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         Aplastic Anemia:     more books (30)
  1. Fetal Liver Transplantation (Developments in Hematology and Immunology)
  2. Red cell destruction in the anaemias by Henning Letman, 1959

41. Aplastic Anemia
Detailed information on aplastic anemia, including cause, symptom, diagnosis, and treatment.
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      Aplastic Anemia
      What is aplastic anemia?
      Aplastic anemia occurs when the bone marrow produces too few of all types of blood cells: red cells, white cells, and platelets. A reduced number of red blood cells causes the hemoglobin (a type of protein in the red blood cells that carries oxygen to the tissues of the body) to drop. A reduced number of white blood cells causes the patient to be susceptible to infection. A reduced number of platelets can cause the blood not to clot as easily.
      What causes aplastic anemia?

42. Aplastic Anemia
Detailed information on aplastic anemia, including cause, symptom, diagnosis, and treatment.
http://www.healthsystem.virginia.edu/uvahealth/adult_blood/aneaplas.cfm
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        Aplastic Anemia
        What is aplastic anemia?
        Aplastic anemia occurs when the bone marrow produces too few of all three types of blood cells: red blood cells, white blood cells, and platelets. A reduced number of red blood cells causes hemoglobin to drop. A reduced number of white blood cells makes the patient susceptible to infection. And, a reduced number of platelets causes the blood not to clot as easily.
        What causes aplastic anemia?

43. InteliHealth: Aplastic Anemia
InteliHealth Featuring Harvard Medical School s consumer health information. For more than 550 diseases and conditions, learn What Is It?, Symptoms,
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Aplastic Anemia
  • What Is It? Symptoms Diagnosis Expected Duration ... Additional Info
  • What Is It? Aplastic anemia is a rare, potentially fatal disease in which the bone marrow doesn't make enough blood cells. People with aplastic anemia have low levels of all three types of blood cells:

    44. Aplastic Anemia
    aplastic anemia is a serious condition defined as pancytopenia with an empty There are an estimated 24 million cases per year of aplastic anemia,
    http://pedclerk.bsd.uchicago.edu/aplasticanemia.html
    Aplastic Anemia Aplastic anemia is a serious condition defined as pancytopenia with an "empty" bone marrow (hypoplastic or aplastic). The anemia is only one part of the spectrum of sequelae that result from this, and is not as clinically significant as the concomitant neutropenia, lymphopenia and thrombocytopenia. There are an estimated 2-4 million cases per year of aplastic anemia, and the incidence occurs in three peaks: 2-5 years, 20-25 years and 55-60 years. Other causes of pancytopenia include: malignancy (leukemia or other cancer replacing bone marrow), megaloblastic hematopoiesis, viral infection, paroxysmal nocturnal hematuria and myelodysplastic syndrome. Etiology 70% of aplastic anemia cases are idiopathic, but other known causes are:
    • Hereditary:
        Fanconi anemia Dyskeratosis congenital Schwachman-Diamond syndrome Amegakaryocytic thrombocytopenia
      Acquired:
        Direct stem cell destruction Drugs Toxic chemicals Infection (viral, hepatitis) Immune disorders Collagen vascular diseases
      Clinical features
      • Anemia: fatigue and pallor Thrombocytopenia: unexplained or excessive bleeding, easy bruising

    45. Aplastic Anemia
    aplastic anemia is a disorder in which the bone marrow greatly decreases or aplastic anemia Foundation of America. PO Box 613, Annapolis, MD 21404.
    http://www.healthatoz.com/healthatoz/Atoz/ency/aplastic_anemia.jsp

    46. Cancer And Blood Diseases | Other Blood Diseases | Aplastic Anemia
    aplastic anemia is suspected when test results indicate that all three blood In addition to low blood cell counts, aplastic anemia is characterized by
    http://www.ucsfhealth.org/childrens/medical_services/cancer/blood/conditions/apl
    University of California, San Francisco About UCSF Search Welcome Hospitals and Clinics Appointments Billing ... Other Resources Other Blood Diseases Aplastic Anemia Signs and Symptoms
    Diagnosis

    Treatment
    Signs and Symptoms Aplastic anemia is suspected when test results indicate that all three blood cell levels are extremely low, but the cells themselves have a relatively normal appearance. It remains a rare disease, striking only two to six of every 1 million people annually in the United States and Europe. In addition to low blood cell counts, aplastic anemia is characterized by other physical symptoms of anemia such as pale skin and fingernails, rapid pulse, heart murmur and fatigue. Children also may exhibit abnormal bleeding including multiple bruises, nosebleeds, bleeding gums and small hemorrhages under the skin as well as infection, especially fever. However, each child may experience symptoms differently. Other possible symptoms include:
    • Headache Dizziness Nausea Shortness of breath Blood in stool Sinus tenderness Enlarged liver or spleen Oral thrush, which produces white patches on a red, moist, swollen surface anywhere in the mouth

    47. Hemic And Lymphatic Diseases
    Information on aplastic anemia from Johns Hopkins/Sidney Kimmel Center. A small set of FAQs answered by the aplastic anemia MDS Int l Foundation, Inc.
    http://www.mic.ki.se/Diseases/C15.html
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    ABOUT KAROLINSKA INSTITUTET
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    Diseases and Disorders Links pertaining to Hemic and Lymphatic Diseases Alert! Patients and laypersons looking for guidance among the target sources of this collection of links are strongly advised to review the information retrieved with their professional health care provider. Start Page Contents: Afibrinogenemia Anemia Anemia, Aplastic Anemia, Hemolytic ... von Willebrand Disease
    Hemic and Lymphatic Diseases BloodBook .com Human Blood [D O'Neil] - Palomar College (US) Normal Blood - HMDS (UK) Cells of the Blood [clickable map] - University of Leicester (UK) A Demo module Montandon et al. ] from HemoSurf/IMC About Erythrocytes , and Leukocytes - Encyclopedia.com About some Hematological Laboratory Tests - ASCLS An Educational Presentation of Basic Hematology - Puget Sound Blood C.(US) Haem.net [laboratory hematology] HemoSurf , an interactive hematology atlas [Woermann et al.] Morphological Cell Atlas [registration required, no charge] - CellaVision AB Some Blood Chemistry Definitions - Carbon Based Corp.

    48. Aplastic Anemia
    In aplastic anemia, your body stops producing enough new blood cells. A rare and serious condition, aplastic anemia can develop at any age.
    http://www.cnn.com/HEALTH/library/DS/00322.html
    International Edition MEMBER SERVICES The Web CNN.com Home Page World U.S. Weather ... Autos SERVICES Video E-mail Newsletters Your E-mail Alerts RSS ... Contact Us SEARCH Web CNN.com In association with:
    RELATED STORIES Anemia Anemia Anemia Aplastic anemia Iron deficiency anemia Sickle cell anemia ... Vitamin deficiency anemia INFORMATION CENTERS: Pick a category Health Centers Family Health Men's Health Women's Health Children's Health Seniors' Health Working Life Pain Management Condition Centers Immune System Allergy Alzheimer's Arthritis Respiratory System Cancer Endocrine System Digestive System Heart and Blood Infectious Disease Mental Health Note: All links within content go to MayoClinic.com Diseases and Conditions Aplastic anemia From MayoClinic.com
    Special to CNN.com
    Overview In aplastic anemia, your body stops producing enough new blood cells. This means you're fatigued and at higher risk of infections and uncontrolled bleeding. A rare and serious condition, aplastic anemia can develop at any age. A variety of treatments is available. Once considered nearly always fatal, aplastic anemia has a much better prognosis today, thanks to advances in treatment. Signs and symptoms Signs and symptoms of aplastic anemia are caused by a shortage of one or more types of blood cells. Signs and symptoms may include:

    49. Aplastic Anemia
    aplastic anemia Foundation of America Fighting aplastic anemia, Richie has Severe aplastic anemia - This page chronicles Richie s struggle with Severe
    http://www.ability.org.uk/Aplastic_Anemia.html
    Our Aims Services Stats ... Z Aplastic Anemia Aplastic Anemia - Etiology, incidence, diagnosis, treatment. Aplastic Anemia - Links to treatment, prevention, diagnosis, email groups, support groups, and personal stories. Aplastic Anemia Foundation of America - Fighting Aplastic Anemia, Myelodysplastic Syndromes, and other bone marrow failure. MEdIC - Aplastic Anemia Answer Book - Patient information. Richie has Severe Aplastic Anemia - This page chronicles Richie's struggle with Severe Aplastic Anemia. It is an excellent source of information on Aplastic Anemia, Hematology, Bone Marrow, Transplants, and Immunosuppression Therapy. Lots of links for support groups and additional info. Webmaster . Site Design by Ability "see the ability, not the disability" Acknowledgments

    50. Information About Aplastic Anemia
    This page contains information about aplastic anemia.
    http://www.mamashealth.com/blood/aplastic.asp

    Mamashealth.com Home
    Blood Diseases Agnogenic Metaplasia
    Amyloidosis

    Aplastic Anemia

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    What is Aplastic Anemia?
    Aplastic anemia is a rare but extremely serious disorder that results from the unexplained failure of the bone marrow to produce enough blood cells. Aplastic anemia is not contagious. It can affect anyone at any age. Symptoms of Aplastic Anemia? Some common symptoms are:
    • unexplained infections unexpected bleeding fatigue
    What Causes Aplastic Anemia? Aplastic anemia has been clearly linked to radiation, environmental toxins, insecticides, and drugs. Benzene-based compounds, airplane glue, and drugs such as chloramphenicol have been linked to aplastic anemia. In some individuals, aplastic anemia is believed to be caused by a virus. How is Aplastic Anemia Diagnosed? If your doctor believes you may have aplastic anemia, he will order blood and bone marrow tests. The blood is tested for very low levels of all three blood cells. The bone marrow will be tested to determine the levels of cells that are responsible for producing blood cells.
    Can Aplastic Anemia be treated?

    51. Aplastic Anemia - Wikipedia, The Free Encyclopedia
    aplastic anemia is a condition where the bone marrow does not produce enough, Treating aplastic anemia involves suppression of the immune system,
    http://en.wikipedia.org/wiki/Aplastic_anemia
    Aplastic anemia
    From Wikipedia, the free encyclopedia.
    Aplastic anemia is a condition where the bone marrow does not produce enough, or any, new cells to replenish the blood cells. One known cause is an autoimmune disorder , where the white blood cells attack the bone marrow. In many cases, the etiology is impossible to determine, but aplastic anemia is sometimes associated with exposure to substances such as benzene or to the use of certain drugs, including chloramphenicol and phenylbutazone The term 'aplastic' refers to the inability of the marrow to function properly. Anemia is the condition of having fewer blood cells than normal, or fewer than needed to function properly. Typically, anemia refers to low red blood cell counts, but aplastic anemia patients have lower counts on all three blood cell types: red blood cells white blood cells , and platelets
    Contents
    edit
    Signs and symptoms
    edit
    Diagnosis
    The diagnosis can only be made on bone marrow biopsy . Before this procedure is undertaken, a patient will generally have had other

    52. Introduction: Aplastic Anemia - WrongDiagnosis.com
    Introduction to aplastic anemia as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.
    http://www.wrongdiagnosis.com/a/aplastic_anemia/intro.htm
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    Introduction: Aplastic anemia
    Aplastic anemia: Anemia from bone marrow not producing enough red blood cells. Researching symptoms of Aplastic anemia: Further information about the symptoms of Aplastic anemia is available including a list of symptoms of Aplastic anemia , or alternatively return to research other symptoms in the symptom center Statistics and Aplastic anemia: Various sources and calculations are available in statistics about Aplastic anemia , and you can also research other medical statistics in our statistics center Contents for Aplastic anemia: Last revision: June 12, 2003

    53. Aplastic Anemia
    CHC Wausau Hospital s Medical Library and Patient Education Center provides research services and healthcare information to physicians,
    http://www.chclibrary.org/micromed/00038280.html

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    Aplastic anemia
    Definition
    Aplastic anemia is a disorder in which the bone marrow greatly decreases or stops production of blood cells. Description
    The bone marrow (soft tissue which is located within the hard outer shell of the bones) is responsible for the production of all the types of blood cells. The mature forms of these cells include red blood cells, which carry oxygen throughout the body; white blood cells, which fight infection; and platelets, which are involved in clotting. In aplastic anemia, the basic structure of the marrow becomes abnormal, and those cells responsible for generating blood cells (hematopoietic cells) are greatly decreased in number or absent. These hematopoietic cells are replaced by large quantities of fat. Yearly, aplastic anemia strikes about 5-10 people in every one million. Although aplastic anemia strikes both males and females of all ages, there are two age groups that have an increased risk. Both young adults (between 15-30 years of age) and the elderly (over the age of 60) have higher rates of aplastic anemia than the general population. While the disorder occurs worldwide, young adults in Asia have a higher disease rate than do populations in North America and Europe.
    Aplastic anemia falls into three basic categories, based on the origin of its cause: idiopathic, acquired, and hereditary.

    54. THE MERCK MANUAL, Sec. 11, Ch. 127, Anemias
    The term aplastic anemia commonly implies a panhypoplasia of the marrow with Although both disorders are uncommon, aplastic anemia is more common.
    http://www.merck.com/pubs/mmanual/section11/chapter127/127c.htm
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    This Publication Is Searchable The Merck Manual of Diagnosis and Therapy Section 11. Hematology And Oncology Chapter 127. Anemias Topics [General] Anemias Caused By Blood Loss Anemias Caused By Deficient Erythropoiesis Anemias Caused By Excessive Hemolysis
    Anemias Caused By Deficient Erythropoiesis
    MICROCYTIC ANEMIAS
    Deficient or defective heme or globin synthesis produces a microcytic RBC population. However, early changes may be minimal. Differential diagnosis (see Table 127-4 ) includes Fe-deficiency, Fe-transport-deficiency, and Fe-utilization anemias, anemia of chronic disease, and the thalassemias (see Anemias Caused by Defective Hemoglobin Synthesis, below). The term microcytic anemia has replaced hypochromic-microcytic anemia because the degree of hypochromia varies.
    Disturbances in Iron Metabolism
    Fe is distributed in active metabolic and storage pools. Total body Fe is about 3.5 g in healthy adult men and 2.5 g in women; the difference relates to body size and the common absence of a significant storage pool in women. The approximate content in the active pool of an average man is Hb, 2100 mg; myoglobin, 200 mg; tissue (heme and nonheme) enzymes, 150 mg; and transport-Fe compartment, 3 mg. Fe is stored in tissue cells as ferritin (700 mg) and hemosiderin (300 mg). Fe absorption: The average American diet, which contains 6 mg of Fe/kcal of food, is adequate for Fe homeostasis. However, significant variation in bioavailability of dietary Fe markedly alters absorption. Fe absorption is best when food contains heme Fe (meat). Various other food items (eg, vegetable fiber phytates and polyphenols; tea tannates, including phosphoproteins; bran) reduce nonheme Fe absorption. Thus, many food-food interactions reduce bioavailability. Ascorbic acid is the only common food element known to increase nonheme Fe bioavailability.

    55. THE MERCK MANUAL--SECOND HOME EDITION, Anemia Of Chronic Disease In Ch. 172, Ane
    The most common cause of aplastic anemia may be an autoimmune disorder, Stem cell or bone marrow transplantation can cure aplastic anemia in younger and
    http://www.merck.com/mmhe/sec14/ch172/ch172e.html
    var externalLinkWarning = "The link you have selected will take you to a site outside Merck and The Merck Manuals.*n*nThe Merck Manuals do not review or control the content of any non-Merck site. The Merck Manuals do not endorse and are not responsible for the accuracy, content, practices, or standards of any non-Merck sources."; Search The Second Home Edition , Online Version Search Index A B C D ... Z Sections Accidents and Injuries Blood Disorders Bone, Joint, and Muscle Disorders Brain, Spinal Cord, and Nerve Disorders ... Women's Health Issues Resources Anatomical Drawings Multimedia Pronunciations Weights and Measures ... , Online Version Section Blood Disorders Chapter Anemia Topics Introduction Anemia From Excessive Bleeding Anemia of Chronic Disease Autoimmune Hemolytic Anemia Hemoglobin C, S-C, and E Diseases Iron Deficiency Anemia Sickle Cell Disease ... Vitamin Deficiency Anemia Anemia of Chronic Disease Buy The Book Print This Topic Email This Topic Pronunciations aphasia aplastic anemia chloramphenicol corticosteroid ... thrombocytopenia In anemia of chronic disease, some chronic disorder slows the production of red blood cells, the result of production of proteins called cytokines that interfere with the production of red blood cells. Chronic disease often leads to anemia, especially in older adults. Conditions such as infections, inflammation, and cancer particularly suppress production of red blood cells in the bone marrow. Since the suppression is usually not severe, anemia develops slowly and is evident only after time. Because the bone marrow is unable to use stored iron in the developing red blood cells, this type of anemia is often called iron-reutilization anemia.

    56. Aplastic Anemia
    aplastic anemia is a rare condition in which the bone marrow is unable to produce blood cells normally.
    http://my.webmd.com/hw/health_guide_atoz/sta123289.asp
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    Who We Are About WebMD Site Map You are in Medical Library Our Content Sources Ask A Question Clinical Trials Health Guide A-Z Health Topics Symptoms Medical Tests Medications ... Support Organizations Aplastic anemia Aplastic anemia is a rare condition in which the bone marrow is unable to produce blood cells normally. The production of just some blood cells (such as red blood cells only) may be affected, or the production of all types of blood cells may be decreased. Symptoms of aplastic anemia usually develop gradually and include:
    • Fatigue, weakness, or lack of energy. Headaches or breathing problems that occur after exercise. Infections that keep returning or are more severe than usual. Frequent nosebleeds or bleeding under the skin.
    Causes of aplastic anemia can include:
    • Exposure to poisonous (toxic) chemicals.

    57. Acquired Aplastic Anemia
    Acquired aplastic anemia is a rare disorder caused by profound, almost complete bone marrow failure.
    http://my.webmd.com/hw/anemia/nord83.asp
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    Who We Are About WebMD Site Map Health Topics Symptoms ... For a Complete Report Acquired Aplastic Anemia Important It is possible that the main title of the report Acquired Aplastic Anemia is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. Synonyms
    • Idiopathic Aplastic Anemia
    Disorder Subdivisions
    • None
    General Discussion Resources P.O. Box 613 Annapolis, MD 21404-0613 USA Tel: 4108670242 Fax: 4108670240 Tel: 8007472820 Email: help@aamds.org Internet: http://www.aamds.org Earl J. Goldberg Aplastic Anemia Foundation P.O. Box1324 North Brook, IL 60065 Tel: (847)559-0688 Internet: http://www.ejgaaf.org NIH/National Heart, Lung and Blood Institute 31 Center Drive MSC 2480 Building 31A Rm 4A16 Bethesda, MD 20892-2480

    58. Dr. Koop - Idiopathic Aplastic Anemia
    Idiopathic aplastic anemia is a failure of the bone marrow to properly form all types of blood cells.
    http://www.drkoop.com/ency/93/000554.html
    Home Health Reference Idiopathic aplastic anemia Jul 29, 2005 Search: Dr.Koop MEDLINE Diseases Symptoms Procedures Natural Medicine ... Drug Library
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    Idiopathic aplastic anemia
    Definition: Idiopathic aplastic anemia is a failure of the bone marrow to properly form all types of blood cells.
    Alternative Names: Anemia - idiopathic aplastic
    Causes, incidence, and risk factors: Idiopathic aplastic anemia is a condition that results from injury to the stem cell, a cell that gives rise to other cell types after it divides. Consequently, there is a reduction in all cell types red blood cells, white blood cells and platelets with this type of anemia , which is called pancytopenia. The cause of idiopathic aplastic anemia is unknown, but is thought to be an autoimmune process (the body reacting against its own cells). Causes of other types of aplastic anemia may be chemotherapy radiation therapy toxins , drugs, pregnancy, congenital disorder, or systemic lupus erythematosus
    Symptoms arise as the consequence of bone marrow failure. Llow red blood cell count (anemia) leads to fatigue and weakness. Low white blood cell count (leukopenia) causes an increased risk of infection. Low platelet count (

    59. Aplastic Anemia Definition - Medical Dictionary Definitions Of Popular Medical T
    Online Medical Dictionary and glossary with medical definitions.
    http://www.medterms.com/script/main/art.asp?articlekey=2308

    60. Aplastic Anemia: Definition And Much More From Answers.com
    aplastic anemia n. A form of anemia in which the capacity of the bone marrow to generate red blood cells is defective.
    http://www.answers.com/topic/aplastic-anemia
    showHide_TellMeAbout2('false'); Business Entertainment Games Health ... More... On this page: Dictionary Medical WordNet Wikipedia Mentioned In Or search: - The Web - Images - News - Blogs - Shopping aplastic anemia Dictionary aplastic anemia
    n. A form of anemia in which the capacity of the bone marrow to generate red blood cells is defective. This anemia may be caused by bone marrow disease or exposure to toxic agents, such as radiation, chemicals, or drugs. Also called pancytopenia
    Medical
    aplastic anemia
    n. A form of anemia in which the capacity of the bone marrow to generate red blood cells is defective, caused by bone marrow disease or exposure to toxic agents, such as radiation, chemicals, or drugs. WordNet Note: click on a word meaning below to see its connections and related words. The noun aplastic anaemia has one meaning: Meaning #1 anemia characterized by pancytopenia resulting from failure of the bone marrow; can be caused by neoplasm or by toxic exposure
    Synonym: aplastic anemia
    Wikipedia
    aplastic anemia Aplastic anemia is a condition where the bone marrow does not produce enough, or any, new

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