Extractions: Fred Sanger and his colleagues developed many of the techniques still used in genomic biology to this day. The fundamental method of 'reading' DNA using special bases called chain terminators, the use of very thin gel systems, the adaptation of efficient cloning methods to produce both DNA strands and the whole-genome shotgun were all developed by Fred and his group during the 1970s. Fred's group produced the first DNA whole genome sequence (for a virus called phiX174 that grows in bacteria) of just over 5000 base-pairs. They went on to sequence the first human genome (albeit that of the DNA in mitochondria - small energy factories in all our cells that have their own genome of about 16,000 base-pairs) and the genome of an important virus for molecular biology, bacteriophage lambda, in 1982. To sequence this virus genome - about 48,000 base-pairs - Fred developed the whole-genome shotgun method. The sequence of lambda was the first whole-genome shotgun. Fred was born towards the end of the First World War in Gloucestershire, UK. His father was a GP from whom he gained an interest in biology. Fred took his first degree at
Laureates Of Tomorrow Nobel Essay Contest frederick sanger, the winner of the Nobel Prize in Chemistry in 1958 and 1980, frederick sanger was a chemistry pioneer, whose work with proteins and http://www.nyas.org/programs/nobel/essay7.html
Extractions: Poly Prep Country Day School, Brooklyn It is a rare honor to be selected as a Nobel laureate in chemistry by The Royal Swedish Academy of Sciences. An even greater tribute is to be selected as a Nobel Laureate twice. Frederick Sanger, the winner of the Nobel Prize in Chemistry in 1958 and 1980, is a scientist whose research embodies the tireless spirit of Alfred Nobel. Sanger first began studying the problems associated with determining the structure of proteins in 1943, but, following the receipt of his first Nobel Prize, his focus shifted from proteins to nucleic acids. In 1980 he received his second Nobel Prize for developing a technique for determining the base sequence in nucleic acids. His work with both proteins and nucleic acids has greatly contributed to science and has helped put molecular genetic studies at the forefront. Works Cited
Frederick Sanger (1955) 1955. frederick sanger (Cambridge) determines the sequence of amino acids ininsulin (Nobel Prize for Chemistry 1958) http://www.bioss.sari.ac.uk/~dirk/genomeOdyssey/go_1955.html
Dr. Frederick Sanger British biochemist and molecular biologist Dr. frederick sanger is a two timeNobel Prize winner. sanger won the 1958 Nobel Prize in chemistry for his http://www.myhealthspan.com/sanger.shtm
Extractions: Preventive Medicine: Your Key to a Long and Healthy Life Home Page Newsletters FAQs H-SCAN Physical Age Test ... Our Results British biochemist and molecular biologist Dr. Frederick Sanger is a two time Nobel Prize winner. Sanger won the 1958 Nobel Prize in chemistry for his research on the structure of proteins. The work that won Sanger his second Nobel Prize also led to his development of the Sanger Sequencing Method which is the major DNA decoding technique used in the International Human Genome Project which has major health and antiaging implications . In 1980 he shared the Nobel Prize in chemistry with American biochemists Paul Berg and Walter Gilbert for their work on determining the base sequences in nucleic acids. Born in Rendcomb, England, Sanger received both his B.A. degree (1939) and his Ph.D. degree (1943) from the University of Cambridge. He then joined the research laboratory headed by A. C. Chibnall, professor of biochemistry at Cambridge. In 1951 he joined the staff of the Medical Research Council and became one of the heads of the Council's molecular biology laboratory at Cambridge in 1961. Sanger retired from the Medical Research Council in 1983. Sanger's initial research focused on determining protein's structure, utilizing chromatography techniques (analytical techniques used to separate substances) established by British biochemists Archer Martin and Richard Synge. Using the protein insulin, which was relatively small in size and available in large quantities, Sanger developed a new method for analyzing protein and showed that a molecule of insulin contains two peptide chains made of two or more amino acids that are linked together by two disulfide bonds. It took eight more years to finally identify the 51 amino acids that make up insulin. For this work Sanger was awarded his first Nobel Prize in 1958. Sanger's research facilitated further advances in the field of biochemistry by British biochemists John Kendrew and Max Perutz, who in 1960 were able to prepare three-dimensional models of protein molecules.
Nobel Prizes Sabatier, Paul sanger, frederick (his first Nobel prize) sanger, frederick Seaborg,Glenn Theodore Semenov, Nikolai Nikolaevich Soddy, frederick Stanley, http://hilltop.bradley.edu/~rbg/Nobel.html
Chemistry Of Life: FacesThe Human Dimension frederick sanger. Courtesy MRC Laboratory of Molecular Biology. frederick sangerhas the very rare distinction of having won two Nobel Prizes, http://www.chemheritage.org/explore/life-sanger.html
Untitled frederick sanger B. 1918 D. Protein Sequencing Dideoxy-Sequencing. Researcher ofproteins, especially insulin; Created a technique for sequencing proteins http://www2.carthage.edu/~pfaffle/hgp/Sanger.html
Extractions: Researcher of proteins, especially insulin Created a technique for sequencing proteins using chemicals to cleave off one amino acid at a time and determine its identity through paper chromatography and 1-D and 2-D gel electrophoresis Won Nobel Prize in 1958 for determining amino acid sequence of insulin Colleagues like Francis Crick at the newly built Cambridge Laboratory of Molecular Biology sparked his interest in nucleic acids Created dideoxy-sequencing technique for determining nucleic acid sequences Dideoxy-sequencing works by incorporating dideoxy bases into a strand of DNA that is being formed from a template strand. The dideoxy bases halt elongation and result in randomly-sized strands. These strands can be run out on a gel and the gel is read from the bottom to the top to determine nucleic acid sequence Determined the nucleic acid sequence of the genome of bacteriophage, phi-X 174 Won Nobel Prize in 1980 with Walter Gilbert and Paul Berg for their nucleic acid research Sanger Center, named in his honor, is now one of the largest genome research facilities
MSN Encarta - Sanger, Frederick sanger, frederick (1918 ), British biochemist and Nobel laureate. sanger wasborn in Rendcombe, Gloucestershire, and educated at the University of http://uk.encarta.msn.com/encyclopedia_761574882/Sanger_Frederick.html
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Escolar.com - Biografia De Sanger, Frederick Translate this page sanger, frederick. (Rendcombe, Reino Unido, 1918) Bioquímico británico. Tras sugraduación, en 1939, en la Universidad de Cambridge, permaneció en esta http://www.escolar.com/biografias/s/sanger.htm
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Frederick Sanger -- Facts, Info, And Encyclopedia Article frederick sanger. Categories Nobel Prize in Chemistry winners, fredericksanger (Click link for more info and facts about OM) OM (born August 13, http://www.absoluteastronomy.com/encyclopedia/f/fr/frederick_sanger.htm
Extractions: Frederick Sanger (Click link for more info and facts about OM) OM (born August 13, 1918) is an (An Indo-European language belonging to the West Germanic branch; the official language of Britain and the United States and most of the Commonwealth countries) English (Someone with special training in biochemistry) biochemist and currently the only person who has been awarded two (An annual award for outstanding contributions to chemistry or physics or physiology and medicine or literature or economics or peace) Nobel prizes in (The science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions) Chemistry Sanger was educated at PrintLink("http://www.bryanston.co.uk/", "Bryanston School") and then did his (A bachelor's degree in arts and sciences) Bachelor of Arts in Natural Sciences at (Click link for more info and facts about St John's College, Cambridge) St John's College, Cambridge
MSN Encarta - Sanger, Frederick Translate this page sanger, frederick (1918- ), biochimiste britannique et lauréat du prix Nobel dechimie pour Autres fonctionnalités Encarta. Rechercher sanger, frederick http://fr.encarta.msn.com/encyclopedia_761574882/Sanger_Frederick.html
Nobel Prizes In Molecular Biology sanger, frederick, Great Britain, Cambridge University, b. sanger, frederick,USA, Great Britain, MRC Laboratory of Molecular Biology, Cambridge, b. http://home.sandiego.edu/~cloer/molecnobels.html
Extractions: Official Nobel Website (San Diego Supercomputing Center mirror) Chemistry 1958 The prize was awarded to: "for his work on the structure of proteins, especially that of insulin". Nobel e-Museum Link Physiology or Medicine 1958 The prize was divided, one half being awarded jointly to: "for their discovery that genes act by regulating definite chemical events"; and the other half to: "for his discoveries concerning genetic recombination and the organization of the genetic material of bacteria". Nobel e-Museum Link Physiology or Medicine 1959 The prize was awarded jointly to: SEVERO OCHOA, U.S.A., New York University, New York; and ARTHUR KORNBERG, U.S.A., Stanford University, Stanford, CA;
Nobel Prize Winning Chemists frederick sanger. The Nobel Prize In Chemistry 1958 1980. frederick sanger wasborn on August 13, 1918, at Rendcombe in Gloucestershire, the second son of http://www.sanbenito.k12.tx.us/district/webpages2002/judymedrano/Nobel Winners/f
Extractions: Nobel Prize Winning Chemists Frederick Sanger Frederick Sanger was born on August 13, 1918, at Rendcombe in Gloucestershire, the second son of Frederick Sanger, M. D. , a medical practitioner and his wife Cicely. He was educated at Bryanston School and at St. John's College, Cambridge, where he took his B. A. degree in natural sciences in 1939. Since 1940 he has carried out research in the Department of Biochemistry at Cambridge. From 1940 to 1943 he worked with Dr. A. Neuberger on the metabolism of the amino acid lysine and obtained a Ph. D. degree in 1943. Since 1943 his work has been concerned largely with problems related to the determination of the structure of proteins. These studies resulted in the determination of the structure of insulin. In 1940, he married Margaret Joan Howe; they have two sons and one daughter. Sanger was awarded the Corday-Morgan Medal. He was recipient of the Nobel Prize for Chemistry 1958 "for his work on the structure of proteins, especially that of insulin", he was also awarded the Nobel Prize for Chemistry together with Walter Gilbert "for their contributions concerning the determination of base sequences in nucleic acids". Back To Main Page
Extractions: Sie sind hier: Startseite Lexikon Frederick Sanger Frederick Sanger Frederick Sanger OM 13. August in Rendcombe, Grobritannien ) ist ein britischer Biochemiker Er erhielt f¼r die Aufkl¤rung der Struktur des Insulins und seiner Arbeiten zur Proteinsequenzierung im Jahre als alleiniger Tr¤ger den Nobelpreis f¼r Chemie und f¼r Untersuchungen zur Ermittlung der Basensequenz in Nukleins¤uren im Jahre erneut den Nobelpreis f¼r Chemie (diesmal zusammen mit Paul Berg und Walter Gilbert Inhaltsverzeichnis showTocToggle("Anzeigen","Verbergen") 1 Schule und Studium
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