1. Susumu Tonegawa - Autobiography Susumu Tonegawa Autobiography. I was born in Nagoya, Japan on September 6th, 1939, the second of three sons. I have also a younger sister. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

2. Medicine 1987 Susumu Tonegawa Autobiography Nobel Lecture Banquet Speech Other Resources 1986 1988. The 1987 Prize in Physics Chemistry http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. Tonegawa Susumu tonegawa susumu, 1987. Copyright Rick Friedman/Black Star Tonegawa receiveda BS degree from Kyoto University in 1963 and earned a Ph.D. in biology from http://www.britannica.com/nobel/micro/598_42.html

Tonegawa Susumu Tonegawa Susumu, 1987 (b. Sept. 5, 1939, Nagoya, Japan), Japanese molecular biologist and immunologist who was awarded the Nobel Prize for Physiology or Medicine in 1987 for his fundamental discoveries concerning the body's production of antibodies Tonegawa received a B.S. degree from Kyoto University in 1963 and earned a Ph.D. in biology from the University of California, San Diego in 1969. He was a member of the Basel Institute for Immunology in Switzerland from 1971 to 1981 and taught biology at the Massachusetts Institute of Technology from 1981. Tonegawa's research explained how the immune system can produce a vast diversity of antibodies, each of which reacts with and counteracts the effects of a separate antigen (a foreign molecule or microbe). Prior to Tonegawa's work it was not known how the B lymphocytes (the cells that produce antibodies) could with their limited number of genes produce the millions of differently structured antibodies that are specific to a comparable diversity of antigens. In the 1970s Tonegawa proved in a series of experiments that approximately 1,000 pieces of genetic material in the antibody-manufacturing portion of the B lymphocyte can be shuffled or recombined into different sequences, the resulting variations enabling the production of as many as one billion different types of antibodies, each specific to a different antigen. A fundamental mechanism in the immune system was thus revealed.

4. Susumu Tonegawa Susumu Tonegawa uses genetically engineered mice to investigate neural development and the molecular, cellular, and neuronal ensemble mechanisms http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Tonegawa Susumu --  Encyclopædia Britannica tonegawa susumu Japanese molecular biologist who was awarded the Nobel Prize forPhysiology or Medicine in 1987 for his discovery of the genetic mechanisms http://www.britannica.com/eb/article-9072862?hook=228673

6. Susumu Tonegawa Winner Of The 1987 Nobel Prize In Medicine Susumu Tonegawa, a Nobel Prize Laureate in Physiology and Medicine, at the Nobel Prize Internet Archive. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. MIT Department Of Biology Susumu Tonegawa Home Faculty and Areas of Research Susumu Tonegawa, 2004 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Susumu Tonegawa: Definition And Much More From Answers.com To·ne·ga·wa Su·su·mu ( tône gä-wä su-su mu ) , Born 1939. Japanese molecularbiologist. He won a 1987 Nobel Prize for discovering how certain. http://www.answers.com/topic/susumu-tonegawa

showHide_TellMeAbout2('false'); Business Entertainment Games Health ... More... On this page: Dictionary Encyclopedia Medical WordNet Wikipedia Mentioned In Or search: - The Web - Images - News - Blogs - Shopping Susumu Tonegawa Dictionary To·ne·ga·wa Su·su·mu t´-nĕ g¤-w¤ sÅ«-sÅ« mÅ« , Born 1939. Japanese molecular biologist. He won a 1987 Nobel Prize for discovering how certain cells of the immune system can genetically rearrange themselves to produce diverse antibodies. Encyclopedia Tonegawa, Susumu, 1939–, Japanese molecular biologist, Ph.D. Univ. of California at San Diego, 1969. A member of the Basel Institute for Immunology in Switzerland (1971–81), he became a professor of biology at the Massachusetts Institute of Technology in 1981. Tonegawa discovered the general principle that underlies the body's ability to produce millions of antibodies from cells that contain a limited amount of genetic material. For his discovery, He was awarded the 1987 Nobel Prize in Physiology or Medicine. Medical To·ne·ga·wa Su·su·mu t´-nĕ g¤-w¤ sÅ«-sÅ« mÅ« ), Born 1939.

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10. Susumu Tonegawa - Wikipedia, The Free Encyclopedia Susumu Tonegawa (? ? tonegawa susumu, born September 6, 1939) is a Japanesescientist who won the Nobel Prize for Physiology or Medicine in 1987 for http://en.wikipedia.org/wiki/Susumu_Tonegawa

Susumu Tonegawa From Wikipedia, the free encyclopedia. Susumu Tonegawa Tonegawa Susumu , born September 6 ) is a Japanese scientist who won the Nobel Prize for Physiology or Medicine in for "his discovery of the genetic principle for generation of antibody diversity." Although he won the Nobel Prize for his work in immunology , Tonegawa is a molecular biologist by training. In his later years, he has turned his attention to the molecular and cellular basis of memory formation. To achieve the diversity of antibodies needed to protect against any type of antigen, the immune system would require millions of genes coding for different antibodies, if each antibody was encoded by one gene. Instead, as Tonegawa showed in a landmark series of experiments beginning in , genetic material can rearrange itself to form the vast array of available antibodies. Comparing the DNA of B cells (a type of white blood cells ) in embryonic and adult mice , he observed that genes in the B cells of the older mice are moved around, recombined, and deleted to form the diversity of the variable region of antibodies. Tonegawa was born in Nagoya, Japan

11. Biografia De Tonegawa, Susumu Las figuras clave de la historia. Reportajes. Los protagonistas de la actualidad. Tonegawa, Susumu (1939 ) Inmun logo japon s, n. en Nagoya. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

12. Susumu Tonegawa Susumu Tonegawa (1939 ) Bi logo japon s nascido em Nagoya, pesquisador do Massachusetts Institute of Technology (MIT), Cambridge, MA, U.S.A http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

13. Biochemistry Page 1. Index To Biographical Entries. The Columbia Pedersen, Charles John. Snell, George Davis. Tonegawa, Susumu. Vane, John Robert. Wittig, Georg. The Columbia Encyclopedia, Sixth Edition. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

14. Tonegawa Susumu. The American Heritage® Dictionary Of The English Language: Fou tonegawa susumu. The American Heritage® Dictionary of the English Language FourthEdition. 2000. http://www.bartleby.com/61/8/T0260800.html

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15. MSN Encarta - Tonegawa Susumu tonegawa susumu, born in 1939, Japanese molecular biologist at the Massachusetts Other Features from Encarta. Search Encarta for tonegawa susumu http://encarta.msn.com/encyclopedia_761566682/Tonegawa_Susumu.html

MSN Home My MSN Hotmail Shopping ... Sign In Web Search: Encarta Subscriber Sign In Help Home ... Upgrade your Encarta Experience Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Tonegawa Susumu Tonegawa Susumu , born in 1939, Japanese molecular biologist at the Massachusetts Institute of Technology (MIT) and sole winner of the 1987 Nobel Prize... Multimedia Selected Web Links Susumu Tonegawa [Nobel Foundation] 1 item Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Tonegawa Susumu from Other Features from Encarta Search Encarta for Tonegawa Susumu © 2005 Microsoft MSN Privacy Legal Advertise Feedback ... Help

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17. Tonegawa Susumu - YourDictionary.com - American Heritage Dictionary Search Mamma.com for tonegawa susumu . TYPE IN YOUR WORD CLICK GO! Search.Normal, Definitions, Short defs. (Pronunciation Key) http://www.yourdictionary.com/ahd/t/t0260800.html

Search Mamma.com for "Tonegawa Susumu" Search: Normal Definitions Short defs (Pronunciation Key) To·ne·ga·wa Su·su·mu Listen: tô-n gä-wä s -s m , Born 1939. Japanese molecular biologist. He won a 1987 Nobel Prize for discovering how certain cells of the immune system can genetically rearrange themselves to produce diverse antibodies. Back to Search Back The American Heritage Dictionary of the English Language, Fourth Edition

18. MIT Department Of Biology: Susumu Tonegawa Susumu Tonegawa, MIT Department of Biology Search Main Menu Contact Us Home Faculty and Areas of Research Susumu Tonegawa, 2004. Susumu Tonegawa http://web.mit.edu/biology/www/facultyareas/facresearch/tonegawa.shtml

Home Faculty and Areas of Research Susumu Tonegawa, 2004 Susumu Tonegawa Picower Professor of Biology and Neuroscience and Investigator, Howard Hughes Medical Institute Director, Picower Center for Learning and Memory Ph.D. 1968, University of California, San Diego Room E17-353 Phone: (617) 253-6459 Email: tonegawa@mit.edu Overview Research Summary Memory acquisition. Using the Cre/loxP system, we previously targeted a knockout of the obligatory N-methyl-D-aspartate (NMDA) receptor (NR) subunit, NR1, to the CA1 pyramidal cells of young adult mice. (Tsien et al. , 1996b) These mice displayed impairments in the Schaffer collateral (SC) CA1 long-term potentiation (LTP) and in spatial learning in the standard Morris water maze task. That this mutant mouse is defective in the acquisition rather than the retrieval of the memory was suggested by its inability to form normal memory representations as CA1 place cells (McHugh et al.

19. The Picower Institute: Faculty + Research: Susumu Tonegawa Susumu Tonegawa. The Picower Center for Learning and Memory at MIT The mainresearch interest of Professor Susumu Tonegawa s lab is to understand the http://web.mit.edu/picowercenter/faculty/tonegawa.html

Susumu Tonegawa Learning and memory are vital for day-to-day living, from finding our way home to playing tennis to making a cohesive speech. Many of us have personally witnessed the devastating consequences of memory disorders such as Alzheimer's and Parkinson's diseases. The main research interest of Professor Susumu Tonegawa's lab is to understand the molecular, cellular, neuronal circuitry, and neural systems mechanisms underlying learning and memory and associated cognitive functions. Our main approach is to generate conditionally engineered mouse strains in which a specific gene or its protein function is eliminated in a spatially restricted and/or temporally controlled manner in the brain; we then analyze these mice with a series of techniques designed to detect abnormal phenotypes at different levels of complexity from molecules and cells to neuronal circuitries and brain systems to behavior of a whole living animal. These techniques include those of molecular and cell biology, histology and histochemistry, confocal and two-photon laser microscopy, in vitro and in vivo electrophysiology, and behavioral studies. Our goal is to identify a correlate at a particular level of complexity of an event occurring at another level, and eventually establish their cause-consequence relationship from molecules all the way to behavior.

20. Tonegawa Susumu - BlueRider.com tonegawa susumu listen domain availability. Dictionary and Thesaurus entriesfor. tonegawa susumu. Your search results tonegawa susumu n http://tonegawa_susumu.bluerider.com/wordsearch/tonegawa_susumu

Enter a word or phrase Random Word walk-up Other Services Word Index Contact Us ... Links tonegawa susumu listen domain availability Dictionary and Thesaurus entries for: tonegawa susumu Your search results... Web bluerider.com tonegawa susumu [n] Japanese molecular biologist noted for his studies of how the immune system produces antibodies (born in 1939) Synonyms : See Also: Your Search History clear Enter a word or phrase Terms of Service Linux Man Pages Geographic Information ccTLD Information

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