41. UNTSHC Clinic Digital Library general Cardiovascular Disorders Clinical resources Polyangiitis Overlap Syndrome Chapter 50 Diffuse connective tissue Disease Table of contents http://unthsc-dl.slis.ua.edu/clinical/rheumatology/autoimmune/vasculitides/syste

Clinical Resources by Topic: Cardiovascular Disorders Polyangiitis Overlap Syndrome Clinical Resources Atlases Pathology Miscellaneous Resources See also: General Cardiovascular Disorders Clinical Resources Polyangiitis Overlap Syndrome Patient/Family Resources Harrison's Principles of Internal Medicine 16th Ed.-2005: Table of contents Lewis Library subscription INFO Chapter 306. The Vasculitis Syndromes: Table of contents Introduction: Access document Polyangiitis Overlap Syndromes: Access document Principles of Treatment: Access document Further Reading: Access document Harris: Kelley's Textbook of Rheumatology 7th Ed.-2005 (MD Consult): Table of contents Lewis Library subscription INFO Section XII - Vasculitis: Access document Chapter 81 - The Classification and Epidemiology of Systemic Vasculitis: Access document Introduction: Access document The First Modern Case: "Periarteritis Nodosa": Access document Historic Attempts at Classification and Nomenclature: Access document Epidemiology: Access document References: Access document Chapter 83 - Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Access document Introduction: Access document Antineutrophil Cytoplasmic Antibody: Access document Microscopic Polyangiitis: Access document References: Access document Habif: Clinical Dermatology 4th Ed.-2004 (MD Consult):

42. WD: Disorders Of Systemic, Metabolic Or Environmental Origin, Etc. Resource guides WD 301 Vis tilhørende emneord; autoimmune diseases (general) Collagen diseases and other connective tissue diseases (general) WD 375 http://www.nsk.dnlb.dk/find_fag.php?katalog=WD

43. Rural Nurse Organization Clinic Digital Library general Immunology Patient/Family resources Systemic Lupus Erythematosus Clinical autoimmune Disorders of connective tissue Table of contents http://ruralnurseorganization-dl.slis.ua.edu/patientinfo/immunology/autoimmune/s

Patient/Family Resources by Topic: Immunology Systemic Lupus Erythematosus Patient/Family Resources Pediatrics Spanish Miscellaneous See also: General Immunology Patient/Family Resources Systemic Lupus Erythematosus Clinical Resources Arthritis Foundation: Homepage Disease Center: List of documents Lupus/Systemic Lupus Erythematosus (SLE) Access document American College of Rheumatology: Homepage Patient Information: List of documents Systemic Lupus Erythematosus: Access document American Academy of Dermatology: Homepage Public Resource Center: Table of contents Pamphlets List of documents Lupus and the Skin Access document National Institute of Diabetes and Digestive and Kidney Diseases: Homepage Kidney Diseases: Table of contents A-Z List of Topics and Titles: List of documents Lupus Nephritis: Access document American Academy of Family Physicians (familydoctor.org): Homepage Self Care Flowcharts: List of documents Skin Rashes and Other Changes: Access document University of Birmingham (U.K.) Dept of Rheumatology: Homepage Patient Information: List of documents Lupus: Table of contents Arthritis Help: A Primer on Rheumatic Diseases: Table of contents A Few Definitions Access document General Features of Inflammatory Arthritis Access document Connective Tissue Diseases Access document Children with Arthritis Access document Treatments Access document American Pain Foundation: Homepage Consumer Health Information: List of documents Connective Tissue Diseases: Access document MedlinePlus and the Patient Education Institute: Homepage Interactive Health Tutorials:

44. Rural Nurse Organization Clinic Digital Library Chapter 50 Diffuse connective tissue Disease Table of contents Pediatricsresources See also general Pediatrics resources http://ruralnurseorganization-dl.slis.ua.edu/clinical/rheumatology/autoimmune/ar

Clinical Resources by Topic: Rheumatology Rheumatoid Arthritis Clinical Resources Emergency Pediatrics Geriatrics Atlases ... Miscellaneous Resources See also: Musculoskeletal Clinical Procedure Resources General Rheumatology Clinical Resources Rheumatoid Arthritis Patient/Family Resources Wheeless' Textbook of Orthopaedics: Table of contents Rheumatoid Arthritis: List of documents American Rheumatism Association Diagnostic Criteria for R.A.: Access document Pathogenesis of RA: Access document Differential Diagnosis of Rheumatoid Arthritis: Access document RA: Clinical Aspects: Access document Stages of Rheumatoid Arthritis: Access document Cervical Spine in RA: Access document Rheumatoid Hand: Access document Rheumatoid Wrist: Access document Elbow in RA Patient: Access document Hip Joint in Rheumatoid Arthritis: Access document Rheumatoid Foot: Access document Laboratory Aspects of RA: Access document Radiographic Aspects of RA: Access document RA: Medical Management: Access document The Merck Manual 17th Ed.-1999: Table of contents Chapter 50: Diffuse Connective Tissue Disease: Table of contents Rheumatoid Arthritis: Access document Family Practice Handbook 4th Ed.-2001:

45. 800 Disease Links Reference Tools Directories general resources Disease Specific resources http//rheumb.bham.ac.uk/ctd.htmlconnective tissue diseases connective http://www.mysteries-megasite.com/main/bigsearch/disease-3.html

Disease Database Diseases Part 3 Go to Frames! Break Out of Frames Search Mystery Links Home Page-Site Guide ... http://www.who.int/health-topics/idindex.htm WHO/OMS: Infectious diseases Last update: 21-Dec-2001 African trypanosomiasis Buruli Ulcer Chagas disease Cholera... http://rarediseases.info.nih.gov/ Office of Rare Diseases - Welcome to our Website Office of Rare Diseases Skip Navigation Links... http://www.aasld.org/ American Association for the Study of Liver Diseases (AASLD... http://www.asam.org/jol/journal.htm Journal of Addictive Diseases (home page) Journal of Addictive Diseases Table of Contents and Abstracts Journal of Addictive Diseases is the official journal of the American Society of Addiction Medicine and is published quarterly and provided free to ASAM members. The Journal and a... http://www.stdjournal.com/ Lippincott Williams Wilkins - Sexually Transmitted Diseases This web page uses frames, but your browser doesn't support them... http://www.lib.uiowa.edu/hardin/md/micro.html http://www.biomedcentral.com/1471-2334/ BMC Infectious Diseases 20 February, 2002BMC Infectious DiseasesPublishing peer reviewed original research papers with open access (Submit a manuscript) BMC Infectious DiseasesBioMed... http://www.health.gov.au/pubhlth/cdi/cdihtml.htm

46. Autoimmune Disorders A general autoimmune disease in which antibodies attack a number of different scleroderma affects the connective tissue. autoimmune hemolytic anemia. http://www.chclibrary.org/micromed/00039060.html

Main Search Index Definition Description Causes ... Resources Autoimmune disorders Definition Autoimmune disorders are conditions in which a person's immune system attacks the body's own cells, causing tissue destruction. Description Autoimmunity is accepted as the cause of a wide range of disorders, and it is suspected to be responsible for many more. Autoimmune diseases are classified as either general, in which the autoimmune reaction takes place simultaneously in a number of tissues, or organ specific, in which the autoimmune reaction targets a single organ. Autoimmune disorders include the following: Systemic lupus erythematosus . A general autoimmune disease in which antibodies attack a number of different tissues. The disease recurs periodically and is seen mainly in young and middle-aged women. Rheumatoid arthritis . Occurs when the immune system attacks and destroys the tissues that line bone joints and cartilage. The disease occurs throughout the body, although some joints may be more affected than others. Goodpasture's syndrome . Occurs when antibodies are deposited in the membranes of both the lung and kidneys, causing both inflammation of kidney glomerulus (

47. Questions And Answers About Autoimmunity Because autoimmune diseases can affect almost any organ or system of the body, In more severe forms, connective tissue can build up in the kidneys, http://www.niams.nih.gov/hi/topics/autoimmune/autoimmunity.htm

En español Health Information Health Topics Order Publications Studies with Patients Patient Research Registries ... NIAMS Coalition Members Health Topics PDF Version Publication Date January 2002 Questions and Answers About Autoimmunity This booklet answers questions about autoimmunity. To learn more about autoimmunity, your immune system, or autoimmune diseases, speak with your doctor. You can also check out the Appendices below. What Is Autoimmunity? What Causes Autoimmunity? What Kinds of Problems Are Caused by Autoimmunity? How Are Autoimmune Diseases Diagnosed? ... Appendix II: Glossary of Diseases What Is Automimmunity? When your body is attackedperhaps by a virus or germs on a nail you stepped onyour immune system defends you. It sees and kills the germs that might hurt you. But when the system doesn't work right, this process can cause harm. Immune cells can mistake your body's own cells as invaders and attack them. This "friendly fire" can affect almost any part of the body. It can sometimes affect many parts of the body at once. This is called autoimmunity (meaning self-immunity). What Causes Autoimmunity?

48. Questions And Answers About Arthritis And Rheumatic Diseases Some rheumatic diseases are described as connective tissue diseases because Others are known as autoimmune diseases because they occur when the immune http://www.niams.nih.gov/hi/topics/arthritis/artrheu.htm

Health Information Health Topics Order Publications Studies with Patients Patient Research Registries ... NIAMS Coalition Members Health Topics PDF version Publication Date February 2002 Questions and Answers About Arthritis and Rheumatic Diseases This fact sheet answers basic questions about arthritis and rheumatic diseases. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has other fact sheets and booklets that provide more information about specific forms of arthritis and rheumatic diseases. NIAMS also has information about exercise and arthritis, pain and arthritis, and diet and arthritis. If you have further questions after reading this information, you may wish to discuss them with your doctor. What Are Rheumatic Diseases and What Is Arthritis? Examples of Rheumatic Diseases What Causes Rheumatic Disease? Who Is Affected by Arthritis and Rheumatic Conditions? ... Where Can People Find More Information About Arthritis and Rheumatic Diseases? What Are Rheumatic Diseases and What Is Arthritis? Rheumatic diseases are characterized by inflammation (signs are redness and/or heat, swelling, and pain) and loss of function of one or more connecting or supporting structures of the body. They especially affect joints, tendons, ligaments, bones, and muscles. Common symptoms are pain, swelling, and stiffness. Some rheumatic diseases can also involve internal organs. There are more than 100 rheumatic diseases.

49. HealthyNJ--Information For Healthy Living--Scleroderma • New Jersey resources The symptoms may overlap with those of several other connective tissue disorders,......Additional Information. • general http://www.healthynj.org/dis-con/scleroderma/main.htm

Additional Information General Description New Jersey Resources Recommended Web Sites Patient Education ... PubMED Search Scleroderma (systemic sclerosis) is a chronic disorder characterized by degenerative changes and scarring in the skin, joints, and internal organs and by blood vessel abnormalities. The cause of scleroderma is not known. The disorder is 4 times more common in women than in men and is rare in children. Symptoms of scleroderma may occur as part of mixed connective tissue disease, and some people with mixed connective tissue disease develop severe scleroderma. Symptoms The usual initial symptom of scleroderma is swelling, then thickening and tightening of the skin at the ends of the fingers. Raynaud's phenomenon, in which the fingers suddenly become very pale and tingle or become numb and/or painful in response to cold or emotional upset is also common. Fingers typically become bluish as they warm up. Heartburn, difficulty in swallowing, and shortness of breath are occasionally the first symptoms of scleroderma. Aches and pains in several joints often accompany early symptoms. Sometimes polymyositis, with its accompanying muscle pain and weakness, develops.

50. Understanding Autoimmune Diseases Printer Friendly Version. Understanding autoimmune diseases In more severeforms, connective tissue can build up in the kidneys, lungs, heart, http://www.clevelandclinic.org/health/health-info/docs/1000/1029.asp?index=5865&

51. Anemia, Hemolytic, Cold Antibody Disorder Subdivisions. general Discussion. resources. For a Complete Report American autoimmune Related diseases Association, Inc. 22100 Gratiot Avenue http://my.webmd.com/hw/anemia/nord723.asp

var guid_source = ""; var guid_source_id = ""; //unused var encodedurl = ""; WebMD Today Home WebMD News Center XML News via RSS Member Services WebMD University My WebMD Find a Physician Medical Info Check Symptoms Medical Library Health Tools Clinical Trials ... Women, Men, Lifestyle Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Anemia, Hemolytic, Cold Antibody Important It is possible that the main title of the report Anemia, Hemolytic, Cold Antibody is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Anemia, Autoimmune Hemolytic Cold Agglutinin Disease Cold Antibody Disease Disorder Subdivisions None General Discussion Cold Antibody Hemolytic Anemia is a rare autoimmune disorder characterized by the premature destruction of red blood cells by the body's natural defenses against invading organisms (antibodies). Normally, the red blood cells have a life span of approximately 120 days before they are removed by the spleen. In individuals with Cold Antibody Hemolytic Anemia, the red blood cells are destroyed prematurely and bone marrow production of new cells can no longer compensate for their loss. The severity of the anemia is determined by the length of time that the red blood cells survive and by the capacity of the bone marrow to continue new red blood cell production. Immune Hemolytic Anemias may be subdivided by the temperatures at which the antibodies destroy red blood cells. As its name implies, Cold Antibody Hemolytic Anemia occurs at temperatures of approximately to 10 degrees centigrade (while Warm Antibody Hemolytic Anemia, for example, occurs at temperatures of 37 degrees or higher).

52. Arthritis Symptoms - Signs - Complaints - Causes - Diagnosis autoimmune diseases, such as lupus, rheumatoid arthritis, and Sjögren s group of diseases complicated by the abnormal growth of connective tissue which http://arthritis.about.com/od/arthritislearnthebasics/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a02' About Arthritis Symptoms / Diagnosis Arthritis Essentials Arthritis Symptoms Is It Arthritis? ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/7.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Arthritis newsletter! See Online Courses Search Arthritis Arthritis: Symptoms - Signs - Complaints - Causes - Diagnosis - A to Z Information, articles and resources on the signs and symptoms of arthritis. Learn more on controlling the common complaints and other problems of having arthritis. Learn more about the causes and diagnosis of the various types of arthritis. Alphabetical Recent "I Think I Have Arthritis. Now What?" When the first signs and symptoms of arthritis appear, confusion and questions arise. Anemia - Is anemia commonly associated with chronic arthritis? Anemia is often a symptom associated with chronic arthritis. Ankylosing Spondylitis Screening Quiz Ankylosing spondylitis is one of the rheumatic diseases which belong to the group of conditions known as spondyloarthopathies. Statistics reveal that about 129 out of 100,000 people in the United States have ankylosing spondylitis. Do you have symptoms associated with ankylosing spondylitis? Anti-CCP - What is anti-CCP?

53. Types Of Arthritis - Information - Causes - Symptoms - Treatment Options The symptoms of fibromyalgia can overlap with autoimmune diseases and other an underlying disease, most commonly one of the connective tissue diseases. http://arthritis.about.com/od/diseasesandconditions/

zJs=10 zJs=11 zJs=12 zJs=13 zc(5,'jsc',zJs,9999999,'') zfs=0;zCMt='a02' About Arthritis Types of Arthritis Arthritis Essentials Arthritis Symptoms Is It Arthritis? ... Help zau(256,140,140,'el','http://z.about.com/0/ip/417/C.htm','');w(xb+xb+' ');zau(256,140,140,'von','http://z.about.com/0/ip/496/7.htm','');w(xb+xb); FREE Newsletter Sign Up Now for the Arthritis newsletter! See Online Courses Search Arthritis Arthritis: The Types of Arthritis - Related Conditions - A to Z There are over 100 types of arthritis and related conditions. Information about the cause, symptoms, diagnosis and treatment for the most common types of arthritis. Alphabetical Recent Arthritis Screening Quiz Have you had persistent joint pain and you don't know the cause? Do you think it may be arthritis? Have you discounted the possibility of it being arthritis because you think arthritis is just an old-person's disease? Take the Arthritis Screening Quiz. Osteoarthritis Screening Quiz Osteoarthritis is also known as "wear-and-tear" arthritis. It is typically seen as a primary disease in older people but can occur as a secondary condition in younger people. Injury, occupation, excess weight, and genetics are among the factors which cause the cartilage of a joint to wear away. Take our Osteoarthritis Screening Quiz. Rheumatoid Arthritis Screening Quiz Early diagnosis of rheumatoid arthritis and early, aggressive treatment can help prevent joint damage and deformity. A combination of diagnostic tests, physical examination, and x-ray evidence confirms the diagnosis of rheumatoid arthritis. Take our screening quiz and if you suspect rheumatoid arthritis, consult a rheumatologist.

54. Rheumatic Diseases And Arthritis - HealingWell.com Some rheumatic diseases are described as connective tissue diseases because Others are known as autoimmune diseases because they are caused by a problem http://www.healingwell.com/library/arthritis/info2.asp

HOME VIDEOS RESOURCES NEWSLETTER ... SEARCH Search Site: Search Archives: HealingWell Conditions Arthritis Library Article Rheumatic Diseases and Arthritis What Are Rheumatic Diseases and What Is Arthritis? There are more than 100 rheumatic diseases. These diseases may cause pain, stiffness, and swelling in joints and other supporting structures of the body such as muscles, tendons, ligaments, and bones. Some rheumatic diseases can also affect other parts of the body, including various internal organs. Many people use the word “arthritis” to refer to all rheumatic diseases. However, the word literally means joint inflammation; that is, swelling, redness, heat, and pain caused by tissue injury or disease in the joint. The many different kinds of arthritis comprise just a portion of the rheumatic diseases. Some rheumatic diseases are described as connective tissue diseases because they affect the body’s connective tissue—the supporting framework of the body and its internal organs. Others are known as autoimmune diseases because they are caused by a problem in which the immune system harms the body’s own healthy tissues. Examples of some rheumatic diseases are provided on the next page. Examples of Rheumatic Diseases Osteoarthritis —Also known as degenerative joint disease, osteoarthritis is the most common type of arthritis, affecting an estimated 20.7 million adults in the United States. Osteoarthritis primarily affects cartilage, which is the tissue that cushions the ends of bones within the joint. Osteoarthritis occurs when cartilage begins to fray, wear, and decay. In extreme cases, the cartilage may wear away entirely, leaving a bone-on-bone joint. Bony spurs (pointy bulges of bone) may form at the edges of the joint. Osteoarthritis can cause joint pain, reduced joint motion, loss of function, and disability. Disability results most often when the disease affects the spine and the weight-bearing joints (the knees and hips).

55. The Lupus Lady's Autoimmune Disease Support I was then diagnosed with several autoimmune diseases, the major one Ménière s Disease Microscopic Polyangiitis - Mixed connective tissue Disease http://www.thelupuslady.com/

var srl33t_id = '7661'; Site Resources Message Board - NEW!! Email Support Group Autoimmune Newsletter Nutrition Newsletter - NEW!! Health Webrings The Lupus Lady's BLOG - NEW!! Manage Your Care Before Your Diagnosis Look Up Medication Look Up Lab Tests Find a Physician ... Health Magazines Glyconutrients My Journal Demand Better Nutrition Wellness Background FAQ ... Request More Info Mental Health The Stages Of Grief Feel Better Help Others You Have Lupus When A Dedication ... Getting Some Sleep Courage Profiles Stephen W. Hawkings - Christopher Reeves - Michael J. Fox Homemaking Help Chronic Cooking Tips Once A Month Cooking Recommended Reading Books I've Read Immune Disease Autoimmune Glyconutrients Inspirations Womanhood Success - NEW!! Happiness/Joy Life's Purpose Love Persistence ... Favorite Bible Verses In The Works - "Manage Your Care" Kit - Doctor Info Pack - Pamphlets In PDF Form International Lupus Meetup Day Search This Site: AWARDS Privacy Statement The Lupus Lady's Autoimmune Disease Support Site repects your privacy and assures you that any and all information given to this site by e-mail or any other way will be kept confidential and will not be sold or otherwise disclosed to any third parties. Currently onl ine Guests Living With Chronic Illness ~ Thriving in the face of adversity!

56. Antiphospholipid Syndrome The antiphospholipid antibody syndrome is an autoimmune phenomenon. disorder suchas systemic lupus erythematosus or a mixed connective tissue disorder. http://www-admin.med.uiuc.edu/hematology/PtAPS.htm

University of Illinois - Urbana/Champaign Carle Cancer Center Hematology Resource Page Patient Resources Antiphospholipid Antibody Syndrome Home Factor V Leiden Antiphospholipid Syndrome General Clotting Information ... Protein S deficiency The antiphospholipid antibody syndrome, also known as Hughes Syndrome, is a disorder characterized by multiple different antibodies that are associated with both arterial and venous thrombosis (clots). There are three primary classes of antibodies associated with the antiphospholipid antibody syndrome: 1) anticardiolipin antibodies, 2) the lupus anticoagulant and 3) antibodies directed against specific molecules including a molecule known as beta-2-glycoprotein 1. Historically, antiphospholipid antibodies were first noted in patients who had positive tests for syphilis without signs of infection. Subsequently, a clotting disorder was associated with two patients with systemic lupus erythematosus in 1952. In 1957 a link between recurrent pregnancy loss and what is now called the lupus anticoagulant was established. Ultimately, the lupus anticoagulant was further described in 1963 and in 1972 the term lupus anticoagulant was given. In 1983, Dr. Graham Hughes described the association between antiphospholipid antibodies and arterial as well as venous thrombosis. There are two main classifications of the antiphospholipid antibody syndrome. If the patient has an underlying autoimmune disorder, such as systemic lupus erythematosus, the patient is said to have secondary antiphospholipid antibody syndrome. If the patient has no known underlying autoimmune disorder, it is termed primary antiphospholipid antibody syndrome.

57. Arch Dermatol -- Topic Collections : Connective Tissue Diseases connective tissue diseases. Contributing journals to this collection Effects of Mothers autoimmune Disease During Pregnancy on Learning Disabilities http://archderm.ama-assn.org/cgi/collection/connective_tissue_diseases?notjourna

58. Raynaud's Phenomenon existing connective tissue or autoimmune disease; cigarette smoking (in men) Online resources of Cardiovascular Disease. Print this Page http://www.healthsystem.virginia.edu/UVAHealth/adult_cardiac/raynaud.cfm

[ Skip Navigation ] Health System Home For Health Answers Healthcare Professionals ... Advanced Search Health System Search Search for Information People UVa Home Health System News Health System Events (all) Health System Publications ... Making a Gift Topics All About Cancer Blood Disorders Bone Disorders Breast Health Cancer Cardiovascular Disease Dermatology Diabetes Digestive Disorders Endocrinology Environmental Medicine Eye Care Glossary Gynecological Health Infectious Diseases Kidney Disease Men's Health Mental Health Nervous System Disorders Non-Trauma Emergency Oral Health Orthopaedics Otolaryngology Pathology Pediatrics, General Health Prostate Health Radiology Respiratory Disorders Skin Cancer Surgical Care Urology Women's Health UVa Health Topics A to Z FIND A DOCTOR Adult Congenital Heart Disease Cardiac Rehabilitation Cardiovascular Surgery ... WHY CHOOSE UVA Search This Site Raynaud's Phenomenon What is Raynaud's phenomenon? Raynaud's phenomenon or, simply, Raynaud's, is a disorder characterized by decreased blood flow - usually to the fingers, and less frequently to the ears, toes, nipples, knees, or nose. Vascular spasms usually occur as attacks in response to cold exposure or emotional upset. Raynaud's can occur alone or may occur with other diseases. The diseases most frequently associated with Raynaud's are autoimmune or connective tissue diseases, among others, such as the following:

59. Raynaud''s Phenomenon existing connective tissue or autoimmune disease; cigarette smoking (in men) Online resources page of this Web Site. Print this Page Email this Page http://www.healthsystem.virginia.edu/uvahealth/adult_arthritis/raynaud.cfm

[ Skip Navigation ] Health System Home For Health Answers Healthcare Professionals ... Advanced Search Health System Search Search for Information People UVa Home Health System News Health System Events (all) Health System Publications ... Making a Gift Topics All About Cancer Blood Disorders Bone Disorders Breast Health Cancer Cardiovascular Disease Dermatology Diabetes Digestive Disorders Endocrinology Environmental Medicine Eye Care Glossary Gynecological Health Infectious Diseases Kidney Disease Men's Health Mental Health Nervous System Disorders Non-Trauma Emergency Oral Health Orthopaedics Otolaryngology Pathology Pediatrics, General Health Prostate Health Radiology Respiratory Disorders Skin Cancer Surgical Care Urology Women's Health UVa Health Topics A to Z FIND A DOCTOR Arthritis and Rheumatology General Orthopaedic Surgery Joint, Hip and Knee Replacement ... WHY CHOOSE UVA Search This Site Raynaud's Phenomenon What is Raynaud's phenomenon? Raynaud's phenomenon or, simply, Raynaud's, is a disorder characterized by decreased blood flow - usually to the fingers, and less frequently to the ears, toes, nipples, knees, or nose. Vascular spasms usually occur as attacks in response to cold exposure or emotional upset. Raynaud's can occur alone or may occur with other diseases. The diseases most frequently associated with Raynaud's are autoimmune or connective tissue diseases, among others, such as the following:

60. Autoimmunity/Connective Tissue Biology Training Grant At Dartmouth Medical Schoo Arthritis and related connective tissue disorders are among the most common are characterized by a strong autoimmune component, while diseases like http://www.cancer.dartmouth.edu/education/actbtf.shtml

In Affiliation with: Dartmouth Medical School Dartmouth-Hitchcock Medical Center The National Cancer Institute Welcome to Norris Cotton Cancer Center Contact About Directions Media You are: Home Education Quick Links Clinical Services Patient Support Services Oncology Nursing Clinical Trials ... Read the Cancer Center Newsletter Enter your email address to receive periodic updates from the Cancer Center. Email Address Autoimmunity/Connective Tissue Biology Training Grant at Dartmouth Medical School Contact Dr. William Rigby for more information. Many rheumatic diseases, such as rheumatoid arthritis and systemic lupus erythematosus are characterized by a strong autoimmune component, while diseases like scleroderma clearly demonstrate the link between autoimmunity and disordered connective tissue biology. In addition, it is clear that a component of the inflammatory response involves changes in tissue oxygen tension, altered vascularity/endothelial cell function and the perception of pain. Thus, an understanding of the fundamental mechanisms controlling both the immune response and the biochemistry and molecular biology of cellular functions impacts directly on our understanding of connective tissue diseases. The training of excellent young investigators who are knowledgeable in this important area of biomedical research is the central mission of this application. The Autoimmunity/Connective Tissue Biology Program Faculty has documented experience in the training of graduate students and postdoctoral fellows (219 in the last 10 years), with vigorous and competitive research programs (~ $13 million in annual direct costs only counting individual research grants), and have developed a series of courses and seminars that critically address fundamental mechanisms involved the immunology, biochemistry and molecular genetics of connective tissue metabolism. Perhaps most important, this Program Faculty has demonstrated a distinguished training record (100% of our first 11 postdoctoral trainees remain in research, 7/11 as independently funded Assistant Professors) for its pre- and post-doctoral trainees overall as well as in the very short period of NIAMS Training Grant support. The Program Faculty of (15 trainers) has continued to evolve, adding 4 new trainers over the past 4 years.

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