61. Origins Of The Human Genome Project The Human Genome Project was borne of technology, grew into a science bureaucracy in 34 Jorge E. Allende, Background on the Human Genome Project (Red http://www.fplc.edu/risk/vol5/spring/cookdeeg.htm

Origins of the Human Genome Project Robert Mullan Cook-Deegan* Introduction The earliest and most obvious applications of genome research are tests for genetic disorders, but less obvious diagnostic uses may prove at least as important, such as forensic uses to establish identity (to determine paternity, to link suspects of physical evidence of rape or murder, or as a molecular "dog-tag" in the military). Genome research also promises to find genes expeditiously, making the genetic approach attractive as a first step in the study not only of complex diseases, but also of normal biological function. Each new gene is a potential target for drug development to fix it when broken, to shut it down, to attenuate or amplify its expression, or to change its product, usually a protein. Finding a gene gives investigators a molecular handle on problems that have proven intractable. Faith that the systematic analysis of DNA structure will prove to be a powerful research tool underlies the rationale behind the genome project. Faith that that scientific power will translate to products, jobs and wealth underlies the recent substantial investments in private genome research startup companies and the diversification of pharmaceutical and agricultural research firms into genome research. The human genome project was borne of technology, grew into a science bureaucracy in the U.S. and throughout the world and is now being transformed into a hybrid academic and commercial enterprise. The next phase of the project promises to veer more sharply toward commercial application, exploiting the rapidly growing body of knowledge about DNA structure to the pursuit of practical benefits.

62. CNN.com - Quick Breakthroughs From Human Genome Project - September 12, 2000 CNN http://www.cnn.com/2000/HEALTH/09/12/genome.progress.reut/index.html

health Editions myCNN Video ... Feedback CNN Sites CNN CNN Europe CNNfn CNNSI myCNN CNNfyi AllPolitics Languages Search CNN.com CNNSI.com CNNfn.com The Web HEALTH TOP STORIES New treatments hold out hope for breast cancer patients MORE TOP STORIES Thousands dead in India; quake toll rapidly rising Israelis, Palestinians make final push before Israeli election Davos protesters confront police MORE ... MORE MARKETS 4:30pm ET, 4/16 DJIA NAS SPORTS Jordan says farewell for the third time ... LOCAL EDITIONS: CNN.com Europe change default edition MULTIMEDIA: video video archive audio multimedia showcase ... more services E-MAIL: Subscribe to one of our news e-mail lists Enter your address: DISCUSSION: chat feedback CNN WEB SITES: CNNfyi.com CNN.com Europe AsiaNow Spanish ... Korean Headlines TIME INC. SITES: Go To ... Time.com People Money Fortune EW CNN NETWORKS: CNN anchors transcripts Turner distribution SITE INFO: help contents search ad info ... jobs WEB SERVICES: Quick breakthroughs from human genome project BETHESDA, Maryland (Reuters) Years of work await scientists who are starting to read the "book of life" the human genome but some surprisingly quick breakthroughs are also being made, the head of the project said Monday. Because so many scientists are working so hard to make public their findings on human genetic information, a startling number of little changes that make one person different from another known as single nucleotide polymorphisms or SNPs have been identified.

63. Introduction - The Human Genome Project New maps developed through the Human Genome Project will enable researchers This new effort the Human Genome Project - is expected to take 15 years to http://www.accessexcellence.org/RC/AB/IE/Intro_The_Human_Genome.html

Introduction - The Human Genome Project National Center for Human Genome Research, National Institutes of Health. "New Tools for Tomorrow's Health Research." Bethesda, MD: Department of Health and Human Services, 1992. Since the beginning of time, people have yearned to explore the unknown, chart where they have been, and contemplate what they have found. The maps we make of these treks enable the next explorers to push ever farther the boundaries of our knowledge - about the earth, the sea, the sky, and indeed, ourselves. On a new quest to chart the innermost reaches of the human cell, scientists have now set out on biology's most important mapping expedition: the Human Genome Project. Its mission is to identify the full set of genetic instructions contained inside our cells and to read the complete text written in the language of the hereditary chemical DNA (deoxyribonucleic acid). As part of this international project, biologists, chemists, engineers, computer scientists, mathematicians, and other scientists will work together to plot out several types of biological maps that will enable researchers to find their way through the labyrinth of molecules that define the physical traits of a human being.

64. Chromosome Number 02 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2202

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 02 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 02 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 6.27 MB main site mirror sites Plain text zip 1.86 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

65. Ethical Issues Of The Human Genome Project Ethical Issues of the Human Genome Project. Mapping and Sequencing the Human Genome Science, Ethics, and Public Policy. http://www.accessexcellence.org/RC/AB/IE/Ethical_Issues_of_the_HGP.html

Ethical Issues of the Human Genome Project "Mapping and Sequencing the Human Genome: Science, Ethics, and Public Policy." Developed by BSCS, in collaboration with the American Medical Association, under the U.S. Department of Energy Grant #DE-FG02-91ER61147. Critics express several concerns about the Human Genome Project (HGP), and most involve the extent of the project or its funding. Original proposals for the project emphasized sequencing the entire human genome. This goal, however, is controversial because of the high cost and because many critics believe that sequencing a huge amount of noncoding DNA should have low priority in a time of limited funds for research. On the other hand, most individuals involved in the project agree that detailed genetic and physical maps would be extremely useful. Therefore, mapping of the genome now is the primary goal, with complete sequencing to follow only if the cost becomes reasonable. Only about 5 percent of the genome contains sequences that are coding regions, and some biologists still maintain there is little point in sequencing the other 95 percent. Because biologists already know that several regulatory signals are in noncoding regions of DNA, a compromise has been reached. A few pilot sequencing projects are focusing on sequencing certain coding regions that are most likely to contain information valuable to the medical and biological communities. A major criticism of the HGP is similar to that raised against other mega-science projects such as the space station or the superconducting supercollider: The high cost is not justified. This big science vs. little science argument maintains that funding such large-scale projects takes scarce resources from researchers who may study certain areas of particular interest more efficiently. Conversely, others argue that coordination of the HGP is a more efficient way to conduct research in human genetics because it minimizes duplication of effort.

66. CNN Specials - Blueprint Of The Body of thousands of genes in the human body, collectively known as the genome, Human Genome Project Robert CookDeegan Author, Gene Wars Eric Lander http://www.cnn.com/SPECIALS/2000/genome/

In-depth Archive Bradman: Cricket's greatest legend Kashmir: Where conflict rules Shadows over Indonesia The Reagan Years All-Stars Too Soon: The NBA's Age Dilemma Falun Gong: China's Dilemma Grammy Awards Ice Run: Submarine to the Arctic George W. Bush Inauguration A Decade Since Desert Storm India Quake: From holiday to horror The Clinton Years Power Crisis Year in Review 2000 Bush Presidency: Europe's View US Election 2000: Europe's View Your Business/Your World Yugoslavia in Transition New Germany City Limits Denmark Decides Yugoslav Elections Europe's Fuel Crisis Northern Ireland Changing Face of Europe Democracy in America Galveston Hurricane Colombia Mideast Peace Election 2000 Human Genome Korea at 50 Specials by year CNN.com Sections WORLD U.S. WEATHER BUSINESS SPORTS SCI-TECH SPACE HEALTH ENTERTAINMENT POLITICS LAW TRAVEL IN-DEPTH LOCAL myCNN Top Stories A computer monitor displays DNA being sequenced. The four colors represent the four chemicals that make up the instructions for DNA. On the threshold of a brave new world Two separate groups of researchers have published the results of their quest to produce the master blueprint of a human in scientific journals. The massive database of the tens of thousands of genes in the human body, collectively known as the genome, promises to revolutionize medicine in the coming decades.

67. Chromosome Number 03 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2203

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 03 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 03 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 3.92 MB main site mirror sites Plain text zip 1.16 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

68. CNN Specials - Blueprint Of The Body: Overview The findings of the publicly funded AngloUS Human Genome Project were Collins heads the Human Genome Project, a consortium of 1100 scientists from four http://www.cnn.com/SPECIALS/2000/genome/story/overview/

In-depth Archive Bradman: Cricket's greatest legend Kashmir: Where conflict rules Shadows over Indonesia The Reagan Years All-Stars Too Soon: The NBA's Age Dilemma Falun Gong: China's Dilemma Grammy Awards Ice Run: Submarine to the Arctic George W. Bush Inauguration A Decade Since Desert Storm India Quake: From holiday to horror The Clinton Years Power Crisis Year in Review 2000 Bush Presidency: Europe's View US Election 2000: Europe's View Your Business/Your World Yugoslavia in Transition New Germany City Limits Denmark Decides Yugoslav Elections Europe's Fuel Crisis Northern Ireland Changing Face of Europe Democracy in America Galveston Hurricane Colombia Mideast Peace Election 2000 Human Genome Korea at 50 Specials by year CNN.com Sections WORLD U.S. WEATHER BUSINESS SPORTS SCI-TECH SPACE HEALTH ENTERTAINMENT POLITICS LAW TRAVEL IN-DEPTH LOCAL myCNN Top Stories On the threshold of a brave new world By Carol Clark CNN Interactive Information on DNA is written in a four-letter code with each letter corresponding to DNA's chemical components, adenine (A), thymine (T), cytocine (C) and guanine (G). Each band above represents one of the letters. (CNN) Two separate groups of researchers published the results of their quest to produce the master blueprint of a human in scientific journals on February 12, 2001.

69. Chromosome Number 04 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2204

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 04 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 04 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 10.10 MB main site mirror sites Plain text zip 2.99 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

70. Human Genome human genome sequencing, mapping, analysis, bac map and finished sequence. Human Genome Project BAC and Accession Maps http://www.genome.wustl.edu/projects/human/index.php?fpc=1

71. Chromosome Number 05 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2205

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 05 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 05 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 11.93 MB main site mirror sites Plain text zip 3.53 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

72. Reading The Human Map - Human Genome Project NSLS Genome Project Newsletter National Local Resources NSLS Grant Project Background Ethical, Legal and Social Issues Tool Kit for Libraries http://www.nsls.info/genome/

73. Chromosome Number 06 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2206

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 06 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 06 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 31.73 MB main site mirror sites Plain text zip 9.38 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

74. Chromosome Number 07 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2207

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 07 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 07 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 69.97 MB main site mirror sites Plain text zip 20.68 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

75. Genomics|Training|Human Genome Project The mission of the Office of Genomics and Disease Prevention is to integrate advances in human genetics into public health research, policy, and programs. http://www.cdc.gov/genomics/info/genome.htm

home training resources and tools human genome project Human Genome Project Links to non-Federal organizations found at this site are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the Federal Government, and none should be inferred. The CDC is not responsible for the content of the individual organization Web pages found at these links. Department of Energy Information about the U.S. Human Genome Project. The site is linked to a more technical Research site. Both web sites are funded by the U.S. Department of Energy Human Genome Program. Human genome resources From the National Center for Biotechnology Information (NCBI) Information on the Environmental Genome Project Information about the National Institute of Environmental Health Sciences plan to expand research on genetic susceptibility to environmentally-associated diseases through a new Environmental Genome Project. Initial sequencing and analysis of the human genome International Human Genome Sequencing Consortium Nature (February, 2001)

76. Chromosome Number 08 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2208

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 08 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 08 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 5.53 MB main site mirror sites Plain text zip 1.64 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

77. Genomics|Info|Perspectives|Human Genome Project The mission of the Office of Genomics and Disease Prevention is to integrate advances in human genetics into public health research, policy, and programs. http://www.cdc.gov/genomics/info/perspectives/hgproject.htm

home training perspectives human genome project Welcome to A Public Health Perspective, the Office of Genomics and Disease Prevention's highlights page. Researching the weekly update, OGDP finds scientific literature that reports on discoveries of genetic variants, related disease outcomes, and the complex social, legal, and ethical issues surrounding genetic discoveries. A Public Health Perspective focuses on a single topic and provides you with information relevant to public health practice. This week we are examining the public health perspective of the Human Genome Project. (June 2000) " As the work of the Human Genome Project progresses, opportunities to use genetic information safely and effectively to improve health and prevent disease will continue to emerge. Gene sequencing and discovery are only the beginning." Muin J. Khoury MD,PhD, Director, Office of Genomics and Disease Prevention Public Health Perspective Menu The Public Health Perspective Genetic Information The Human Genome Project Information Reader's Forum The Public Health Perspective Gene Sequencing and Discovery are only the Beginning.

78. Chromosome Number 09 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2209

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 09 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 09 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 4.53 MB main site mirror sites Plain text zip 1.34 MB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

79. Beyond The Human Genome Project The completion of the Human Genome Project, and the sequencing of other organims DNA, The Human Genome Project is an effort to understand the genetic http://www2.dof.hmc.edu/hgp/default.html

80. Chromosome Number 10 By Human Genome Project - Project Gutenberg Human Genome Project. Downloadable etext from Project Gutenberg. http://www.gutenberg.net/etext/2210

Project Gutenberg Online Book Catalog Quick Search Author: Title Word(s): EText-No.: Advanced Search Recent Books Top 100 Offline Catalogs ... In Depth Information Chromosome Number 10 by Human Genome Project Read online Help on this page New Search Bibliographic Record Creator Human Genome Project Title Chromosome Number 10 LoC Class QH: Science: Natural history Subject Human Genome Project Subject Human gene mapping Subject Human genetics EText-No. Release Date No Formats Available For Download Edition Format Encoding ¹ Compression Size Download Links ² Plain text none 3.13 MB main site mirror sites Plain text zip 952 KB main site mirror sites ¹ If you need a special character set, try our online recoding service ² If you are located outside the U.S. you may want to download from a mirror site located near you to improve performance. Click on mirror sites to select a mirror site. If you have P2P software installed that understands magnetlinks click on Most recently updated: 2005-09-08 07:15:23

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