21. EMedicine - Amyotrophic Lateral Sclerosis : Article Excerpt By: Fernando Dangond Synonyms, Key Words, and Related Terms ALS, Lou Gehrig disease, Lou Gehrig sdisease, Charcot disease, Charcot s disease, motor neuron disease http://www.emedicine.com/neuro/byname/amyotrophic-lateral-sclerosis.htm

(advertisement) Excerpt from Amyotrophic Lateral Sclerosis Synonyms, Key Words, and Related Terms: ALS, Lou Gehrig disease, Lou Gehrig's disease, Charcot disease, Charcot's disease, motor neuron disease Please click here to view the full topic text: Amyotrophic Lateral Sclerosis Background: Amyotrophic lateral sclerosis (ALS) is a devastating disorder of the anterior horn cells of the spinal cord and the motor cranial nuclei that leads to progressive muscle weakness and atrophy. Although major recent advances have shed light on its etiology, the key mechanisms in both familial and sporadic ALS remain unknown. No cure is known. This article reviews the major breakthroughs in ALS research, the clinical aspects of the disease, and current therapeutic options. An outline of new and promising technology and its application to the understanding of ALS is presented. Pathophysiology: ALS primarily involves anterior horn cells in the spinal cord and cranial motor nerves. Patients may have weakness of bulbar muscles or of single or multiple limb muscle groups. Presentation is not always bilateral or symmetrical. A predominantly bulbar form usually leads to more rapid deterioration and death. Limb weakness is predominantly distal. Weakness and atrophy of the intrinsic hand muscles are prominent. Weakness progresses to involve the forearms and shoulder girdle muscles and the lower extremities. Involvement of both upper and lower motor neurons is characteristic. Patients develop variable hyperreflexia, clonus, spasticity, extensor plantar responses, and limb or tongue fasciculations. Wallerian degeneration of corticospinal and corticobulbar tracts may be demonstrated by MRI (high-intensity T2 lesions in frontal lobes) or in postmortem examination. Extraocular muscles and bladder and anal sphincter muscles typically are spared.

22. New York Yankees News A long story short, he was diagnosed with ALS, Lou Gehrig s disease. referred to as Lou Gehrig s disease, is a neurodegenerative disease that attacks http://newyork.yankees.mlb.com/NASApp/mlb/nyy/news/nyy_news.jsp?ymd=20030620&con

23. Encyclopedia Table Of Contents neuromuscular Disorders (eg, ALS/Lou Gehrig s disease) neuroOncology neuro-Ophthalmology Pediatric Ophthalmology Retina diseases. Genetics http://www.pennhealth.com/ency/

24. Neurology Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig s disease). Aneurysm, Cerebral Myasthenia Gravis. neuroophthalmologic Disorders. Parkinson s disease http://www.westfloridahospital.com/CustomPage.asp?guidCustomContentID={86ADF80D-

25. Lou Gehrig Disease ALS/Lou Gehrig s disease Nutritional causes, therapies, remedies . also knownas Lou Gehrig s disease, is a progressive neuro degenerative http://www.jogeorgeclinic.co.uk/1041-lougehrigdisease-10138.html

Top Health Sites - Results for lou gehrig disease ... Amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease, is a progressive neuromuscular disease that weakens and eventually destroys motor neurons (components of the nervous system ... Lou Gehrig :: The Official Web Site Lou Gehrig Disease

26. Amyotrophic Lateral Sclerosis - Lou Gehrig Disease - Information Page With HONse Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig s disease) Diagnosis, Symptoms, neurobiology of disease Journal Sample 1, www.neuro.wustl.edu http://www.hon.ch/HONselect/RareDiseases/EN/C10.228.854.139.html

InitBulle("navy","#F8F8F8","#000066",1); HONcode sites All Web sites HONselect News ... Images HONselect Search English French German Spanish Portuguese the word the part of word in MeSH term in MeSH term and description Information on "Amyotrophic Lateral Sclerosis": Medical hierarchy and definition Research Articles Web resources Medical Images Medical News Medical Conferences Clinical Trials Hierarchy English French German Spanish Portuguese Amyotrophic Lateral Sclerosis Definition: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD . Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION , hyperreflexia, DYSARTHRIA , dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) Synonym(s): Lou Gehrig Disease / Motor Neuron Disease, Amyotrophic Lateral Sclerosis / ALS (Amyotrophic Lateral Sclerosis) / Amyotrophic Lateral Sclerosis With Dementia /

27. Neuroscience Center: Physician's Directory ALS Lou Gehrig s disease Muscle Disorders Muscular Dystrophy Myasthenia Gravisneurology - Adult Email allozim@neuro.wustl.edu. Mailing Address http://www.wuphysicians.wustl.edu/physician2.asp?PhysNum=691

28. Neurological Diseases And Disorders (aka ALS, Lou Gehrig s disease). Anencephaly See Cephalic Disorders. AphasiaLinks to Aphasia Resources. Arachnoid Defects. Arachnoiditis http://home.earthlink.net/~electrikmonk/Neuro/inDis.htm

29. Amyotrophic Lateral Sclerosis - Neurological Diseases And Disorders Amyotrophic Lateral Sclerosis Neurological diseases and Disorders Discussion related to Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig s disease). http://home.earthlink.net/~electrikmonk/Neuro/inDisALS.htm

30. ALS Association - Bay Area Chapter Parkinson s, amyotrophic lateral sclerosis (ALS Lou Gehrig s disease),Multiple Sclerosis (MS), or other neuro-degenerative diseases. http://www.alsabayarea.org/press_releases/pr_09_01_04_natl.php

Event Wrap-Up Check out photos from recent ALS Association Bay Area events. What's New ALSA Science Director on New Webcast on September 8 September 1, 2004 -The following news release announces a special Webcast to air Sept. 8 on the involvement of biotechnology and pharmaceutical companies in the quest to find answers to ALS and other neurodegenerative diseases. New Webcast Series Reveals Potential for Neurodegenerative Disease Market Benefits to Patients, Biotech Firms, Pharmaceutical Firms Palo Alto, CA September 1, 2004 (PRIMEZONE) Today, 7 million persons one out of every 40 in the U.S. are afflicted with Alzheimer's, Parkinson's, amyotrophic lateral sclerosis (ALS - Lou Gehrig's disease), Multiple Sclerosis (MS), or other neuro-degenerative diseases. It could take 10 or 20 years, or more to find cures for these horrible illnesses. However, there may be a much shorter path to cures that benefit patients and open a multibillion dollar marketplace for innovative biotech and pharmaceutical companies. The potential is described in a new Webcast series, produced by Killen & Associates. The series is titled "The Neurodegenerative Disease Market:

31. Glyconutritionals ~ Glyconutrients ~ Miracle Sugars ~ Essential ALS Lou Gehrig s disease Angina Anxiety Arthritis neuro-Axonal Dystrophy.Obesity OCD - Obsessive Compulsive Disorder Osteoarthritis Oral Thrush http://parentingdecisions.com/our/glyco.htm

32. Weill Cornell Department Of Neurology And Neuroscience principally Alzheimer s disease, amyotrophic lateral sclerosis (ALS, LouGehrig s disease), Huntington s disease, Parkinson s disease and progressive http://www.med.cornell.edu/neuro/research/neurodegenerative.html

Advanced Search Neurodegenerative Disorders Laboratory INTRODUCTION The focus of the Neurodegeneration Laboratory is to determine the mechanisms of cell death and cell dysfunction which underlie a number of different disorders of the brain. These include both dementing illnesses and movement disorders, principally Alzheimer's disease, amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), Huntington's disease, Parkinson's disease and progressive supranuclear palsy (PSP), which are characterized by progressive neuronal degeneration in specific brain regions. In particular, we are interested in the roles that oxidative stress and abnormal energy metabolism in the brain play in all of these disorders, and in turn how these parameters are influenced by genetic mutations and predisposition, as well as extrinsic factors. By characterizing the events leading to neuronal loss in these disorders, the ultimate aim of these studies is to develop therapeutic strategies to both prevent disease onset and halt symptom progression. EXPERIMENTAL APPROACHES The experimental approaches used in the laboratory explore how cerebral function is altered in both affected human tissue and in transgenic mouse models of different neurodegenerative disorders. Techniques employed include HPLC to measure alterations in neurochemical levels ex vivo, notably energy metabolites and markers of free radical-mediated oxidative damage in cells; biochemical assays of metabolic enzyme activities; cell culture and cybrid approaches to measure mitochondrial and cell function in vitro; In vivo autoradiography to measure cerebral glucose metabolism; in vitro autoradiographic techniques to investigate neurotransmitter alterations; excitotoxic and mitochondrial toxin models of cell- and region-specific degeneration.

33. Neuro Final 2002 BL A615 Neural bases of behavior Final examination - Fall, 2002, - Prof. familial version of amyotropic lateral sclerosis (ALS, Lou Gehrig s disease)? http://starklab.slu.edu/neuro/Final2002.htm

BL A-415 Nerve cell mechanisms in behavior BL A-615 Neural bases of behavior Final examination - Fall, 2002, - Prof. Stark Keep "essays" brief. Pay close attention to exact information asked. 1. To what system does the globus pallidus belong? (1 point) 2. When Sperry rotated the eye of the adult frog 180o, what was the result? (1 point) 3. What is the source of cells that will become the autonomic ganglia? (1 point) 4. What happened after a bad batch of drugs contaminated with a substance called MPTP hit the streets? (1 point) 6. What was lesioned and what was the effect in the Kluver-Bucy syndrome? (2 points) 7. Discussing the amygdala, your text states, "...associative learning process itself is probably a Hebbian-like mechanism..." What do they mean "Hebbian?" (1 point) 8. How can your muscle contractions be steady when they are mediated by a train of action potentials in the spinal motor neuron? (1 point) 9. A patient with the corpus callosum severed feels (but cannot see) an object with the left hand. Does (s)he know what the object is and can (s)he name it? (2 points) 10. What is fluoxetine (Prozac) used to treat and how does it act pharmacologically? (2 points)

34. Neuro Final Answers 2002 a neural circuit that reverberates because of excitatory connections the familial version of amyotropic lateral sclerosis (ALS, Lou Gehrig s disease)? http://starklab.slu.edu/neuro/FinalAnswers2002.htm

BL A-415 Nerve cell mechanisms in behavior BL A-615 Neural bases of behavior Final examination - Fall, 2002, - Prof. Stark Keep "essays" brief. Pay close attention to exact information asked. 1. To what system does the globus pallidus belong? (1 point) extrapyramidal motor system 2. When Sperry rotated the eye of the adult frog 180o, what was the result? (1 point) the retina tectum connections were re-established, but visual behavior was reversed 3. What is the source of cells that will become the autonomic ganglia? (1 point) neural crest (ultimately ectoderm) 4. What happened after a bad batch of drugs contaminated with a substance called MPTP hit the streets? (1 point) induced Parkinson's called anterograde amnesia, could not learn anything after the surgery 6. What was lesioned and what was the effect in the Kluver-Bucy syndrome? (2 points) amygdala, lost fear, became docile, hypersexual 7. Discussing the amygdala, your text states, "...associative learning process itself is probably a Hebbian-like mechanism..." What do they mean "Hebbian?" (1 point) a neural circuit that reverberates because of excitatory connections 8. How can your muscle contractions be steady when they are mediated by a train of action potentials in the spinal motor neuron? (1 point)

35. Neuroblastoma Neurological diseases, Research Young Scholars ALS/Lou Gehrig s disease Diabetes Nerve Trauma Spinal Cord Injury Muscular Dystrophy http://www.med.umich.edu/pfund/neuro.htm

PFUND HOME Neurological Diseases Research Young Scholars Summer Program Events ... UMHS HOME Childhood Cancer NEUROBLASTOMA CANCER (NBL) Neuroblastoma is a childhood tumor of the nervous system. If diagnosed over the age of 1 year, patients have a less than 10 % chance of surviving beyond age 5. The spread of neuroblastoma to other parts of the body (metastasis) is the leading cause of death in this disease. Neuroblastoma often metastasizes to bone, which leads to bone destruction, severe pain and fractures. PFUND Inestigators are dedicated to fighting this devastating cancer. The investigation of how neuronal cells survive and can be made to die compliments the neurodegeneration projects well, and has led to remarkable insights into neuron biology. PFUND Investigators are focusing on two areas of neuroblastoma biology: 1) factors that stop tumor growth and 2) factors that prevent metastasis. Tumor cell interactions with their environment provide important insight into how cells move and survive, and may reveal ways to kill these malignant cells. By inestigating these cellular functions, PFUND Investigators hope to identify new ways of treating neuroblastoma cancer. Specifically, the effects of insulin-like growth factor-I (IGF-I) on neuroblastoma cells are under investigation. We have shown that IGF-I allows tumor cells to live, even in the presence of toxic substances. This may underlie the resistance of the tumors to cancer therapy. Gold motility assay; measures cellular mobility in response to growth factors and chemotherapy agents.

36. SupportPath.com: Amyotropic Lateral Sclerosis Also called ALS, Lou Gehrig s disease, wasting palsy Websitehttp//neuromancer.mgh.harvard.edu/cgi-bin/forumdisplay.cgi?action=topics forum= http://www.supportpath.com/sl_a/amyotropic_lateral_sclerosis.htm

Amyotropic Lateral Sclerosis Also called: ALS, Lou Gehrig's Disease, wasting palsy Other topics of interest on SupportPath.com: Caregivers disABILITIES About Us Add-A-Link ... here Online Communities / Message Boards... Braintalk Communities: ALS Website: Description: A part of the BrainTalk Communities website. Registration is required to post to this message board. Date Added: 06/06/2002 Online Chats... None Listed Usenet Groups... Note: Your browser must be properly configured to access Usenet groups from this site. sci.med.diseases.als Website: news:sci.med.diseases.als Description: Usenet group. Date Added: 06/15/2002 Mailing Lists... None Listed National / International Organizations... The ALS Association (ALSA) - mission is to "discover the cause and cure for amyotrophic lateral sclerosis (Lou Gehrig's disease) through dedicated research while providing patient support, information/education for health care professionals and the general public, and advocacy for ALS research and health care concerns." ALS Society of Canada's Homepage Note: Groups are listed alphabetically by U.S. state and then country.

37. Transcript 122802 terryw Kennedy s disease is a rare, progressive neuromuscular disease terryw The symptoms are similar to ALS/Lou Gehrig s disease but are http://www.kennedysdisease.org/122802transcript.html

Kennedy's Disease Chat Transcript Topics: Topic: Open Forum Host: Terry Waite Chat Participants: terryw yves billeric butch stompy speedy john BEGIN CHAT terryw hello yves yves Hello...Terry..how are you terryw I am good. How are you? yves I am a bit tired today..heart problem...irregular rhythm terryw Sorry to hear that Yves yves But I am better this afteroom..in France terryw I must come to France some day. billeric billeric terryw Hello Bill billeric Morning Terry. In case I disappear about nine Terry it's cause a repairman is knocking at the door. Solar hot water heater on the fritz. terryw OK bill terryw terryw terryw Bill, How have you been? billeric Not too bad Terry. I can notice a few things not quite so good. Overall I won't complain. How about you? terryw In winter I always feel as if I am weaker. terryw I love the warm summer. billeric Cold weather just is bad for my hands. Can't do buttons or anything that takes coordination yves Its strange...in France the weather is hot....no cold..no snow...all flower are in bloom

38. University Of Kentucky Department Of Neurology http//www.medtronic.com/neuro/pain/neuropathy/ Medtronic’s site on Painfulneuropathy This Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig s disease) http://www.mc.uky.edu/neurology/support.asp

Medicine Home For Patients News College of Medicine Quick Links Campus Directory Employment Alumni Association Basic Science Departments Clinical Departments Centers Medical Education Integrated Biomedical Sciences Doctoral Programs MD/PhD Program Continuing Medical Education Faculty Resources Postdoctoral Resource Office General Clinical Research Center UK Clinical Research Organization Medical Professions Placement Service UK Health Services Links: About the Department For Patients For Students For Applicants ... Home Neuromuscular Disorders Support Group Information Amyotrophic Lateral Sclerosis Spinal Muscular Atrophy Charcot-Marie Tooth Dejerine-Sottas ... Post Polio Syndrome Neuropathy Links Compiled by Sharman Hammers, PharmD. candidate Spine-Health’s website: All about Neuropathy and Back Pain - Has an introduction section which includes “Types of Pain” and “Anatomy of Nerve Pain”. Other sections include: Common Causes, Conservative Care, Surgery, Diagnostics, and Anatomy. Canadian Neuropathy Association Focuses on patient knowledge of neuropathy. Has a Forum section where patients can read or post questions and discussion topics. Patient Resources section has a list of other helpful websites.

39. Brief Records For I\&R, Health 46032 Provides information and referral regarding ALS/Lou Gehrig s disease . Information Link (800) 4214555; neuro Information Link (877) 774-7125. http://www.imcpl.org/cgi-bin/irnget.pl?I&R, health

40. StevieGuitar.com :: Index concerts to raise awareness of neuromuscular and Environmental disease with The resulting from his recent diagnosiswith ALS - Lou Gehrig s disease, http://www.stevieguitar.com/events.php

aloha! news events biography ... links View Sun Nov 30, 2003 Steve Sparks’ NORTH WOODS REVUE Steve Sparks’ NORTH WOODS REVUE A Benefit Raising Awareness of Neuromuscular Disease PANIDA THEATER – SANDPOINT, IDAHO SUNDAY, NOVEMBER 30TH One O’Clock to Four O’Clock P.M. FEATURING: With Special Guests: “Choo-Choo” CHARLIE WILLIAMS (from Baltimore, Maryland) and The Extraordinary Guitar Duo: Also Performing: DAVID GUNTER, CHARLEY PACKARD, TOM NEWBILL, “Neighbor” JOHN KELLY, RAY ALLEN, SCOTT REID, And Other Special Guests Plus Comedy By RICK REED STAGE MANAGEMENT BY: RICK STEINER OF SANDPOINT MUSIC Tummy-Warming Refreshments By IVANO’S TEN DOLLAR DONATION A SILENT PARTNER PRODUCTION NOTES ON NORTH WOODS REVUE BENEFIT: Former Sandpoint resident Steve Sparks has returned to North Idaho to convalesce two years into a diagnosis of Lou Gehrig’s Disease (ALS - www.alsa.org ) from George Washington University Medical Center in Washington, DC. Area musicians are gathering in celebration of friendship and live music at The Panida Theater (www.panida.org) in Sandpoint, Idaho ( www.sandpoint.com

A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

Page 2     21-40 of 101    Back | 1  | 2  | 3  | 4  | 5  | 6  | Next 20