21. Temin, Howard Martin temin, howard martin. (b. Dec. 10, 1934, Philadelphia, Pa., USd. Feb. 9, 1994,Madison, Wis.), American virologist who in 1975 shared the Nobel Prize for http://www.britannica.com/nobel/micro/585_99.html

Temin, Howard Martin (b. Dec. 10, 1934, Philadelphia, Pa., U.S.d. Feb. 9, 1994, Madison, Wis.), American virologist who in 1975 shared the Nobel Prize for Physiology or Medicine with his former professor Renato Dulbecco and another of Dulbecco's students, David Baltimore , for his codiscovery of the enzyme reverse transcriptase. While working toward his Ph.D. under Dulbecco at the California Institute of Technology, Temin began investigating how the Rous sarcoma virus causes animal cancers. One puzzling observation was that the virus, the essential component of which is ribonucleic acid (RNA), could not infect the cell if the synthesis of deoxyribonucleic acid (DNA) was stopped. Temin proposed in 1964 that the virus somehow translated its RNA into DNA, which then redirected the reproductive activity of the cell, transforming it into a cancer cell. The cell would reproduce this DNA along with its own DNA, producing more cancer cells. Skeptics pointed out that Temin's suggestion contradicted the contemporary tenet of molecular biology: that genetic information always passed from DNA to RNA, rather than the reverse. But in 1970 both Temin and Baltimore proved Temin's hypothesis correct. They identified an enzyme (reverse transcriptase) in the virus that synthesizes DNA that contains the information in the viral RNA. Temin obtained his Ph.D. in 1959, and after spending another year with Dulbecco, he joined the faculty of the University of Wisconsin in Madison, where he taught and conducted research until his death.

22. Britannica Student Encyclopedia temin, howard martin American virologist who in 1975 shared the Nobel Prize forPhysiology or Medicine with his former professor Renato Dulbecco and another http://www.britannica.com/ebi/print_toc?tocId=9316935

23. Temin, Howard Martin. The Columbia Encyclopedia, Sixth Edition. 2001-05 temin, howard martin. The Columbia Encyclopedia, Sixth Edition. 200105. http://www.bartleby.com/65/te/Temin-Ho.html

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24. Howard Martin Temin temin, howard martin, 1934–94, American virologist, b. Philadelphia, Ph.D.California Institute of Technology, 1959. A professor at the Univ. of Wisconsin http://www.factmonster.com/ce6/people/A0848112.html

Home U.S. People Word Wise ... Homework Center Fact Monster Favorites Hurricane Katrina Children as Authors Children Inventors The Doctor's In ... 2006 TFK Almanac Reference Desk Atlas Almanacs Dictionary Encyclopedia ... Encyclopedia Temin, Howard Martin Temin, Howard Martin, , American virologist, b. Philadelphia, Ph.D. California Institute of Technology, 1959. A professor at the Univ. of Wisconsin in Madison, Temin began his cancer research while still a student, working with his professor Renato Dulbecco and fellow student David Baltimore . In 1970 they experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia, Page Tools: Cite Print See more Encyclopedia articles on: Cell Biology: Biographies AD AD AD ADS Business Cards Link to Fact Monster Add Fact Monster search ... Privacy Brought to you by: Information Please

25. Renato Dulbecco howard martin temin temin, howard martin, 1934–94, American virologist, b.Philadelphia, Ph.D. California David Baltimore - Baltimore, David , 1938–, http://www.factmonster.com/ce6/people/A0816281.html

Home U.S. People Word Wise ... Homework Center Fact Monster Favorites Hurricane Katrina Children as Authors Children Inventors The Doctor's In ... 2006 TFK Almanac Reference Desk Atlas Almanacs Dictionary Encyclopedia ... Encyclopedia Dulbecco, Renato [r u Pronunciation Key Dulbecco, Renato Temin and David Baltimore , experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia, Page Tools: Cite Print More on Renato Dulbecco from Fact Monster: Howard Martin Temin David Baltimore Information Please: 1975 - Pol Pot and Khmer Rouge take over Cambodia (April). The city of Saigon is surrendered and remaining ... Nobel Prizes (table) - Encyclopedia Nobel Prizes Year Peace Chemistry Physics Physiology or Medicine Literature 1901 J. H. ... See more Encyclopedia articles on: Medicine: Biographies AD AD AD ADS Business Cards Link to Fact Monster Add Fact Monster search ... Privacy Brought to you by: Information Please

26. Howard Martin Temin temin, howard martin (The Columbia Encyclopedia, Sixth Edition). temin, howardmartin (19341994) (The Hutchinson Encyclopedia). temin, howard martin (1934- http://www.infoplease.com/ce6/people/A0848112.html

in All Infoplease Almanacs Biographies Dictionary Encyclopedia Daily Almanac for Sep 15, 2005 Skip Navigation Home Almanacs ... Word of the Day Editor's Favorites Back to School Hurricane Katrina Daylight Saving Time Ramadan ... Mississippi Infoplease Tools Periodic Table Conversion Tool Perpetual Calendar Year by Year ... Site Map College Center Scholarship Search College Resources Career Center Job Search Post Your Resume Continuing Ed. more . . . Search: Infoplease Info search tips Search: Biographies Bio search tips google_ad_client = 'pub-1894504138907931'; google_ad_width = 120; google_ad_height = 240; google_ad_format = '120x240_as'; google_ad_type = 'text'; google_ad_channel =''; google_color_border = ['336699','B4D0DC','DFF2FD','B0E0E6']; google_color_bg = ['FFFFFF','ECF8FF','DFF2FD','FFFFFF']; google_color_link = ['0000FF','0000CC','0000CC','000000']; google_color_url = ['008000','008000','008000','336699']; google_color_text = ['000000','6F6F6F','000000','333333']; Encyclopedia Temin, Howard Martin Temin, Howard Martin, , American virologist, b. Philadelphia, Ph.D. California Institute of Technology, 1959. A professor at the Univ. of Wisconsin in Madison, Temin began his cancer research while still a student, working with his professor Renato Dulbecco and fellow student David Baltimore . In 1970 they experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. The Columbia Electronic Encyclopedia

27. Renato Dulbecco howard martin temin temin, howard martin, 1934–94, American virologist, b. temin, howard martin (The Columbia Encyclopedia, Sixth Edition) http://www.infoplease.com/ce6/people/A0816281.html

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28. MSN Encarta - Temin, Howard Martin temin, howard martin (19341994), American virologist and winner of the 1975Nobel Prize in physiology or medicine, which he shared with American http://encarta.msn.com/encyclopedia_761582646/Temin_Howard_Martin.html

MSN Home My MSN Hotmail Shopping ... Sign In Web Search: Encarta Subscriber Sign In Help Home ... Upgrade your Encarta Experience Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Temin, Howard Martin Temin, Howard Martin (1934-1994), American virologist and winner of the 1975 Nobel Prize in physiology or medicine, which he shared with American... Related Items 1975 Nobel Prize recipients corecipients of the Nobel Prize 6 items Multimedia Selected Web Links Howard M. Temin [Nobel Foundation] 1 item Sidebars SCIENTIFIC DISCOVERIES RNA-Directed DNA Synthesis Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles

29. AllRefer.com - Howard Martin Temin (Cell Biology, Biography) - Encyclopedia AllRefer.com reference and encyclopedia resource provides complete informationon howard martin temin, Cell Biology, Biographies. http://reference.allrefer.com/encyclopedia/T/Temin-Ho.html

AllRefer Channels :: Health Yellow Pages Reference Weather September 15, 2005 Medicine People Places History ... Maps Web AllRefer.com You are here : AllRefer.com Reference Encyclopedia Cell Biology, Biographies ... Howard Martin Temin By Alphabet : Encyclopedia A-Z T Howard Martin Temin, Cell Biology, Biographies Related Category: Cell Biology, Biographies Howard Martin Temin Dulbecco and fellow student David Baltimore . In 1970 they experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. Topics that might be of interest to you: David Baltimore Renato Dulbecco Related Categories: Medicine Biographies People Science and Technology ... Biographies More articles from AllRefer Reference on Howard Martin Temin SITE MAPS Encyclopedia US Gazetteer: US States A-C US States D-H US States I-L US States M ... Countries A-Z Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. About Us Contact Us Privacy Links Directory ... Link to AllRefer.com

30. AllRefer.com - Renato Dulbecco (Medicine, Biography) - Encyclopedia In 1970, Dulbecco and two of his students, howard M. temin and David Baltimore,experimentally verified temin s David Baltimore • howard martin temin http://reference.allrefer.com/encyclopedia/D/Dulbecco.html

AllRefer Channels :: Health Yellow Pages Reference Weather September 15, 2005 Medicine People Places History ... Maps Web AllRefer.com You are here : AllRefer.com Reference Encyclopedia Medicine, Biographies ... Renato Dulbecco By Alphabet : Encyclopedia A-Z D Renato Dulbecco, Medicine, Biographies Related Category: Medicine, Biographies Renato Dulbecco [r u O O Pronunciation Key Temin and David Baltimore , experimentally verified Temin's hypothesis that cancer cells affect genetic material. For this discovery the three were awarded the 1975 Nobel Prize in Physiology or Medicine. Topics that might be of interest to you: David Baltimore Howard Martin Temin Related Categories: Medicine Biographies People Medicine More articles from AllRefer Reference on Renato Dulbecco SITE MAPS Encyclopedia US Gazetteer: US States A-C US States D-H US States I-L US States M ... Countries A-Z Content on this web site is provided for informational purposes only. We accept no responsibility for any loss, injury or inconvenience sustained by any person resulting from information published on this site. We encourage you to verify any critical information with the relevant authorities. About Us Contact Us Privacy Links Directory ... Link to AllRefer.com

31. Temin, Howard Martin temin, howard martin (19341994) temin was born in Philadelphia and educatedat Swarthmore College, Pennsylvania, and the California Institute of http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/T/Temin/1.html

Temin, Howard Martin US virologist concerned with cancer research. For his work on the genetic inheritance of viral elements he shared the 1975 Nobel Prize for Physiology or Medicine with David Baltimore (1938- ) and Renato Dulbecco Temin was born in Philadelphia and educated at Swarthmore College, Pennsylvania, and the California Institute of Technology. From 1960 he worked at the University of Wisconsin, becoming professor 1969. Temin's prizewinning research was on a virus that has a mechanism which incorporates its material into mammalian genes. He discovered that beneficial mutations outside the germ line are naturally selected and that the mechanism adds genetic information from outside into the germ line.

32. Howard Martin Temin – Co-discoverer Of Reverse Biological Information Flow - Re howard martin temin – Codiscoverer of Reverse Biological Information Flow In a series of elegant experiments, temin and coworkers showed that at least http://www.ias.ac.in/resonance/July2002/July2002ArticleInABox.html

Now Searchable! journal of science education Search About Resonance Editorial Board ... Back Issues This Year January February March April May June Article in a Box Howard Martin Temin – Co-discoverer of Reverse Biological Information Flow S Mahadevan One of the first observations of Temin, working under the guidance of Harry Rubin, a post doc in Dulbecco's lab, was that when RSV was added to a sparse layer of chicken embryonic cells, infected centers showed up as foci, the cell-culture equivalents of tumours. Even today, this is an important assay for the tumerogenic potential of a virus. Temin also found that the morphology of the foci were different when genetic variants of the virus was used, leading to the important conclusion that transformation is the result of action by genes carried by the virus. Subsequent studies by others established that these are cellular genes `hijacked' by the virus, whose function has been modified. Thus it was realized that modification of normal cellular genes can lead to cancer. the viral RNA genome is used as a template to make a DNA copy that is integrated into the host genome. The DNA provirus is then used as a template that is transcribed to give the viral RNA copies.

33. Temin - YourDictionary.com - American Heritage Dictionary Search Mamma.com for temin . TYPE IN YOUR WORD CLICK GO! Search Tem·inListen t m n , howard martin 19341994. American oncologist. http://www.yourdictionary.com/ahd/t/t0096800.html

Search Mamma.com for "Temin" Search: Normal Definitions Short defs (Pronunciation Key) Tem·in Listen: t m n Howard Martin American oncologist. He shared a 1975 Nobel Prize for research on the interaction of tumor viruses and genetic material. Back to Search Back The American Heritage Dictionary of the English Language, Fourth Edition

34. Caltech Nobel Site howard martin temin WILLIAM NUNN LIPSCOMB, JR. ROBERT WOODROW WILSON howard martin temin (1934–1994) howard temin shared the 1975 Nobel Prize in http://pr.caltech.edu/events/caltech_nobel/home2.html

Caltech Nobel Recipients [ List 1 List 2 DAVID BALTIMORE RENATO DULBECCO ... HUGH DAVID POLITZER DAVID BALTIMORE (b. 1938) RENATO DULBECCO (b. 1914) Howard Temin shared the 1975 Nobel Prize in Physiology or Medicine with Renato Dulbecco and David Baltimore for their joint discovery of the enzyme reverse transcriptase. Identification of this enzyme helped explain how certain viruses transform the cells they infect into cancer cells. WILLIAM NUNN LIPSCOMB, JR. (b. 1919) ROBERT WOODROW WILSON (b. 1936) Roger Sperry was a corecipient (with David Hubel and Torsten Wiesel) of the 1981 Nobel Prize in Physiology or Medicine for their research on the workings of the brain. Sperry was particularly recognized for discovering that each brain hemisphere controls different kinds of functions. KENNETH GEDDES WILSON (b. 1936 Kenneth Wilson was awarded the 1982 Nobel Prize in Physics for his work to construct improved theories about the transformations of matter called continuous, or second-order, phase transitions. His research led to a very general and effective mathematical strategy for understanding how complex microscopic behavior underlies gross macroscopic effects. Willy Fowler shared (with S. Chandrasekhar) the 1983 Nobel Prize in Physics for his work on nucleosynthesis, the process whereby the nuclei of lighter chemical elements fuse to create heavier ones. In groundbreaking work in the late 1950s, he and his colleagues demonstrated that, starting only with the hydrogen and helium produced in the Big Bang, all the elements from carbon to uranium could be produced by the nuclear processes in stars.

35. [ISI Highly Cited Researchers Version 1.1] Highly Cited Researcher temin, howard martin ISI Assigned Category,Microbiology. ISI Indexed Name, temin HM temin. ISI Notes, Deceased http://hcr3.isiknowledge.com/author.cgi?&id=1966

36. [ISI Highly Cited Researchers Version 1.1] Highly Cited Researcher temin, howard martin Pathak, VK, temin, HM BROADSPECTRUMOF INVIVO FORWARD MUTATIONS, HYPERMUTATIONS, AND MUTATIONAL HOTSPOTS http://hcr3.isiknowledge.com/formViewCharacteristic.cgi?table=Publication&link1=

37. Articles - Howard Martin Temin under the terms of the GNU Free Documentation License Source Original textfrom the article in Wikipedia, The Free Encyclopedia howard martin temin. http://www.1-electric.com/articles/Howard_Temin

Home Electric Scooters Wheelchairs Lifts Howard Martin Temin December 10 February 9 ) was a U.S. geneticist . He discovered reverse transcriptase University of Wisconsin-Madison . He won a Nobel Prize in Physiology or Medicine in for describing how tumor viruses act on the genetical material of the cell through reverse transcriptase. This upset the widely held belief at the time of the "Central Dogma" of molecular biology posited by Nobel laureate Francis Crick , one of the co-discoverers of the structure of DNA (along with James Watson and Rosalind Franklin ). Crick, along with most other molecular biologists of the day, believed genetic information to flow exclusively from DNA to RNA to protein . Temin showed that certain tumor viruses carried the enzymatic ability to reverse the flow of information from RNA back to DNA using reverse transcriptase. This phenomenon was also independently studied by David Baltimore , with whom Temin shared the Nobel Prize. The discovery of reverse transcriptase is one of the most important of the modern era of medicine, as reverse transcriptase is the central enzyme in several widespread human diseases, such as HIV , the virus that causes AIDS , and Hepatitis B . Reverse transcriptase is also an important component of several important techniques in molecular biology and diagnostic medicine, such as the polymerase chain reaction (PCR).

38. International: Italiano: Salute: Medicina: Medici E Ricercatori: Temin, Howard M Translate this page Salute Medicina Medici e Ricercatori temin, howard martin - Open Site. howard M. temin. Data di nascita 10 dicembre 1934 Data di morte 1994 http://open-site.org/International/Italiano/Salute/Medicina/Medici_e_Ricercatori

Open Site The Open Encyclopedia Project Pagina principale Aggiungi Contenuti Diventa Editore In tutta la Directory Solo in Medici_e_Ricercatori/Temin,_Howard_Martin Top International Italiano Salute ... Medici e Ricercatori : Temin, Howard Martin E’ stato insignito del premio Nobel per la medicina, (per le scoperte concernenti l'interazione fra i virus del tumore ed il materiale genetico della cellula), nell'anno 1975. Howard M. Temin Data di nascita : 10 dicembre 1934 Data di morte Genere Attivit  principale presso: University of Wisconsin, Madison, WI, USA Opere importanti : Editorialista per le seguenti riviste scientifiche: Journal of Cellular Physiology, Journal of Virology, Proceedings of the National Academy of Sciences U.S.A. Luogo di nascita : Philadelphia, Pennsylvania - USA Nazionalit  : Statunitense Vedi anche: International: Italiano: Societ : Strutture Sociali: Persone: Biografie: Premio Nobel Questa Categoria ha bisogno di un Editore - Richiedila Open Site Code 0.5.3 robot company. Visit our sister sites dmoz.org

39. International: Italiano: Salute: Medicina: Medici E Ricercatori - Open Site temin, howard martin (1); Theiler, Max (0); Theorell, Axel Hugo Theodor (0);Thomas, E. Donnall (0); Tinbergen, Nikolaas (0); Tonegawa, Susumu (0) http://open-site.org/International/Italiano/Salute/Medicina/Medici_e_Ricercatori

Open Site The Open Encyclopedia Project Pagina principale Aggiungi Contenuti Diventa Editore In tutta la Directory Solo in Medicina/Medici_e_Ricercatori Top International Italiano Salute ... Medicina : Medici e Ricercatori Ippocrate Dioscoride Galeno Teofrasto ... Zinkernagel, Rolf Vedi anche: International: Italiano: Societ : Strutture Sociali: Persone: Biografie Questa Categoria ha bisogno di un Editore - Richiedila Open Site Code 0.5.3 robot company. Visit our sister sites dmoz.org mozilla.org chefmoz.org musicmoz.org ... modifica

40. Der Nobelpreis Für Physiologie Oder Medizin: Howard Martin Temin Baltimore und Renato Dulbecco ). howard martin temin *1934, † 1994. PAGERANK SEO. http://www.nobelpreis.org/medizin/temin.htm

vor suchen Home Chemie ... Wirtschaft Howard Martin Temin (USA) "Für ihre Entdeckungen auf dem Gebiet der Wechselwirkungen zwischen Tumorviren und dem genetischen Material der Zelle" ( gemeinsam mit David Baltimore und Renato Dulbecco

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