1. Gene Therapy Definition, hurdles, ethical issues, and links to more resources on gene therapy provided by the Oak Ridge National Laboratory. http://www.ornl.gov/sci/techresources/Human_Genome/medicine/genetherapy.shtml

Human Genome Project Information Genomics:GTL Microbial Genome Program home ... skip navigation Gene Therapy Subject Index Send the url of this page to a friend Basic Information FAQs Glossary Acronyms Links ... Media Guide About the Project What is it? Goals Progress History ... Genetics 101 the New Genetics Home Gene Testing Gene Therapy Pharmacogenomics ... Genetic Counseling Ethical, Legal, Social Issues Home Privacy Legislation Gene Testing Patenting ... Genetics in Courtroom Education Teachers Careers Students Webcasts Audio/Video ... Genética Websites en Español Research Home Sequencing Instrumentation Mapping ... Funding Publications Human Genome News Chromosome Poster Primer Molecular Genetics To Know Ourselves ... List of All Publications Search This Site Contact Us Privacy Statement Site Stats and Credits Quick Links to this page What is gene therapy? How does gene therapy work? What is the current status of gene therapy research? What factors have kept gene therapy from becoming an effective treatment for genetic disease? ... Gene therapy links What is gene therapy? Gene therapy is a technique for correcting defective genes responsible for disease development. Researchers may use one of several approaches for correcting faulty genes:

2. Gene Therapy - Wikipedia, The Free Encyclopedia gene therapy is the insertion of genes into an individual s cells and tissues to treat a disease, and hereditary diseases in which a defective mutant allele http://en.wikipedia.org/wiki/Gene_therapy

Gene therapy From Wikipedia, the free encyclopedia Jump to: navigation search Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease , and hereditary diseases in which a defective mutant allele is replaced with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is a genetically-mediated therapy and is often considered together with other methods. Gene therapy using an Adenovirus vector. A new gene is inserted into an adenovirus vector, which is used to introduce the modified DNA into a human cell. If the treatment is successful, the new gene will make a functional protein Contents Background Basic process Types of gene therapy Germ line gene therapy ... edit Background On September 14 at the U.S. National Institutes of Health W. French Anderson , M.D., and his colleagues R. Michael Blaese, M.D., C. Bouzaid, M.D., and Kenneth Culver, M.D., performed the first approved gene therapy procedure on four-year old Ashanthi DeSilva. Born with a rare genetic disease called severe combined immunodeficiency (SCID) , she lacked a healthy immune system, and was vulnerable to every passing germ or infection. Children with this illness usually develop overwhelming infections and rarely survive to adulthood; a common childhood illness like chickenpox is life-threatening. Ashanthi led a cloistered existence avoiding contact with people outside her family, remaining in the sterile environment of her home, and battling frequent illnesses with massive amounts of antibiotics.

3. Gene Therapy At the forefront of medicine, gene therapy brings you the latest research into genetic and cellbased technologies to treat disease. http://www.nature.com/gt/

Jump to main content Jump to navigation nature.com homepage ... Login Search This journal All of nature.com Advanced search Welcome to Gene Therapy At the forefront of medicine, Gene Therapy Free online issue Volume 15, No 3 February 2008 ISSN: 0969-7128 EISSN: 1476-5462 2006 impact factor 15/140 Biotechnology and Applied Microbiology USA Editor: J Glorioso, USA European Editor: N Lemoine, UK *Journal Citation Reports, Thomson 2007 FEATURED ARTICLES ORIGINAL ARTICLE Expression of PAI-1 to prevent abdominal aortic aneurysm ORIGINAL ARTICLE Mechanism of HSV-mediated IL-10 expression in reduction of inflammatory pain ORIGINAL ARTICLE Myostatin antisense-mediated muscle growth in cancer cachexia FREE Current issue table of contents Advance online publication in full NEWS Gene Therapy Stem Cells Special Issue - Out now Stem cell research is booming and much progress has been made within the last few years. This special issue focuses on the fundamental, underappreciated aspects of current stem cell research that have not yet been emphasized within the field. Reviews cover current research with the translational potential for stem cell drug development. Cancer Caused by Gene Therapy Virus A child at Great Ormond Street Hospital has developed Leukaemia after being treated for X-SCID with a gene therapy virus. This is the first case in the UK and ends hopes that the subtly different protocol used in this country prevents incidents of cancer which have already been observed in France.

4. Cancer Gene Therapy Cancer gene therapy is the essential gene therapy resource for cancer researchers and clinicians, keeping readers up to date with the latest developments in http://www.nature.com/cgt/

Jump to main content Jump to navigation nature.com homepage ... Login Search This journal All of nature.com Advanced search Welcome to Cancer Gene Therapy Cancer Gene Therapy Free online issue Volume 15, No 2 February 2008 ISSN: 0929-1903 EISSN: 1476-5500 2006 impact factor 33/131 Genetics and Heredity 37/127 Oncology Editors: R E Sobol K J Scanlon * Journal Citation Reports, Thomson 2007 FEATURED ARTICLES ORIGINAL ARTICLE Anticancer activity of oncolytic adenovirus vector armed with IFN- and ADP is enhanced by pharmacologically controlled expression of TRAIL FREE ORIGINAL ARTICLE Treatment of pulmonary metastatic tumors in mice using lentiviral vector-engineered stem cells FREE ORIGINAL ARTICLE Cancer immunotherapy based on recombinant Salmonella enterica serovar Typhimurium aroA ... Advance online publication in full Research and Reviews Latest research highlights and reviews from the NPG family of journals Lipid signalling in disease Source: Nature Reviews Molecular Cell Biology DNA damage response pathways - this content is FREE Source: Cell Research Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu Source: Nature Main navigation Journal home Advance online publication About AOP Current issue ... Site features NPG resources Immunology and Cell Biology Gene Therapy Nature Biotechnology Nature Genetics ... Nature Reports Stem Cells NPG Journals by Subject Area Chemistry Chemistry Drug discovery Biotechnology Materials ... Earth sciences Life sciences Biotechnology Cancer Development Drug discovery ... Systems biology Physical sciences Physics Materials by A - Z Index Extra navigation

5. ScienceDaily: Gene Therapy News Read all about gene therapy including current medical research on switching therapeutic genes on and off, lightactivated gene therapy and gene silencing. http://www.sciencedaily.com/news/health_medicine/gene_therapy/

Gene Therapy News Thursday, January 24, 2008 Print Email Bookmark Latest News ADD and ADHD Allergy Alzheimer's ... Birth Defects Cancer Brain Tumor Breast Cancer Cancer Colon Cancer ... Skin Cancer Cold and Flu Bird Flu Cold and Flu Influenza Colitis ... Hearing Loss Heart Health Cholesterol Heart Disease Stroke Vioxx ... Urology Medical Topics Accident and Trauma Alternative Medicine Birth Control Bone and Spine ... Vitamins Your Health Children's Health Healthy Aging Infant's Health Men's Health ... Books RSS Adult Cells, Reprogrammed To Embryonic Stem Cell Like State, Treat Sickle-cell Anemia In Mice full story Cancer-resistant Mouse Developed By Adding Tumor-suppressor Gene full story ... Brain Implants Relieve Alzheimer's Damage Browse News Stories 1 to 10 of 557 stories view headlines only Pain Control Fibromyalgia Gene Therapy ... Targeted Gene Therapy Provides Relief For Chronic Pain, Study Shows January 24, 2008 full story Breast Cancer Cancer Genes ... Most Carriers Of Fanconi Anemia Genes Are Not At Higher Risk Of Cancer January 24, 2008 full story Gene Therapy Genes Human Biology ... The RNA Drug Revolution: A New Approach To Gene Therapy January 23, 2008 full story Joint Pain Pain Control Genes ... New Genetic Mutation That Halts The Development Of Lupus Discovered January 21, 2008

6. What Is Gene Therapy? - Genetics Home Reference gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future, this technique may allow doctors to treat a disorder http://ghr.nlm.nih.gov/handbook/therapy/genetherapy

About Site Map Contact Us A service of the Home Conditions Genes Chromosomes ... Resources Handbook Table of Contents Cells and DNA How Genes Work Mutations and Health ... Gene Therapy What is gene therapy? Replacing a mutated gene that causes disease with a healthy copy of the gene. Introducing a new gene into the body to help fight a disease. Although gene therapy is a promising treatment option for a number of diseases (including inherited disorders, some types of cancer, and certain viral infections), the technique remains risky and is still under study to make sure that it will be safe and effective. Gene therapy is currently only being tested for the treatment of diseases that have no other cures. For general information about gene therapy: MedlinePlus from the National Library of Medicine offers a list of links to information about genes and gene therapy The fact sheet Gene Therapy from the U.S. Department of Energy Office of Science offers an overview of this topic. The Centre for Genetics Education provides an introduction to gene therapy , including a discussion of ethical and safety considerations. Additional basic information about gene therapy is available from the Wellcome Trust.

7. Gene Therapy - An Overview A potential approach to the treatment of genetic disorders in man is gene therapy. This is a technique whereby the absent or faulty gene is replaced by a http://www.accessexcellence.org/RC/AB/BA/Gene_Therapy_Overview.html

-Advertisement- Gene Therapy - An Overview BIO. "Biotechnology in Perspective." Washington, D.C.: Biotechnology Industry Organization, 1990. Altered Genes Each of us carries about half a dozen defective genes. We remain blissfully unaware of this fact unless we, or one of our close relatives, are amongst the many millions who suffer from a genetic disease. About one in ten people has, or will develop at some later stage, an inherited genetic disorder, and approximately 2,800 specific conditions are known to be caused by defects (mutations) in just one of the patient's genes. Some single gene disorders are quite common - cystic fibrosis is found in one out of every 2,500 babies born in the Western World - and in total, diseases that can be traced to single gene defects account for about 5% of all admissions to children's hospitals. In the U.S. and Europe, there are exciting new programs to 'map' the entire human genome - all of our genes. This work will enable scientists and doctors to understand the genes that control all diseases to which the human race is prone, and hopefully develop new therapies to treat and predict diseases. Diseases of Genetic Origin Most of us do not suffer any harmful effects from our defective genes because we carry two copies of nearly all genes, one derived from our mother and the other from our father. The only exceptions to this rule are the genes found on the male sex chromosomes. Males have one X and one Y chromosome, the former from the mother and the latter from the father, so each cell has only one copy of the genes on these chromosomes. In the majority of cases, one normal gene is sufficient to avoid all the symptoms of disease. If the potentially harmful gene is recessive, then its normal counterpart will carry out all the tasks assigned to both. Only if we inherit from our parents two copies of the same recessive gene will a disease develop.

8. Gene Therapy: Molecular Bandage? Follow a gene therapy treatment from the lab to the clinic. Challenges in gene therapy Examine some upand-coming techniques in the gene therapy arena. http://learn.genetics.utah.edu/units/genetherapy/index.cfm

Are you a teacher? Sign in Not yet registered? Sign up See our other teacher materials About Us Feedback ... Home Gene Therapy: Molecular Bandage? What is Gene Therapy? The what and why of gene therapy research. Choosing Targets for Gene Therapy See how researchers decide which disorders are appropriate for gene therapy. Gene Delivery: The Key to Gene Therapy Putting therapeutic genes into cells is easier said than done. Find out why. Tools of the Trade Explore the methods for delivering genes into cells. From Research To Trials How long does it take? Follow a gene therapy treatment from the lab to the clinic. Challenges in Gene Therapy Why isn't gene therapy a smashing success? Space Doctor You are the doctor! Design and test gene therapy treatments with ailing aliens. New Approaches to Gene Therapy Examine some up-and-coming techniques in the gene therapy arena. Enhancement: Gene Therapy and Science Fiction Can we use gene therapy techniques to create designer humans? What are Some Issues in Gene Therapy? Consider some important questions in the debate over gene therapy research. Additional Resources Links to current news and in-depth information about gene therapy.

9. Gene Therapy For Cancer: Q & A - National Cancer Institute A fact sheet that discusses research with genetic material in developing cancer therapies, including risks, benefits, and ethical issues. http://www.cancer.gov/cancertopics/factsheet/Therapy/gene

var bSearchBoxBool=false; Reviewed: Page Options Print This Page E-Mail This Document View/Print PDF Search Fact Sheets by Keyword View Fact Sheets by Topic Cancer Type Risk Factors and Possible Causes Prevention Detection/Diagnosis ... Questions about cancer? 1-800-4-CANCER Quick Links Director's Corner Dictionary of Cancer Terms NCI Drug Dictionary Funding Opportunities ... NIH Calendar of Events Gene Therapy for Cancer: Questions and Answers Key Points Gene therapy is an experimental treatment that involves introducing genetic cells to fight or prevent disease (see Question 2 Researchers are studying gene therapy for cancer through a number of different approaches (see Question 3 A gene viruses (see Question 4 The viruses used in gene therapy are altered to make them safe; however, some risks still exist with gene therapy (see Questions 5 and A clinical trial U.S. Food and Drug Administration and the National Institutes of Health Recombinant DNA Advisory Committee (see Questions 9 and The Ethical, Legal, and Social Implications (ELSI) Research Program was established in 1990 to identify, analyze, and address the implications of human genetics research (see Questions 11 and What are genes?

10. Gene Therapy One of the most amazing genetic applications in medicine is gene therapy. Also known as somatic gene therapy and therapeutic gene therapy, this procedure http://library.thinkquest.org/28599/gene_therapy.htm

11. American Society Of Gene Therapy Organization dedicated to promoting gene therapy research through public education, scientific meetings and scientific committees targeting specific http://www.asgt.org/

var BaseURL = "http://www.asgt.org"; var BasePath = ""; Join ASGT Contact Us Site Map Home About Gene Therapy What is Gene Therapy? Gene Therapy Defined Common Gene Therapy Terms Gene Therapy for Diseases Gene Therapy vs. Cell Therapy ... Related Sites of Interest The Society ASGT Board/Committee Rosters ASGT Position Statements ASGT History Molecular Therapy ... Archived Course Materials Members Login Directory Grants/Awards Update Contact Information ... Annual Meeting Patients Sites of Interest About Gene Therapy Media News Releases Primer Guide to ASGT Gene Therapy Experts ASGT Position Statements The American Society of Gene Therapy The American Society of Gene Therapy (ASGT) is a non-profit medical, scientific, and professional organization devoted to the research and development of therapies that involve the introduction of genetic material and/or cells into the body to treat or prevent disease. Gene Therapy News ASGT President Reflects on the Passing of Dr. Judah Folkman Thursday, January 24th, 2008 NHLBI Gene Therapy Resource Program Tuesday, January 22nd, 2008 Regaining Lost Luster: New Developments and Clinical Trials Breathe Life Back into Gene Therapy Wednesday, January 2nd, 2008

12. Gene Therapy I View an animation showing the steps used in retroviral gene therapy at this Molecular Medicine in Action site. Navigate to Other Viruses as Vectors on http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/G/GeneTherapy.html

Index to this page Severe Combined Immunodeficiency (SCID) Treatment Options: Gene Therapy: requirements Target Cells ... Adenovirus Vectors Gene Therapy I Many human diseases are caused by defective genes. A few common examples: Disease Genetic defect hemophilia A absence of clotting factor VIII cystic fibrosis defective chloride channel protein muscular dystrophy defective muscle protein (dystrophin) sickle-cell disease defective beta globin hemophilia B absence of clotting factor IX severe combined immunodeficiency (SCID) any one of several genes fail to make a protein essential for T and B cell function All of these diseases are caused by a defect at a single gene locus . (The inheritance is recessive so both the maternal and paternal copies of the gene must be defective.) Is there any hope of introducing functioning genes into these patients to correct their disorder? Probably. Other diseases, also have a genetic basis, but it appears that several genes must act in concert to produce the disease phenotype . The prospects of gene therapy in these cases seems far more remote. Case study: severe combined immunodeficiency (SCID) SCID is a disease in which the patient has neither cell-mediated immune responses nor is able to make antibodies It is a disease of young children because, until recently, the absence of an immune system left them prey to infections that ultimately killed them.

13. BBC NEWS | Health | Gene Therapy Implants For Tendons Freezedried implants are being developed which may help repair injured and difficult-to-treat tendons. http://news.bbc.co.uk/1/hi/health/7176360.stm

@import "/css/screen/shared/styles.css?v2"; @import '/css/screen/shared/toolbar_ukfs.css?v1'; @import "/css/screen/nol/styles.css?v2"; @import "/css/screen/nol/furniture.css?v1"; @import "/css/screen/nol/promo.css"; @import "/css/screen/nol/programmes.css?v2"; @import "/css/screen/nol/business.css"; @import "/css/screen/nol/election07_index.css"; @import "/css/screen/nol/ukfs.css"; Accessibility Links Skip to content Skip to bbc.co.uk navigation Skip to search Access keys help ... bbc.co.uk bbc.co.uk Navigation Search Home TV Radio Talk ... Accessibility help BBC News 24 News services Your news when you want it News Front Page World UK England ... Special Reports RELATED BBC SITES SPORT WEATHER CBBC NEWSROUND ON THIS DAY ... EDITORS' BLOG Last Updated: Saturday, 12 January 2008, 00:02 GMT E-mail this to a friend Printable version Gene therapy implants for tendons Tendon injuries can be difficult to treat Freeze-dried implants loaded with gene therapy solution are being developed which may help repair injured and difficult-to-treat tendons. Early trials in the US suggest the implants could accelerate healing, and help restore a wide range of movement.

14. Gene Therapy In the 1980s scientists learned how to insert healthy copies of defective genes into a cell s genetic material. Since then, they ve looked forward to the http://www.americanheart.org/presenter.jhtml?identifier=4566

15. American Scientist Online - Gene Therapy AmericanScientist.org An archive of articles covering original scientific research into astronomy, medical science, anthropology, ecology, technology, http://www.amsci.org/amsci/articles/99articles/Kmiec.html

Home Current Issue Archives Bookshelf ... Subscribe In This Section Search Book Reviews by Issue Issue Index Topical Index ... Classics Site Search Advanced Search Visitor Login Username Password Help with login Forgot your password? Change your username see full issue: May-June 1999 Volume: Number: Page: DOI: Gene Therapy Investigators have been searching for ways to add corrective genes to cells harboring defective genes. A better strategy might be to correct the defects Eric B. Kmiec It has been the hope of biomedical researchers to find ways to fix the genes that cause disease. Over a decade ago, when researchers at MIT realized that viruses could be modified to carry corrective genes into cells, gene therapy seemed to be an eventuality. But to date, no one has found a way to reliably control the therapeutic genes to make them clinically useful. Our author surveys the history of this field and gives us a peek at the future of gene therapy, where the emphasis may be less on replacing defective genes and more on correcting them. Go to Article Of Possible Interest Book Review: Analytical Tools for Evolutionary Processes Feature Article: Gene Therapy for Pain Feature Article: Ancient DNA Feature Article: Human Embryonic Stem-Cell Research: Science and Ethics Feature Article: Early Canid Domestication: The Farm-Fox Experiment Related Sigma Xi Links

16. Gene Therapy And Children gene therapy carries the excitement of a cureall for many diseases, the controversy surrounding the altering of human imperfection, and the promise of a http://kidshealth.com/parent/system/medical/gene_therapy.html

var fo = new FlashObject("/image/parentnav/intheNEWS_button.swf", "pl1", "153", "43", "5", ""); fo.addParam("QUALITY", "High"); fo.write("parent_left_flash_1"); var fo = new FlashObject("/updates/P_squarebanner.swf", "pl2", "153", "126", "5", ""); fo.addParam("QUALITY", "High"); fo.write("parent_left_flash_2"); var fo = new FlashObject("/image/parentnav/whatsNew_squarebanner.swf", "pl3", "153", "108", "5", ""); fo.addParam("QUALITY", "High"); fo.write("parent_left_flash_3"); var fo = new FlashObject("/image/parentnav/temp_banner.swf", "pl4", "153", "108", "5", ""); fo.addParam("QUALITY", "High"); fo.write("parent_left_flash_4"); KidsHealth Parents Gene therapy carries the excitement of a cure-all for a host of diseases, the controversy surrounding the altering of human genes, and the promise of a type of medical treatment most of us would never imagine possible. With its potential to eliminate and prevent hereditary diseases such as cystic fibrosis and hemophilia and its use as a possible cure for heart disease, AIDS , and cancer , gene therapy is a potential medical miracle-worker.

17. MedlinePlus: Genes And Gene Therapy gene therapy is an experimental technique that uses genes to treat or prevent disease. The most common form of gene therapy involves inserting a normal gene http://www.nlm.nih.gov/medlineplus/genesandgenetherapy.html

imageNames = false; @import url(http://www.nlm.nih.gov/medlineplus/images/advanced.css); @import url(http://www.nlm.nih.gov/medlineplus/images/header.css); @import url(http://www.nlm.nih.gov/medlineplus/images/menubutton.css); Skip navigation @import url("http://www.nlm.nih.gov/medlineplus/images/consumer_health_20.css"); Other Health Topics: A B C D ... List of All Topics Related Topics Genetic Disorders Genetic Testing Genetics/Birth Defects Go Local Services and providers for Genes and Gene Therapy in the U.S. Select Location AL - Alabama AR - Arkansas AZ - Arizona AZ - Tribal Connections Four Corners CO - Tribal Connections Four Corners DE - Delaware GA - Georgia IL - Illinois IN - Indiana MA - Massachusetts MD - Maryland MI - Michigan MN - Minnesota NC - North Carolina NE - Nebraska NM - New Mexico NM - Tribal Connections Four Corners NV - Nevada OH - Ohio - Southeast SC - South Carolina TX - East Texas TX - South Texas TX - Texas Gulf Coast UT - Tribal Connections Four Corners UT - Utah VT - Vermont WY - Wyoming Select from map National Institutes of Health The primary NIH organization for research on Genes and Gene Therapy is the National Human Genome Research Institute Genes and Gene Therapy Genes are the building blocks of inheritance. Passed from parent to child, they contain instructions for making proteins. If genes don't produce the right proteins or produce them correctly, a child can have a

18. Gene Therapy -- Kay Et Al. 94 (24): 12744 -- Proceedings Of The National Academy In recent years, there have been a number of technological breakthroughs that have allowed for clinical trials in gene therapy to be initiated. http://www.pnas.org/cgi/content/full/94/24/12744

This Article Abstract Full Text (PDF) Alert me when this article is cited ... Citation Map Services Email this article to a colleague Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed ... Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via ISI Web of Science (102) Citing Articles via Google Scholar Google Scholar Articles by Kay, M. A. Articles by Hoogerbrugge, P. M. Search for Related Content PubMed PubMed Citation Articles by Kay, M. A. Articles by Hoogerbrugge, P. M. Social Bookmarking What's this? Previous Article Table of Contents Next Article Proc. Natl. Acad. Sci. USA Vol. 94, pp. 12744-12746, November 1997 From the Academy This paper is a summary of a session presented at the third annual German-American Frontiers of Science symposium, held June 20-22, 1997 at the Kardinal Wendel Haus in Munich, Germany. Gene therapy Mark A. Kay

19. Gene Therapy Clinical Trials Worldwide Comprehensive source of information on worldwide gene therapy clinical trials compiled by The Journal of Gene Medicine. http://www.wiley.co.uk/genetherapy/clinical/

20. Human Gene Therapy Human gene therapy A rapidpublication peer-reviewed journal covering all aspects of human gene therapy. Publishes scientific papers on original http://www.liebertpub.com/hum

The Leading Publisher in Biotechnology view cart Home About Us Publications ... Contact Us Mary Ann Liebert, Inc., The Leading Publisher in Biotechnology General Information View/Search Full Text Read a Free Issue Tables of Contents Editorial Board ... Advertising Information addthis_url = location.href; addthis_title = document.title; addthis_pub = 'jcruz'; Human Gene Therapy ISSN 1043-0342 - Published Monthly Subscribe Full-text of the current issue available FREE online. Due to the dynamic nature of this field, the journal has a rapid online publication policy. All papers are published online within 3-4 weeks of acceptance, and will appear at a later date in the print journal. Don't miss this month's Editorial - A Call to Action New “Open Option” for Human Gene Therapy A rapid-publication peer-reviewed journal covering all aspects of human gene therapy. Publishes scientific papers on original investigations into the transfer and expression of genes in mammals, including humans. Improvements in vector development, delivery systems, and animal models, particularly in the areas of cancer, heart disease, viral disease, genetic disease, and neurological disease, are covered. Includes ethical/legal/regulatory papers related directly to the area of gene transfer into humans. Impact factor - 2006 - ISI Journal Citation Reports ® Subscribe Indexed/abstracted in: MEDLINE; Current Contents/Life Sciences; EMBASE/Excerpta Medica; Cambridge Scientific Abstracts; Science Citation Index-Expanded; Science Citation Index; BIOSIS Previews; Biotechnology Citation Index; Biological Abstracts; EMBiology; Scopus

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