideas.org/internet/school/GenetestsforheartdiseasePerilsandprom

Gene tests for heart disease: perils and promise The Royal Society Summer Science Exhibition July 4-7 2005 Advances in genetics mean that DNA tests for common complex conditions such as heart disease will soon be possible. This raises three issues : How can we identify the genes involved? Genetics influences heart disease by: Mutations of large impact on an individual’s risk that are MONOGENIC (mutation in one gene has impact), but are RARE Mutations of small impact on an individual’s risk that are POLYGENIC (mutations in more than one gene necessary for impact) and are COMMON Both effects are modified by ENVIRONMENT (eg diet, smoking) Will DNA based tests be useful for doctors? Will they: Have predictive power over-and-above established risk factors? Take environmental interactions into account? Be based on estimate of risk that is accurate and reproducible? Will they be psychologically damaging? It is important to understand: Why people want a test How they perceive they can control a condition diagnosed by a DNA test How we can avoid the pitfalls of false reassurance and fatalism.

92. Log In Problems In a particular family, a gene test may or may not give useful results. genetic tests are available for a few genes that influence breast cancer. http://www.medscape.com/pages/sites/dnas/pathandout/breastcancer

Unable to Deliver Requested Page In order to use Medscape, your browser must be set to accept cookies delivered by the Medscape site. To find out how to adjust your browser settings to accept cookies, please click here Medscape uses cookies to customize the site based on the information we collect at registration. The cookies contain no personally identifiable information and have no effect once you leave the Medscape site. You can read more about our use of cookies in our About Medscape Help WebMD Health

93. Genetics Information - Office Of Rare Diseases Information about the genetics of cancer; gene testing; Information aboutDNA sequences to explore questions about processes of living systems to http://ord.aspensys.com/asp/resources/gen_info.asp

SEARCH Genetics Information Resources on genetic information, genetic research, genetic testing laboratories and clinics, and genetic counseling services. When you enter the Web sites listed below, you will leave the ORD Web site. Please return to our Web site to find more information on rare diseases, patient support groups, and genetic laboratories and clinics. Genetic and Rare Diseases Information Center Established by the National Human Genome Research Institute (NHGRI) and the Office of Rare Diseases (ORD), the Genetic and Rare Diseases Information Center employs experienced information specialists to answer in English or Spanish questions from the general public, including patients and their families, healthcare professionals, and biomedical researchers. Genetic and Newborn Screening Resource Center of the United States (GeNeS-R-US) GeNeS-R-US is a cooperative agreement between the Maternal and Child Health Bureau (MCHB), Genetic Services Branch, and the University of Texas Health Science Center at San Antonio (UTHSCSA) Department of Pediatrics. GeNeS-R-US provides information and resources in the area of newborn screening and genetics to benefit health professionals, the public health community, consumers, and government officials. Gene Tests Information about medical genetics, genetic testing, and diagnostic clinics and laboratories for healthcare providers, researchers, and the public.

94. BBC NEWS | In Depth | Leicester 2002 | Bringing The Genetic Lab To You Current genetic tests rely on extracting (dna) from blood. The sample has to besent away to a It can test for a number of gene mutations and pathogens http://news.bbc.co.uk/1/hi/in_depth/sci_tech/2002/leicester_2002/2255846.stm

CATEGORIES TV RADIO COMMUNICATE ... INDEX SEARCH You are in: In Depth: Leicester 2002 News Front Page World ... Programmes SERVICES Daily E-mail News Ticker Mobile/PDAs Text Only ... Help EDITIONS Change to World Friday, 13 September, 2002, 14:00 GMT 15:00 UK Bringing the genetic lab to you Genetic test results could be available in minutes By Helen Briggs BBC News Online science reporter in Leicester Going to a high street chemist for an instant genetic test could become a reality in the next year. Scientists are developing a cheaper, quicker genetic testing system that gives results in half an hour. It's not DIY genetics Dr Paul Debenham A person would be able to find out about their health and genetic profile, by simply providing a saliva sample. It should be able to diagnose the strain of microbe responsible for an infection or find out whether someone is likely to have an adverse reaction to a prescribed medication. In the future, the kit might even be able to tell whether someone has a gene that predisposes them to breast cancer or whether they are genetically susceptible to getting a deep vein thrombosis (DVT) on long flights. On-the-spot diagnosis Current genetic tests rely on extracting DNA from blood. The sample has to be sent away to a lab and the results take days.

95. DNA 101 This page addresses (dna) only as it applies to YChromosome testing and genealogy . Chromosome One of the threadlike packages of genes and other (dna) in http://blairgenealogy.com/dna/dna101.html

BLAIR DNA Project DNA 101: Y-Chromosome Testing DNA 101 is an attempt to take the extremely complex and confusing subject of Genetics and DNA and simplify it into layman terms. This page addresses DNA only as it applies to Y-Chromosome testing and genealogy. Technical terms are defined in this same context. This page is broken down into the following sections: DNA Chromosomes The Y-Chromosome Test the Y-Chromosome ... Links DNA Deoxyribonucleic acid (DNA) is the chemical inside the nucleus of all cells that carries the genetic instructions for making living organisms. A DNA molecule consists of two strands that wrap around each other to resemble a twisted ladder. The sides are made of sugar and phosphate molecules. The “rungs” are made of nitrogen-containing chemicals called bases . Each strand is composed of one sugar molecule, one phosphate molecule, and a base . Four different bases are present in DNA - adenine (A), thymine (T), cytosine (C), and guanine (G). The particular order of the bases arranged along the sugar - phosphate backbone is called the DNA sequence; the sequence specifies the exact genetic instructions required to create a particular organism with its own unique traits. Each strand of the DNA molecule is held together at its base by a weak bond. The four

96. News@nature the genetics company (dna) Direct in San Francisco offers home tests for genes Genetic testing, (dna) Direct says, can help you to take charge of your http://www.nature.com/news/2005/050314/full/050314-16.html

@import "/news/style.css"; nature.com homepage Jump to main content Jump to navigation ... Browse by subject Search This site All of nature.com Advanced search Home News Features ... Stories by subject NEWS CHANNELS My news Biotechnology Careers Drug discovery ... For librarians Test your own DNA This article is available to Premium and Premium plus subscribers. With a Premium subscription you get full access to news@nature.com for the previous 30 days, and the ability to personalise your own news page. With a Premium plus subscription you get full access to news@nature.com , the full archive back to 1998, the ability to personalise your own news page, and articles up to 2 weeks before they appear in print. Existing personal subscribers to Nature Nature Medicine Nature Biotechnology or Nature Reviews Drug Discovery now receive news@nature.com Premium Plus access free with their subscription. Simply login with your existing username and password. If you do NOT currently subscribe to one of these journals, check a journal below and you will be redirected to the appropriate subscription page. Get information on institutional site license access here Current subscribers Log in to view the article USERNAME PASSWORD Save password Forgotten password?

97. HON - News : New DNA Test Catches Colon Cancer FRIDAY, April 16 (HealthDayNews) A new test that identifies (dna) changes earlier fecal (dna) tests for colorectal cancer have looked at gene mutations. http://www.hon.ch/News/HSN/518433.html

What is it? Speech: On / Off HONcode sites All Web sites HONselect News ... X Y Z Browse archive: S A J J ... J Posting date: 16-APR-2004 Other news for: Colonic Neoplasms Genetics Resources from HONselect New DNA Test Catches Colon Cancer Genetic marker may help identify malignancies without need for colonoscopy By Steven Reinberg HealthDay Reporter FRIDAY, April 16 (HealthDayNews) A new test that identifies DNA changes in your stool could lead to a noninvasive way of screening for colon cancer, a study finds. An Austrian research team found that by testing stool samples for changes in DNA methylation, which is a form of genetic alteration common in colorectal cancer cells, they were able to identify colorectal cancer about 90 percent of the time. "There are certain type of changes in DNA that are specific to certain tumors," said lead researcher Dr. Martin Widschwendter, a professor of obstetrics and gynecology from the Medical University of Innsbruck. One of these is called DNA methylation, he explained. According to Widschwendter, earlier fecal DNA tests for colorectal cancer have looked at gene mutations. However, these tests are not nearly as accurate as this new one. Widschwendter's team looked for the most promising DNA methylation markers from a long list of candidate genes by looking for DNA changes in stools of cancer patients and healthy controls.

98. CBS News | Breaking The Code | March 5, 2003 09:11:19 Donna Upchurch tested her baby Allison with a doit-yourself gene test. One company, (dna) Print Genomics offers an at home (dna) test kit that will tell http://www.cbsnews.com/stories/2003/03/04/sunday/main542739.shtml

SEARCH: CBSNews.com The Web document.write('') Home U.S. World Politics ... CBS News Video March 5, 2003 09:11:19 The Early Show CBS Evening News 48 Hours 60 Minutes ... Section Front E-mail This Story Printable Version Breaking The Code March 1, 2003 (Photo: CBS/AP) (CBS) It may look like Marty Schiff was brushing his teeth in the privacy of his Pittsburgh kitchen, but he was testing his DNA. "When I opened it, there were two swabs in it with instructions," says Schiff. Instructions from a DNA test kit he ordered by mail. "They have you roll the swabs along your inside cheek for 20 times each and let them air dry," says Schiff. He was testing for a genetic disorder called Hemochromatosis, which can cause the body to store lethal amounts of iron. The company that makes these kits, Healthcheck USA, will report the results to him, not to his doctor and not to his insurance company. I like the fact that I can do it at home. I'm in control. I don't have to get a doctor's permission to get the genetic test," says Schiff. "You do it and you send it back. And you'll get your results mailed directly to you after that." Donna Upchurch tested her baby Allison with a do-it-yourself gene test. When Allison was born, Donna was offered a newborn screening kit and on a whim, did the test and mailed it in.

99. ARS Project: Improvement Of DNA Delivery For Gene Transfer In Economically Impor Research Project IMPROVEMENT OF (dna) DELIVERY FOR gene TRANSFER IN Germlinetransformation of the honeybee will then be tested using vector and helper http://www.ars.usda.gov/research/projects/projects.htm?accn_no=404684

100. ARS Project: Improvement Of DNA Delivery For Gene Transfer In Economically Impor Research Project Improvement of (dna) Delivery for gene Transfer in Germlinetransformation of the honeybee will then be tested using vector and helper http://www.ars.usda.gov/research/projects/projects.htm?ACCN_NO=404684

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