121. Scientists Congratulated On Human Genome Project The six countries that worked together on mapping the entire human genome have welcomed the completion of the project. They call for the new information to http://www.number-10.gov.uk/output/Page3487.asp

Skip to: Content Directgov Gov news Main menu prime minister contact biography speeches ... newsroom latest news news by subject media centre email updates downing street ... Help Search You are here: home newsroom latest news > Scientists congratulated on human genome project Scientists congratulated on human genome project 14 April 2003 The six countries that worked together on mapping the entire human genome have welcomed the completion of the project. The information that the Human Genome Project has produced about our DNA will enable scientists to identify why changes in the usual code can lead to diseases developing. When the project began in 1990 it was expected to take 15 years, but advances in technology have allowed the work to finish ahead of schedule and under budget. Hundreds of scientists in the UK, China, France, Germany, Japan and the US were involved. The UK was the largest contributor to the project. One third of the human genome was sequenced at the Wellcome Trust's Sanger Institute and it was the first to publish the complete sequence of an entire chromosome. The Heads of Government of the six countries released the following statement: We, the Heads of Government of the United States of America, the United Kingdom, Japan, France, Germany and China, are proud to announce that scientists from our six countries have completed the essential sequence of three billion base pairs of DNA of the Human Genome, the molecular instruction book of human life.

122. Online NewsHour: A Discussion With Matt Ridley, Author Of 'Genome' -- February 2 The Human Genome Project American Society of Gene Therapy Are we at risk of turning all the kinds of variations of human randomness, our wonderful http://www.pbs.org/newshour/bb/science/jan-june00/genome_2-29.html

GENOME: AN AUTOBIOGRAPHY February 29, 2000 Senior Correspondent Ray Suarez talks with author Matt Ridley about his new book Genome: The Autobiography of a Species in 23 Chapters , about the opportunites and moral challenges the Human Genome Initiative presents to society. Mr. Ridley will also answer your questions in an online forum Online Health Special: Gene Therapy Participate in an online forum with Matt Ridley Feb. 2, 2000: A Univ. of Pennslyvania gene therapy program comes under fire. Dec. 8, 1999: A look at the safety of gene therapy Dec. 2, 1999: Scientists announced the completion of a major step in breaking the human genetic code June 16, 1999: A conversation with Free Dyson author of The Sun, the Genome, and the Internet: Tools of Scientific Revolution. Browse the NewsHour's health coverage. The Human Genome Project American Society of Gene Therapy Human Gene Therapy RAY SUAREZ: We're unraveling one of the biggest scientific discoveries concerning one of the smallest bits of information, the human genetic code. A new book, Genome: The Autobiography of a Species in 23 Chapters , explains how mapping out our human DNA could change everything from medicine and politics to what it means to be human. The author of the book, Matt Ridley, is a former editor of the

123. NOVA Online | Cracking The Code Of Life From Pythagoras to the Human Genome Project and beyond, find out in this timeline how our understanding of heredity has changed throughout history. http://www.pbs.org/wgbh/nova/genome/

Welcome to the companion Web site to "Cracking the Code of Life," originally broadcast on April 17, 2001. This two-hour special, hosted by ABC "Nightline" correspondent Robert Krulwich, chronicles the race to capture one of the biggest prizes in scientific history: the complete letter-by-letter sequence of genetic information that defines human life the human genome. Here's what you'll find online: Watch the Program Here Beginning April 18, watch the entire two-hour NOVA program "Cracking the Code of Life" online, available in both QuickTime and RealVideo, and closed captioned for deaf and hard-of-hearing viewers. Our Genetic Future (A Survey) Would you want to know if you had a genetic predisposition to a terminal disease, even if that disease was incurable? Should genes be patentable? Who, if anyone, should have access to your genomic information? We'd like to hear your thoughts on these and other questions. Manipulating Genes: How Much is Too Much? Few have given more thought to the moral and ethical implications of molecular medicine than Dr. Philip Kitcher, a philosopher at Columbia University and author of The Lives to Come: The Genetic Revolution and Human Possibilities.

124. BioethicsWeb - The Gateway For Internet Resources In Biomedical Ethics, Provided It provides access to information about the Human Genome Project, the Genomes to Life Of particular interest is a history of the Human Genome Project. http://bioethicsweb.ac.uk/browse/mesh/D016045.html

low graphics Top Biomedicine Genomics ... Human Genome Project Human Genome Project Bioethics The Bioethics section of the Woodrow Wilson Leadership Program in Biology which is part of the Woodrow Wilson National Fellowship Foundation, an 'independent, nonprofit organization dedicated to the encouragement of excellence in education through the identification of critical needs and the development of effective national programs to address them'. The page is split into topics (Introduction, Ethical Systems, Process, Case Studies, Biotechnology, New Reproductive Techniques (NRT) and Environmental) containing links to detailed lesson plans (Objectives, Materials, Tasks sheets and References). Other links include the Biology Institute participants and staff, The National Science Foundation, Access Excellence and the Woodrow Wilson National Fellowship Foundation. A search facility is available. United States Transplantation Scientific Misconduct Plants, Genetically Modified ... Bioethics Website.ca The Bioethics Website.ca is hosted by The Bioethics Initiative of SouthWestern Ontario, a 'collaborative venture of the region's health care, research, and academic communities' whose mission is 'leading the search for ethically sound options.' The home page contains a bulletin board with links to announcements and events (past and present). Other sections of the site include What is Bioethics; Headlines (links to newspaper and journal articles); Thinking in Bioethics (case studies, discussion guides); Education; People in Bioethics; Resources in Bioethics (links to other projects); Bioethics Initiative (detailed information about the organization and Advisory Group reports downloadable in Adobe Acrobat pdf); and Site Map (site navigation).

125. Human Genome Project Human Genome Project. Question I was watching a documentary on DNA for my science Thank you, Karla Schroeder Answer The Human Genome Project is the http://www.newton.dep.anl.gov/askasci/bio99/bio99174.htm

Ask A Scientist Biology Archive Human Genome Project Back to Biology Ask A Scientist Index NEWTON Homepage Ask A Question ... NEWTON is an electronic community for Science, Math, and Computer Science K-12 Educators. Argonne National Laboratory, Division of Educational Programs, Harold Myron, Ph.D., Division Director.

126. The WWW VL Public Health: Selected Topics - Human Genome Project Links to resources on Human Genome Project. VL.GIF, WWW VL Public Health Selected Topics, Human Genome Project http://www.ldb.org/vl/top/top-hgp.htm

This site is being preserved as it was on 17 September 2001 as a memorial to the life and work of Eberhard Wenzel. The public health virtual library is now updated and hosted by the UNSW School of Public Health. WWW VL Public Health : Selected Topics HUMAN GENOME PROJECT Topic's Information Site Compass Reference Note Topic's Information Screw us once, shame on you. Screw us twice, shame on us! Jessica Zafra, 1995 (journalist from the Philippines) Australian GeneEthics Network a network of people and organizations being critical with what the Human Genome Project is all about a forum to discuss social and ethical implications of the Human Genome Project, based at the University of Pennsylvania (USA) Council for Responsible Genetics a non-profit organization based in the USA Eubios Ethics Institute a nonprofit group that aims to stimulate the international discussion of ethical issues, and how we may use technology in ways consistent with "good life"; (eu-bios). It aims at an integrated and cross-cultural approach to bioethics, and at building up an international network Eugenics Archive "invite you to experience the unfiltered story of American eugenics primarily through materials from the Eugenics Record Office at Cold Spring Harbor, which was the center of American eugenics research from 1910-1940. In the Archive you will see numerous reports, articles, charts, and pedigrees that were considered scientific "facts" in their day. It is important to remind yourself that the vast majority of eugenics work has been completely discredited. In the final analysis, the eugenic description of human life reflected political and social prejudices, rather than scientific facts"

127. Learning About The Human Genome. Part 1: Challenge To Science Educators. ERIC Di On October 1, 1990, a projectthe Human Genome Project (HGP)-aimed at mapping and Bioethical dilemmas Decision-making and the Human Genome Project. http://www.ericdigests.org/2003-2/genome.html

Site Links Home Search for ERIC Digests Privacy Policy Resources for Library Instruction ... Information Literacy Blog Learning about the Human Genome. Part 1: Challenge to Science Educators. ERIC Digest. by Haury, David L. We have reached a new milestone in our quest to understand ourselves. On February 15, 2001, the International Human Genome Sequencing Consortium published a landmark report: "Initial sequencing and analysis of the human genome" ("Nature," Vol. 409). As I thumb through the maps of human chromosomes presented in the report, I am both amazed and humbled by the accomplishment. The international collaboration of specialists in computing, mathematics, molecular genetics, technology, and other sciences to accomplish this task and usher us into the modern era of biotechnology has been extraordinary. At the same time, the potential consequences of using the resulting information and skills are humbling. "We've now got to the point in human history where for the first time we are going to hold in our hands the set of instructions to make a human being." John Sulston, UK Sanger Centre (For more reactions, see: http://news.bbc.co.uk/hi/english/sci/tech/newsid_807000/807126.stm). Decoding the human genome brings new meaning to "the information age." In a few short years we have progressed beyond creating digital books and encircling the globe with the World Wide Web to documenting the full text of the genetic code that describes how to assemble and operate a human being. We may not yet know how to interpret all the text, let alone follow the recipe, but it is being recorded in full detail on the Web for anyone in the world to see. From the perspective of digital information, this is the book of human life, and decoding it is a phenomenal accomplishment of scientific thinking and our creative use of technology. The only thing more astounding is that this genetic recipe has been stored, read, and translated by every nucleated cell in every human that has ever lived.

128. C&EN: TODAY'S HEADLINES - HUMAN GENOME PROJECT FINISHED Unlike the plans for the Human Genome Project, the plan for the future of NHGRI doesn t include proposed timelines. Also moving forward with its genomics http://pubs.acs.org/cen/topstory/8116/8116notw6.html

Table of Contents cen-chemjobs.org Today's Headlines Editor's Page ... What's That Stuff? Back Issues Safety Letters Chemcyclopedia ACS Members can Join ACS April 21, Volume 81, Number 16 CENEAR 81 16 p. 9 ISSN 0009-2347 GENOMICS HUMAN GENOME PROJECT FINISHED International consortium announces all original goals met, plans for future CELIA HENRY A t a symposium held last week to mark the 50th anniversary of the double helix structure of DNA, Francis S. Collins, director of NIH's National Human Genome Research Institute (NHGRI), announced that he was "pleased and exhilarated" to "declare the goals of the Human Genome Project to be completed." At the same meeting, Collins released NHGRI's vision for the future of genomic research. "The genome era is now a reality," he said. Collins The genome sequencing effort was completed ahead of schedule and under budget, Collins said. When officially started in 1990, the project was expected to take 15 years with a U.S. contribution of $3 billion. Instead, it has taken less than 13 years and cost $2.6 billion. The U.S. portion was led by NHGRI and the Department of Energy. The question of how this sequence differs from the draft sequence published in February 2001 was addressed by Robert H. Waterston, a scientist at the Genome Sequencing Center at Washington University in St. Louis, one of the U.S. facilities involved with the genome project. His answer: "completeness and continuity." The "finished" draft covers 99% of the genome and closes 99.5% of the gaps in the rough draft. Closing those gaps wasn't easy. "Like climbing Mount Everest, the last 10% is the greatest challenge," Waterston said.

129. Genome ProjectGenome Project The United States Human Genome Project (HGP) began October 1, The Human Genome Project Examining The Arc s Concerns Regarding the Project s Ethical, http://www.thearc.org/depts/genome.html

The Arc's Human Genome Education Project If you could develop a "cure" for mental retardation, would you? Do you feel a woman should have a right to refuse prenatal testing? Do you think employers or insurance companies should be allowed to discriminate on the basis of a person's genes? These are only some of the many controversial questions that The Arc's Human Genome Education Project Project addressed during the past three years as we sought to educate our members about the ethical, legal and social issues surrounding genetic research and mental retardation. The Arc of the United States, a national organization on mental retardation with 140,000 members and more than 1,000 affiliated chapters, received a grant from the U.S. Department of Energy to develop educational materials and conduct training relating to the ethical, legal and social implications of genetic knowledge and use. The Human Genome Project Defined The United States' Human Genome Project (HGP) began October 1, 1990 as part of an international effort to determine the location and structure of the entire set of human genes. Human genome efforts in the U.S. are currently being directed by the National Institutes of Health (NIH) and the Department of Energy (DOE). Why Is The Arc Involved?

130. The Human Genome Project The Human Genome Project (HGP) was started in the late 1980’s to construct detailed genetic and physical maps of the human genome. http://www.health.ri.gov/genetics/hgp.php

Home Health Topics News Data ... Site Map Programs Genetics Homepage About Genetics Ethical Issues Genetic Counseling ... Pending Federal Legislation Rhode Island Department of Health Genetics Core Team 3 Capitol Hill, Providence, Rhode Island, 02908 Sharon Marable, MD, MPH Assistant Medical Director, Disease Prevention and Control Leonard Green, MPS Chief, Vital Records Rhode Island Department of Health Genetics Website The Human Genome Project The Human Genome Project (HGP was started in the late 1980’s to construct detailed genetic and physical maps of the human genome. It will identify the estimated 50,000-100,000 genes within the human genome, and determine the sequence of the 3 billion chemical bases. The HGP will comprise a resource of detailed information about the structure, organization and function of human DNA, information that constitutes the basic set of inherited "instructions" for the development and functioning of a human being. The study of all of the genes in an organism (or genome) is called genomics. In the United States, the Department of Energy (DOE) and the National Institutes of Health (NIH) are the main research agencies within the U.S. government responsible for developing and planning the project, but the HGP is an international research program. There are also private companies, like Celera and HGSI, who are working on genomics research simultaneously with the HGP.

131. The San Antonio Genome Center at San Antonio. Human Genome Project Project 1 Polymorphic and Expressed Markers for Human Chromosome 3, directed by Sue Naylor http://apollo.uthscsa.edu/

The University of Texas Health Science Center at San Antonio Human Genome Project Chromosome 3 Research DATABASE FOR CHROMOSOME 3 MARKERS AND CLONES Our public access database offers information (names, genetic positions, primer sequences, sizes, clones, etc.) on STS, EST, Probes, BAC, PAC and Cosmids. Helpful hints for finding clones and sequences. BAC CONTIGS OF CHROMOSOME 3 In collaboration with the Baylor College of Medicine Genome Center, Sue Naylor is constructing BAC contigs of chromosome 3. The draft sequence of chromosome 3 is being compiled from several different sources. CONTIGS FOR DRAFT SEQUENCE All of the data seen on this page is due to the hard work and dedication of past and present members of The Naylor Lab Genome Group: Dawn Garcia, Xin He, Gabe Barrera, Kenny Jastrow, Teresita Martinez, Ana Villasenor, Nicole Buzello, Lisa Trevino, Tammy Morrish, Jason Hawkins and Shanna Moore. We especially thank our informatics expert Ruben Rodriguez for designing and maintaining this web page. Note: There are still frequent updates to the sequence and e-PCR database. For the latest results of each clone, check the ePCR site at

132. Closed Provides resources for research workers in the fields of genomics, genetics and functional genomics. Funded by the United Kingdom Medical Research Council. http://www.hgmp.mrc.ac.uk/

HGMP/RFCGR has Closed The MRC have closed down the HGMP/RFCGR. Some Services have Moved: Please modify your bookmarks Geneservice has moved to: http://www.geneservice.co.uk/ FUGU Fugu has moved to: http://fugu.biology.qmul.ac.uk/ Bioinformatics Bioinformatics has moved to: LITBIO

133. UCSC Genome Browser Home It also provides a portal to the ENCODE Project. Mmul_0.1 (UCSC version rheMac1), produced by the Baylor College of Medicine Human Genome Sequencing http://genome.ucsc.edu/

Genomes Blat Tables Gene Sorter ... Contact Us About the UCSC Genome Bioinformatics Site This site contains the reference sequence and working draft assemblies for a large collection of genomes. It also provides a portal to the ENCODE project. We encourage you to explore these sequences with our tools. The Genome Browser zooms and scrolls over chromosomes, showing the work of annotators worldwide. The Gene Sorter shows expression, homology and other information on groups of genes that can be related in many ways. Blat quickly maps your sequence to the genome. The Table Browser provides convenient access to the underlying database. News To receive announcements of new genome assembly releases, new software features, updates and training seminars by email, subscribe to the genome-announce mailing list. 11 August 2005 - Upcoming Genome Browser Seminars - San Francisco, Seattle, Chicago, Boston, Philadelphia, Atlanta The UCSC Bioinformatics Group announces six regional seminars and hands-on computer workshops on the UCSC Genome Browser, presented by

134. Bioinformatics Resource Centre Provides registered users access to a comprehensive range of programs and databases to aid genomic and proteomic research, including training and help desk from the MRC Human Genome Mapping Project (UK). Registration necessary. http://www.hgmp.mrc.ac.uk/Bioinformatics/

135. Human Genome Mapping Project A list of features for meckelgruber syndrome, also known as dysencephalia splanchocystica. http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?1095

136. Human Genome Mapping Project A list of features for Aarskog syndrome. http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?2

137. Human Genome Mapping Project A list of features for AblepharonMacrostomia Syndrome. http://www.hgmp.mrc.ac.uk/dhmhd-bin/hum-look-up?1084

138. Stanford University - Morrison Institute - The Human Genome Diversity Project The Human Genome Diversity Project is an international Project that seeks to understand the diversity and unity of the entire Human species. http://www.stanford.edu/group/morrinst/hgdp.html

Home About the Institute Colloquia Financial Assistance (Stanford) Human Genome Diversity Project Related Organizations The Human Genome Diversity Project is an international project that seeks to understand the diversity and unity of the entire human species. The HGD Project is in its planning stages. Several documents are now available: the Model Ethical Protocol for Collecting DNA Samples; Protocolo Ético Modelo para la Recolección de Muestras de ADN Comité Regional Norteamericano Proyecto de la Diversidad del Genoma Humano, translated by Leticia Molinero (acknowledgments also to Leticia Britos and Lisa Diamond); Frequently Asked Questions about the HGDP; the Alghero Summary Report , a summary of the purpose of the Project and of the planning work done as of September 1993; statement of Mary-Claire King to the National Academy of Sciences committee charged with evaluating the Human Genome Diversity Project, September 16, 1996; committee members related sites Questions/comments/suggestions to Morrison Institute

139. Glossaries: Human Genetics/Genome Project Glossaries, dictionaries, and terms in Human, clinical, and medical genetics. http://www.kumc.edu/gec/glossary.html

Glossaries of Genome / Human Genetics Terms Glossaries and terms for specific conditions Glossary of Genetic Terms Genetics Education Center, Univ. Kansas Medical Center Glossary of Genetics , (illustrations /oral descriptions), National Human Genome Research Institute, includes spectral karyotype (SKY) term and illustration Understanding Gene Testing Glossary U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute (spanish version) Illustrated Glossary , GeneReviews Biotechnology Glossary , SDPatel and SMaulik, GeneEd, Celera (not available Sept 2002) Dictionary of Genetic Terms Dictionary Genetics Science and Technology , Academic Press (not available Sept 2002) DNA From the Beginning Dictionary of Cell and Molecular Biology Dictionary of Genetic Terms , Genomics and Its Impact on Medicine and Society: A 2001 Primer Dictionary of Genetics Science and Technology , graphics, searchable, Academic Press (not available Sept 2002) GeneCards , Weizmann Institute of Science Genome Glossary , Department of Energy (DOE) Genetic Glossary , cross referenced,Biology Teaching Organisation (BTO), University of Edinburgh, Biology Curriculum

140. The Sanger Institute: Cancer Genome Project An initiative dedicated to using the Human Genome sequence and high throughput mutationdetection techniques to identify genes critical in the development of Human cancers. http://www.sanger.ac.uk/genetics/CGP/

Sanger Home Acedb YourGenome Ensembl ... News CGP Home Publications Conditions of use Search WWW Site ... FTP Site The Cancer Genome Project Summary All cancers occur due to abnormalities in DNA sequence. Throughout life, the genome within cells of the human body is exposed to mutagens and suffers mistakes in replication. These corrosive influences result in progressive, subtle divergence of the DNA sequence in each cell from that originally constituted in the fertilised egg. Occasionally, one of these somatic mutations alters the function of a critical gene, providing growth advantage to the cell in which it has occurred and resulting in the emergence of an expanded clone derived from this cell. Acquisition of additional mutations, and consequent waves of clonal expansion result in the evolution of the mutinous cells that invade surrounding tissues and metastasise. One in three people in the Western world develop cancer and one in five die of the disease. Cancer is therefore the commonest genetic disease. The identification of genes that are mutated and hence drive oncogenesis has been a central aim of cancer research since the advent of recombinant DNA technology. The Cancer Genome Project is using the human genome sequence and high throughput mutation detection techniques to identify somatically acquired sequence variants/mutations and hence identify genes critical in the development of human cancers. This initiative will ultimately provide the paradigm for the detection of germline mutations in non-neoplastic human genetic diseases through genome-wide mutation detection approaches.

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