21. Paul Greengard Lab Laboratory of Molecular and Cellular Neuroscience paul greengard Vincent AstorProfessor. The goal of our laboratory is to understand more fully the http://www.rockefeller.edu/labheads/greengard/greengard-lab.html

Laboratory of Molecular and Cellular Neuroscience Paul Greengard Vincent Astor Professor The goal of our laboratory is to understand more fully the molecular basis of communication between neurons in the mammalian brain. Toward this end, we have developed a general model of signal transduction in the nervous system. The major molecular mechanism underlying signal transduction is protein phosphorylation. Synaptic Vesicle-associated Phosphoproteins. The major synaptic vesicle-associated phosphoproteins that we have identified and characterized are synapsin I, synapsin II, and synaptophysin. As an example of the functioning of this class of phosphoproteins, we have obtained evidence that dephosphorylated synapsin I functions to tether synaptic vesicles in a "reserve" pool. When synapsin I is phosphorylated, this tethering function is abolished, and the synaptic vesicles are then free to enter a "readily releasable" pool of synaptic vesicles. Additionally, we have obtained evidence that the synapsins are involved in the formation of new synapses. Neostriatum-enriched Phosphoproteins.

22. Paul Greengard - Prize Award Photo paul greengard and His Majesty the King. paul greengard receiving his Nobel Prizefrom His Majesty the King. Photo Hans Mehlin, Nobelprize.org http://nobelprize.org/medicine/laureates/2000/greengard-award.html

HOME SITE HELP ABOUT SEARCH ... EDUCATIONAL Paul Greengard receiving his Nobel Prize from His Majesty the King. Photo: Hans Mehlin, Nobelprize.org The Nobel Prize in Physiology or Medicine 2000 Press Release Presentation Speech Educational ... Other Resources The 2000 Prize in: Physics Chemistry Physiology or Medicine Literature ... Economic Sciences Find a Laureate: Nobelprize.org Get to know all 770 Prize Winners! » Games and Simulations » SITE FEEDBACK ... TELL A FRIEND Last modified April 14, 2005

23. Paul Greengard - Autobiography paul greengard – Autobiography. paul greengard. My paternal great, great grandfatheremigrated from Koenigsberg, currently Kalingrad, to St. Louis during http://nobelprize.org/medicine/laureates/2000/greengard-autobio.html

HOME SITE HELP ABOUT SEARCH ... EDUCATIONAL My paternal great, great grandfather emigrated from Koenigsberg, currently Kaliningrad, to St. Louis during the 1850s, a time of large-scale movement of Germans, including German Jews, to the Mid-Western United States. My paternal grandfather moved to Binghamton, New York, where my father was born. My father had success in vaudeville as a singer/dancer/comedian. He eventually became a businessman working first in retail and then in wholesale in the cosmetics field. I attended public schools in Brooklyn and Queens. During World War II, I spent three years in the Navy as an electronics technician. After appropriate training, I was assigned to a team at the Massachusetts Institute of Technology that was involved in developing an early-warning system to intercept Japanese kamikaze planes before they could reach the ships of the U.S. fleet. H. Keffer Hartline , who became Chairman of the Department of Biophysics at Johns Hopkins and who was later to win a Nobel Prize in Physiology or Medicine for his work on vision. I did my first laboratory research under the supervision of Hartline. Shortly after our move to Hopkins

24. National Academy Of Sciences - Members greengard, paul The Rockefeller University. Elected to NAS, 1978. ScientificDiscipline, Cellular and Molecular Neuroscience. Membership Type, Member http://www4.nationalacademies.org/nas/naspub.nsf/(urllinks)/NAS-58N44M?opendocum

25. MSN Encarta - Paul Greengard greengard, paul, born in 1925, American neuroscientist and Nobel laureate whostudied Other Features from Encarta. Search Encarta for greengard, paul http://encarta.msn.com/encyclopedia_681500374/Paul_Greengard.html

MSN Home My MSN Hotmail Shopping ... Sign In Web Search: Encarta Subscriber Sign In Help Home ... Upgrade your Encarta Experience Search Encarta Subscription Article MSN Encarta Premium: Get this article, plus 60,000 other articles, an interactive atlas, dictionaries, thesaurus, articles from 100 leading magazines, homework tools, daily math help and more for $4.95/month or $29.95/year (plus applicable taxes.) Learn more. This article is exclusively available for MSN Encarta Premium Subscribers. Already a subscriber? Sign in above. Greengard, Paul Greengard, Paul , born in 1925, American neuroscientist and Nobel laureate who studied the biochemical steps involved in the way billions of nerve... Related Items Nobel Prize cowinners 2 items Want more Encarta? Become a subscriber today and gain access to: Daily Math Help Literature Guides Researcher Tools Paper-Writing Guides 60,000 + articles Interactive Atlas Magazine Center Find more about Greengard, Paul from Other Features from Encarta Search Encarta for Greengard, Paul © 2005 Microsoft MSN Privacy Legal Advertise Feedback ... Help

26. MSN Encarta - Search Results - Paul Greengard Join Now. Searched Encarta for paul greengard . Articles MSN Encarta Premium.Get more results for paul greengard . 198 results on MSN Encarta http://encarta.msn.com/Paul_Greengard.html

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27. Greengard, Paul greengard, paul (1925). My paternal great, great grandfather emigrated fromKoenigsberg, now Gdansk, to St. Louis during the 1850s, a time of large-scale http://www.cartage.org.lb/en/themes/Biographies/MainBiographies/G/Greengard/Gree

Greengard, Paul My paternal great, great grandfather emigrated from Koenigsberg, now Gdansk, to St. Louis during the 1850s, a time of large-scale movement of Germans, including German Jews, to the Mid-Western United States. My paternal grandfather moved to Binghamton, New York, where my father was born. My father had success in vaudeville as a singer/dancer/comedian. He eventually became a businessman working first in retail and then in wholesale in the cosmetics field. I was born on December 11, 1925 in New York City under tragic circumstances - my mother, née Pearl Meister, died giving birth to me. My father remarried when I was 13 months old. In contrast to my mother, who had been Jewish, my stepmother, who raised me, was Episcopalian. From that time on I was brought up in the Christian tradition, celebrating Easter, Christmas, etc. I was prevented access to my biological mother's family with whom I became familiar only very recently. I have been delighted to learn that many members of that family are highly creative individuals working in various fields of science, government, etc. I attended public schools in Brooklyn and Queens. During World War II, I spent three years in the Navy as an electronics technician. After appropriate training, I was assigned to a team at the Massachusetts Institute of Technology that was involved in developing an early-warning system to intercept Japanese kamikaze planes before they could reach the ships of the U.S. fleet.

28. Paul Greengard Winner Of The 2000 Nobel Prize In Physiology Or Medicine paul greengard, the 2000 Nobel Prize Laureate in Physiology or Medicine, at theNobel Prize Internet Archive. http://almaz.com/nobel/medicine/2000b.html

P AUL G REENGARD 2000 Nobel Laureate in Physiology or Medicine for their discoveries concerning signal transduction in the nervous system Background Born: December 11, 1925 Place of birth: New York, NY, USA Residence: New York Affiliation: Laboratory of Molecular and Cellular Neuroscience, Rockefeller University Address: Laboratory of Molecular and Cellular Neuroscience The Rockefeller University 1230 York Avenue, New York, NY 10021, USA E-mail: greengd@rockvax.rockefeller.edu Book Store Principles of Neural Science, 4th Edition Books on Signal Transduction Books on the nervous system Books on dopamine ... Books by Eric Kandel Featured Internet Links Prize co-recipient: Arvid Carlsson Prize co-recipient: Eric Kandel Paul Greengard Lab at the Rockefeller University Publications ... Curriculum vitae Search WWW Search The Nobel Prize Internet Archive Links added by Nobel Internet Archive visitors Professor Paul Greengard Donates $100,000 for Pearl Meister Distinguished Lecture Paul Greengard - Prize Award Photo (submitted by Daike) Yahoo! Encyclop¨¦die - Paul Greengard

29. Bills And Resolutions greengard, paul. Bills and resolutions. Nobel Prize recognition for physiologyor medicine (see H. Res. 642), H10257 18OC. Remarks in House http://thomas.loc.gov/cgi-bin/query/z?i106:I04618:i106GREEN.html

30. Bills And Resolutions greengard, paul. Bills and resolutions. Nobel Prize recognition for physiologyor medicine (see S. Res. 135), S7805 17JY. Remarks in Senate http://thomas.loc.gov/cgi-bin/query/z?j107:I04875:j107GRAND.html

31. [ISI Highly Cited Researchers Version 1.1] Highly Cited Researcher greengard, paul 1988, Fidia Research FoundationSymposium, to honor paul greengard, Annual Meeting of the Society for http://hcr3.isiknowledge.com/author.cgi?&link1=Browse&link2=Results&id=335

32. [ISI Highly Cited Researchers Version 1.1] Highly Cited Researcher greengard, paul Aitken, A., Bilham, T., Cohen,P., Aswad, D., greengard, P.. A SPECIFIC SUBSTRATE FROM RABBIT CEREBELLUM FOR http://hcr3.isiknowledge.com/formViewCharacteristic.cgi?table=Publication&id=335

33. The Lemelson Center For The Study Of Invention Innovation 19, 10, greengard, paul (Medicine 2000) Transcript, nd. 11, Hewish, Antony (Physics1974) Transcript, 2/8/00. 12, Karle, Jerome (Chemistry 1985) http://invention.smithsonian.org/resources/fa_nobel_index.aspx

Shortcuts for special audiences . . . . Students Teachers Inventors Historians Museum Visitors SEARCH: WM_preloadImages( '../images/interface/side_nav_over-01.gif', '../images/interface/side_nav_over-02.gif', '../images/interface/side_nav_over-03.gif', '../images/interface/side_nav_over-04.gif', '../images/interface/side_nav_over-05.gif', '../images/interface/side_nav_over-06.gif', '../images/interface/side_nav_over-07.gif' ); Did Edison invent anything besides a light bulb? See what other bright ideas he had. Back to "Archives" menu Nobel Voices Video History Project, 3 cubic feet: 16 DB; 4 ShB By Alison L. Oswald, August 2001 Archives Center, National Museum of American History, Smithsonian Institution Table of Contents History Scope and Content Note Provenance Container List History The National Museum of American History, Smithsonian Institution and the Deutsches Museum collaborated in June 2000 to conduct video interviews with thirty-three Nobel Laureates. Interviews were conducted in Lindau, Germany, Washington, D.C., and elsewhere in the United States. The video documentation subsequently formed the core of the Nobel Voices Video History Project and the exhibition Nobel Voices: Celebrating 100 Years of the Nobel Prize . The interviewees were asked about their motivations, visions for the future, and opinions on the nature of creativity and innovation. In the interviews, the laureates speak about their passion for their work, their childhood inspirations, the spirit of discovery, and the personal meaning of the Nobel Prize.

34. Guanosine 3′:5′-Cyclic Monophosphate-Dependent Phosphorylation O John E. Casnellie and paul greengard. 1Department of Pharmacology, Yale UniversitySchool of Medicine, 333 Cedar Street, New Haven, Connecticut 06510 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=388348

35. Phosphorylation Of Membrane Proteins At A Cholinergic Synapse. PubMed; Kebabian, John W.; Petzold, Gary L.; greengard, paul. DopamineSensitiveAdenylate Cyclase in Caudate Nucleus of Rat Brain, and Its Similarity to http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=393239

36. Online NewsHour: A Nobel Winner- October 11, 2000 paul greengard, one of this year’s winners of the Nobel Prize in medicine, paul greengard is a neuroscientist who heads the laboratory of molecular and http://www.pbs.org/newshour/bb/science/july-dec00/nobel-med_10-9.html

A NOBEL WINNER October 11 , 2000 Paul Greengard, one of this year’s winners of the Nobel Prize in medicine, joins Dr. Steve Hyman, director of the National Institute of Mental Health, to talk about his research and winning the Nobel Prize. RAY SUAREZ: The award this year went for discoveries about how messages move around the nervous system and help us understand the functioning of the brain. Three scientists will share the nearly $1 million prize. One of them is with us now. Paul Greengard is a neuroscientist who heads the laboratory of molecular and cellular neuroscience at the Rockefeller University in New York. Also joining us is Dr. Steve Hyman, director of the National Institute of Mental Health. First, Professor Greengard, congratulations. PAUL GREENGARD: Thank you very much. RAY SUAREZ: How did you hear about the award? PAUL GREENGARD: About ten minutes past five this morning, the secretary of the Nobel Committee called to inform me I had been one of the recipients of this year's Nobel Prize in medicine. It was about 20 minutes... apparently in Sweden they announce at 11:30 in the morning, which is 5:30 Eastern Standard time. So they called to let the recipients know in advance of the deluge of telephone calls that come after the announcement of the prize.

37. Online NewsHour: Nobel Prize In Medicine -- October 9, 2000 Ray Suarez talks with paul greengard and Dr. Steve Hyman, Sweden s ArvidCarlsson and Americans paul greengard and Eric Kandel won the 2000 Nobel Prize http://www.pbs.org/newshour/nobel2000/medicine.html

NOBEL PRIZE IN MEDICINE October 9, 2000 Arvid Carlsson , Swedish, 77, University of Gothenburg Paul Greengard , American, 74, Rockefeller University, New York Eric Kandel , Austrian-born American, 70, Columbia University, New York Ray Suarez talks with Paul Greengard and Dr. Steve Hyman, director of the National Institute of Mental Health. Online Special: 2000 Nobel Prizes Oct. 13, 2000: A background report and discussion on peace prize winner Kim Dae Jung Oct. 10, 2000: Nobel Prize winners MacDiarmid and Kroemer talk about their research. An Online Special on the 1999 Nobel Prizes Browse the NewsHour's coverage of Science and Health The Nobel Foundation University of Gothenburg Rockefeller University ... Columbia University Sweden's Arvid Carlsson and Americans Paul Greengard and Eric Kandel won the 2000 Nobel Prize for medicine for their research on how messages are transmitted between brain cells. The Nobel Assembly at Karolinska Institutet said the three had made "pioneering discoveries" in signal transduction between nerve cells in the brain. Their work has helped in understanding how the brain functions and the causes behind neurological and psychiatric diseases.

38. International: Italiano: Salute: Medicina: Medici E Ricercatori: Greengard, Paul Translate this page Italiano Salute Medicina Medici e Ricercatori greengard, paul - Open Site . In tutta la Directory, Solo in Medici_e_Ricercatori/greengard,_paul http://open-site.org/International/Italiano/Salute/Medicina/Medici_e_Ricercatori

Open Site The Open Encyclopedia Project Pagina principale Aggiungi Contenuti Diventa Editore In tutta la Directory Solo in Medici_e_Ricercatori/Greengard,_Paul Top International Italiano Salute ... Medici e Ricercatori : Greengard, Paul Vedi anche: International: Italiano: Societ : Strutture Sociali: Persone: Biografie: Premio Nobel Questa Categoria ha bisogno di un Editore - Richiedila Open Site Code 0.5.3 robot company. Visit our sister sites dmoz.org mozilla.org chefmoz.org musicmoz.org ... modifica

39. Advances In Cyclic Nucleotide And Protein Phosphorylation Research; Author: Gree Author greengard, paul (Et Al) Hardback; Book NonSubscriber ISBN 0881672424This item non-returnable. Order may not be canceled. PRODUCT CODE 0881672424 http://www.opengroup.com/aubooks/088/0881672424.shtml

English Books US/World Maps Sheet Music Musical Supplies ... NEW RELEASES Advances in Cyclic Nucleotide and Protein Phosphorylation Research Author: Greengard, Paul (Et Al) Hardback; Book Non-Subscriber ISBN: 0881672424 This item non-returnable. Order may not be canceled. PRODUCT CODE: 0881672424 USA/Canada: US$ 200.00 Australia/NZ: A$ 127.20 Other Countries: US$ 215.80 convert to your currency Delivery costs included if your total order exceeds US$50. We do not charge your credit card until we ship your order. Government and corporate Purchase Orders accepted without prior account application. PLACE AN ORDER To prepare to buy this item click "add to cart" above. You can change or abandon your shopping cart at any time before checkout. CHECK ORDER STATUS Check on order progress and dispatch. CHANGE OR CANCEL YOUR ORDER Please E-mail us within one hour The NetStoreUSA website is operated by Open Communications, Inc an Arizona corporation, which has successfully served the Internet community since 1994. ®Open Communications is a Registered Trade Mark. This material may be freely distributed ONLY with full reference to Open Communications Inc including fax, phone, e-mail, and world-wide web details.

40. Fisher Center Foundation When paul greengard was a graduate student in the late 1940s, the question ofhow the brain s chemical messengers produce their effect on nerve cells was so http://www.alzinfo.org/fisher/about/bios/greengard/default.aspx

Click the for glossary definitions. Foundation About the Foundation Paul Greengard, Ph.D. Biography Paul Greengard, Ph.D. 2000 Nobel Laureate Director of the Fisher Center for Alzheimer's Research at The Rockefeller University When Paul Greengard was a graduate student in the late 1940s, the question of how the brain's chemical messengers produce their effect on nerve cells was so deeply mysterious and seemed so impossible to answer that most scientists largely avoided asking it. But the young Greengard dared to ask the question, and spent most of the next 50 years unraveling the answers. In the process, he has spawned an entire new branch of neurobiological research, has revolutionized our understanding of the biochemical mechanisms involved in communication between nerve cells and has forged a path to novel treatments for brain disorders such as Alzheimer's disease. Dr. Greengard's pioneering work in delineating how neurons communicate with one another in the brain earned him the 2000 Nobel Prize in Physiology or Medicine. During a half-century of research, he has arguably contributed more than any other single scientist to our understanding of the complex signaling processes that occur within each of the 100 billion or more nerve cells in the human brain. Collectively, these cells orchestrate every aspect of our being - from walking and talking to thinking and feeling emotion to having a unique personality. Understanding these processes enables us to comprehend not only the fundamental nature of brain function, but also what goes wrong in brain diseases such as Alzheimer's and Parkinson's. The ultimate goal, of course, is to develop effective treatments for these devastating disorders.

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