81. BioMed Central | Abstract | Epidemiological Evidence Of Higher Susceptibility To The strikingly young age of new variant creutzfeldtjacob disease (vCJD) cases remains unexplained. Age dependent susceptibility to infection has been put http://www.biomedcentral.com/1471-2334/4/26/abstract

home journals A-Z subject areas advanced search ... Volume 4 Viewing options Abstract Full text PDF Associated material: Pre-publication history PubMed record Related literature: Articles citing this article on Google Scholar on ISI Web of Science Other articles by authors ... Similar articles (PubMed) Tools: E-mail to a friend Download references Post a comment Key E-mail Corresponding author Research article Epidemiological evidence of higher susceptibility to vCJD in the young Jean-Yves Cesbron and Alain-Jacques Valleron BMC Infectious Diseases Published Abstract Background The strikingly young age of new variant Creutzfeldt-Jacob disease (vCJD) cases remains unexplained. Age dependent susceptibility to infection has been put forward, but differential dietary exposure to contaminated food products in the UK population according to age and sex during the bovine spongiform encephalopathy (BSE) epidemic may provide a simpler explanation. Methods Using recently published estimates of dietary exposure in mathematical models of the epidemiology of the new variant Creutzfeldt Jacob disease (vCJD), we examine whether the age characteristics of vCJD cases may be reproduced. Results The susceptibility/exposure risk function has likely peaked in adolescents and was followed by a sharp decrease with age, evocative of the profile of exposure to bovine material consumption according to age. However, assuming that the risk of contamination was proportional to exposure, with no age dependent susceptibility, the model failed to reproduce the observed age characteristics of the vCJD cases: The predicted cumulated proportion of cases over 40 years was 48%, in strong disagreement with the observed 10%. Incorporating age dependent susceptibility led to a cumulated proportion of cases over 40 years old of 12%.

82. CWD Risk Considered Minimal creutzfeldtjacob disease occurs at the rate of one in 1 million. But telling people that their risk of dying in a car crash is astronomically higher again http://foodhaccp.com/msgboard.mv?parm_func=showmsg parm_msgnum=1005939

83. The Scientist :: Reopening The Debate On The Origins Of VCJD, Oct. 17, 2001 Already, senior officials at the UK s creutzfeldtjacob disease surveillance unit, based in Edinburgh, are penning a response to Venter s article (BMJ 2001, http://www.the-scientist.com/news/20011017/03

Please login or register DAILY E-MAIL RSS HANDHELD CURRENT ISSUE DAILY NEWS UPFRONT FEATURE ... ARCHIVES Oct. 17, 2001 Previous Archive Next DAILY NEWS Reopening the debate on the origins of vCJD A new epidemiological study suggests that variant Creutzfeldt-Jacob disease may have developed independently of animal spongiform encephalopathies. By Pat Hagan British Medical Journal will not be short of correspondence in the coming weeks. A paper And that, according to George Venters, the public health specialist at Lanarkshire Health Board who wrote the paper, is exactly what he intended. Venters, an epidemiologist with long experience of infectious diseases, is deeply troubled by what he calls 'speculation that has evolved into orthodoxy' on the causal link between the consumption of BSE-infected meat and variant CJD. Such is the sensitivity of his argument that it seems inconceivable it will not have the desired effect. Already, senior officials at the UK's Creutzfeldt-Jacob disease surveillance unit , based in Edinburgh, are penning a response to Venter's article ( BMJ The contents of the letter have not been revealed but it's almost inevitable that they will attempt to deconstruct his case and substantiate the available evidence that eating infected meat is the most probable cause of the disease in humans.

84. Creutzfeldt Jacob Disease - Watches Portal US A new search engine providing details on watches resources. http://watches.portal.us.com/creutzfeldt-jacob-disease.html

Sponsored Links Name Brand Watches On Sale Find all the hottest names in the watch industry. We will have the watch you are looking for. Creutzfeldt Jacob Disease Article: Creutzfeldt Jacob Disease information, pricing, and reviews MedlinePlus Medical Encyclopedia: Creutzfeldt-Jakob disease UK Creutzfeldt-Jakob Disease Surveillance Unit Summarizes the research in progress at the CJD unit and also provides background information about CJD and other human spongiform encephalopathies. Lancet 1996; 347: 921 25 Creutzfeldt-Jakob Disease Foundation, Inc. Information about CJD, interactive pages, profiles, polls and details of conferences. Creutzfeldt-Jacob Disease Health Canada - Variant Creutzfeldt-Jakob Disease (Variant CJD) One of Health Canada's mandates is to reduce the incidence of disease, conditions and personal injuries. CJD Voice.org - Awareness - Support - Latest News Find help, support, understanding and information concerning all variant forms of Creutzfeldt Jakob Disease, CJD. Creutzfeldt-Jakob disease Creutzfeldt-Jakob disease Creutzfeldt-Jakob disease (CJD) is a transmissible, rapidly progressing, fatal neurodegenerative disorder related to "mad cow disease."...(

85. PRION DISORDERS: ALZHEIMER'S DISEASE; PARKINSON'S DISEASE; CREUTZFELDT-JACOB'S D PRION DISORDERS ALZHEIMER S disease; PARKINSON S disease; creutzfeldtjacob S disease MOTOR NEURONE disease. I have to say I have no difficulty with the http://www.drmyhill.co.uk/article.cfm?id=360

86. MedlinePlus Medical Encyclopedia: Creutzfeldt-Jakob Disease CreutzfeldtJakob disease is a disorder involving rapid decrease of mental More recently, a type of disease called new variant Creutzfeldt-Jakob disease http://www.nlm.nih.gov/medlineplus/ency/article/000788.htm

@import url(/medlineplus/images/advanced.css); Skip navigation Medical Encyclopedia Other encyclopedia topics: A-Ag Ah-Ap Aq-Az B-Bk ... Z Creutzfeldt-Jakob disease Contents of this page: Illustrations Alternative names Definition Causes, incidence, and risk factors ... Prevention Illustrations Creutzfeldt-Jakob disease Central nervous system Alternative names Return to top Transmissible Spongiform Encephalopathy; Mad Cow - new variant CJD Definition Return to top Creutzfeldt-Jakob disease is a disorder involving rapid decrease of mental function and movement. These are abnormalities believed to be caused by damage done to the brain by a protein called a prion. This protein folds abnormally, and seems to encourage other proteins to become similarly misshapen, affecting their ability to function. Causes, incidence, and risk factors Return to top Creutzfeldt-Jakob disease can occur sporadically (for no known reason), as a result of exposure to contaminated products. Rarely, it can be genetically inherited. The disorder itself is rare, occurring in about 1 out of 1 million people. It usually first appears in midlife, beginning between ages 20 and 70, with average age at onset of symptoms in the late 50s. However, some cases have occurred in adolescents who have received

87. UK Creutzfeldt-Jakob Disease Surveillance Unit Summarizes the research in progress at the CJD unit and also provides background information about CJD and other human spongiform encephalopathies. http://www.cjd.ed.ac.uk/

The National Creutzfeldt-Jakob Disease Surveillance Unit The incidence of Creutzfeldt-Jakob disease (CJD) is monitored in the UK by the National CJD surveillance unit based at the Western General Hospital in Edinburgh, Scotland. The unit brings together a team of clinical neurologists, neuropathologists and scientists specialising in the investigation of this disease. This document is intended to summarise the research in progress at the CJD unit and also provide some background information about CJD and other human spongiform encephalopathies. We have also provided some links to other resources and contrary points of view available on the Web. Creutzfeldt-Jakob Disease Surveillance. Figures for the number of confirmed cases of the new variant of CJD and referrals of suspected cases of CJD to the surveillance unit over the last thirteen years. NCJDSU protocol for CJD surveillance across the UK. National Referral System . From July 2004, a new national reporting system was announced by the Chief Medical Officer . This is centred on the National CJD Reporting Form to be faxed, by the notifying clinician, to the National Creutzfeldt-Jakob Disease Surveillance Unit (NCJDSU), the National Prion Clinic (NPC) and the local CCDC.

88. Carerep Patients with new variant CreutzfeldtJakob disease and their families care and A study of patients with motor neurone disease focused on their http://www.cjd.ed.ac.uk/carerep.html

Patients with new variant Creutzfeldt-Jakob disease and their families: care and information needs Dr Margaret J Douglas Dr Harry Campbell Professor Robert G Will February 1999 Patients with new variant Creutzfeldt-Jakob disease and their families: care and information needs CONTENTS Executive Summary Acknowledgements Introduction Methods ... Results General pattern of care Initial management and investigations Palliative and terminal care After death Practical advice and help Emotional support Information Coordination and continuity of care Dealing with the media Why nvCJD is different Differences since nvCJD was announced Discussion Recommendations References Appendices Appendix 1: Interview guide for family interviews Appendix 2: Interview guide for professional interviews Appendix 3: Categories used to sort data Appendix 4: Glossary of abbreviations Executive Summary New variant Creutzfeldt-Jakob disease (nvCJD) is a new and devastating condition. The medical and social needs of patients with nvCJD, and of their relatives and carers, have not been clearly defined. This study sought to identify their needs for information and practical support, from the perceptions of the families and the professionals who had been involved in their care. In depth interviews were carried out with close family members of 19 patients with nvCJD. Semi-structured telephone interviews were carried out with selected health and social professionals involved in their care. These were supplemented by review of patients' case notes.

89. REGENT Antiseptics: Knowledge, Special Report: Creutzfeldt Jacob Disease REGENT Antiseptics knowledge Creutzfeldt Jacob disease, as an emerging disease has been the source of major concern within communities in Europe recently, http://www.regentantiseptics.com/regentweb/knowledge.nsf/page/5gpfn7

You are in: Home Special Reports > Special Report: Creutzfeldt Jacob Disease We are only able to answer queries specific to our antiseptic products and cannot provide general medical information on disease conditions or suggestions for medical treatment. Please contact your doctor for further information on these areas. Special Report: Creutzfeldt Jacob Disease By Kate Woodhead RGN DMS Creutzfeldt Jacob Disease, as an emerging disease has been the source of major concern within communities in Europe recently, where the incidence is highest. The disease is being actively researched in many corners of the world in order to understand how it affects patients and how it may be best managed by health professionals. Currently there are more questions than answers, although additional data is coming to light all the time. Ironically, the dynamic nature of the scientific information is also a problem for families of victims, hospitals and health care professionals. CJD is presenting a huge challenge to the scientific, epidemiological and health care professionals to identify and reduce possible transmissions of this new disease whose causative agent is even now, little understood ( 85% of all Creutzfeldt Jacob Disease is caused by sporadic CJD, the incidence worldwide is 1 in a million per year and it was first described in 1921(

90. REGENT Antiseptics: IPQ Test Creutzfeldt Jacob disease (CJD) These tests are designed to test your knowledge of various topics that are of critical importance in the field of Infection http://www.regentantiseptics.com/regentweb/ipq.nsf/quizform?openform&parentunid=

91. Creutzfeldt-Jakob Disease CreutzfeldtJakob disease is a disorder involving rapid decrease of mental function and movement. These are abnormalities believed to be caused by damage http://www.healthcentral.com/ency/408/000788.html

Dr. Dean TV Specials Newsletters Home ... Health Tools Search Choose a Health Topic * All Health Topics * Acne Addictions AIDS/HIV Alcohol Abuse Allergies Alternative Medicine Alzheimer's Arthritis Asthma Attention Deficit Disorder (ADHD) Backache Bipolar Affective Disorder Birth Control Blood Blood Pressure Bone/Joint/Tendon Bowel Brain Breast cancer Cancer Cerebral Palsy Cholesterol Cramps Crohn's Disease Cysts Dental/Oral Depression Diabetes Diet, Fitness, Looks Disabled/Special Needs Drug Abuse Ear/Nose/Throat Eating/Appetite Eczema Encephalitis Eye/Vision Fatigue Fever Flu Food Poisoning Foot Gallbladder Gastrointestinal Genetic/Congenital GERD/Heartburn Hair Loss Hair/Scalp Headache Hearing Heart Disease, Stroke Heat/Sunstroke Hepatitis Hernia Herpes High Blood Pressure Hormonal Immune Disorders Immunizations/Vaccines Impotence Incontinence/Bladder Infections Injuries Kidney/Urinary Kids Learning Disabilities Liver Lung Cancer Men Menopause, Postmenopause Migraine Mobility/Balance Multiple Sclerosis Muscle Neural Nosebleeds Pain Parasites Pituitary PMS Pregnancy Prostate Cancer Prostate Disorders Psoriasis Psychological Raynaud's Disease Respiratory Reye Syndrome Rheumatoid Arthritis Schizophrenia Seniors Sensory Sexually Transmitted Disease Skin Sleep Speech Disorders Spinal Thyroid Trauma Weight Loss Women Yeast Infections Home Health Encyclopedia Creutzfeldt-Jakob disease Creutzfeldt-Jakob disease Injury Disease Nutrition Poison ... Prevention Creutzfeldt-Jakob disease Definition: Creutzfeldt-Jakob disease is a disorder involving rapid decrease of mental function and movement. These are abnormalities believed to be caused by damage done to the brain by a

92. Health Canada - Variant Creutzfeldt-Jakob Disease (Variant CJD) One of Health Canada s mandates is to reduce the incidence of disease, conditions and personal injuries. http://www.hc-sc.gc.ca/english/diseases/cjd/bg4.html

93. Diagnosis Of Creutzfeldt - Jacob Disease. Prabhakar S, Bhatia R Neurol India Neurol India is an peerreviewed biomedical periodical of Neurological Society of India. http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2001;volume=49;iss

94. Official Mad Cow Disease Home Page The Internet s largest site for mad cow disease, BSE, scrapie, CJD, and other prion diseases. Coverage of news, prion molecular biology and research http://www.mad-cow.org/

7,651+ articles on mad cow and new variantCreutzfeldt-Jakob disease, prions, bovine spongiform encephalopathy, scrapie, BSE, CJD, CWD, TME, and TSE. Last Updated: 17 Apr 01 . . a project of the Sperling Biomedical Foundation . Note: news, policy, commentar, medicine have moved to new site The Official Mad Cow Disease Home Page You are what you eat: now serving number Bovine-CJD: might you already have it? ... Visit charity pages Early warnings: insomnia, memory loss, depression, anxiety, withdrawal, fearfulness) News archives Best links Search site 3D prions ... Science archives NEWS 2001 has moved Apr 17.. Webmaster: the next generation Apr 28.. Global TSE News Mar 24.. Slaughter on suspicion Mar 17.. Second epidemic raging Feb 27.. Canada censors scientists Feb 16.. Diagnostic news Feb 12.. Cosmetics ban on 13 countries Feb 11.. Genetically modified foods Feb 09.. Bogus BSE in Brazil? Jan 30.. Texas cattle quarantined Jan 13.. FDA scolds feed mills Jan 08.. Canadian concerns Jan 03.. FDA issues vaccine alert NEWS 2000... Dec 28..

95. Monthly Creutzfeldt Jacob Disease Statistics Monthly Creutzfeldt Jacob disease statistics. The Department of Health is today issuing the latest information about the numbers of known cases of http://www.prnewswire.co.uk/cgi/news/release?id=90106

96. EID V3 N1: The Epidemiology Of Creutzfeldt-Jakob Disease In Canada: A Review Of Creutzfeldt Jacob disease clinical analysis of a consecutive series of 230 neuropathologically verified cases. Ann Neurol 1986;20597602. Will, RG. http://www.cdc.gov/ncidod/eid/vol3no1/stratton.htm

Dispatches The Epidemiology of Creutzfeldt-Jakob Disease in Canada: A Review of Mortality Data Download Article Creutzfeldt-Jakob disease (CJD), and particularly its transmissibility through blood and blood products, has become a focus of concern in Canada. The recent identification of new variant CJD led to a review of the Canadian mortality database to identify any clustering of CJD by age, sex, or geographic location. The study by Holman and colleagues (1), which uses mortality data and active surveillance methods, has provided further information on the epidemiology of Creutzfeldt-Jacob disease (CJD). The study concluded that the incidence of the disease in the United States has remained stable and is similar to crude incidence worldwide at about one case per million annually. In addition, the study found no evidence that new variant CJD is present in the U.S. population. These findings are of interest because the epidemiology of CJD in Canada is not well described, and concerns have been raised there about the transmissibility of CJD through transfusion of blood and blood products or through tissue and organ transplants. In addition, many Canadians travel to and from the United Kingdom, where new variant CJD was first identified and linked to the bovine spongiform encephalopathy epidemic (2). We report here our findings on the epidemiology of CJD in Canada, which are derived from published mortality data (underlying cause of death by standard 5-year age group and sex, for all Canadian residents). The Statistics Canada mortality reports for the years 1979 to 1993 were reviewed for CJD deaths by sex and age group for each province and territory. Reports before 1979 were not used because CJD (ICD-9 code 46.1) was not listed as a cause of death before this time.

97. Alzheimer's Society Information Sheet - What Is CJD? The bestknown prion disease is Creutzfeldt-Jakob disease, or CJD. These include Creutzfeldt-Jakob disease, as well as two extremely rare inherited http://www.alzheimers.org.uk/Facts_about_dementia/What_is_dementia/info_CJD.htm

breadCrumbs("http://www.alzheimers.org.uk","/","index.htm","crumb","crumb","crumb","0"); Helpline / Ask a question Contact us Make a donation Membership ... Fundraising events What is Creutzfeldt-Jakob disease (CJD)? Prions are infectious agents that attack the central nervous system and then invade the brain, causing dementia. The best-known prion disease is Creutzfeldt-Jakob disease, or CJD. This information sheet provides an overview of the symptoms and different types of CJD. Prion disease Prions are abnormal forms of protein that are extremely hardy and cannot be eradicated by normal sterilisation procedures. Their presence in the brain results in spongiform encephalopathy, so-called because areas of the brain where cells have died take on a sponge-like appearance when viewed under the microscope. There are a number of prion diseases that affect humans. These include Creutzfeldt-Jakob disease, as well as two extremely rare inherited diseases, Gerstmann-Straussler-Scheinker disease (GSS) and fatal familial insomnia (FFI). Creutzfeldt-Jakob disease (CJD) Creutzfeldt-Jakob disease was first reported by two German doctors (Creutzfeldt and Jakob) in 1920.

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