81. Acquired Aplastic Anemia -- Young 136 (7): 534 -- Annals Of Internal Medicine In aplastic anemia, hematopoiesis fails Blood cell counts are extremely low, The pathophysiology of aplastic anemia is now believed to be http://www.annals.org/cgi/content/abstract/136/7/534

Search Annals: Advanced search Home Current Issue Past Issues ... ACP Online Article Table of Contents Full Text of this article PDF of this article (PDFs free after 6 months) Figures/Tables List Services Send comment/rapid response letter Notify a friend about this article Alert me when this article is cited Add to Personal Archive ... ACP Search PubMed Articles in PubMed by Author: Young, N. S. Related Articles in PubMed PubMed Citation PubMed UPDATE Acquired Aplastic Anemia Neal S. Young, MD In aplastic anemia, hematopoiesis fails: Blood cell counts are extremely low, and the bone marrow appears empty. The pathophysiology of aplastic anemia is now believed to be immune-mediated, with active destruction of blood-forming cells by lymphocytes. The aberrant immune response may be triggered by environmental exposures, such as to chemicals and drugs or viral infections and, perhaps, endogenous antigens generated by genetically altered bone marrow cells. In patients with post-hepatitis aplastic anemia, antibodies to the known hepatitis viruses are absent; the unknown infectious agent may be more common in developing countries, where aplastic

82. Aplastic Anemia - Cambridge University Press The first book on aplastic anemia to have such an emphasis on treatment Stem cell defect in aplastic anemia JCW Marsh and NG Testa; 2. http://www.cambridge.org/catalogue/catalogue.asp?isbn=0511036256

83. Aplastic Anemia - Cambridge University Press Stem cell defect in aplastic anemia JCW Marsh and NG Testa; 2. Interrelation between aplastic anemia and paroxysmal nocturnal hemoglobinuria G. Socié, http://www.cambridge.org/uk/catalogue/catalogue.asp?isbn=0511036256

84. Team 061 - Aplastic Anemia Area of Science Medicine and Health. Project Title aplastic anemia. aplastic anemia is a disease that causes an unexplained failure of the bone marrow http://www.challenge.nm.org/abstracts/061.html

85. Aplastic Anemia: BC Cancer Agency Reviewed 26 July 2005 General Information aplastic anemia and MDS International Foundation http://www.bccancer.bc.ca/PPI/RecommendedLinks/CancerRelatedWebsites/AplasticAne

Agency Links: Home Contact Us Legal Privacy ... Cancer Websites Aplastic Anemia Recommended Links Cancer Websites General Cancer Websites Advocacy ... After Cancer Aplastic Anemia Beauty Breast Clinical Trials Colorectal ... Waldenstrom's Macroglobulinemia Cancer Websites - Aplastic Anemia Print Wizard Print this Page Reviewed: 26 July 2005 General Information Aplastic Anemia and MDS International Foundation Print Wizard Print this Page The BC Cancer Agency is a part of the Provincial Health Services Authority If you notice a problem with this page, please report it via the Bug Report Form . Thank you. Unofficial document if printed . Please refer to the following web address for up-to-date information:

86. DFCI/BWH Cancer Center: Aplastic Anemia Treatment Learn about aplastic anemia treatments, prevention, symptoms and risks. http://www.dana-farber.org/center-for-hematologic-oncology/a-anema.asp

Aplastic Anemia Treatment To make an appointment: Make an appointment now Please call or complete our on-line Request an Appointment form About Dana-Farber/Brigham and Women's Cancer Center The dedicated experts in our Center for Hematologic Oncology provide comprehensive, compassionate care for cancer patients and their families. We offer a variety of innovative treatment options for aplastic anemia. Services Offered Evaluation and diagnosis of individuals with aplastic anemia (including second opinions) Development and implementation of a personalized treatment plan Access to new therapies through clinical research protocols Comprehensive bone marrow/stem cell transplantation services Psychosocial evaluation and support Full consultative and therapeutic services Access to complementary therapies through the Leonard P. Zakim Center for Integrated Therapies Coordinated follow-up care From diagnosis to treatment, Dana-Farber/Brigham and Women's Cancer Center provides expert care for hematologic malignancies and cancers of the blood. To make an appointment for diagnosis or treatment, please contact us at , or fill out the on-line form . Your privacy is assured.

87. Secondary Aplastic Anemia Alternative Names. Anemia secondary aplastic; Acquired aplastic anemia. Causes. Secondary aplastic anemia results from injury to stem cells. http://www.lifespan.org/ADAM/English/HIE/000529.htm

Careers at Lifespan Volunteer your time Other ways to give Lifespan's A - Z Health Information Library Injury Disease Nutrition Poison ... Prevention Secondary aplastic anemia Definition Secondary aplastic anemia is a failure of the bone marrow to form enough blood cells. All blood cell types are affected. Alternative Names Anemia - secondary aplastic; Acquired aplastic anemia Causes Secondary aplastic anemia results from injury to stem cells. Normal stem cells divide and differentiate into all blood cell types. Thus, when stem cells are injured, there is a reduction in red blood cells, white blood cells, and platelets. This condition can be caused by chemotherapy, drug therapy to suppress the immune system, radiation therapy, toxins such as benzene or arsenic, drugs, pregnancy, and congenital disorders. When the cause is unknown, it is then referred to as idiopathic aplastic anemia The disease may be acute or chronic and is usually gets worse unless the cause is removed. Bone marrow aspiration Blood types Review Date: 5/6/2003 Reviewed By: Ezra E. W. Cohen, M.D., Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL. Review provided by VeriMed Healthcare Network.

88. Kailee Wells, And I Have Aplastic Anemia (Very Severe Aplastic Anemia). I Need A Hi, I m Kailee Wells, and I have aplastic anemia (Very Severe aplastic anemia). My family and doctors are searching for a bone marrow donor for me because I http://www.kaileegetwells.com/

Dear Friends – As you may know, I was diagnosed with Severe Aplastic Anemia in January of 2002. I had just turned 5 years old. Since then, I have had every possible medical treatment for this disease, including several different rounds of profound immune-suppression. My family, doctors and many other people have continuously searched for a matching bone marrow donor for me because a successful bone marrow transplant is my last chance to get rid of this “stupid Aplastic Anemia” once and for all! My parents, with the help of many, many others, have worked with people all over the world to let everyone know about the need for people to become committed potential bone marrow donors. It’s simple. It’s easy. I just know that if people knew that a finger poke is all that is needed to register your marrow, everyone would join the world marrow registry. And please don’t forget to donate blood and platelets as often as you can. I need transfusions every week, and there are thousands of others just like me who depend on the loving kindness of others to live, until we get rid of our diseases. We urge you to join a marrow registry by contacting your local blood center. If you are already a blood donor, ask to register your marrow the next time you give blood. Let every expectant parent know that they can help by donating their baby's umbilical cord free of charge. Help by organizing a bone marrow donor drive where you live and work. Together, we can save thousands of people like me who continue to search and hope for a match.

89. Kailee Wells, And I Have Aplastic Anemia (Very Severe Aplastic Anemia). I Need A Hi, I m Kailee Wells, and I have aplastic anemia (Very Severe aplastic anemia). My family and doctors are searching for a bone marrow donor for me because I http://www.kaileegetwells.com/update.htm

Kailee Home from the Hospital! Photos from the Hospital I love to get messages from people. Please sign my Guestbook! Children's Hospital of Wisconsin, Kailee's Hospital in Milwaukee Dr. David A. Margolis, Kailee's Doctor at Children's Hospital, Milwaukee, WI Saturday, September 17, 2005 Dear Friends - BIG BIG NEWS HERE! Our suitcases were completely packed and at the front door, when we got word that the China Marrow Donor Program found THE GENETIC MARROW MATCH FOR KAILEE! This, after 3 1/2 years of searching; after searching through almost 10 million people in the world registry with no match, finally the donor we have been praying for walked in to a blood center somewhere in China. Kailee's doctor, Dave Margolis and our search coordinator, Kathy Jadarski, have had several communications with the people at the Red Cross Society in Beijing, the DNA analysis was confirmed, and the donor's consent confirmed just hours before we were to leave for the airport. Now, instead of going to China, we are preparing Kailee (and ourselves) for transplant. Apparently, the donor has just in the last several hours had his physical exam and will begin his preparation soon. It's as though the universe worked together to make this happen. We are truly stunned. Disbelief lingers in the air, but the doctor assures us THIS is what we have been searching for.

90. ATE Responses One of the younger female members of my family has aplastic anemia Ed. Is there any connection that has been documented between aplastic anemia and any http://www.mdausa.org/experts/question.cfm?id=2145

91. LII - Results For "aplastic Anemia" aplastic anemia MDS International Foundation, Inc. The first week in December is National aplastic anemia Awareness Week, and this Web site has http://www.lii.org/advanced?searchtype=subject;query=Aplastic anemia;subsearch=A

92. Congenital Aplastic Anemia Caused By Mutations In The SBDS Gene: A Rare Presenta aplastic anemia was diagnosed at birth for a first child from healthy Key Words aplastic anemia • hematology • genotype • congenital • bone marrow http://pediatrics.aappublications.org/cgi/content/abstract/114/3/e387

QUICK SEARCH: [advanced] Author: Keyword(s): Year: Vol: Page: PEDIATRICS Vol. 114 No. 3 September 2004, pp. e387-e391 (doi:10.1542/peds.2003-0651-F) This Article Full Text Full Text (PDF) P ... Citation Map Services E-mail this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal ... Cited by other online articles PubMed PubMed Citation Articles by Kuijpers, T. W. Articles by Hennekam, R. C. M. Related Collections ELECTRONIC ARTICLE Congenital Aplastic Anemia Caused by Mutations in the SBDS Gene: A Rare Presentation of Shwachman-Diamond Syndrome Clinical Findings. Aplastic anemia was diagnosed at birth for a first child from healthy nonconsanguineous parents. The girl had hypoglycemia, which normalized within 2 months. Cow milk allergy was suspected initially, because of skin lesions and diarrhea, followed by severe growth retardation. Clinical and radiologic symptoms gradually became typical for Shwachman-Diamond syndrome. Two common mutations in the

93. Disease Category Listing (282): Aplastic Anemia CenterWatch Listing of Clinical Research Trials for aplastic anemia. http://www.centerwatch.com/patient/studies/cat282.html

Clinical Trials: Aplastic Anemia New York New York; Columbia-Presbyterian Medical Center Study of standard chemotherapy and radiotherapy before allogeneic stem cell transplantation New York; Columbia-Presbyterian Medical Center Study of transplantation using umbilical cord and placental blood Back to Clinical Trials by Medical Areas Research centers specializing in this illness area Additional resources ... in this illness area This site is run by CenterWatch, a publishing company that focuses on the clinical trials industry. The information provided in this service is designed to help patients find clinical trials that may be of interest to them, and to help patients contact the centers conducting the research. CenterWatch is neither promoting this research nor involved in conducting any of these trials. Trial listing updated: September 14, 2005 at 3:00:29 PM Patient Resources: [ Trial Listing Notification Services Drug Directories About Clinical Research ... Patient Bookstore Professional Resources: [ Research Center Profiles Industry Provider Profiles Industry News Professional Resources ... Professional Bookstore General: [ Search Site Map Your Privacy CW World ... Home This site was developed in association with Illumina Interactive , Boston, MA

94. C-Health : Aplastic Anemia The blood that circulates throughout the body performs a number of critical functions. It delivers oxygen, removes carbon dioxide, http://chealth.canoe.ca/condition_info_details.asp?disease_id=264&rot=4

95. Aplastic Anemia And Myelodysplasia Association Of Canada View Dr. Gupta s Presentation on aplastic anemia (Jan 2005) Myelodysplasia is similar to aplastic anemia in that production of blood cells is decreased; http://www.aamac.ca/

Aplastic Anemia and Myelodysplasia Association of Canada (updated August 11, 2005) NEW: AAMAC/CIHR Doctoral Research Award announced View Dr. Gupta's Presentation on Aplastic Anemia (Jan 2005) View Dr. Well's Presentation on MDS (April 2004) Make a Donation Research you can participate in Understanding Aplastic Anemia and Myelodysplasia Description Causes Treatments How can I help? We also have numerous documents generously supplied by the You can obtain these educational materials and MORE by calling our toll-free line . Also, ask to get on our mailing list. Aquired Aplastic Anemia - Basic Explanations Myelodysplastic Syndromes - Basic Explanations PNH - Basic Explanations Teachers/School Nurses Guide to Bone Marrow Failure Disease The Association Mandate Board of Directors How to Contact Us Other AAMAC Links Alberta Chapter Home Page British Columbia Chapter Home Page Other AA/MDS/PNH Associations AA-MDS-TALK EMail List The Aplastic Anaemia Trust The Myelodysplastic Syndromes Foundation PNH On-Line Support Group Anemia-Related Links Fanconi Canada Anemia Institute for Research and Education Thalassemia Foundation of Canada The Sickle Cell Association of Ontario ... Canadian Celiac Association Blood-Related Links Canadian Blood Services Hema-Quebec Bone Marrow Registry CIMFR - Canadian Inherited Marrow Failure Registry ... Canadian Hemophilia Society Research Links Canadian Leukemia Studies Group What are Aplastic Anemia and Myelodysplasia?

96. FIRSTConsult - Sdfdsf FIRSTConsult, aplastic anemia (Medical Condition File). Published for medical students and primary healthcare providers by Elsevier. http://www.firstconsult.com/?action=view_article&id=1014695&type=101&bref=1

97. Gout And Aplastic Anemia Symptoms-relationship? - Health And Medical Information Doctorproduced health and medical information written for you to make informed decisions about your health concerns. http://www.medicinenet.com/script/main/art.asp?articlekey=18906

98. Acquired Aplastic Anemia Acquired aplastic anemia is a rare disorder caused by profound, almost complete bone marrow failure. Bone marrow is the spongy substance found in the center http://www.bchealthguide.org/kbase/nord/nord83.htm

var hwPrint=1;var hwDocHWID="nord83";var hwDocTitle="Acquired Aplastic Anemia";var hwRank="1";var hwSectionHWID="nord83-Header";var hwSource="en-caQ2_05";var hwDocType="Nord"; National Organization for Rare Disorders, Inc. Acquired Aplastic Anemia Important It is possible that the main title of the report Acquired Aplastic Anemia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms Idiopathic Aplastic Anemia Disorder Subdivisions None General Discussion Resources P.O. Box 613 Annapolis, MD 21404-0613 USA Tel: 4108670242 Fax: 4108670240 Tel: 8007472820 Email: help@aamds.org Internet: http://www.aamds.org Earl J. Goldberg Aplastic Anemia Foundation P.O. Box1324 North Brook, IL 60065 Tel: (847)559-0688 Internet: http://www.ejgaaf.org NIH/National Heart, Lung and Blood Institute 31 Center Drive MSC 2480 Building 31A Rm 4A16 Bethesda, MD 20892-2480 Tel: (301)592-8573 Fax: (301)480-4907 Email: nhlbiinfo@rover.nhlbi.nih.gov Internet: http://www.nhlbi.nih.gov/

99. University Of Chicago Hospitals: Aplastic Anemia Detailed information on aplastic anemia, including cause, symptom, diagnosis, and treatment. http://www.uchospitals.edu/online-library/library.html?content=P00075

100. Aplastic Anemia aplastic anemia. AAMDS-TALK website aafa-ner.org/aa-mds aplastic anemia MDS International Foundation, Inc. PO Box 613 Annapolis, MD 21404-0613 http://www.bmtinfonet.org/resource/index.cfm?Fuseaction=ResourceResults&Category

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