1. Chemistry 2001 K. Barry Sharpless Autobiography Nobel Lecture Interview Nobel Diploma Prize Award Photo Banquet Speech Other Resources 2000 2002 http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

2. K. Barry Sharpless - Autobiography K. Barry Sharpless Autobiography. From 6th through 12th grades I attended a Quaker school on the Philadelphia city line. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

3. K. Barry Sharpless Winner Of The 2001 Nobel Prize In Chemistry K. Barry Sharpless, the 2001 Nobel Prize Laureate in Chemistry, at the Nobel Prize Internet Archive. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

4. Sharpless Group Useful new reactivity and general methods for selectively controlling chemical reactions. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

5. Sharpless, Former MIT Professor, Wins Nobel In Chemistry - MIT News K. Barry Sharpless, an MIT chemistry professor for 17 years until he joined Scripps Research Institute in 1990, was chosen October 10 to share the http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

6. K. Barry Sharpless - Wikipedia, The Free Encyclopedia K. Barry Sharpless http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

7. K. Barry Sharpless - Wikipedia En Espa Ol K. Barry Sharpless http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

8. Sharpless, K. Barry Sharpless, K. Barry. From 6th through 12th grades I attended a Quaker school on the Philadelphia city line. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

9. Barry Sharpless K. Barry Sharpless (1941 ) Qu mico norte-americano nascido em Philadelphia, Pennsylvania, do Instituto de Pesquisa Scripps, contemplado http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

10. NIGMS News Events NIGMS Grantee K. Barry Sharpless Wins A news release on NIGMS grantee K. Barry Sharpless winning the Nobel Prize in Chemistry for advances in mirrorimage chemistry. http://tmsyn.wc.ask.com/r?t=an&s=hb&uid=24312681243126812&sid=343126

11. The K. Barry Sharpless Lab Useful new reactivity and general methods for selectively controlling chemicalreactions. http://www.scripps.edu/chem/sharpless/

12. K. Barry Sharpless -- Curriculum Vitae K. barry sharpless, Ph.D. Organic/Inorganic Chemist WM Keck Professor of ChemistryThe Scripps Research Institute (TSRI) WM Keck Professor of Chemistry http://www.scripps.edu/chem/sharpless/cv.html

K. Barry Sharpless, Ph.D. Organic/Inorganic Chemist W. M. Keck Professor of Chemistry The Scripps Research Institute (TSRI) W. M. Keck Professor of Chemistry 10550 North Torrey Pines Road La Jolla, California 92037 Tel: 858.784.7505 Fax: 858.784.7562 sharples@scripps.edu Current Research modular click chemistry in situ click assembly in biological hosts transition metal-catalyzed asymmetric processes Biographical born Philadelphia, Pennsylvania, 1941 BA, Dartmouth College (T. A. Spencer), 1963 PhD, Stanford University (E. E. van Tamelen), 1968 postdoctoral, Stanford University (J. P. Collman), 1968 postdoctoral, Harvard University (K. Bloch), 1969 Chemistry Faculties American Assn for the Advancement of Science, 1984 National Academy of Sciences, 1985 Royal Society of Chemistry (Hon.), Great Britain, 1998 Kitasato Institute (Hon.), Japan, 2002 Awarded Fellowships National Science Foundation Doctoral Fellow, 1963 National Institutes of Health Postdoctoral Fellow, 1968

13. K. Barry Sharpless - Autobiography K. barry sharpless From 6th through 12th grades I attended a Quaker school onthe Philadelphia city line. Twice a week the entire school attended Quaker http://nobelprize.org/chemistry/laureates/2001/sharpless-autobio.html

HOME SITE HELP ABOUT SEARCH ... EDUCATIONAL From 6th through 12th grades I attended a Quaker school on the Philadelphia city line. Twice a week the entire school attended Quaker Meeting, silent gatherings except when someone received a personal call to speak. I never got a call, but nonetheless my head was full: I thought about fishing and boats. Or else I thought about when next I could get from Philadelphia to our cottage on the New Jersey Shore in order to go out fishing in a boat. Beneath my picture in one high school yearbook it says, "I'm going to the Shore". While I had an overwhelming passion for fishing, school I merely enjoyed and I never planned to be a scientist. In fact, passion, not planning, is the engine driving all my thought and action. The almost unimaginably good fortune of my youth was that other people made such very, very good plans and choices for me. Generally speaking, colleges have the best undergraduate teaching, and universities, whose labs are filled by graduate and post-graduate students, have the best research. When I arrived at Dartmouth College in 1959, the chemistry department had a graduate program, which meant great teachers who were just as good at research. However, the program was small, and only a master's degree was awarded, so consequently professors were perpetually hungry for more manpower for their labs, more "hands". Undergraduates who performed well in lab courses were actively recruited to do "real" graduate- level research.

14. Chemistry 2001 William S. Knowles, Ryoji Noyori, K. barry sharpless. William S. Knowles,Ryoji Noyori, K. barry sharpless. quarter 1/4 of the prize, quarter 1/4 of the http://nobelprize.org/chemistry/laureates/2001/

HOME SITE HELP ABOUT SEARCH ... EDUCATIONAL The Nobel Prize in Chemistry 2001 "for their work on chirally catalysed hydrogenation reactions" "for his work on chirally catalysed oxidation reactions" William S. Knowles Ryoji Noyori K. Barry Sharpless 1/4 of the prize 1/4 of the prize 1/2 of the prize USA Japan USA St. Louis, MO, USA Nagoya University Nagoya, Japan The Scripps Research Institute La Jolla, CA, USA b. 1917 b. 1938 b. 1941 The Nobel Prize in Chemistry 2001 Press Release Advanced Information Information for the Public ... Other Resources The 2001 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: Nobelprize.org Get to know all 770 Prize Winners! » Games and Simulations » SITE FEEDBACK ... TELL A FRIEND Last modified April 13, 2005

15. K. Barry Sharpless Winner Of The 2001 Nobel Prize In Chemistry K. barry sharpless, the 2001 Nobel Prize Laureate in Chemistry, at the NobelPrize Internet Archive. http://almaz.com/nobel/chemistry/2001c.html

K B ARRY S HARPLESS Nobel Laureate in Chemistry for his work on chirally catalysed oxidation reactions. Background Born: April Place of Birth: Philadelphia, PA, U.S.A. Residence: CA Affiliation: Scripps Research Institute , La Jolla, USA Address: 10550 North Torrey Pines Blvd. La Jolla, CA 92037 Education: Dartmouth College , B. A. 1963 Stanford University , Ph. D. 1968 Book Store Asymmetric Catalysis in Organic Synthesis (The George Fisher Baker Non-Resident Lectureship in Chemistry at Cornell) by Ryoji Noyori (1994) Comprehensive Asymmetric Catalysis (Comprehensive Overviews in Chemistry) by Eric N. Jacobsen (Editor), Andreas Pfaltz (Editor), Hisashi Yamamoto (Editor) (1999) Stereochemistry of Organic Compounds by Ernest L. Eliel, Samuel H. Wilen (Editor), Lewis N. Mander (Editor) (1994) Classics in Total Synthesis : Targets, Strategies, Methods by K. C. Nicolaou, E. J. Sorensen (1995) Asymmetric Synthesis : Chiral Catalysis by James D. Morrison (Editor) (1985) Books about chiral catalysis Featured Internet Links Prize co-recipient: William S. Knowles

16. National Academy Of Sciences - Members sharpless, K. barry The Scripps Research Institute molybdenum, titanium, andosmium, sharpless has discovered new catalytic and stoichiometric http://www4.nationalacademies.org/nas/naspub.nsf/(urllinks)/NAS-58N3YY?opendocum

17. 2000 National Academy Of Sciences Awards sciences and to the benefit of humanity goes to K. barry sharpless, WM KeckProfessor of Chemistry, The Scripps Research Institute, La Jolla, Calif. http://www4.nationalacademies.org/news.nsf/isbn/01122000?OpenDocument

18. K. Barry Sharpless - Wikipedia, The Free Encyclopedia K. barry sharpless sharpless became professor at the Massachusetts Instituteof Technology, Stanford University, and the Scripps Research Institute, http://en.wikipedia.org/wiki/K._Barry_Sharpless

K. Barry Sharpless From Wikipedia, the free encyclopedia. Karl Barry Sharpless (born April 28 ) is a chemist renowned for his work on organometallic chemistry In he won the Nobel Prize in Chemistry for his work on stereoselective oxidation reactions ( Sharpless epoxidation Sharpless bishydroxylation , Sharpless aminohydroxylation). This prize was shared with William S. Knowles and Ryoji Noyori (for their work on stereoselective hydrogenation ). Currently he spends much of his time promoting click chemistry which are selective, exothermic reactions which occur under mild conditions in water; the most successful variant of which is the alkyne azide (3 + 2) cycloaddition to form 1,2,3-triazoles. Sharpless was born in Philadelphia . He began his studies in Dartmouth College and earned his PhD from Stanford University in . He continued post-doctoral work at Stanford University and Harvard University Sharpless became professor at the Massachusetts Institute of Technology Stanford University , and the Scripps Research Institute , where he currently holds the W. M. Keck professorship in chemistry. An interesting personal note, as passed around by graduate students at

19. K. Barry Sharpless: Information From Answers.com K. barry sharpless Karl barry sharpless (born April 28 , 1941 ) is a chemistrenowned for his work on organometallic chemistry. http://www.answers.com/topic/k-barry-sharpless

showHide_TellMeAbout2('false'); Business Entertainment Games Health ... More... On this page: Wikipedia Mentioned In Or search: - The Web - Images - News - Blogs - Shopping K. Barry Sharpless Wikipedia K. Barry Sharpless Karl Barry Sharpless (born April 28 ) is a chemist renowned for his work on organometallic chemistry In he won the Nobel Prize in Chemistry for his work on stereoselective oxidation reactions ( Sharpless epoxidation Sharpless bishydroxylation , Sharpless aminohydroxylation). This prize was shared with William S. Knowles and Ryoji Noyori (for their work on stereoselective hydrogenation ). Currently he spends much of his time promoting click chemistry which are selective, exothermic reactions which occur under mild conditions in water; the most successful variant of which is the alkyne azide [2 + 3] cycloaddition to form 1,2,3-triazoles. Sharpless was born in Philadelphia . He began his studies in Dartmouth College and earned his PhD from Stanford University in . He continued post-doctoral work at Stanford University and Harvard University Sharpless became professor at the Massachusetts Institute of Technology Stanford University , and the Scripps Research Institute , where he currently holds the W. M. Keck professorship in chemistry.

20. Sharpless Bishydroxylation: Information From Answers.com through small amounts of a chiral catalyst is an important concept in organicsynthesis. K. barry sharpless won the 2001 Nobel Prize in Chemistry. http://www.answers.com/topic/sharpless-bishydroxylation

showHide_TellMeAbout2('false'); Business Entertainment Games Health ... More... On this page: Wikipedia Mentioned In Or search: - The Web - Images - News - Blogs - Shopping Sharpless bishydroxylation Wikipedia Sharpless bishydroxylation Sharpless bishydroxylation or asymmetric dihydroxylation (AD) is a chemical reaction of an alkene with osmium tetroxide to form an diol (dialcohol). Chiral products can be formed by adding quinine derivatives. A more efficient way to perform this reaction is reoxidise the osmate, which is formed in the reaction, with potassium ferricyanide . This reduces the amount of the highly toxic and very expensive osmium tetroxide needed by up to 95%. It is possible to buy these mixtures as AD-mix The chiral diols are important for further synthesis. The introduction of chirality (chemistry) into nonchiral reactants through small amounts of a chiral catalyst is an important concept in organic synthesis K. Barry Sharpless won the 2001 Nobel Prize in Chemistry Examples The first step in the synthesis of azasugar is a dihydroxylation reaction of the prochiral diene . Azasugars are pharmacologically relevant. The entire reaction sequence takes place in water as a reaction medium and protective groups were not required. Notice the

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