Temin, Howard Martin temin, howard martin. (b. Dec. 10, 1934, Philadelphia, Pa., USd. Feb. 9, 1994,Madison, Wis.), American virologist who in 1975 shared the Nobel Prize for http://www.britannica.com/nobel/micro/585_99.html
Extractions: (b. Dec. 10, 1934, Philadelphia, Pa., U.S.d. Feb. 9, 1994, Madison, Wis.), American virologist who in 1975 shared the Nobel Prize for Physiology or Medicine with his former professor Renato Dulbecco and another of Dulbecco's students, David Baltimore , for his codiscovery of the enzyme reverse transcriptase. While working toward his Ph.D. under Dulbecco at the California Institute of Technology, Temin began investigating how the Rous sarcoma virus causes animal cancers. One puzzling observation was that the virus, the essential component of which is ribonucleic acid (RNA), could not infect the cell if the synthesis of deoxyribonucleic acid (DNA) was stopped. Temin proposed in 1964 that the virus somehow translated its RNA into DNA, which then redirected the reproductive activity of the cell, transforming it into a cancer cell. The cell would reproduce this DNA along with its own DNA, producing more cancer cells. Skeptics pointed out that Temin's suggestion contradicted the contemporary tenet of molecular biology: that genetic information always passed from DNA to RNA, rather than the reverse. But in 1970 both Temin and Baltimore proved Temin's hypothesis correct. They identified an enzyme (reverse transcriptase) in the virus that synthesizes DNA that contains the information in the viral RNA. Temin obtained his Ph.D. in 1959, and after spending another year with Dulbecco, he joined the faculty of the University of Wisconsin in Madison, where he taught and conducted research until his death.
Britannica Student Encyclopedia temin, howard martin American virologist who in 1975 shared the Nobel Prize forPhysiology or Medicine with his former professor Renato Dulbecco and another http://www.britannica.com/ebi/print_toc?tocId=9316935
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Howard Martin Temin temin, howard martin, 193494, American virologist, b. Philadelphia, Ph.D.California Institute of Technology, 1959. A professor at the Univ. of Wisconsin http://www.factmonster.com/ce6/people/A0848112.html
Extractions: Reference Desk Encyclopedia Temin, Howard Martin Temin, Howard Martin, , American virologist, b. Philadelphia, Ph.D. California Institute of Technology, 1959. A professor at the Univ. of Wisconsin in Madison, Temin began his cancer research while still a student, working with his professor Renato Dulbecco and fellow student David Baltimore . In 1970 they experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia, AD AD AD ADS Business Cards Link to Fact Monster Add Fact Monster search ... Privacy
Renato Dulbecco howard martin temin temin, howard martin, 193494, American virologist, b.Philadelphia, Ph.D. California David Baltimore - Baltimore, David , 1938, http://www.factmonster.com/ce6/people/A0816281.html
Extractions: Reference Desk Encyclopedia Dulbecco, Renato [r u Pronunciation Key Dulbecco, Renato Temin and David Baltimore , experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia, AD AD AD ADS Business Cards Link to Fact Monster Add Fact Monster search ... Privacy
Howard Martin Temin temin, howard martin (The Columbia Encyclopedia, Sixth Edition). temin, howardmartin (19341994) (The Hutchinson Encyclopedia). temin, howard martin (1934- http://www.infoplease.com/ce6/people/A0848112.html
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Renato Dulbecco howard martin temin temin, howard martin, 193494, American virologist, b. temin, howard martin (The Columbia Encyclopedia, Sixth Edition) http://www.infoplease.com/ce6/people/A0816281.html
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MSN Encarta - Temin, Howard Martin temin, howard martin (19341994), American virologist and winner of the 1975Nobel Prize in physiology or medicine, which he shared with American http://encarta.msn.com/encyclopedia_761582646/Temin_Howard_Martin.html
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Extractions: By Alphabet : Encyclopedia A-Z T Related Category: Cell Biology, Biographies Howard Martin Temin Dulbecco and fellow student David Baltimore . In 1970 they experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. About Us Contact Us Privacy Links Directory ...
Extractions: By Alphabet : Encyclopedia A-Z D Related Category: Medicine, Biographies Renato Dulbecco [r u O O Pronunciation Key Temin and David Baltimore , experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. About Us Contact Us Privacy Links Directory ...
Temin, Howard Martin temin, howard martin (19341994) temin was born in Philadelphia and educatedat Swarthmore College, Pennsylvania, and the California Institute of http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/T/Temin/1.html
Extractions: Article in a Box Howard Martin Temin Co-discoverer of Reverse Biological Information Flow S Mahadevan One of the first observations of Temin, working under the guidance of Harry Rubin, a post doc in Dulbecco's lab, was that when RSV was added to a sparse layer of chicken embryonic cells, infected centers showed up as foci, the cell-culture equivalents of tumours. Even today, this is an important assay for the tumerogenic potential of a virus. Temin also found that the morphology of the foci were different when genetic variants of the virus was used, leading to the important conclusion that transformation is the result of action by genes carried by the virus. Subsequent studies by others established that these are cellular genes `hijacked' by the virus, whose function has been modified. Thus it was realized that modification of normal cellular genes can lead to cancer. the viral RNA genome is used as a template to make a DNA copy that is integrated into the host genome. The DNA provirus is then used as a template that is transcribed to give the viral RNA copies.
Temin - YourDictionary.com - American Heritage Dictionary Search Mamma.com for temin . TYPE IN YOUR WORD CLICK GO! Search Tem·inListen t m n , howard martin 19341994. American oncologist. http://www.yourdictionary.com/ahd/t/t0096800.html
Caltech Nobel Site howard martin temin WILLIAM NUNN LIPSCOMB, JR. ROBERT WOODROW WILSON howard martin temin (19341994) howard temin shared the 1975 Nobel Prize in http://pr.caltech.edu/events/caltech_nobel/home2.html
Extractions: Kenneth Wilson was awarded the 1982 Nobel Prize in Physics for his work to construct improved theories about the transformations of matter called continuous, or second-order, phase transitions. His research led to a very general and effective mathematical strategy for understanding how complex microscopic behavior underlies gross macroscopic effects. Willy Fowler shared (with S. Chandrasekhar) the 1983 Nobel Prize in Physics for his work on nucleosynthesis, the process whereby the nuclei of lighter chemical elements fuse to create heavier ones. In groundbreaking work in the late 1950s, he and his colleagues demonstrated that, starting only with the hydrogen and helium produced in the Big Bang, all the elements from carbon to uranium could be produced by the nuclear processes in stars.
[ISI Highly Cited Researchers Version 1.1] Highly Cited Researcher temin, howard martin ISI Assigned Category,Microbiology. ISI Indexed Name, temin HM temin. ISI Notes, Deceased http://hcr3.isiknowledge.com/author.cgi?&id=1966
[ISI Highly Cited Researchers Version 1.1] Highly Cited Researcher temin, howard martin Pathak, VK, temin, HM BROADSPECTRUMOF INVIVO FORWARD MUTATIONS, HYPERMUTATIONS, AND MUTATIONAL HOTSPOTS http://hcr3.isiknowledge.com/formViewCharacteristic.cgi?table=Publication&link1=
Articles - Howard Martin Temin under the terms of the GNU Free Documentation License Source Original textfrom the article in Wikipedia, The Free Encyclopedia howard martin temin. http://www.1-electric.com/articles/Howard_Temin
Extractions: Howard Martin Temin December 10 February 9 ) was a U.S. geneticist . He discovered reverse transcriptase University of Wisconsin-Madison . He won a Nobel Prize in Physiology or Medicine in for describing how tumor viruses act on the genetical material of the cell through reverse transcriptase. This upset the widely held belief at the time of the "Central Dogma" of molecular biology posited by Nobel laureate Francis Crick , one of the co-discoverers of the structure of DNA (along with James Watson and Rosalind Franklin ). Crick, along with most other molecular biologists of the day, believed genetic information to flow exclusively from DNA to RNA to protein . Temin showed that certain tumor viruses carried the enzymatic ability to reverse the flow of information from RNA back to DNA using reverse transcriptase. This phenomenon was also independently studied by David Baltimore , with whom Temin shared the Nobel Prize. The discovery of reverse transcriptase is one of the most important of the modern era of medicine, as reverse transcriptase is the central enzyme in several widespread human diseases, such as HIV , the virus that causes AIDS , and Hepatitis B . Reverse transcriptase is also an important component of several important techniques in molecular biology and diagnostic medicine, such as the polymerase chain reaction (PCR).
