Gertrude B. Elion: Definition And Much More From Answers.com She and colleague george hitchings developed drug treatments for leukemia, before becoming an assistant to george H. hitchings at the BurroughsWellcome http://www.answers.com/topic/gertrude-b-elion
Extractions: American drug researcher. She shared a 1988 Nobel Prize for developing drugs to treat leukemia and gout. Encyclopedia Elion, Gertrude Belle Äl ÄÉn ) , 1918â99, American pharmacologist, b. New York City, B.S. Hunter College, 1937. Unable to find research work (largely because she was a woman), she taught high school chemistry before joining Burroughs Wellcome Laboratories in 1944. She and colleague George Hitchings developed drug treatments for leukemia, rheumatoid arthritis, gout, viral herpes, urinary and respiratory tract infections, and AIDS. In 1988 the pair shared the Nobel Prize in Physiology or Medicine with British pharmacologist Sir James Black Medical El·i·on Äl Ä-Én, -Ån Gertrude Belle Born 1918.
Hitchings, George Herbert george H. hitchings reacting to questions at a press conference after it wasannounced he had won the Nobel Prize for Physiology or Medicine, 1988 http://www.britannica.com/nobel/micro/272_65.html
Extractions: George H. Hitchings reacting to questions at a press conference after it was announced he had won the Nobel Prize for Physiology or Medicine, 1988 UPI/Corbis-Bettmann (b. April 18, 1905, Hoquiam, Wash., U.S.d. Feb. 27, 1998, Chapel Hill, N.C.), American pharmacologist who, along with Gertrude B. Elion and Sir James W. Black , received the Nobel Prize for Physiology or Medicine in 1988 for their development of drugs that became essential in the treatment of several major diseases. Hitchings received his bachelor's and master's degrees from the University of Washington and earned a Ph.D. in biochemistry at Harvard University in 1933. He taught at Harvard until 1939, and in 1942 he joined the Burroughs Wellcome Laboratories, at which he conducted research until his retirement in 1975. Over a span of nearly 40 years, Hitchings worked with Elion, who was first his assistant and then his colleague in research at Burroughs Wellcome. Together they designed a variety of new drugs that achieved their effects by interfering with the replication or other vital functions of specific pathogens (disease-causing agents). In the 1950s they developed thioguanine and 6-mercaptopurine (6MP), which became important treatments for leukemia. In 1957 their alteration of 6MP produced the compound azathioprine, which proved useful in treating severe rheumatoid arthritis and other autoimmune disorders and in suppressing the body's rejection of transplanted organs. Their new drug allopurinol was an effective treatment for gout. Other important drugs that were developed by Hitchings and Elion include pyrimethamine, an antimalarial agent; trimethoprim, a treatment for urinary and respiratory tract infections; and acyclovir, the first effective treatment for viral herpes.
Hitchings, George Herbert -- Encyclopædia Britannica george H. hitchings,Jr Nobel Foundation Autobiography of this American radioastronomer, physicist, and Nobel laureate. george Herbert Walker Bush http://www.britannica.com/eb/article-9040608
Extractions: Home Browse Newsletters Store ... Subscribe Already a member? Log in Content Related to this Topic This Article's Table of Contents George Herbert Hitchings Print this Table of Contents Shopping Price: USD $1495 Revised, updated, and still unrivaled. The Official Scrabble Players Dictionary (Hardcover) Price: USD $15.95 The Scrabble player's bible on sale! Save 30%. Merriam-Webster's Collegiate Dictionary Price: USD $19.95 Save big on America's best-selling dictionary. Discounted 38%! More Britannica products Hitchings, George Herbert
National Academy Of Sciences - Deceased Member Testing 1 .. 2 .. 3 Advanced Search. hitchings, george H. Date of Birth,April 18, 1905. Elected to NAS, 1977. Date of Death, February 27, 1998. http://www4.nationalacademies.org/nas/nasdece.nsf/(urllinks)/NAS-58MV8Z?opendocu
History The NAS Building Legal Documents Giving To The National hitchings, george H. Hoagland, Dennis R. Hoard, James L. Hockett, Charles F.Hodge, William V. Hodgkin, Alan Hodgkin, Dorothy Hoeffding, Wassily http://www4.nationalacademies.org/nas/nasdece.nsf/urllinks/$$AlphaListH?OpenDocu
George Hitchings Editor s note george H. hitchings died on February 27, 1998, george H.hitchings, 27, knew he d been considered for the Nobel Prize in medicine. http://www.washington.edu/alumni/columns/march98/hitchings.html
Extractions: George H. Hitchings [Editor's note: George H. Hitchings died on February 27, 1998, just a few days after this issue was printed.] George H. Hitchings, '27, knew he'd been considered for the Nobel Prize in medicine. He'd already received many other awards for his basic research on designing drugs, which led to the development of medications for various cancers and bacterial infections, as well as AIDS, herpes, gout, malaria and transplantation. Still, he was surprised when he won. At 83, he thought he was too old to be considered anymore, though he was still hard at work in science and philanthropy, as president of the Burroughs Wellcome Fund in Research Triangle Park, N.C. His only regret was that his first wife could not be by his side when he accepted the prize. Beverly Reimer Hitchings died in 1985, after 52 years of marriage. His second wife, physician Joyce Shaver Hitchings, shared Hitchings' story, as he is now blind, has Alzheimer's disease, and could not be interviewed. "He's still enjoying family, old friends, music. The physcial beauty of Nature has become more vivid," she says. "We live near a lake, which reminds him of Puget Sound and Friday Harbor, where he did research." In September 1988, shortly before the prize announcement, Hitchings had started a whirlwind courtship with Joyce Shaver, 26 years his junior. When the prize was announced the next month, she recalled, "My first thought was, `Oh no, I've lost him to the world.' "
After The Prize: The UW's Nobel Laureates Editor s note george H. hitchings died on February 27, 1998, just a few daysafter this issue was printed. Each laureate had a distinct story to tell http://www.washington.edu/alumni/columns/march98/nobels1.html
Extractions: by Rebecca Hughes Seven men from the University of Washingtonfour professors and three alumnihave won the Nobel Prize . Bombarded by the media, showered with invitations and suddenly given thousands of dollars in prize money, the time of the announcement is a heady experience. But we wondered what happened next. Do you live happily ever after, both personally and professionally? Or should you be careful what you wish for, lest your dreams come true? Columns tracked down the half-dozen UW laureates still living to find out. Our four faculty members continue to live in Seattle: Physics Professor Hans G. Dehmelt, who shared the 1989 prize in physics; Medicine and Oncology Professor Emeritus E. Donnall Thomas, who shared the 1990 prize in medicine for his work at the Fred Hutchinson Cancer Research Center; and Pharmacology and Biochemistry Professor Emeritus Edwin G. Krebs and Biochemistry Professor Emeritus Edmond H. Fischer, who together shared the 1992 in medicine. Surprisingly, the two living alumni laureates live only a few miles apart in North Carolina: George H. Hitchings, `27, who shared the 1988 prize in medicine; and Martin Rodbell, `54, who shared the 1994 prize in medicine. Our first laureate, George J. Stigler, `31, who won the 1982 Nobel Prize in economics, died in 1991.
George H. Hitchings -- Facts, Info, And Encyclopedia Article george H. hitchings. Categories Pharmacologists, Seattleites george H.hitchings (19051998) shared the 1988 (Click link for more info and facts about http://www.absoluteastronomy.com/encyclopedia/G/Ge/George_H._Hitchings.htm
Extractions: George H. Hitchings (1905-1998) shared the 1988 (Click link for more info and facts about Nobel Prize in Physiology or Medicine) Nobel Prize in Physiology or Medicine with (Click link for more info and facts about Sir James Black) Sir James Black and (Click link for more info and facts about Gertrude Elion) Gertrude Elion "for their discoveries of important principles for drug treatment," Hitchings specifically for his work on (The use of chemical agents to treat or control disease (or mental illness)) chemotherapy Hitchings was born in (Click link for more info and facts about Hoquiam, Washington) Hoquiam, Washington , in 1905, and grew up there, in (Click link for more info and facts about Berkeley, California) Berkeley, California (A picturesque city of southern California on San Diego Bay near the Mexican border; site of an important naval base) San Diego (Click link for more info and facts about Bellingham, Washington) Bellingham, Washington
MSN Encarta - Hitchings, George Herbert hitchings, george Herbert (19051998), American chemist and Nobel Prize winner,born in Hoquiam, Washington. george H. hitchings Nobel Foundation http://encarta.msn.com/encyclopedia_761582630/Hitchings_George_Herbert.html
Extractions: Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Hitchings, George Herbert Hitchings, George Herbert (1905-1998), American chemist and Nobel Prize winner, born in Hoquiam, Washington. He received a Ph.D. degree from Harvard... Multimedia Selected Web Links George H. Hitchings [Nobel Foundation] 1 item Want more Encarta? Become a subscriber today and gain access to: Find more about Hitchings, George Herbert from Other Features from Encarta Search Encarta for Hitchings, George Herbert
American Red Cross - George H Hitchings Center Detail information for American Red Cross george H hitchings Center. http://yellowpages.thetimesnews.com/American Red Cross - George H Hitchings Cent
Extractions: Contact American Red Cross - George H Hitchings Center Phone: Fax: Email: Web: Map: 4737 University Dr Business Profile for American Red Cross - George H Hitchings Center Description: Hours: Payment: Since: Estimates: Discounts: Services: Brands: Are you familiar with American Red Cross - George H Hitchings Center?
George Hitchings The lives of george hitchings Jr. and Gertrude Belle Elion intersected in 1944 when george H. hitchings, Jr. autobiography from the Nobel eMuseum. http://www.chemheritage.org/EducationalServices/pharm/chemo/readings/hitch.htm
Extractions: Pharmaceutical Achiever The lives of George Hitchings Jr. and Gertrude Belle Elion intersected in 1944 when Hitchings, working at Burroughs Wellcome in New York, hired Elion to work with him as an assistant in the biochemistry department of the Wellcome Research Laboratories. For the next 30 years the pair collaborated on drug research that brought them both a Nobel Prize in 1988, for "important principles of drug development." Hitchings was born on the Olympic Peninsula in Washington state in 1905. As with Elion, the death of a close family member combined with an admiration for science led Hitchings to set his sights on a career in the medical and chemical sciences. "My father died after a prolonged illness when I was twelve years old," Hitchings once wrote. "The deep impression made by this event turned my thoughts toward medicine. This objective shaped my selection of courses in high school and expressed itself when I was salutatorian at my class graduation. I chose the life of [Louis] Pasteur as the subject for my oration. The blending of Pasteur's basic research and practical results remained a goal throughout my career."
George Hitchings - Teacher's Guide george H. hitchings, Jr. autobiography from the Nobel eMuseum. The Reconstructors be the drug discoverer in this postapocalyptic sci-fi drug http://www.chemheritage.org/EducationalServices/pharm/tg/chemo/readings/hitch.ht
Extractions: Pharmaceutical Achiever Using the Biographies This reading tells the story of George Hitchings, one of the developers of "rational drug design" along with Gertrude Elion. Hitchings and Elion were awarded The Nobel Prize in Medicine or Physiology in 1988. For more information, at other Web sites... Relevant National Science Education Standards Science as Inquiry Students should realize that both Hitchings' and Elion's research began with questions such as How do cells reproduce? then proceeded to questions like What compounds can we use to limit the reproduction of cancer cells? Furthermore, when compounds were found that had some impact on the reproduction of cancer cells, there were still questions to be answered, such as How can we alter the strucutre of this molecule to make it a more effective cancer drug? The students should grasp that it is through scientific experimentation that Hitchings or any other researcher answers the questions facing them. Physical Science The molecular nature of matter is central to Hitchings' research, especially the concept that altering the structure of a molecule alters its properties, and this is how Hitchings was able to create new molecules to treat cancer. The students should realize it was by a process of gradually altering the molecular structures of drug-candidates was he able to tweak their properties until he arrived at safe and effective anticancer medicines.
Grays Harbor Community Foundation - Our Scholarships Born in Hoquiam in 1905, george H. hitchings grew up in a family of shipbuilders.hitchingss father, george, Sr., worked at and eventually managed the http://www.gh-cf.org/list_of_scholarships.htm
Extractions: SCHOLARSHIP BIOGRAPHIES It is important to remember that most people who establish scholarships do so to honor or remember someone very dear to them. Commonly it is out of the grief of losing a loved one that a person will desire to create a scholarship. We include biographies for each scholarship to remember those in honor of whom our scholarships are named. We encourage students who apply to our program to remember that the people who established these scholarships all hope that their success as students and in life will, in time, increase the richness of our communities. Perhaps, we hope, the recipients of these scholarships today will someday give back to the community some measure of what our community has given them. Such shared generosity is what inspires our greatest sense of living in community. These links allow you to read the biography for a particular scholarship: Grays Harbor Community Foundation Scholarships LYLE LANCASTER MEMORIAL SCHOLARSHIPS Lyle Lancaster, a life-long Grays Harbor resident and businessman, directed in his will that his entire estate should be used to establish a permanent scholarship endowment fund for gifted students from Grays Harbor and Pacific Counties. This fund, established in 1999 upon Lyles death, is now the core of the Grays Harbor Community Foundations scholarship program.
Extractions: By Alphabet : Encyclopedia A-Z H Related Category: Medicine, Biographies George Herbert Hitchings Elion developed drug treatments for leukemia, rheumatoid arthritis, gout, viral herpes, urinary and respiratory tract infections, and AIDS. In 1988 the pair shared the Nobel Prize in Physiology or Medicine with British pharmacologist Sir James Black Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. About Us Contact Us Privacy Links Directory ...
AllRefer.com - Online Encyclopedia Topics H : Hes - Hof hitchings, george Herbert Hitler, Adolf Hitopadesa Hitoyoshi Hittite Hittite art and architecture Hittites Hittorff, Jacques Ignace http://reference.allrefer.com/encyclopedia/topics-a-z/H4.html
Extractions: Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. About Us Contact Us Privacy Links Directory ...
Science Center Nobel Laureates george H. hitchings was a senior instructor in Western Reserve University sDepartment of Biochemistry (193942), and emerged as one of the most productive http://www.cwru.edu/menu/sciencecenter/nobel_laureates.htm
Extractions: middle Nobel Laureates CWRU Home Page Welcome to CWRU! Admissions Academics University Departments Computing Resources University Libraries Research Student Life Alumni Relations News of CWRU Newsstand CWRU Directory Master Plan University Library Career Planning and Placement Undergraduate Admissions School of Graduate Studies Office of University Communication Thu. Sep 15 2005 Those professors and/or graduates from Case Western Reserve University
Shaver-Hitchings Scholarship The Shaver hitchings Scholarship Fund was created in 1990 by Dr. george H.hitchings and Dr. Joyce Shaver hitchings for the purpose of honoring and http://www.fis.ncsu.edu/grad_fellows/2537.html
Extractions: SHAVER-HITCHINGS SCHOLARSHIP SPONSORING AGENCY: Shaver-Hitchings Scholarship Fund PURPOSE: The Shaver Hitchings Scholarship Fund was created in 1990 by Dr. George H. Hitchings and Dr. Joyce Shaver Hitchings for the purpose of honoring and rewarding individuals with a commitment to helping others in the area of drug and alcohol addiction. FIELDS: The scholarship is available to any graduate student, physician's assistant, or medical student in the Triangle area who has worked (preferably as a volunteer) to help others with alcoholism, drug abuse and addictive disorder treatment or with preventative education on the subject of addiction. ELIGIBILITY: Applicants must reside in Chatham, Durham, Orange, or Wake Counties, and be enrolled or planning to enroll in graduate school, a physician assistant program, or medical school. There are no limitations on age or income level. Scholarships may be used to begin a new program of study or continue a program in which the applicant is already enrolled. The student need not be pursuing a degree in addictive disorders, but must show demonstrated commitment to working with others in that field during or before graduate studies, preferably as a volunteer.
Biography Of Hitchings, George H(erbert) Biographies of people living and dead of all nations. http://www.allbiographies.com/biography-GeorgeHerbertHitchings-37001.html
Extractions: Program BWF also supports another award program that is open to U.S. and Canadian postdoctoral biomedical scientists who want to study in the United Kingdom or Ireland. Career Awards in the Biomedical Sciences provide support ranging from $445,000 for four years to $574,000 for six years to bridge the advanced postdoctoral years and the first three years of faculty service. Candidates must have completed at least 12 months but not more than 48 months of postdoctoral training by the application deadline (October 1, 1999). Hitchings-Elion Fellowships support U.S. and Canadian researchers in the biomedical sciences and medically oriented behavioral sciences who want to pursue postdoctoral training in the United Kingdom or the Republic of Ireland. The awards are intended to help researchers early in their careers make the critical transition to becoming independent investigators, and to promote collaboration among scientists in the countries involved. The fellowships provide $332,500 over five years. It is anticipated that up to five fellowships will be awarded.
Triangle Community The 2004 george H. hitchings New Investigator Awards in Biomedical Research,which support Trianglearea graduate students, went to Seth Margolis and Yee http://www.bwfund.org/news/focus/archive/winter 2004/Triangle Community.html
Extractions: Winter 2004 breadCrumbs("http://www.bwfund.org/focus"," ","index.html","blurbContent","blurbContent","None","0"); Triangle Community Foundation Makes BWF-sponsored awards in honor of George Hitchings and Trudy Elion Three young researchers at Duke University have won Triangle Community Foundation awards, sponsored by BWF in honor of Nobel laureates George Hitchings and Trudy Elion. The 2004 George H. Hitchings New Investigator Awards in Biomedical Research, which support Triangle-area graduate students, went to Seth Margolis and Yee Lam. Margolis, a fourth year graduate student in pharmacology and cancer biology in the laboratory of Sally Kornbluth, is a 1997 graduate of the University of Rochester. His work focuses on understanding cell cycle progression using extracts from Xenopus oocytes arrested at mitosis. Lam, a second year graduate student in mechanical engineering and materials science, earned bachelors and masters degrees at the Massachusetts Institute of Technology in 2001 and 2002. She is interested in using atomic force microscopy (AFM) to understand how antigens and antibodies interact. Drs. Hitchings and Elion, co-recipients of the 1988 Nobel Prize for Physiology and Medicine for their critical insight that drugs interfering with DNA and RNA metabolism could provide routes to cures for cancer and infectious diseases, were strong supporters of BWF and tireless advocates of young scientists. Hitchings also was instrumental in the 1983 launch of the Triangle Community Foundation and donated his Nobel Prize money to the organization in 1989.
