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         Cech Thomas R:     more books (16)
  1. CECH, THOMAS R. (1947- ): An entry from Gale's <i>World of Microbiology and Immunology</i>
  2. Molecular Biology of RNA: Proceedings of a Director's Sponsors-UCLA Symposium, Held at Keystone, Colorado, April 4-10, 1988 (UCLA Symposia on Molecular and Cellular Biology)
  3. Genes We Share With Yeast, Flies, Worms and Mice: New Clues to Human Health and Disease
  4. Science at liberal arts colleges: a better education?(Distinctively American: The Residential Liberal Arts Colleges): An article from: Daedalus by Thomas R. Cech, 1999-01-01
  5. The Double Life of RNA (Howard Hughes Medical Institute Holiday Lectures on Science) by Thomas R. Cech, 2006
  6. Daedalus - Journal of the American Academy of Arts and Sciences (Distrinctively American - The Residential Liberal Arts Colleges, Winter 1999) by Alexander W. Astin, Susan C. Bourque, et all 1999
  7. The Harvey Lectures: Delivered Under the Auspices of The Harvey Society of New York 1986-1987 by Steven; Thomas R Cech et al Borstein, 1988
  8. The Harvey Lectures by Steven; Thomas R. Cech et al Borstein, 1988-05
  9. The Double Life of RNA; VHS Format by Thomas R. Cech, 1995
  10. The RNA World, 2nd edition (Monograph 37) (Cold Spring Harbor Monograph) by Raymond F. Gesteland, Thomas R. Cech, et all 2000-06-01
  11. RNA Worlds: From Life's Origins to Diversity in Gene Regulation
  12. (WCS)Principles of Water Resources w/ Study Tips SET by Thomas R. Cech, 2004-11-17
  13. Molecular Biology Of RNA Proceedings of a Director's Sponsors-Ucla Symposium, He by Thomas R. (editor) Cech, 1989-01-01
  14. The Rna World (Cold Spring Harbor Monograph Series) (Cold Spring Harbor Monograph Series) by Thomas R. Cech, 1980

61. ChIN S Summary Page Thomas R. Cech, University Of Colorado, USA
This is the summary page for thomas R. cech, University of Colorado, USA on CSDLChIN.
http://chemport.ipe.ac.cn/cgi-bin/chemport/getfiler.cgi?ID=XTlT8Feft9QifSec9BzaB

62. ChIN?Thomas R. Cech(1989?

http://chemport.ipe.ac.cn/cgi-bin/chemport/getfiler.cgi?ID=XTlT8Feft9QifSec9BzaB

63. Edward Tufte: New ET Writings, Artworks & News
astronomer Jocelyn Bell Burnell,; biochemist thomas R. cech, Dr. thomas R.cech, who became president of the Howard Hughes Medical Institute in 2000,
http://www.edwardtufte.com/tufte/williams
WILLIAMS COLLEGE Office of Public Affairs
P.O. Box 676, Williamstown, MA 01267, USA
tel: 413-597-4277; fax: 413-597-4158
e-mail: news@williams.edu Williams College to Honor Eight Renowned Scientists
and Dedicate New Science Center, Sept. 23 WILLIAMSTOWN, Mass., August 2, 2000 Williams College will honor eight distinguished scientists at its Fall Convocation. President of the College Morton Owen Schapiro will confer the honorary degrees on Saturday, Sept. 23, at 10 a.m. in Chapin Hall. Dr. Rita R. Colwell, director of the National Science Foundation, will give the principal address. Receiving honorary degrees will be
  • astronomer Jocelyn Bell Burnell, biochemist Thomas R. Cech, microbiologist Rita R. Colwell, physicist Daniel Kleppner, computer scientist Donald E. Knuth, psychologist George A. Miller, geologist William B. F. Ryan, professor of political science, statistics, and computer science, Edward R. Tufte.
The college's $47 million science center, including the new Morley Science Laboratories and Schow Science Library, will be dedicated in the afternoon. The new facilities uniquely integrate science activities across all disciplines. Honorary Degree Recipients Convocation speaker Dr. Rita Colwell is director of the National Science Foundation. Former president of the University of Maryland Biotechnology Institute and professor of microbiology at the University of Maryland, Dr. Colwell was a member of the National Science Board from 1984 to 1990 and has held numerous other advisory positions in the U.S. Government, private foundations, as well as in the international community. She is the author or co-author of 16 books and more than 500 scientific publications. She produced the award-winning film, "Invisible Seas."

64. Nat' Academies Press, Sharing Publication-Related Data And Materials: Responsibi
thomas R.cech, Chair. Dr. cech is President of the Howard Hughes Medical Institute.He is also a Distinguished Professor at the University of Colorado,
http://www.nap.edu/books/0309088593/html/81.html
Read more than 3,000 books online FREE! More than 900 PDFs now available for sale HOME ABOUT NAP CONTACT NAP HELP ... ORDERING INFO Items in cart [0] TRY OUR SPECIAL DISCOVERY ENGINE Questions? Call 888-624-8373 Sharing Publication-Related Data and Materials: Responsibilities of Authorship in the Life Sciences (2003)
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Openbook Linked Table of Contents Front Matter, pp. i-xvi Executive Summary, pp. 1-16 1. Study Overview and Background, pp. 17-26 2. The Purpose of Publication and Responsibilities for Shari..., pp. 27-34 3. Sharing Data and Software, pp. 35-50 4. Sharing Materials Integral to Published Findings, pp. 51-60 5. Different Interpretations of Existing Standards, pp. 61-68 6. Encouraging Compliance with and Continuing the Developmen..., pp. 69-78 References, pp. 79-80 Appendix A: Committee Biographies, pp. 81-87 Appendix B: Workshop Agenda and Situations, pp. 89-104 GO TO PAGE:
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65. Nat' Academies Press, Making The Nation Safer: The Role Of Science And Technolog
thomas R. cech, Howard Hughes Medical Institute. David Franz, Southern ResearchInstitute. Claire Fraser, Institute for Genomic Research
http://www.nap.edu/books/0309084814/html/389.html
Read more than 3,000 books online FREE! More than 900 PDFs now available for sale HOME ABOUT NAP CONTACT NAP HELP ... ORDERING INFO Items in cart [0] TRY OUR SPECIAL DISCOVERY ENGINE Questions? Call 888-624-8373 Making the Nation Safer: The Role of Science and Technology in Countering Terrorism (2002)
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Openbook Linked Table of Contents Front Matter, pp. i-xxiv Executive Summary, pp. 1-24 1. Introduction, pp. 25-38 2. Nuclear and Radiological Threats, pp. 39-64 3. Human and Agricultural Health Systems, pp. 65-106 4. Toxic Chemicals and Explosive Materials, pp. 107-134 5. Information Technology, pp. 135-176 6. Energy Systems, pp. 177-209 7. Transportation Systems, pp. 210-237 8. Cities and Fixed Infrastructure, pp. 238-266 9. The Response of People to Terrorism, pp. 267-286 10. Complex and Interdependent Systems, pp. 287-312 11. The Significance of Crosscutting Challenges and Technolo..., pp. 313-334 12. Equipping the Federal Government to Counter Terrorism, pp. 335-356 13. Essential Partners in a National Strategy: States and Ci..., pp. 357-371

66. The Lasker Foundation | Former Award Winners, Basic Medical Research 1988
thomas R. cech, Ph.D. For his revolutionary research revealing the enzymatic roleof RNA, opening a new universe in molecular biology.
http://www.laskerfoundation.org/awards/library/1988basic.shtml
Lasker Awards Jury Members This Year's Winners Former Winners Library of Laureates
Browse the Library for former winners of the Albert Lasker Basic Medical Research Award select Clinical Research Award select Public Service Award select Special Achievement Award select Nominations
Open call to...
Nominate a Scientist

Former Winners, 1988
Albert Lasker Award for Basic Medical Research
Thomas R. Cech, Ph.D.
For his revolutionary research revealing the enzymatic role of RNA, opening a new universe in molecular biology. Phillip A. Sharp, Ph.D.
For his series of revelations regarding the ability of RNA processing to convert DNA's massive store of genetic data to biological use.

67. Science Timeline
cech, thomas R., 1981. Celsius, Anders, 1727, 1742. Cerf, Vinton, 1973. CERN,1990, 1992, 1998. Cesalpino, Andrea, 1250, 1583. Cezanne, Paul, 1872
http://www.sciencetimeline.net/siteindex_c.htm
use checkboxes to select items you wish to download
Select Index Letter:
a
b c d ... w-x-y-z
Cacciatore, Niccola, 1835 Calcidius, middle third century calendar stones, 4800 bce Calvin, Melvin, 1957, 1969 Cambridge Instruments, 1965 Camerarius, Rudolph Jakob, 1694 Cameron, Alastair G. W., 1957 Campbell, Douglas E., 1991 Canano, Giambattista, 1541 Cann, Rebecca, 1987 Cannizzaro, Stanislao, 1855 Cannon, Walter, 1932 Cantor, Georg, 1869 Cao, Tian Yu, 1997 Cardano, Girolamo, 1545, 1554, 1562 Carlisle, Anthony, 1800 Carnot, Lazare Nicolas Marguerite, 1783, 1803 Carothers, Wallace Hume, 1937 Carrier, Willis H., 1901 Carruthers, Marvin, early 1980s Carson, Rachel Louise, 1962 Carter, Brandon, 1970 Carus, Carl Gustav, 1846 Casaubon, Isaac, 1614

68. CALENDAR Master Page
thomas R. cech on RNA Catalysis Discovery, Origins of Life and Medical thomas R. cech on How to Accelerate a Reaction 100000000000fold Using Only
http://www.psu.edu/ur/archives/intercom_1996/April4/cal.html

69. College Of Chemistry Facts And Figures
1987thomas R. cech 1988-Michael G. Rossman 1989-Lubert Stryer 1990-Joanne Stubbe 1990 thomas R. cech 1991 Kurt Wuthrich 1992 Daniel E. Koshland, Jr.
http://chemistry.berkeley.edu/editor/COC_facts/coc_prizes.html

Welcome from the Dean
College Facts Faculty Awards History ... Online Tours College of Chemistry Prizes and Lectureships
Explore the College
College Facts Faculty Honors and Awards : College Prizes and Lectureships
Bayer Lecturers
1996 Gregory Stephanopoulos
1997 E. Terry Papoutsakis
1998 Douglas A. Lauffenburger
1999 George Georgiou
2000 Frances Arnold
2001 Bernhard Palsson
2002 Linda G. Griffith 2005 Michael Betenbaugh (back to the top) Berkeley Lecturers in Chemical Engineering 1994-Sheldon K. Friedlander 2003- Pablo G. DeBenedetti

70. The RNA World. By Brig Klyce
thomas R. cech, A model for the RNAcatalyzed replication of RNA p 4360-4363 v 83 Zaug, Arthur J. and thomas R. cech. The Intervening Sequence RNA of
http://www.panspermia.org/rnaworld.htm
COSMIC ANCESTRY Quick Guide Next The undreamt-of breakthrough of molecular biology has made the problem of the origin of life a greater riddle than it was before: we have acquired new and deeper problems. Nobody understands the origin of life. If they say they do, they are probably trying to fool you. We emerge inevitably or by luck from the chipping of DNA by cosmic rays, chemical currents in space, the bubbling of volcanic mud.
The RNA World What'sNEW
Virtually all biologists now agree that bacterial cells cannot form from nonliving chemicals in one step. If life arises from nonliving chemicals, there must be intermediate forms, "precellular life." Of the various theories of precellular life, the most popular contender today is "the RNA world." RNA has the ability to act as both genes and enzymes. This property could offer a way around the "chicken-and-egg" problem. (Genes require enzymes; enzymes require genes.) Furthermore, RNA can be transcribed into DNA, in reverse of the normal process of transcription. These facts are reasons to consider that the RNA world could be the original pathway to cells. James Watson enthusiastically praises Sir Francis Crick for having suggested this possibility It was prescient of Crick to guess that RNA could act as an enzyme, because that was not known for sure until it was proven in the 1980s by Nobel Prize-winning researcher Thomas R. Cech

71. 59 MIT-related Nobel Prize Winners Include Faculty, Researchers, Alumni And Staf
MIT Radiation Laboratory 194042. Sidney Altman, Chemistry, MIT SB 1960, sharedwith. thomas R. cech, MIT postdoctoral researcher 1975-76
http://web.mit.edu/newsoffice/special/nobels.html
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59 MIT-related Nobel Prize winners include faculty, researchers, alumni and staff
May 9, 2004; updated October 5, 2004 Fifty-nine current or former members of the MIT community have won the Nobel Prize. They include 24 professors, 23 alumni (including three of the professors), 14 researchers and one staff physician. Twenty-six of the Nobel Prizes are in physics, eleven in chemistry, twelve in economics, eight in medicine/physiology, and two in peace. Eight Nobel prizes were won by researchers who helped develop radar at the MIT Radiation Laboratory. Nobelists who are current members of the MIT community are Drs. Wilczek (2004), Horvitz (2002), Ketterle (2001), Molina (1995), Sharp (1993), Friedman (1990), Tonegawa (1987), Solow (1987), Ting (1976) Samuelson (1970), and Khorana (1968). Frank Wilczek,

72. Awards And Honors: Nobel Prize
cech, thomas R. shared Chemistry, 1989; Ciechanover, Aaron - shared Chemistry2004; thomas, E. Donnall - shared Medicine/Physiology, 1990; Wilkinson,
http://web.mit.edu/ir/pop/awards/nobel.shtml
P OPULATION A WARDS AND ... ONORS O FFICE OF THE P ROVOST
Provost Home

Institutional Research
Awards and Honors American Academy of Arts and Sciences American Association for the Advancement of Science CAREER Award John Bates Clark Medal Crafoord Prize Dirac Medal Franklin Institute Awards Fulbright Scholars Program Gairdner Award Gregori Aminoff Prize Guggenheim Fellows HHMI Investigators Institute of Medicine Japan Prize Kyoto Prize Lemelson-MIT Awards MacArthur Fellows NAE NAS National Book Award National Medal of Science National Medal of Technology
Nobel Prize Pulitzer Prize Alan T. Waterman Award -Student Honors- Fulbright Fellows Marshall Scholars Rhodes Scholars -MIT Only- Levitan Prize Nobel Prize Nobel Foundation Royal Swedish Academy of Sciences Current faculty: 8

73. INDUSTRYWEEK: LEADERSHIP IN MANUFACTURING --
cech, thomas R., University of Colorado, 1999 Cerf, Vinton G., MCI CommunicationsCorp., 1994 Chambon, Pierre, Institute of Genetics Molecular Cellular
http://www.industryweek.com/research/techandinn/articles.asp?ArticleID=376

74. RNA WORLD
cech, thomas R., RNA AS AN ENZYME, Scientific American, 255, 5, Nov 1986, 6475.Darnell, James E. Jr., RNA, Scientific American, 253, 4, Oct 1985, 68-78.
http://www.lawrenceroberge.com/RNAWORLD.htm
THE RNA WORLD PAGE
Based on The New York Times article: Inside The Cell, Experts See Life's Origin , Wade, N., April 4, 1999, pgs. 1,4.
ALSO: see Gesteland, R.F., Cech, T.R., Atkins, J.F., eds., 1999. THE RNA WORLD , 2nd. Edition, Monograph 37, Cold Spring Harbor, Cold Spring Harbor Press. DNA/RNA/PROTEIN RNA WORLD ALTERNATIVE THEORIES SUGGESTED READINGS ... GLOSSARY
WHAT IS THE RNA WORLD THEORY?
THE RNA WORLD THEORY states that during the evolution of life on Earth, RNA was the precursor molecule (i.e. came before DNA/RNA/PROTEIN) of basic biochemical functions for early life forms. If you are comfortable with the basics, click to the site listed RNA WORLD for further details about the RNA World Theory.
REVIEW: COMPARE WITH CENTRAL DOGMA OF MOLECULAR BIOLOGY:
TRANSCRIPTION TRANSLATION
DNA
RNA ... PROTEINS LINKS FOR REVIEWING CENTRAL DOGMA CONCEPTS: ACCESS EXCELLENCE: GREAT REVIEW OF THE CENTRAL DOGMA BIOLOGY LEARNING CENTER: SIMPLE REVIEW OF THE CENTRAL DOGMA BIOLOGY LEARNING CENTER: GREAT REVIEW OF DNA REPLICATION FOR LINKS TO FURTHER REVIEWS: TRANSCRIPTION: FROM DNA TO RNA: FROM THE MOLECULAR BIOLOGY NOTEBOOK ACCESS EXCELLENCE PAGE: RNA SYNTHESIS AND PROCESSING BIOLOGY LEARNING CENTER: TRANSCRIPTION-MORE IN DEPTH APPROACH TRANSLATION: ACCESS EXCELLENCE: TRANSLATION (PROTEIN SYNTHESIS) BIOLOGY LEARNING CENTER: TRANSLATION-MORE IN DEPTH APPROACH BIOLOGY LEARNING CENTER: PRIMER ON THE GENETIC CODE: NUCLEIC ACID TO AMINO ACIDS FROM RNA TO PROTEINS: FROM THE MOLECULAR BIOLOGY NOTEBOOK ... QUICK TIME ANIMATION (REQUIRES QUICK TIME PLUG-IN): Developed by Dr. Lorraine Heidecker, this excellent animation describes the translation process: just click on the term RNA ANIMATION.

75. HHMI News: Wanted: More $1 Million Professors
thomas R. cech. The HHMI professors are part of the Institute s longterm planfor improving science education at all levels, to help generate the next
http://www.practicingsafescience.org/news/021505.html

Graduate Program and Group Leader Recruiting Move Forward at Janelia
42 Biomedical Scientists Worldwide Named HHMI International Research Scholars Medical Students Win HHMI Research Awards More
FOR FURTHER
INFORMATION:
Jennifer Donovan
donovanj@hhmi.org

Cindy Fox Aisen
aisenc@hhmi.org

Howard Hughes
Medical Institute
February 15, 2005 Wanted: More $1 Million Professors One hundred research universities are being invited to nominate one or two of their best scientist-educators. In 2006, up to 20 will be named HHMI professors and receive four-year awards of $1 million each. Thomas R. Cech The HHMI professors are part of the Institute's long-term plan for improving science education at all levels, to help generate the next generation of research scientists, as well as a more science-literate public. To date, HHMI has awarded more than $600 million to public and private colleges and universities, as well as $20 million to HHMI professors. The new HHMI professors will have big shoes to fill. The first professors, chosen in 2002, have shared the excitement of scientific research and discovery with undergraduates and others in a wide variety of ways. For example:
  • Northwestern University's Hilary Godwin used to worry over the fact that so few minorities take freshman chemistry. She is changing that with a course based on her own research into the molecular mechanism of lead poisoning, engaging incoming freshmen by sending them into Chicago's community gardens to analyze soil samples for lead.

76. HHMI News: Visualización Del Extremo Del Genoma Humano
Translate this page thomas R. cech. Pero las células también poseen una enzima única conocida comotelomerasa que puede alargar a los telómeros al agregar ADN a los extremos
http://www.practicingsafescience.org/news/cech2-esp.html

El cerebro sigue evolucionando
Un disparo: Investigadores toman fotos de los eventos de fusión que le permiten al espermatozoide penetrar la cubierta del óvulo El cromosoma Y humano se conserva mejor que el Y de chimpancé
noviembre 21, 2004
Visualización del extremo del genoma humano La proteína POT1 se une al extremo de un cromosoma humano por medio de dos pliegues de unión de oligonucleótido/oligosacárido, que se muestran aquí en verde y azul. El ADN telomérico de una sola cadena está representado en rojo. Nature Structural and Molecular Biology
Imagen: Thomas R. ech
Thomas R. Cech Image: Thomas R. Cech El cerebro sigue evolucionando Un disparo: Investigadores toman fotos de los eventos de fusión que le permiten al espermatozoide penetrar la cubierta del óvulo El cromosoma Y humano se conserva mejor que el Y de chimpancé NOTICIAS DEL INSTITUTO Becarios de Investigación Internacionales de Enfermedades Infecciosas y Parasitología del HHMI de 2005 42 científicos biomédicos de todo el mundo han sido nombrados becarios de investigación internacionales del HHMI El HHMI busca investigadores latinoamericanos y canadienses excepcionales
English Version

Investigador del HHMI
Thomas R. Cech

77. The Chronicle Of Higher Education: Complete Contents
universities would benefit by teaming up and integrating their resources,writes thomas R. cech, president of the Howard Hughes Medical Institute.
http://chronicle.com/chronicle/v47/4723guide.htm
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CRITICAL MASS

The University of Maryland at College Park has had unusual success in graduating black students from a Ph.D. program in mathematics.
THE OFFICIAL SECRETS ACT

When a scholar signed a publisher's confidentiality agreement, little did he know how the document would govern his life. Dennis Baron, a professor of English and linguistics at the University of Illinois at Urbana-Champaign, describes what happened.
PROFESSORS AS PROTAGONISTS

Three new novels by academics skewer college life with pinpoint precision, writes Elaine Showalter, a professor of English at Princeton University.
A CHANGE OF FAITH: Duquesne University, a Roman Catholic institution, barred a professor who became an Episcopal priest from teaching theology.
STAYING AWAY: Some scholars will skip the annual meeting of the National Women's Studies Association, citing inadequate child care.
GENDER EQUITY: A new report says that the Massachusetts Institute of Technology was too quick to say that female scientists experienced bias.

78. Scientific American Annual Index 1986
RNA AS AN ENZYME, by thomas R. cech; November, page 76. ROMAN APARTMENT COMPLEX,A, by Donald J. Watts and Carol Martin Watts; December, page 116.
http://www.th.physik.uni-frankfurt.de/~jr/toc/scam86.html
Scientific American Annual Index 1986
AUTHORS
  • Abbott, Allan V., Alec N. Brooks and David Gordon Wilson. HUMAN-POWERED WATERCRAFT; December, page 108.
  • Ahlquist, Jon E., and Charles G. Sibley. RECONSTRUCTING BIRD PHYLOGENY BY COMPARING DNA'S; February, page 68.
  • Anderson, Dana Z. OPTICAL GYROSCOPES; April, page 86.
  • Anstis, Stuart M., and Vilayanur S. RamaChandran. THE PERCEPTION OF APPARENT MOTION; June, page 80.
  • Aubert, James H., Andrew M. Kraynik and Peter B. Rand. AQUEOUS FOAMS; May, page 58.
  • Baer, Eric, ADVANCED POLYMERS; October, page 156.
  • Baer, William C. THE SHADOW MARKET IN HOUSING; November, page 27.
  • Bergner, Lawrence, Mickey S. Eisenberg, Alfred P. Hallstrom and Richard O. Cummins. SUDDEN CARDIAC DEATH; May, page 25.
  • Betz, A. Lorris, and Gary W. Goldstein. THE BLOOD-BRAIN BARRIER; September, page 70.
  • Blaustein, Andrew R., and Richard K. O'Hara. KIN RECOGNITION IN TADPOLES; January, page 90.
  • Borgia, Gerald. SEXUAL SELECTION IN BOWERBIRDS; June, page 70.
  • Bowen, Kent H. ADVANCED CERAMICS; October, page 146.
  • Bowsher, John, Don Smithers and Klaus Wogram. PLAYING THE BAROQUE TRUMPET; April, page 104.

79. Cech, Thomas R. /1947 /WWW.MLP.CZ
Mestská knihovna v Prazeoficiální internetové strány.
http://www.mlp.cz/cz/offline/perlie/C/2043196.htm
Mìstská knihovna v Praze / Municipal library of Prague Seznam autorit / A list of personages
Cech, Thomas R. /1947
(amer. biochemik èes.pùv.; Nobelova cena za chemii 1989)
Záhlaví: Název OCH Rok Signatura Druh dokumentu Svazky BROŽ, Ivan: 20. století jaké bylo D+ D 13051 kniha svazky RECHCÍGL, Miloslav: Postavy naší Ameriky D+ D 13312 kniha svazky Poslední aktualizace: 12.8.2005; Generováno systémem Perlie 1.2

80. Genome Biology | Abstract | Global Expression Changes Resulting From Loss Of Tel
Correspondence thomas R cech. Email thomas.cech@Colorado.edu Genome Biology2004, 6R1 doi10.1186/gb-2004-6-1-r1
http://genomebiology.com/2004/6/1/r1/abstract
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Key E-mail Corresponding author Research Global expression changes resulting from loss of telomeric DNA in fission yeast Jeffrey G Mandell Thomas A Volpe Robert A Martienssen and Thomas R Cech Department of Chemistry and Biochemistry and Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309-0215, USA The Wellcome Trust Sanger Institute, Cambridge, CB10 1SA, UK Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA Genome Biology Published Subject areas: Molecular biology, Cell biology, Genetics, Genome studies, Model organisms Abstract Background Schizosaccharomyces pombe cells lacking the catalytic subunit of telomerase (encoded by ) lose telomeric DNA and enter crisis, but rare survivors arise with either circular or linear chromosomes. Survivors with linear chromosomes have normal growth rates and morphology, but those with circular chromosomes have growth defects and are enlarged. We report the global gene-expression response of

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