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         Creutzfeldt-jacob Disease:     more detail
  1. Chronic neurological diseases: Subacute Sclerosing Panencephalitis, progressive multifocal Leukoencephalopathy, Kuru, Creutzfeldt-Jakob Disease by Jacob A Brody, 1976

21. CREUTZFELDT-JAKOB DISEASE IN CANADA - CCDR Volume 22-08 - Health Canada
Figure 4 Ageadjusted mortality rate for creutzfeldt-jacob disease, Canada, creutzfeldt-jacob disease clinical analysis of a consecutive series of 230
http://www.phac-aspc.gc.ca/publicat/ccdr-rmtc/96vol22/dr2208ea.html
Volume 22-08
15 April 1996
Table of Contents
CREUTZFELDT-JAKOB DISEASE IN CANADA
Creutzfeldt-Jakob disease (CJD) is a rare and fatal neuro-degenerative disease. The clinical presentation includes dementia, myoclonus and progressive motor dysfunction. Death usually occurs within a year of the onset of symptoms. CJD is transmitted in humans in rare instances, and the disease can be dormant for as long as 30 years. The average age of onset is 60 years, but there are recorded instances of onset as early as 16 years, and as old as 80 (1-5) . The causative agent has not been identified, but slow viruses of the central nervous system (5) and infective proteinaceous particles or prions (4) have both been postulated as the agent responsible for the disease. There is no current treatment for CJD. Diagnosis is based on clinical signs, characteristic EEG changes, brain biopsy and postmortem histopathologic findings (1,6) . Genetic predisposition to the disease is associated with mutations in the prion protein gene. Concerns have been raised regarding the possible transmissibility of CJD through transfusion of blood or organ transplants. In response to this, the following review of Canadian mortality data has been undertaken to search for clustering of CJD by age, sex or geography.

22. ACLS -- Sign In Page
Keywords creutzfeldtjacob disease, spongiform encephalopathy, prion, creutzfeldt-jacob disease (CJD) is a rare and transmissible neurological disorder
http://www.annclinlabsci.org/cgi/content/full/31/2/211
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A Cluster of Creutzfeldt-Jacob Disease Patients from Nassau County, New York, USA
Adikari and Farmer Ann Clin Lab Sci.
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23. Creutzfeldt-Jacob Disease Cases
The bovine spongiform encephalopathy and the variant creutzfeldtjacob disease cases in the Mediterranean countries.
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The bovine spongiform encephalopathy (BSE) and the variant Creutzfeldt-Jacob disease (VCJD) cases in the Mediterranean countries. Factors that influence meat safety during the contemporary cattle slaughtering process
Shortly after the identification of Bovine Spongiform Encephalopathy (BSE) in cattle, concerns emerged that this disease could be transmitted to humans consuming meat or meat products. Such concerns have been exacerbated by confirmation that the infectious agent, a prion isolated from BSE-infected cattle, shares a number of characteristic biological and structural features with the infectious agent of variant Creutzfeldt-Jacob disease (vCJD) in humans.

24. Disease - Creutzfeldt-Jacob Disease - Hartford, Connecticut
Disease creutzfeldt-jacob disease - courtesy of Saint Francis Care of Hartford, Connecticut, contemporary medicine with major clinical concentrations in
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Disease - Creutzfeldt-Jacob disease
Creuztfeldt-Jakob disease
Central nervous system
Definition: Creutzfeldt-Jacob disease is a disorder involving rapid decrease of mental function and movement. These are abnormalities believed to be caused by damage done to the brain by a protein called a prion. This protein folds abnormally, and seems to encourage other proteins to become similarly misshapen, affecting their ability to function. Alternative Names: Transmissible Spongiform Encephalopathy; New variant CJD - "the human form of mad cow disease" Causes And Risk: Creutzfeldt-Jakob disease can occur sporadically (for no known reason), as a result of exposure to contaminated products. Rarely, it can be genetically inherited. The disorder itself is rare, occurring in about 1 out of 1 million people. It usually first appears in midlife, beginning between ages 20 and 70, with average age at onset of symptoms in the late 50s. However, some cases have occurred in adolescents who have received

25. Familial Creutzfeldt-Jacob Disease - General Practice Notebook
familial creutzfeldtjacob disease. The familial forms of Creutzfeldt-Jacob (CJD) disease. have a wide spectrum of clinical features
http://www.gpnotebook.co.uk/cache/1047199817.htm
familial Creutzfeldt-Jacob disease The familial forms of Creutzfeldt-Jacob (CJD) disease:
  • have a wide spectrum of clinical features may vary in its clinical features between and within families have an autosomal dominant mode of inheritence account for 10% of cases of CJD
In general:
  • familial CJD presents earlier, from 40 years on the clinical course is longer

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26. Sporadic Creutzfeldt-Jacob Disease - General Practice Notebook
sporadic creutzfeldtjacob disease. Sporadic CJD accounts for over 90% of cases of human prion disease. The disease occurs worldwide with an annual
http://www.gpnotebook.co.uk/cache/1295319113.htm
sporadic Creutzfeldt-Jacob disease Sporadic CJD accounts for over 90% of cases of human prion disease. The disease occurs worldwide with an annual incidence of one case per million population. There are no known environmental risk factors. Most patients with sporadic CJD are homozygous for methionine at the polymorphic position 129 in the prion protein.
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27. The Dictionary Of Cell And Molecular Biology - Online!
creutzfeldtjacob disease. Rare fatal presenile dementia of humans, similar to kuru and other slow viruses. Method of transmission unknown.
http://www.mblab.gla.ac.uk/~julian/dict2.cgi?1578

28. Millipore - Applications Bibliography - Investigation Of Variant Creutzfeldt-Jac
Title, Investigation of variant creutzfeldtjacob disease and other human prion diseases with tonsil biopsy samples. Author, AF Hill et al.
http://www.millipore.com/bibliography.nsf/docs/Imm137

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... Manage Account Settings Millipore Applications Bibliography Title: Investigation of variant Creutzfeldt-Jacob disease and other human prion diseases with tonsil biopsy samples Author: A.F. Hill et al. Citation: Lancet, 353, 9148, 183(1), Jan. 16, 1999 Additional Information: Immobilon P Application: Immunoassay Please note: This information is provided to you for technical reference. A reprint of the document cited is available from the publisher or from your local library and is not available from Millipore. For further assistance, please contact Technical Service. English Fran§ais Italiano ... Feedback

29. GE Creutzfeldt-Jacob Disease
Ken Follett. Hyperfiction. Gab Eti Orgrease, Bullamanka, NY, Preservation of Single Occupancy Structures.
http://www.geocities.com/SoHo/Cafe/5836/gecjd.html
Creutzfeldt-Jacob Disease
There was a letter in my mailbox last month about a case of spongiform encephalopathy a.k.a. Creutzfeldt-Jacob disease in a guy who ate squirrel brains. I should make clear, Creutzfeldt-Jakob disease is NOT Mad Cow Disease. MCD (bovine spongiform encephalopathy) is one of several prion diseases. A statistical excess of CJD has been seen in people who ate squirrel brains. That is, in a relatively small population there were more cases of CJD than one would expect, and the small population in question ate squirrel brains. Does this mean that squirrels have prion diseases that are contagious to humans? Shit if I know? There was no evidence that the squirrels in question had a prion disease. In fact, there's no evidence that squirrels ever get prion diseases. On the other hand, nobody has looked very closely at squirrel brains. Was this an encyclopedic blip? Who knows? With rare diseases like this, blips happen, and can be real bitches to sort out. CJD occurs in one in a million. There are approximately 250 cases of CJD in the USA per year. It would therefore not be unexpected to see a case of CJD in a human being who consumed an excessive number of squirrel brains. Indeed, it would be remarkable to NOT see any cases of CJD in squirrel brain eaters. More people than you would suspect eat squirrel brains. It is considered a delicacy. Apparently squirrel brains are very common in some parts of the country.

30. Forum On Nutrition And Exercise: Creutzfeldt-Jacob Disease
About creutzfeldtjacob disease I know use of HGH in healthy humans was banned after 4 people contracted creutzfeldt-jacob disease.
http://www.thebody.com/Forums/AIDS/Nutrition/Archive/Alternative/Q150003.html
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Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered. Ask the Experts about Nutrition and Exercise
Creutzfeldt-Jacob Disease
Aug 30, 2003 Hi Nelson Great work you are doing here! About Creutzfeldt-Jacob Disease... I know use of HGH in healthy humans was banned after 4 people contracted Creutzfeldt-Jacob Disease. Does the HGH that is now manufactured totally free of the risk of this and other viruses? Response from Mr. Vergel Yes, thank GOD! Nelson
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31. Creutzfeldt-Jacob Disease (CJD) : Report Of 10 Cases From North India. Singhal B
Neurol India is an peerreviewed biomedical periodical of Neurological Society of India.
http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2002;volume=50;iss

32. Creutzfeldt-Jacob Disease, News Bureau - University Of Pittsburgh Medical Center
creutzfeldtjacob disease INFORMATIONAL RELEASE. PITTSBURGH, June 12, 2002 — In the interest of public disclosure, University of Pittsburgh Medical Center
http://newsbureau.upmc.com/director/CjdRelease.htm
Contact: Jane Duffield Patients and medical professionals may call 1-800-533-UPMC (8762) for more information. Telephone: Fax: CREUTZFELDT-JACOB DISEASE INFORMATIONAL RELEASE PITTSBURGH, June 12, 2002 CJD In April 2001 a patient had surgery at UPMC Presbyterian to treat a condition of the nervous system. The surgical instruments were sterilized with standard procedures following the surgery. In the first quarter of 2002, the patient died from progression of a neurological disorder. Following the patient's death it was determined upon autopsy, for the first time, that the patient had Creutzfeldt-Jacob Disease (CJD). This disease is believed to be transmitted by an infectious protein, or prion. Prions may not be eliminated by standard instrument sterilization processes. The instruments used in the patient's surgery presented an extremely low risk of transmitting CJD to patients who had neurosurgery with these instruments during the period from April 17, 2001 to April 6, 2002. There are only a very small number of reported cases of CJD developing after exposure of a patient to instruments used in a prior surgery on an individual with CJD, the most recent being in Europe in 1976. No such cases have been reported in the United States since the adoption of the standard sterilization techniques which were in use at the time of the patient's operation in April of 2001.

33. Gastroenterology Nursing - UserLogin
creutzfeldtjacob disease/Mad Cow Disease A Helpless Vigil The incidence is questionable because creutzfeldt-jacob disease is not a Centers of Disease
http://www.gastroenterologynursing.com/pt/re/gastronurse/fulltext.00001610-20050
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34. CSMLS / SCSLM : Continuing Education/ Éducation Permanete: Creutzfeldt-Jacob Di
creutzfeldtjacob disease 9870. Level Advanced, Credits 1.0 CPS/ART credits 15 PEP hours. Regular mail is used for submitting assignments Assignment
http://www.csmls.org/CE/CE_course_details.cfm?ID=9870&&CFID=916389-471

35. The Bioline EPrints Archive - Creutzfeldt-Jacob Disease (CJD) : Report Of 10 Cas
creutzfeldtjacob disease (CJD) Report of 10 Cases from North India. Singhal, BS (2002) creutzfeldt-jacob disease (CJD) Report of 10 Cases from North
http://bioline.utsc.utoronto.ca/archive/00000361/
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Creutzfeldt-Jacob Disease (CJD) : Report of 10 Cases from North India
Singhal, B.S. Creutzfeldt-Jacob Disease (CJD) : Report of 10 Cases from North India Neurology India Full text available as:
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Abstract
I read with interest the article on 'Creutz-Jacob Disease (CJD) : Report of 10 cases from North India'.1 As the authors have remarked, CJD is being increasingly reported from various regions in India. CJD Registry at NIMHANS initiated by Shankar and Satish Chandra2 is a step in the right direction to know about the prevalence of CJD in India. Item Type: Journal (Paginated) Keywords: Subjects: Medicine Neurology ID Code: Deposited By: Sun, Yibing Deposited On: 12 June 2003 Alternative Locations: http://www.bioline.org.br/abstract?ni02035 http://www.neurologyindia.com/vol50-1/FullArticles/matter.pdf Repository Contact Information © 2005 Bioline International

36. Creutzfeldt-Jacob Disease Obituary
creutzfeldtjacob disease Obituary. In the Sunday May 18 New York Times an obituary was published for Joanie Westie, a Big Star in the World of Roller
http://www.organicconsumers.org/cjdobit.html
Creutzfeldt-Jacob disease Obituary
In the Sunday May 18 New York Times an obituary was published for Joanie Westie, a "Big Star in the World of Roller Derbies" who died May 10 at age 62. The interesting part is that, according to her husband, Nick Scopas, she died of a "rare brain disease", you guessed it, Creutzfeldt-Jacob disease. The Times makes no further mention of the cause of death, nor does it remind its readers that this is the same disease that caused such a furor among the French when a few of their citizens died of it. The reason for the French ire was of course that scientists believe that CJ disease is linked to Mad Cow disease (bovine spongiform encephalopathy) The furor resulted in the banning of British beef from import into the EU and the collapse of the British beef industry. This was reported on the front page of the New York Times. Is it that NYT editors don't read their own articles, or are they just being loyal protectors for agri-business interests? And I also wonder if the family is aware of the CJ - Mad Cow connection? If not, may be somebody in California should tell them (or their attorney). They live in Hayward California, near San Francisco. In addition to her husband, Ms. Westie was survived by two step children - Tracy Munoz of Hayward and Nick Scopas Jr. of Manteca CA.

37. A Cluster Of Creutzfeldt-Jacob Disease Patients From Nassau County
A Cluster of creutzfeldtjacob disease Patients from Nassau County, New York, USA.
http://www.organicconsumers.org/madcow/cluster501.cfm
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A Cluster of Creutzfeldt-Jacob Disease Patients from Nassau County, New York, USA
February, 2001 Annals of Clinical and Laboratory Science Vol. 31 no. 2 p. 211-2 Creutzfeldt-Jacob Disease (CJD) is a rare and transmissible neurological disorder, which has been increasing in frequency in the United States over the past two decades. [...] We report 7 cases of CJD from North Shore University Hospital, a community-based teaching institution that serves Nassau County on Long Island, NY. These cases were diagnosed and died during the 12-mo period between mid-June 1999 to midJune 2000... These data suggest a CJD death rate in Nassau County... approximately 6 times the national rate. During the previous 1-yr period, no case of CJD was diagnosed in our laboratory [...] The authors are concerned that the number of CJD cases in our catchment area appears to have increased dramatically during the 12-mo period. [...] News Campaigns GE Food Organics ... Site Map Organic Consumers Association
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38. BBC News | HEALTH | VCJD And BSE - The Link
vCJD is the human form of mad cow disease. creutzfeldtjacob disease is an untreatable and invariably fatal disease in humans which is similar to BSE in
http://news.bbc.co.uk/2/hi/health/967133.stm
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Friday, 20 October, 2000, 16:44 GMT 17:44 UK vCJD and BSE - the link
vCJD is the human form of mad cow disease
Creutzfeldt-Jacob disease is an untreatable and invariably fatal disease in humans which is similar to BSE in cattle and scrapie in sheep. The diseases are together called "spongiform encephalopathies", because they all reduce the brain to the same spongy appearance, with gaps appearing within the tissue. The type of CJD associated with BSE in cattle is termed "variant CJD", and is distinctively different from standard CJD - which emerges in between 25 and 60 UK adults each year, normally in people aged over 55. Variant CJD began to emerge and be diagnosed in the mid-1990s - there have been 73 confirmed cases so far, with just under a dozen probable cases which have yet to be confirmed, either because the patient is still alive, or because the post mortem has yet to take place.
vCJD produces gaps inside the brain
It seems to be capable of developing in much younger people than standard CJD.

39. Healthinmind/Menthal Health Disorders/Dementias/Creutzfeld-Jacob
creutzfeldtjacob disease. This type of dementia, like Alzheimer s or Huntington s, is caused by organic changes in the brain, but in this case the changes
http://healthinmind.com/english/creutz-ja.htm

Healthinmind
Mental Health Disorders Cognitive Disorders Dementias Creutzfeldt-Jacob Disease
The Creutzfeldt-Jacob Foundation web site contains much additional information. Last updated

40. NewsFromRussia.Com Japan: First Human Victim Of Mad Cow Disease
The human variant of creutzfeldtjacob disease has only been confirmed or deemed probable in 167 other people worldwide, virtually all of them in Britain
http://newsfromrussia.com/science/2005/02/04/58098.html
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Japan: first human victim of mad cow disease
A Japanese man who died in December is believed to be the first person in Japan to die of the human variant of mad cow disease , Japanese Health Ministry officials said.
The man, said to be in his 50s, is believed to have become infected with the disease during a month-long visit to Britain in 1989, the officials said.
The man developed typical symptoms of the human variant Creutzfeldt-Jakob Disease in December, 2001, the official said.
The Health Ministry said there were no concerns of any others infections from this case since there have been no instances of human to human infections, reports CNN News.

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