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         Albinism Genetics:     more detail
  1. Albinism: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Melissa Knopper, 2005
  2. Griscelli syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Sonya Kunkle, 2005
  3. Hermansky-Pudlak syndrome: An entry from Thomson Gale's <i>Gale Encyclopedia of Genetic Disorders, 2nd ed.</i> by Suzanne, MS, CGC Carter, 2005

81. GENETICS OF THE RINGNECK DOVE, Streptopelia Risoria.
Genetic diagraming can follow the same style given for albino and ivorycharacters (ADAN SepOct, Nov-Dec 84). Again you may wish to shorten the pi gene
http://www.ringneckdove.com/Wilmer's WebPage/GENETICS_OF_RINGNECKS.htm
D ove color genotypes phenotypes Origins of ringnecks Stubby dwarf ringnecks ... Return to Wilmer's Main Page GENETICS OF THE RINGNECK DOVE, Streptopelia risoria
by
Wilmer J. Miller
Adapted from ADAN May-Jun 1. Overview A standard of reference is important. I choose to use the wild type = standard type = "normal" which is dark color. This the color found in S. semitorquata, or S. decaocto, or S. roseogrisea , the ancestor of our domestic ringneck. Dark collared doves have a deep red eye, if they are kept outdoors subject to the solar radiation, or even if they are kept indoors and subjected to ultra violet light. Eyes of blond doves are also red, barely a shade lighter? Indoors the eye is a bit lighter red. Plumage of the dark dove may be described as dark gray, Evidently, no one has investigated the pigments involved in doves. However, very likely two types are involved in the plumage and eye color - - the eumelanin, black-browns, and phaeomelanin, red-yellows. These are very widespread among most all vertebrates. The gray plumage of dark doves becomes blackish in the neck ring, in the flight feathers and in the tail bar. Likely, the phaeomelanin is missing there. This notion is supported by the orange mutant (see Miller and Munsell, p. 5 Nov/Dec ADAN, 1985 issue), The tips of the tail feathers, especially toward the side (less in the middle ones) become whitish with no melanin or very little present. Juvenile dark doves and even blonds show a buff edge lacing that is most noticable in the wing shield coverts. This is lost in the adult plumage. A whitish trailing edge to some flight and secondary wing feathers is also seen. For a fuller description see Goodwin, D. , 1977, "Pigeons and Doves of the World".

82. EMedicine - Albinism : Article By Khalid Hasanee, MD
albinism albinism consists of a group of inherited abnormalities of melanin genetic studies, the classification of albinism has shifted emphasis to
http://www.emedicine.com/OPH/topic315.htm
(advertisement) Home Specialties Resource Centers CME ... Patient Education Articles Images CME Advanced Search Consumer Health Link to this site Back to: eMedicine Specialties Ophthalmology Genetic Disorders
Albinism
Last Updated: June 16, 2005 Rate this Article Email to a Colleague Synonyms and related keywords: oculocutaneous albinism, ocular albinism, melanin AUTHOR INFORMATION Section 1 of 10 Author Information Introduction Clinical Differentials ... Bibliography
Author: Khalid Hasanee, MD , Staff Physician, Department of Ophthalmology, Queen's University School of Medicine, Canada Coauthor(s): Iqbal Ike K Ahmed, MD, FRCSC , Clinical Assistant Professor, Department of Ophthalmology, University of Utah Khalid Hasanee, MD, is a member of the following medical societies: Canadian Ophthalmological Society Editor(s): Gerhard W Cibis, MD , Director of Pediatric Ophthalmology Service, Clinical Professor, Department of Ophthalmology, University of Kansas; Director, Clinical Professor, Department of Ophthalmology, Children's Mercy Hospital, University of Missouri at Kansas City; Francisco Talavera, PharmD, PhD

83. New England Reptile Distributors, Designer Ball Pythons, Reticulated Pythons, An
Simple Recessive genetics 101. At this point we ll assume that you ve alreadyread our Intro Note While we use albino ball pythons as our example here,
http://www.newenglandreptile.com/genetics_simple_recessive.html
The Most Extensive Collection of Ball Python Mutations in Captivity
NERD Herpetocultural Library Simple Recessive Genetics 101
At this point we'll assume that you've already read our Intro to Reptile Genetics page & are somewhat familiar with the terms we'll be using going forward. Most of the genetic terms on this page are "clickable" and will bounce you back to the glossary page if you need to refresh your memory.
General Information Simple Recessive Genes - what are they and what do they do? Simple recessive traits are proven, inheritable genes that are only visible in their homozygous form. When a homozygous animal is bred to a wild type normal ), non-gene-carrying animal, all of their resulting offspring will be normal in appearance, but will carry the gene from the homozygous parent. This is due to a mutated allele being passed on from the homozygous parent to the offspring, and a normal allele being passed on by the wild type parent. Since the two alleles are different, they dictate that the offspring's

84. Health Topics
albinism refers to a group of related conditions. The most accurate way todetermine albinism and the specific type is genetic testing.
http://www.netwellness.org/ency/article/001479.htm
NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Sunday, September 18, 2005 Home HealthTopics Health Centers Reference Library ... Search NetWellness
ADAM Health Encyclopedia
Injury Disease Nutrition Poison ... Z
Albinism
Definition
Albinism refers to a group of related conditions. These conditions are the result of altered genes that cause a defect of melanin production. This defect results in the partial or full absence of pigment from the skin, hair, and eyes.
Alternative Names
Hypopigmentation; Oculocutaneous albinism; Ocular albinism
Causes
Albinism results when the body is unable to produce or distribute pigment, called melanin, because of one of several possible genetic defects. In Type 1 albinism defects in the metabolism of tyrosine lead to failure in converting this amino acid to melanin. This is due to a genetic defect in tyrosinase the enzyme responsible for metabolizing tyrosine. Type 2 albinism is due to a defect in the "P" gene. Those with this type have slight pigmentation at birth. In the most severe form of albinism (called oculocutaneous albinism), those affected appear to have hair, skin, and iris color that are white or pink as well as vision defects. This is inherited via an autosomal recessive process.

85. AZ Genetics / Genetics Primer
For example, a guppy s body color, whether it is gold, red or albino is determined guppy is CC and that the genetic code for the albino guppy is cc.
http://www.arihood.com/azgenetics/genprimr1.html
Genetics Primer
Terms
Basics Dominance Appearances Calculations
Basics
Chromosome are found in pairs. Opposite each other on the chromosome pair are two genes which together determine a feature. The gene's position on the chromosome is called it's locus . For example, a guppy's body color, whether it is gold, red or albino is determined by two genes, both of which are located at the same locus (or location) on the chromosome pair.
When guppies mate, each parent provides half of the offspring's genes. The mother's and father's chromosomes each split so that there is no longer a pair, only half a pair. One chromosome from the father unites with one chromosome from the mother to form a new chromosome pair. When the genes match up at each locus, a new trait is established. Now, if the genes on both side of a locus are the same as the genes before the chromosome split during mating, then the feature will be identical to the parent. More often than not, this is not the case, so the offspring may have a different feature.
Let's take an example of this. It is known in the real world that a gene exists in guppies for wild coloring (full coloring) and albinism. We can create a chart which will show the results of a mating of these two types.

86. Albinism - Swedish Medical Center, Seattle, Washington
There are several dozen different genetic subtypes of albinism which affect For some types of albinism, DNA genetic testing can also be used to confirm
http://www.swedish.org/14134.cfm
PDF Version Search Send-to-Friend Health Library Home ... Conditions InBrief
Albinism
(Hypopigmentation, Oculocutaneous albinism, Ocular albinism)
by Rick Alan Definition Causes Risk Factors ... Prevention
Definition
Causes
Albinism occurs as a result of altered genes, which are in most cases are inherited from parents. Albinism appears in different forms and may be inherited by one of several modes: autosomal recessive, autosomal dominant, or X-linked.Autosomal recessive inheritance accounts for the vast majority of cases. This means that while both parents carry one copy of an abnormal gene, they have no symptoms or signs of albinism. Children become affected only if they inherit one affected gene from each parent. In this form of inheritance, each child has a one-in-four chance of inheriting the condition. The abnormal gene reduces (or completely eliminates) the bodys ability to make a pigment called melanin. There are several dozen different genetic subtypes of albinism which affect melanin production. Individuals can have full or partial absence of this pigment which will effect the color of eyes, hair and skin. Albinism is rare. In the United States about 1 in 17,000 inidividuals overall has some form of albinism. All races are affected, though Type 1 occurs predominantly in whites and Type 2 in blacks. Most children with albinism are born to parents with normal hair and skin color for their ethnic background. While albinism is always apparent at birth, it may be so mild that affected persons are unaware of their diagnosis unless abnormal eye movements or vision develop.

87. Rick Guidotti - About POSITIVE EXPOSURE
Why albinism? Is POSITIVE EXPOSURE working with other genetic onditions? albinism is a genetic condition that reduces or eliminates pigmentation in the
http://www.rickguidotti.com/about.htm

About

What is POSITIVE EXPOSURE? What does POSITIVE EXPOSURE do? Why is POSITIVE EXPOSURE needed? What has POSITIVE EXPOSURE accomplished so far? POSITIVE EXPOSURE has a unique focus on albinism. Why albinism? Is POSITIVE EXPOSURE working with other genetic onditions? What are the next steps? How can I find out more? What is POSITIVE EXPOSURE? POSITIVE EXPOSURE is a not-for-profit, 501(c)(3) organization whose innovative programs challenge the stigma associated with difference and celebrates the richness of genetic variation with positive images and powerful life stories. The program is a unique partnership between visual arts, genetics, mental health and human rights driven by former fashion photographer Rick Guidotti and Diane McLean, MD, PhD, MPH. BACK TO TOP OF PAGE
What does POSITIVE EXPOSURE do? Utilizing photography and video interviews, POSITIVE EXPOSURE investigates the social and psychological experiences of people living with genetic, physical and mental health conditions of all ages and ethnocultural heritages. POSITIVE EXPOSURE attacks public fears about difference with positive images and powerful life stories. POSITIVE EXPOSURE constructs a mirror that simultaneously reflects society's injustices and potentials, developing practical methods that demonstrate how personal transformation and social transformation are inextricably intertwined.

88. Albinism - Definition Of Albinism In Encyclopedia
albinism is a genetic condition resulting in a lack of pigmentation in the eyes,skin and hair. It is an inherited condition arising from the combination of
http://encyclopedia.laborlawtalk.com/albinism
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Albinism is a genetic condition resulting in a lack of pigmentation in the eyes, skin and hair. It is an inherited condition arising from the combination of recessive genes passed from both parents of an individual. A variety of problems with photosensitivity in eyesight and skin usually result from the condition. This article is intended to cover mainly human albinism, although many of the features mentioned would probably also apply to albinism in animals. Contents showTocToggle("show","hide") 1 Lack of Pigmentation
2 Classification

3 Visual Problems Associated with Albinism

4 Genetics
...
7 External links
Lack of Pigmentation
The gene which results in albinism prevents the body from making the usual amounts of a pigment called melanin There are many genes which are now scientifically proven to be associated with albinism (or better: alterations of the genes). All alterations, however, lead to an alteration of the melanin (pigment / colouring) production in the body. Melanin helps protect the skin from ultraviolet light coming from the Sun (see human skin color for more information). People with albinism lack this protective pigment in their skin, and can burn easily from exposure to the sun as a result. Lack of melanin in the eye often results in problems with vision, as the eye will not develop properly without the pigment.

89. Leopard Gecko Genetics - A Discussion Of Particular Leopard Gecko Morphs
Genetic Snow (coming soon). Double Recessive Morphs (Patternless Albino, BlazingBlizzard, etc.) DEFINTIONS. NORMAL PHENOTYPE (DOMINANT)
http://www.geckosetc.com/htm/genetics.htm
Leopard Gecko Genetics by Steve Sykes I understand many people have not studied genetics, so I will start by defining the basic terms. I have tried to simplify this subject as much as possible, and will explain concepts using leopard gecko examples whenever possible. DEFINTIONS:
Recessive trait

Line-bred trait

Phenotype

Genotype
...
Homozygous
MORPHS: LINE BRED TRAITS:
Hypo Tangerine, Super Hypo Tangerine, and Carrot Tail

Jungle (coming soon) RECESSIVE TRAITS: Albino Strains (Tremper, Rainwater, and Bell)
Patternless

Patternless Albino

Blizzard (coming soon) DOMINANT TRAITS: Tremper Giant (coming soon) Genetic Snow (coming soon) Double Recessive Morphs (Patternless Albino, Blazing Blizzard, etc.) DEFINTIONS: "NORMAL PHENOTYPE" (DOMINANT) RECESSIVE TRAIT This refers to traits that are not expressed when combined with a dominant trait. In order for a recessive trait to be expressed (outwardly visible) the gecko must be carrying two copies of that trait. Recessive traits in leopard geckos include all three strains of albino (Tremper, Rainwater (Las Vegas), and Bell), patternless, and blizzard. Selective breeding cannot create recessive traits. These traits are the result of a mutation of certain genes that control a specific part of the development of the animal. Recessive traits are usually discovered randomly, there is nothing you can do to increase your probability of discovering a new recessive trait, you just need to be lucky!

90. Albinism@Everything2.com
albinism is a genetic condition which is inherited from an individual s parents.For OCA, an individual must inherit an altered albinism gene from both
http://everything2.com/index.pl?node=Albinism

91. SupportPath.com: Albinism / Hypopigmentation
The Genetic Alliance describes itself as an international......Part of The National Organization for albinism and Hypopigmentation (NOAH)
http://www.supportpath.com/sl_a/albinism_hypopigmentation.htm
Albinism / Hypopigmentation
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  • INTERNATIONAL
    Genetic Alliance
    Website:
    http://www.geneticalliance.org/
    Description: The Genetic Alliance describes itself as "an international coalition of individuals, professionals and genetic support organizations that are working together to promote healthy lives for everyone impacted by genetics". Website includes links to disease information, info on genetic issues, and detailed descriptions of support groups and organizations.
    Date Added: 08/27/2002
  • UNITED STATES
    The National Organization for Albinism and Hypopigmentation (NOAH)
    Website:
    http://www.albinism.org/

92. African Origin Of An Intragenic Deletion Of The Human P Gene In Tyrosinase Posit
Oculocutaneous albinism (OCA) is a genetically heterogeneous JG Autosomalrecessive oculocutaneous albinism in man evidence for genetic heterogeneity.
http://www.nature.com/ng/journal/v7/n2/abs/ng0694-176.html
@import "/ng/style.css"; nature.com homepage Login Search This journal All of nature.com Advanced search Journal home Archive Table of Contents ... For librarians NPG Resources Nature Nature Cell Biology Nature Medicine Nature Reviews Genetics ... Browse all publications Article Nature Genetics
doi:10.1038/ng0694-176
African origin of an intragenic deletion of the human P gene in tyrosinase positive oculocutaneous albinism
D. Durham-Pierre , J. M. Gardner , Y. Nakatsu , R. A. King , U. Francke , A. Ching , R. Aquaron , V. del Marmol Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA Departments of Medicine and Pediatrics, and Institute of Human Genetics, University of Minnesota, Minneapolis, Minnesota 55455, USA Departments of Genetics and Pediatrics, and Howard Hughes Medical Institute, Stanford University Medical Center, Stanford, California 94305, USA Biological Laboratory, Children's Hospital, Marseille, France L.O.C.E., Institute J. Bordet, Brussels, Belgium Oculocutaneous albinism (OCA) is a genetically heterogeneous hypopigmentation disorder. One of the two major autosomal recessive forms involves the tyrosinase gene (

93. Lyons'Den Homepage
genetics. Breeds. Agouti. Brown. Color (sepia, points, albino). Research. Join theProject! Coat Color References. Testing Laboratories
http://faculty.vetmed.ucdavis.edu/faculty/lalyons/Sites/color.htm
back to the Lyons' Den) Feline Genome project Feline Genome Project Feline Projects Cranial Facial Abnormality Coat Colors/Fur Types Breed Diversity Cat Domestication Heart Disease Lymphoma Persian Retinal Atrophy Polycystic Kidney Disease "Spasticity"
(Cheek swabs, tissue, blood...) DNA tests available soon for coat colors! The mutations that cause several coat colors in cats have now been identified. DNA tests are being developed and will be available as commercial services soon. Tests for agouti, sepia, and points are available. Tests for complete albino, chocolate and cinnamon are under develeopment. Patents are pending for several tests, but licenses will be available to any interested DNA typing service laboratory, worldwide. All tests can be performed on DNA acquired from buccal (cheek) swabs. Calling all cats with unusual colors, such as goldens or carmels! We are actively seeking your DNA! Cats that are dominant white, hearing and non-hearing, are also highly desired! Please join our research! Background Genetics Breeds Agouti ... Color (sepia, points, albino)

94. Albinism -- Facts, Info, And Encyclopedia Article
albinism. Categories Congenital genetic disorders albinism is a (Click linkfor more info and facts about genetic) genetic condition resulting in a lack
http://www.absoluteastronomy.com/encyclopedia/a/al/albinism.htm
Albinism
[Categories: Congenital genetic disorders]
Albinism is a (Click link for more info and facts about genetic) genetic condition resulting in a lack of (Coloration of living tissues by pigment) pigmentation in the eyes, skin and hair. It is an inherited condition arising from the combination of (Gene that produces its characteristic phenotype only when its allele is identical) recessive gene s passed from both parents of an individual. A variety of problems with photosensitivity in (Normal use of the faculty of vision) eyesight and skin usually result from the condition. This article is intended to cover mainly human albinism, although many of the features mentioned would probably also apply to albinism in other animals.
Lack of pigmentation
The gene which results in albinism prevents the body from making the usual amounts of a (Dry coloring matter (especially an insoluble powder to be mixed with a liquid to produce paint etc)) pigment called (Insoluble pigments that account for the color of e.g. skin and scales and feathers) melanin . Albinism is typically categorised as (Click link for more info and facts about Tyrosinase) Tyrosinase positive or negitive. In cases of Tyrosinase positive albinism, the

95. Albino Plants, Alaska Science Forum
Article about studying genetics through albino plants. As in animals, albinismin plants is caused by lack of pigment. However, in plants the lack is
http://www.gi.alaska.edu/ScienceForum/ASF4/433.html
Alaska Science Forum
October 6, 1980 Albino Plants
Article #433 by John Zasada This article is provided as a public service by the Geophysical Institute, University of Alaska Fairbanks, in cooperation with the UAF research community. Guest author John Zasada is with the Institute of Northern Forestry, University of Alaska. Every once in a while the careful observer will run across an albino plant. Albino seedlings of Alaskan white spruce, aspen, birch and balsam poplar have been found, as have albino root suckers from aspen and fireweed plants. Other species of northern plants perhaps also exhibit occasional albinism. Albino seedlings probably result from the combination in the seed of genes that were recessive in the parent plants. The albino root suckers are thought to develop from mutation in a single cell or in a group of cells, because the rest of the plant from which the albino stem grows can be normal. As in animals, albinism in plants is caused by lack of pigment. However, in plants the lack is fatal because the missing pigment is chlorophyll. Without chlorophyll, the albino plant has no way to manufacture the food needed for survival and growth to maturity. Albino seedlings usually live only about a week, but albino root suckers tend toward a bit more longevity because they can draw food from the parent plant. Even though albino plants do not live long, their occurrence is useful to those who study forest genetics. The genes that create albinism can be used as markers to examine the rates and patterns of seed dispersal from those trees which carry those particular genes.

96. Vision Of Children - Childhood Blindness And Vision Impairment: Research Updates
Ocular albinism type 1 (OA1) is an Xlinked genetic disorder affecting exclusivelymale individuals, while females may be healthy carriers of the disease.
http://www.visionofchildren.org/research.html

Amelioration in Both Functional and Morphological Abnormalities in the Retina of a Mouse Model of Ocular Albinism Following AAV-Mediated Gene Transfer (2005) Scientific research into the use of gene therapy as a possible treatment for various types of diseases has been rapidly advancing in the recent years with one of the most prominent discoveries only beginning to unfold. Ocular albinism (OA), one form of the congenital hypopigmentary disease commonly referred to as albinism, is generally specific to the eye, though many confuse it with oculocutaneous albinism ( OCA In a recent study done by a group of Italian researchers at the Telethon Institute of Genetics and Medicine (TIGEM) in Naples,, the gene for OA1 (also known as GPR143) was transferred into a knockout (KO) mouse model that showed positive for symptoms similar to those suffering from OA1 including hypopigmentation in the ocular fundus (the back portion of the eye), the presence of macromelanosomes even at birth, and the abnormal crossing of the optic fibers at the chiasm (which is where the optic nerve fibers cross in the brain). Referred to as

97. Albino --  Britannica Student Encyclopedia
albinism is generally considered to be the first genetic disorder ever recognized.There are references to it as far back as the Old Testament.
http://www.britannica.com/ebi/article-9272784
Home Browse Newsletters Store ... Subscribe Already a member? Log in This Article's Table of Contents albino Print this Table of Contents Shopping Price: USD $1495 Revised, updated, and still unrivaled. The Official Scrabble Players Dictionary (Hardcover) Price: USD $15.95 The Scrabble player's bible on sale! Save 30%. Merriam-Webster's Collegiate Dictionary Price: USD $19.95 Save big on America's best-selling dictionary. Discounted 38%! More Britannica products albino
Student Encyclopedia Article Page 1 of 1
albino... (75 of 280 words) var mm = [["Jan.","January"],["Feb.","February"],["Mar.","March"],["Apr.","April"],["May","May"],["June","June"],["July","July"],["Aug.","August"],["Sept.","September"],["Oct.","October"],["Nov.","November"],["Dec.","December"]]; To cite this page: MLA style: "albino." Britannica Student Encyclopedia http://www.britannica.com/ebi/article-9272784
APA style:
albino. ( Britannica Student Encyclopedia . Retrieved http://www.britannica.com/ebi/article-9272784

98. 606952 ALBINISM, OCULOCUTANEOUS, TYPE IB; OCA1B
The authors suggested that the probands are genetic compounds for the yellowmutant allele and the classic albinism allele.
http://srs.sanger.ac.uk/srsbin/cgi-bin/wgetz?[omim-ID:606952] -e

99. Landmarks In The History Of Genetics [M.Tevfik DORAK]
1909 AE Garrod publishes Inborn Errors of Metabolism biochemical genetics ofalbinism, cystinuria, pentosuria and alkaptonuria; W Johannsen uses the words
http://dorakmt.tripod.com/genetics/notes01.html
Back to Contents Back to Evolution Back to HLA Back to MHC ... Homepage LANDMARKS IN THE HISTORY OF GENETICS M.Tevfik Dorak, MD, PhD Robert Hooke (1635-1703), a mechanic, is believed to give ' cells ' their name when he examined a thin slice of cork under microscope, he thought cells looked like the small, rectangular rooms monks lived. William Harvey suggests that all living things originate from eggs JR Camerarius does pollination experiments and discovers sex in flowering plants CV Linnaeus (originally Linne ) proposes the taxonomic system including the naming of Homo sapiens. JG Kolreuter finds in experiments on Nicotiana that each parent contributes equally to the characteristics of the offspring. TR Malthus publishes An Essay on the Principle of Population (foundations of the struggle for existence and the survival of the fittest). Karl Friedrich Burdach coins the term biology to denote the study of human morphology, physiology and psychology. JB de Monet Lamarck puts forward his ideas on evolution WC Wells suggests natural selection in African populations (for their relative resistance to local diseases) CF Nasse describes the sex-linked transmission of haemophilia TA Knight, J Goss, and A Seton independently do studies in peas and observe the dominance

100. Entrez PubMed
Six essential genes located near the mouse albino locus have been identified asrequired during spec
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1

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