101. CNN.com - Ebola Outbreak 'not Contained' - Feb. 19, 2003 UN health officials confirmed on Wednesday that a disease outbreak killing scores of people in the Republic of Congo was ebola and warned that the highly http://www.cnn.com/2003/WORLD/africa/02/19/congo.ebola.ap/

The Web CNN.com Home Page World U.S. Weather ... Special Reports SERVICES Video E-mail Newsletters CNNtoGO SEARCH Web CNN.com Ebola outbreak 'not contained' Ebola is spread through bodily fluids and has a two to 21-day incubation period. Story Tools BRAZZAVILLE, Republic of Congo (AP) U.N. health officials confirmed on Wednesday that a disease outbreak killing scores of people in the Republic of Congo was Ebola and warned that the highly lethal haemorrhagic fever could still be spreading. "We're not suggesting that this is over or even contained. We're treating it as an active outbreak," Iain Simpson, a World Health Organization (WHO) spokesman in Geneva, said. So far, 73 people have been infected, of whom 59 have died, according to WHO investigators. Government health officials in the tiny Central African nation report 80 cases with 67 deaths. The Cuvette West region, where the deaths have occurred, has been quarantined by the government since last week. Blood samples drawn from victims in the region tested positive for the Ebola virus, Josef Mboussa, a top official in Republic of Congo's health ministry, said. The disease is one of the world's deadliest, causing rapid death through massive blood loss in up to 90 percent of those infected.

102. WHO Declares Uganda Free Of Ebola Virus CNN http://cnn.com/2001/WORLD/africa/02/28/uganda.ebola.ap/index.html

103. CNN - Deadly Ebola Virus Lurks In The Shadows - Oct. 18, 1995 In 1976, ebola climbed out of its primordial hiding place in the jungles of Africa, ebola virus victims usually crash and bleed, a military term which http://www.cnn.com/HEALTH/9510/emerging_diseases/

Fear among us Deadly Ebola virus lurks in the shadows October 18, 1995 Web posted at: 12:30 a.m. From Correspondent Jim Clancy LONDON (CNN) Fear gripped their faces; uncertainty tortured their minds. The people of Zaire waited outside clinics, churches and in their own homes for treatment for a new horrible disease. But there was no cure. They watched people die, hoping that they would be spared the same violent death. In 1976, Ebola climbed out of its primordial hiding place in the jungles of Africa, and in two outbreaks in Zaire and Sudan it wiped out 600 people. To this day, even the most basic questions about the disease remain a mystery. Ebola virus victims usually "crash and bleed," a military term which literally means the virus attacks every organ of the body and transforms every part of the body into a digested slime of virus particles. "Ebola does in ten days what it takes HIV ten years to accomplish," wrote Richard Preston in his best-selling non-fiction book "The Hot Zone." Dr. Lindsey Martinez of the World Health Organization said that no one knows where Ebola hides in between epidemics. "And the investigations are still going on, looking at the animal reservoir to try and find which animal or insect may be harboring the virus and allowing it to re-emerge from time to time as happened in Zaire," Martinez said.

104. Fast, One-shot Ebola Vaccine Developed CNN http://cnn.com/2003/HEALTH/08/06/ebola.vaccine.ap/index.html

105. Ebola Zaire ebola Zaire. (In all her glory). ebola is a virus named after a river in Zaire, its first site of discovery. A usually fatal filovirus which affects monkeys http://cydathria.com/ebola.html

Ebola Zaire (In all her glory) Ebola is a virus named after a river in Zaire, its first site of discovery. A usually fatal filovirus which affects monkeys, apes and humans, it is a cause of viral hemorrhagic fever there are others. Filoviruses are string-shaped, often with a little hook or loop at one end. Another, somewhat less deadly filovirus is the Marburg virus. Ebola is classified as a Level 4 pathogen (higher than AIDS) with a 2 to 21 day (7 to 14 days average) incubation period. There are currently four known strains of Ebola: Zaire, Sudan, Reston and Tai. All cause illness in sub-human primates. Only Ebola Reston does not cause illness in humans. The mortality rate of Ebola victims is between 60% and 90%; with Ebola Sudan at 60% and Ebola Zaire at 90%. Ebola destroys the brain more thoroughly than does Marburg, and Ebola victims often go into epileptic convulsions during the final stage. The convulsions are generalized grand mal seizures the whole body twitches and shakes, the arms and legs thrash around, and the eyes, sometimes bloody, roll up into the head. The tremors and convulsions of the patient may smear or splatter blood around. Possibly this epileptic splashing of blood is one of Ebola's strategies for success it makes the victim go into a flurry of seizures as he dies, spreading blood all over the place, thus giving the virus a chance to jump to a new host a kind of transmission through smearing. Ebola (and Marburg) multiplies so rapidly and powerfully that the body's infected cells become crystal-like blocks of packed virus particles. These crystal are broods of virus getting ready to hatch from the cell. They are known as bricks. The bricks, or crystals, first appear near the center of the cell and then migrate towards the surface. As a crystal reaches a cell wall, it disintegrates into hundres of individual virus particles, and the broodlings push through the cell wall like hair and float away in the bloodstream of the host. The hatched Ebola particles cling to cells everywhere in the body, and get inside them, and continue to multiply. It keeps on multiplying until areas of tissue all through the body are filled with crystalloids, which hatch, and more Ebola particles drift into the bloodstream, and the amplification continues inexorably until a droplet of the hosts blood can contain a hundred million individual particles.

106. Ebola Fact Sheet Fact Sheet from the World Health Organization about ebola Haemorrhagic Fever http://www.who.int/inf-fs/en/fact103.html

107. Ebola ebola and Marburg Hemorrhagic Fevers (Note ebola and Marburg hemorrhagic Agent and Vector The agents for ebola and Marburg HFs are virions that are http://www3.baylor.edu/~Charles_Kemp/ebola.htm

Back to Infectious Diseases or Refugees Ebola and Marburg Hemorrhagic Fevers (Note: Ebola and Marburg hemorrhagic fevers (HFs) are discussed together because of similarities between them. Last update 11/2001. Primary Distribution : Ebola: The Congo, Sudan, Ivory Coast, Gabon, and most recently, Uganda in East, Central, and West Africa. Marburg: Uganda and Kenya in West Africa (Centers for Disease Control [CDC], 2000; World Health Organization [WHO], 2000). Agent and Vector : The agents for Ebola and Marburg HFs are virions that are members of the Filoviridae family, which is passed human to human through exposure to body fluids or by other means, including handling equipment touched by infected persons. The virus is also transmitted by handling infected animal (primate) tissue. The animal host is not known. Ebola and Marburg HFs are highly contagious, especially in later stages. The CDC has guidelines for management of patients with suspected viral hemorrhagic fever (Centers for Disease Control [CDC], 1996). Ebola and Marburg HFs are considered by the CDC to be Category A biological warfare (BW) agents (CDC, 2000). See bioterror box below. Incubation : 3-16 days.

108. CNN.com - Supplies Run Short As Ugandan Authorities Wrestle With Ebola - October CNN http://www.cnn.com/2000/WORLD/africa/10/17/uganda.ebola.02.ap/index.html

world africa Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Supplies run short as Ugandan authorities wrestle with Ebola GULU

109. Ebola ebola Hemorrhagic Fever Facts answers questions about the disease. ebola Outbreaks - information about outbreaks of ebola haemorrhagic fever reported to http://www.cannylink.com/diseaseebola.htm

Web www.CannyLink.com Search mode: Ebola Free At-Home DNA Testing Kit Death in 20 Days - dedicated to the education of the general public about the emergence, spread, and deadly effects of the Ebola Virus. Disease Information: Ebola Haemorrhagic Fever - information for travellers from Health Canada. Dr. Frederick A. Murphy Talks about the Ebola Virus - interview with one of the world authorities on viruses. Ebola Epidemic in Zaire Ebola Fan Club - informative site that takes a look at ebola through the eyes of a 16 year old boy from Ohio. Ebola Information - National Center for Infectious Diseases Ebola Information Headquarters - links to information about the ebola virus. Ebola Virus Outbreak - from the World Health Organization. Ebola Frequently Asked Questions - information about the four identified strains (Ebola Zaire, Ebola Sudan, Ebola Reston, and Ebola Tai). Ebola Haemorrhagic Fever - describes transmission, symptoms, treatment, and history of the disease since its identification after outbreaks in northern Zaire and southern Sudan in 1976. Ebola Hemorrhagic Fever Facts - answers questions about the disease.

110. Congo Health Minister Disease Outbreak Probably Not Ebola CNN http://cnn.com/2001/WORLD/africa/12/10/congo.outbreak.reut/index.html

111. TED Case Study: Ebola And Trade The ebola virus is a rare and extremely deadly virus which has appeared in ebola is one of the most gruesome and deadly viruses in its effects on its http://www.american.edu/TED/ebola.htm

TED Case Studies Ebola, Trade, and the Environment CASE NUMBER: CASE MNEMONIC: EBOLA CASE NAME: Ebola and Trade IDENTIFICATION LEGAL CLUSTERS GEOGRAPHIC CLUSTERS TRADE CLUSTERS ... OTHER FACTORS I. Identification 1. The Issue The Ebola virus is a rare and extremely deadly virus which has appeared in scattered places around the world, most often in Zaire. It is not known where this virus exists in nature, and Ebola is only obvious when had by humans and monkeys. The virus has affected our trade in monkeys and has also affected our trade in informationor lack of it, because the existence of the virus may be kept secret so it does not scare away tourism (another form of trade). The Ebola virus may also be traded for use in biochemical warfare, although there is no evidence of this. There is also no knowledge of where this virus naturally resides, but it can travel fairly easily. 2. Description The Ebola virus is named after the Ebola River in northern Zaire, which flows a short distance north of Yambuku, a small town where the first person in whom this virus was spotted lived. This case study will first describe Ebola's victims, the virus in particular, and responses to the virus. It will go on to describe the history of the virus, and its relationship to trade. This case study also presents related cases, the type of environmental problem, and the economic impact of Ebola, among other topics. Ebola's victims The Ebola virus causes a severe hemorrhagic fever. This fever occurs most often 7-14 days after infection (with the range of 2-21 days).

112. CNN.com - Officials Suspect New Ebola Case In South Uganda - November 3, 2000 CNN http://www.cnn.com/2000/WORLD/africa/11/03/health.uganda.ebola.reut/index.html

world africa Editions myCNN ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web WORLD TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Gates pledges $100 million for AIDS Davos protesters face tear gas ... MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters face tear gas MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Officials suspect new Ebola case in south Uganda KAMPALA, Uganda (Reuters) A second man is ill with suspected Ebola fever in southern Uganda after he helped to nurse a patient who died of the deadly haemorrhagic fever last week, health officials said on Friday.

113. The Big Picture Book Of Viruses - Filoviruses This image is a gag , but based on a real image of ebolaReston. ebov-r, ebola virus Reston, Electron micrograph of ebola Reston (Virginia) virus provided http://www.virology.net/Big_Virology/BVRNAfilo.html

The Big Picture Book of Viruses: Filoviridae Taxonomy: Description is on the taxonomic level of family. Taxon belongs to the order VO01. Mononegavirales. Taxon contains the following Genus 25.0.1. Filovirus. Host: Taxon infects vertebrates. Genome: Linear; single stranded; RNA. Genome monopartite. Genomic nucleic acid negative sense; not infectious. Total genome 19000 nucleotides long. Nucleotide sequences of 3'-terminus complementary to similar regions on the 5' end; conserved nucleotide sequences; the same in genera of same family. Morphology: Virions pleomorphic in shape; filamentous (either branched (sometimes extensively), or simple, circular, 6- or U-shaped,), or spheroidal (and uniform in size after purification by gradient centrifugation). Virions one type of particle only. Virions enveloped; greatly variable up to 1400 nm long, or 790-970 nm long (after purification); about 80 nm in diameter. Surface projections of envelope distinct; spikes (of 7 nm length); dispersed evenly over all the surface (at 10 nm intervals). Nucleocapsids filamentous (tubular); cross-banded; 50 nm in diameter. Symmetry helical. Pitch of helix 5 nm. Nucleocapsid has a dark central axis of 20 nm that appears to be the ribonucleic protein (RNP). The axial channel is about 10-15 nm in diameter. (Note: for more information about the taxonomy and structure of this virus, see the ICTV database below.)

114. CNN.com - Health - Relatives, Neighbors Shunning Ugandan Ebola Survivors - Novem CNN http://www.cnn.com/2000/HEALTH/11/10/uganda.ebola.ap/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Relatives, neighbors shunning Ugandan Ebola survivors A patient who recovered from the deadly Ebola virus holds his hospital discharge papers KAMPALA, Uganda

115. THINKQST\Web\epidemics\ebola The ebola Virus Hemorrhagic Fever first broke out in Zaire in 1976. ebola is a member of the RNA group of viruses, also known as filoviruses. http://library.thinkquest.org/11170/epidemics/ebola.html

The Ebola Virus Hemorrhagic Fever first broke out in Zaire in 1976. Ebola is a member of the [ RNA ] group of viruses, also known as [ filoviruses ]. Most filoviruses are carried in (or hosted by) rodents and small insects called [ arthropods ]. Unfortunately, the natural host(s) for Ebola are unknown. There are two types of Ebola: The Ebola virus of Zaire, which is a threat to humans, and the Ebola Reston, which does not affect humans. The Reston strain, found in Reston, VA, was found to affect only monkeys. However, officials believe Reston could mutate to affect humans. The symptoms of Ebola are very severe. With a 50 - 80% fatality rate, victims' futures are bleak. The symptoms occur in 3 steps: Fever, chills, aching muscles, headaches, and loss of appetite. Vomiting, diarrhea, chest pains, sore throat, and abdominal pain. Blood fails to clot and internal and external bleeding can occur.

116. Ebola's Return Leaves Villagers And Researchers Struggling For Answers CNN http://cnn.com/2002/WORLD/africa/01/07/ebola.return.ap/index.html

117. Ebola Fever Information ebola Reston virus in tissue cullture by coutesy of Dr.Miranda(Research Instiute for February 09, 2001 / 50(05);737 Outbreak of ebola Hemorrhagic Fever http://niah.naro.affrc.go.jp/disease/ebola/ebola.html

Welcome to the National Institute of Animal Health(Japan) WWW Home Page! Japanese version, here (Last updated www@niah.affrc.go.jp (WWW Administrator) Urgent informationEbola Fever Ebola Reston virus in tissue cullture by coutesy of Dr.Miranda(Research Instiute for Tropical Medicine, Philippines), Drs Sanchez and Humphrey(Centers for Disease Cotrol and Prevenntion, Atlanta) This listing will be updated when new information is made available. And some site does not open fulltime. WWW Site ProMED-Mail ] (Last updated February 09, 2001 / 50(05);73-7 Outbreak of Ebola Hemorrhagic Fever -Uganda, August 2000January 2001 -MMWR, CDC Ebola Disease information (CDC) Outbreak news index Haemorrhagic Fevers (WHO) Insitute for Molecular Virology Ebola Recommended Reading List ... Ebola Zaire Fan Club BIBLIOGRAPHY: Ebola Bibligraphy NIAH WWW Home Page

118. 'Ebola Spell' Teachers Stoned CNN http://cnn.com/2003/WORLD/africa/02/21/health.congo.ebola.reut/index.html

119. Ebola Suspected In Equatorial Guinea - (United Press International) The Minister of Health in Equatorial Guinea has issued an alert about the deadly ebola virus after a man with symptoms of the disease died last week. http://www.washingtontimes.com/upi-breaking/20050427-093159-2340r.htm

April 27, 2005 Washington D.C. Advertise Subscribe Site Map Front Page ... TWT Insider Stock Quotes Symbol Lookup Classifieds Home Guide Auto Weekend ... Arbor Ballroom Ebola suspected in Equatorial Guinea Bata, Equatorial Guinea, Apr. 27 (UPI) The Minister of Health in Equatorial Guinea has issued an alert about the deadly Ebola virus after a man with symptoms of the disease died last week. The Web site Afriquecentrale.info reported the alert was read on national radio. The minister advised any patient with symptoms of Ebola hemorrhagic fever, including a high fever and bleeding from the mouth, ears, nose or eyes, should be treated at a health facility. Ebola is one of the most deadly viral diseases known, killing 50 percent to 90 percent of those who become infected. It generally is spread by contact with bodily fluids of infected individuals, but the handling of infected chimpanzees also can transmit it. The alert recommended dead individuals who had Ebola symptoms should be buried to prevent the virus from spreading. Neighboring country Gabon has had Ebola outbreaks several times in recent years.

120. CNN.com - Health - Early Ebola Tests On Patient In Canada Negative - February 7, CNN http://cnn.com/2001/HEALTH/02/07/ebola.canada.02/index.html

MAIN PAGE WORLD U.S. WEATHER ... ABOUT US CNN TV what's on show transcripts CNN Headline News CNN International ... askCNN EDITIONS CNN.com Asia CNN.com Europe set your edition Languages Spanish Portuguese German Italian Danish Japanese Korean Arabic Time, Inc. Time.com People Fortune EW Early Ebola tests on patient in Canada negative WEB EXCLUSIVE Bill Delaney: Ebola scare in Canada HAMILTON, Ontario (CNN) Health officials in Canada said Wednesday preliminary tests on a woman feared to have the Ebola virus have been negative for the deadly hemorrhagic fever. However, they said viral isolation tests are still being conducted and they have not yet been able to rule out other viruses, such as Lassa or yellow fever, as the cause of her illness. "We're being extremely cautious," said Dr. Mark Loeb of Henderson Hospital, where the woman is being treated. But he emphasized the general public is not at risk. "We've had some results from the laboratory in Winnipeg, showing that the Ebola testing is negative," explained Loeb. "The real implication (is) that this greatly reduces the likelihood that this patient has been infected with the Ebola virus." VIDEO CNN's Elizabeth Cohen has more on the possible Ebola case in Canada Play video (QuickTime, Real or Windows Media)

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